Quantitative Fluorescence Spectroscopy in Strongly Scattering Media Containing Multiple Fluorophores

Optics InfoBase Conference Papers

Volumn , Issue , 1998, Pages 70-75

  Cerussi, Albert ^a   Fantini, Sergio ^a   Gratton, Enrico ^a  

^a University of Illinois at Urbana Champaign   (United States)

Author keywords

Diffusion Theory; Fluorescence Lifetime; Fluorescence Spectroscopy; Tissue Spectroscopy

Indexed keywords

FLUOROPHORES;

DIFFUSION THEORY; FLUORESCENCE LIFETIMES; FREQUENCY-DOMAIN PARAMETERS; MODULATION FREQUENCIES; PHOTON DENSITIES; PREDICTION-BASED; SCATTERING MEDIUM; SOURCE-DETECTOR SEPARATION; TISSUE SPECTROSCOPY; TURBID MEDIA;

FLUORESCENCE SPECTROSCOPY;

EID: 84894000351     PISSN: None     EISSN: 21622701     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (13)

1. See for example the chapters listed in "Topics in Fluorescence Spectroscopy, Volume 4: Probe Design and Chemical Sensing", edited by J. R. Lakowicz, (Plenum, NY, 1994).
2. M. S. Patterson and B. W. Pogue, "Mathematical model for time-resolved and frequency-domain fluorescence spectroscopy in biological tissues," Appl. Opt. 33, 1963-1974 (1994).
3. A. E. Cerussi, J. S. Maier, S. Fantini, M. A. Franceschini, W. W. Mantulin, and E. Gratton, "Experimental verification of a theory for the time-resolved fluorescence spectroscopy of thick tissues," Appl. Opt. 36, 116-124 (1997).
4. X. D. Li, M. A. O'Leary, D. A. Boas, B. Chance, and A. G. Yodh, "Fluorescent diffuse photon density waves in homogeneous and heterogeneous turbid media: Analytic solutions and applications," Appl. Opt. 35, 3746-3758 (1996).
5. D. Paithankar, A. U. Chen, B. W. Pogue, M. S. Patterson, and E. M. Sevick-Muraca, "Imaging of fluorescent yield and lifetime from multiply scattered light reemitted from random media," Appl. Opt. 36, 2260-2272 (1997).
6. M. A. O'Leary, D. A. Boas, X. D. Li, B. Chance, and A. G. Yodh, "Fluorescence lifetime imaging in turbid media," Opt. Lett. 21, 158-160 (1996).
7. M. S. Patterson, B. Chance, and B. C. Wilson, "Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties," Appl. Opt. 28, 2331-2336 (1989).
8. J. B. Fishkin and E. Gratton, "Propagation of photon-density waves in strongly scattering media containing an absorbing semi-infinite plane bounded by a straight edge," J. Opt. Soc. Am. A. 10, 127-140 (1993).
9. Molecular Probes provided the spectral data parameters for the sample lot number, but did not provide measurement errors for those parameters.
10. G. G. Guilbault, "General aspects of luminescence spectroscopy," Practical Fluorescence ed. by G. G. Guilbault, pp. 15-16 (Marcel Decker, NY, 1990).
11. B. Feddersen, D. W. Piston, and E. Gratton, "Digital parallel acquisition in frequency-domain fluorimetry," Rev. Sci. Instr. 60, 2929-2936 (1989).
12. S. Fantini, M. A. Franceschini, J. B. Fishkin, B. Barbieri, and E. Gratton, "Quantitative determination of the absorption spectra of chromophores in strongly scattering media: A light emitting diode based technique," Appl. Opt. 33, 5204-5213 (1994).
13. J. S. Maier, A. E. Cerussi, S. Fantini, and E. Gratton, "Experimental recovery of absorption, scattering and fluorescence parameters in highly-scattering media from a single measurement," Proc. SPIE 2979, 6-13 (1997).