Cardiac contractility modulation increases action potential duration dispersion and decreases ventricular fibrillation threshold via β1-adrenoceptor activation in the crystalloid perfused normal rabbit heart

International Journal of Cardiology

Volumn 172, Issue 1, 2014, Pages 144-154

  Winter, James ^a   Brack, Kieran E ^a   Coote, John H ^b   Ng, G André ^a,c,d  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c Leicester NIHR Biomedical Research Unit in Cardiovascular Disease   (United Kingdom)

^d UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

Author keywords

Action potential duration dispersion; Cardiac contractility modulation; Non excitatory stimulation (NES); Ventricular arrhythmia; Ventricular fibrillation

Indexed keywords

ACETYLCHOLINE; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; CHOLINERGIC RECEPTOR STIMULATING AGENT; METOPROLOL; POTASSIUM CARDIOPLEGIC SOLUTION; POTASSIUM DERIVATIVE;

ACTION POTENTIAL; ANIMAL; AUTONOMIC GANGLION; AUTONOMIC NERVOUS SYSTEM; DRUG EFFECTS; HEART; HEART CONTRACTION; HEART FUNCTION TEST; HEART PACING; INNERVATION; MALE; PATHOPHYSIOLOGY; PERFUSION; PHYSIOLOGY; RABBIT; VENTRICULAR FIBRILLATION;

ACETYLCHOLINE; ACTION POTENTIALS; ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANIMALS; AUTONOMIC NERVOUS SYSTEM; CARDIAC PACING, ARTIFICIAL; CHOLINERGIC AGONISTS; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; GANGLIA, AUTONOMIC; HEART; MALE; METOPROLOL; MYOCARDIAL CONTRACTION; PERFUSION; POTASSIUM COMPOUNDS; RABBITS; RECEPTORS, ADRENERGIC, BETA-1; VENTRICULAR FIBRILLATION;

EID: 84894048620     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.12.184     Document Type: Article

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