메뉴 건너뛰기




Volumn 231, Issue 4, 2014, Pages 765-775

Acute effects of mecamylamine and varenicline on cognitive performance in non-smokers with and without schizophrenia

Author keywords

Attention; Cognitive function; Mecamylamine; Nicotine; Schizophrenia; Smoking; Varenicline; Working memory

Indexed keywords

ADULT; ANTIPSYCHOTIC AGENTS; ATTENTION; BENZAZEPINES; COGNITION; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MECAMYLAMINE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; QUINOXALINES; REACTION TIME; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SMOKING CESSATION; TASK PERFORMANCE AND ANALYSIS;

EID: 84893984952     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-013-3286-3     Document Type: Article
Times cited : (21)

References (49)
  • 1
    • 34548679635 scopus 로고    scopus 로고
    • Neuronal nicotinic receptors: A perspective on two decades of drug discovery research
    • 1:CAS:528:DC%2BD2sXhtVOgu7jO 17662959 10.1016/j.bcp.2007.06.033
    • Arneric SP, Holladay M, Williams M (2007) Neuronal nicotinic receptors: a perspective on two decades of drug discovery research. Biochem Pharmacol 74:1092-1101
    • (2007) Biochem Pharmacol , vol.74 , pp. 1092-1101
    • Arneric, S.P.1    Holladay, M.2    Williams, M.3
  • 3
    • 0034730801 scopus 로고    scopus 로고
    • Test-retest reliability of the dot test of visuospatial working memory in patients with schizophrenia and controls
    • 1:STN:280:DC%2BD3cvpt1Wqug%3D%3D 10978884 10.1016/S0920-9964(99)00216-9
    • Bollini AM, Arnold MC, Keefe RS (2000) Test-retest reliability of the dot test of visuospatial working memory in patients with schizophrenia and controls. Schizophr Res 45:169-173
    • (2000) Schizophr Res , vol.45 , pp. 169-173
    • Bollini, A.M.1    Arnold, M.C.2    Keefe, R.S.3
  • 4
    • 34548683244 scopus 로고    scopus 로고
    • Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys
    • 1:CAS:528:DC%2BD2sXhtVOgu7nI 17706609 10.1016/j.bcp.2007.07.010
    • Buccafusco JJ, Terry AV, Jr, Decker MW, Gopalakrishnan M (2007) Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys. Biochem Pharmacol 74:1202-1211
    • (2007) Biochem Pharmacol , vol.74 , pp. 1202-1211
    • Buccafusco, J.J.1    Terry, Jr.A.V.2    Decker, M.W.3    Gopalakrishnan, M.4
  • 5
    • 33749847812 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and tolerability after single and multiple oral doses of varenicline in elderly smokers
    • 1:CAS:528:DC%2BD28Xht1WjsbzP 17050788 10.1177/0091270006291837
    • Burstein AH, Fullerton T, Clark DJ, Faessel HM (2006) Pharmacokinetics, safety, and tolerability after single and multiple oral doses of varenicline in elderly smokers. J Clin Pharmacol 46:1234-1240
    • (2006) J Clin Pharmacol , vol.46 , pp. 1234-1240
    • Burstein, A.H.1    Fullerton, T.2    Clark, D.J.3    Faessel, H.M.4
  • 7
    • 0023790621 scopus 로고
    • The Continuous Performance Test, identical pairs version (CPT-IP): I. New findings about sustained attention in normal families
    • 1:STN:280:DyaL1M7osFWlsg%3D%3D 3237915 10.1016/0165-1781(88)90076-5
    • Cornblatt BA, Risch NJ, Faris G, Friedman D, Erlenmeyer-Kimling L (1988) The Continuous Performance Test, identical pairs version (CPT-IP): I. New findings about sustained attention in normal families. Psychiatry Res 26:223-238
    • (1988) Psychiatry Res , vol.26 , pp. 223-238
    • Cornblatt, B.A.1    Risch, N.J.2    Faris, G.3    Friedman, D.4    Erlenmeyer-Kimling, L.5
  • 8
    • 0024382649 scopus 로고
    • The continuous performance test, identical pairs version: II. Contrasting attentional profiles in schizophrenic and depressed patients
    • 1:STN:280:DyaL1MzmslKgug%3D%3D 2772099 10.1016/0165-1781(89)90188-1
    • Cornblatt BA, Lenzenweger MF, Erlenmeyer-Kimling L (1989) The continuous performance test, identical pairs version: II. Contrasting attentional profiles in schizophrenic and depressed patients. Psychiatry Res 29:65-85
    • (1989) Psychiatry Res , vol.29 , pp. 65-85
    • Cornblatt, B.A.1    Lenzenweger, M.F.2    Erlenmeyer-Kimling, L.3
  • 10
    • 84856117087 scopus 로고    scopus 로고
    • Schizophrenia and tobacco smoking comorbidity: NAChR agonists in the treatment of schizophrenia-associated cognitive deficits
    • 3116036 21288470 10.1016/j.neuropharm.2011.01.044
    • D'Souza MS, Markou A (2012) Schizophrenia and tobacco smoking comorbidity: nAChR agonists in the treatment of schizophrenia-associated cognitive deficits. Neuropharmacology 62:1564-1573
    • (2012) Neuropharmacology , vol.62 , pp. 1564-1573
    • D'Souza, M.S.1    Markou, A.2
  • 11
    • 33947158101 scopus 로고    scopus 로고
    • Effects of TC-1734 (AZD3480), a selective neuronal nicotinic receptor agonist, on cognitive performance and the EEG of young healthy male volunteers
    • 1:CAS:528:DC%2BD2sXis1erurc%3D 10.1007/s00213-006-0675-x
    • Dunbar G, Boeijinga PH, Demazieres A, Cisterni C, Kuchibhatla R, Wesnes K, Luthringer R (2007) Effects of TC-1734 (AZD3480), a selective neuronal nicotinic receptor agonist, on cognitive performance and the EEG of young healthy male volunteers. Psychopharmacology (Berl) 191:919-929
    • (2007) Psychopharmacology (Berl) , vol.191 , pp. 919-929
    • Dunbar, G.1    Boeijinga, P.H.2    Demazieres, A.3    Cisterni, C.4    Kuchibhatla, R.5    Wesnes, K.6    Luthringer, R.7
  • 12
    • 0029972206 scopus 로고    scopus 로고
    • Mecamylamine does not precipitate withdrawal in cigarette smokers
    • 1:CAS:528:DyaK28XnsVentbw%3D
    • Eissenberg T, Griffiths RR, Stitzer ML (1996) Mecamylamine does not precipitate withdrawal in cigarette smokers. Psychopharmacology (Berl) 127:328-336
    • (1996) Psychopharmacology (Berl) , vol.127 , pp. 328-336
    • Eissenberg, T.1    Griffiths, R.R.2    Stitzer, M.L.3
  • 15
    • 33747072313 scopus 로고    scopus 로고
    • Single-dose pharmacokinetics of varenicline, a selective nicotinic receptor partial agonist, in healthy smokers and nonsmokers
    • 1:CAS:528:DC%2BD28XpvFOms7Y%3D 16920893 10.1177/0091270006290669
    • Faessel HM, Smith BJ, Gibbs MA, Gobey JS, Clark DJ, Burstein AH (2006) Single-dose pharmacokinetics of varenicline, a selective nicotinic receptor partial agonist, in healthy smokers and nonsmokers. J Clin Pharmacol 46:991-998
    • (2006) J Clin Pharmacol , vol.46 , pp. 991-998
    • Faessel, H.M.1    Smith, B.J.2    Gibbs, M.A.3    Gobey, J.S.4    Clark, D.J.5    Burstein, A.H.6
  • 19
    • 33748564313 scopus 로고    scopus 로고
    • Cognitive impairment and functional outcome in schizophrenia and bipolar disorder
    • 16965182 discussion 36-42
    • Green MF (2006) Cognitive impairment and functional outcome in schizophrenia and bipolar disorder. J Clin Psychiatry 67(Suppl 9):3-8. discussion 36-42
    • (2006) J Clin Psychiatry , vol.67 , Issue.SUPPL. 9 , pp. 3-8
    • Green, M.F.1
  • 20
    • 0038368835 scopus 로고    scopus 로고
    • Attentional effects of nicotinic agonists in rats
    • 1:CAS:528:DC%2BD3sXjvFeksb4%3D 12763099 10.1016/S0028-3908(03)00099-6
    • Hahn B, Sharples CG, Wonnacott S, Shoaib M, Stolerman IP (2003) Attentional effects of nicotinic agonists in rats. Neuropharmacology 44:1054-1067
    • (2003) Neuropharmacology , vol.44 , pp. 1054-1067
    • Hahn, B.1    Sharples, C.G.2    Wonnacott, S.3    Shoaib, M.4    Stolerman, I.P.5
  • 21
    • 77955663393 scopus 로고    scopus 로고
    • Meta-analysis of the acute effects of nicotine and smoking on human performance
    • Heishman SJ, Kleykamp BA, Singleton EG (2010) Meta-analysis of the acute effects of nicotine and smoking on human performance. Psychopharmacology (Berl) 210:453-469
    • (2010) Psychopharmacology (Berl) , vol.210 , pp. 453-469
    • Heishman, S.J.1    Kleykamp, B.A.2    Singleton, E.G.3
  • 22
    • 0030749730 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor antagonist effect of fluoxetine in rat hippocampal slices
    • Hennings EC, Kiss JP, Vizi ES (1997) Nicotinic acetylcholine receptor antagonist effect of fluoxetine in rat hippocampal slices. Brain Res 759:292-294
    • (1997) Brain Res , vol.759 , pp. 292-294
    • Hennings, E.C.1    Kiss, J.P.2    Vizi, E.S.3
  • 23
    • 83055160773 scopus 로고    scopus 로고
    • Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorder
    • 1:CAS:528:DC%2BC38Xns1SitQ%3D%3D 3618988 21810630 10.1001/ archgenpsychiatry.2011.83
    • Hong LE, Thaker GK, McMahon RP, Summerfelt A, Rachbeisel J, Fuller RL, Wonodi I, Buchanan RW, Myers C, Heishman SJ, Yang J, Nye A (2011) Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorder. Arch Gen Psychiatry 68:1195-1206
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 1195-1206
    • Hong, L.E.1    Thaker, G.K.2    McMahon, R.P.3    Summerfelt, A.4    Rachbeisel, J.5    Fuller, R.L.6    Wonodi, I.7    Buchanan, R.W.8    Myers, C.9    Heishman, S.J.10    Yang, J.11    Nye, A.12
  • 24
    • 46149097142 scopus 로고    scopus 로고
    • Effects of transdermal nicotine on episodic memory in non-smokers with and without schizophrenia
    • 1:CAS:528:DC%2BD1cXnvVKhu7Y%3D 10.1007/s00213-008-1133-8
    • Jubelt LE, Barr RS, Goff DC, Logvinenko T, Weiss AP, Evins AE (2008) Effects of transdermal nicotine on episodic memory in non-smokers with and without schizophrenia. Psychopharmacology (Berl) 199:89-98
    • (2008) Psychopharmacology (Berl) , vol.199 , pp. 89-98
    • Jubelt, L.E.1    Barr, R.S.2    Goff, D.C.3    Logvinenko, T.4    Weiss, A.P.5    Evins, A.E.6
  • 25
    • 4544357025 scopus 로고    scopus 로고
    • Effects of nicotine and mecamylamine on cognition in rhesus monkeys
    • 1:CAS:528:DC%2BD2cXnt1Grtrc%3D 10.1007/s00213-004-1804-z
    • Katner SN, Davis SA, Kirsten AJ, Taffe MA (2004) Effects of nicotine and mecamylamine on cognition in rhesus monkeys. Psychopharmacology (Berl) 175:225-240
    • (2004) Psychopharmacology (Berl) , vol.175 , pp. 225-240
    • Katner, S.N.1    Davis, S.A.2    Kirsten, A.J.3    Taffe, M.A.4
  • 26
    • 0029131746 scopus 로고
    • A pen-and-paper human analogue of a monkey prefrontal cortex activation task: Spatial working memory in patients with schizophrenia
    • 1:STN:280:DyaK287hsl2ktA%3D%3D 8541247 10.1016/0920-9964(95)00027-J
    • Keefe RS, Roitman SE, Harvey PD, Blum CS, DuPre RL, Prieto DM, Davidson M, Davis KL (1995) A pen-and-paper human analogue of a monkey prefrontal cortex activation task: spatial working memory in patients with schizophrenia. Schizophr Res 17:25-33
    • (1995) Schizophr Res , vol.17 , pp. 25-33
    • Keefe, R.S.1    Roitman, S.E.2    Harvey, P.D.3    Blum, C.S.4    Dupre, R.L.5    Prieto, D.M.6    Davidson, M.7    Davis, K.L.8
  • 27
    • 34247398757 scopus 로고    scopus 로고
    • Stroop interference and attention-deficit/hyperactivity disorder: A review and meta-analysis
    • 17402825 10.1037/0894-4105.21.2.251
    • Lansbergen MM, Kenemans JL, van Engeland H (2007) Stroop interference and attention-deficit/hyperactivity disorder: a review and meta-analysis. Neuropsychology 21:251-262
    • (2007) Neuropsychology , vol.21 , pp. 251-262
    • Lansbergen, M.M.1    Kenemans, J.L.2    Van Engeland, H.3
  • 28
    • 0030297344 scopus 로고    scopus 로고
    • Nicotine-haloperidol interactions and cognitive performance in schizophrenics
    • 1:CAS:528:DyaK28XmvFWkt7g%3D 8914115 10.1016/S0893-133X(96)00018-8
    • Levin ED, Wilson W, Rose JE, McEvoy J (1996) Nicotine-haloperidol interactions and cognitive performance in schizophrenics. Neuropsychopharmacology 15:429-436
    • (1996) Neuropsychopharmacology , vol.15 , pp. 429-436
    • Levin, E.D.1    Wilson, W.2    Rose, J.E.3    McEvoy, J.4
  • 29
    • 0034849954 scopus 로고    scopus 로고
    • Effects of chronic nicotine and methylphenidate in adults with attention deficit/hyperactivity disorder
    • 1:CAS:528:DC%2BD3MXmtVKqur0%3D 11519638 10.1037/1064-1297.9.1.83
    • Levin ED, Conners CK, Silva D, Canu W, March J (2001) Effects of chronic nicotine and methylphenidate in adults with attention deficit/hyperactivity disorder. Exp Clin Psychopharmacol 9:83-90
    • (2001) Exp Clin Psychopharmacol , vol.9 , pp. 83-90
    • Levin, E.D.1    Conners, C.K.2    Silva, D.3    Canu, W.4    March, J.5
  • 31
    • 22444441357 scopus 로고    scopus 로고
    • Mecamylamine moderates cue-induced emotional responses in smokers
    • 15833578 10.1016/j.addbeh.2004.08.020
    • McClernon FJ, Rose JE (2005) Mecamylamine moderates cue-induced emotional responses in smokers. Addict Behav 30:741-753
    • (2005) Addict Behav , vol.30 , pp. 741-753
    • McClernon, F.J.1    Rose, J.E.2
  • 32
    • 0028287659 scopus 로고
    • Age-related effects of the nicotinic antagonist mecamylamine on cognition and behavior
    • 1:CAS:528:DyaK2cXlsFCktr0%3D 8024677 10.1038/npp.1994.11
    • Newhouse PA, Potter A, Corwin J, Lenox R (1994) Age-related effects of the nicotinic antagonist mecamylamine on cognition and behavior. Neuropsychopharmacology 10:93-107
    • (1994) Neuropsychopharmacology , vol.10 , pp. 93-107
    • Newhouse, P.A.1    Potter, A.2    Corwin, J.3    Lenox, R.4
  • 34
    • 29944435424 scopus 로고    scopus 로고
    • Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro
    • 1:CAS:528:DC%2BD28Xhslyjuw%3D%3D 16221753 10.1124/dmd.105.006767
    • Obach RS, Reed-Hagen AE, Krueger SS, Obach BJ, O'Connell TN, Zandi KS, Miller S, Coe JW (2006) Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro. Drug Metab Dispos 34:121-130
    • (2006) Drug Metab Dispos , vol.34 , pp. 121-130
    • Obach, R.S.1    Reed-Hagen, A.E.2    Krueger, S.S.3    Obach, B.J.4    O'Connell, T.N.5    Zandi, K.S.6    Miller, S.7    Coe, J.W.8
  • 37
    • 0031044715 scopus 로고    scopus 로고
    • Effects of mecamylamine on spontaneous EEG and performance in smokers and non-smokers
    • 1:CAS:528:DyaK2sXhtlOnur4%3D 9050073 10.1016/S0091-3057(96)00183-9
    • Pickworth WB, Fant RV, Butschky MF, Henningfield JE (1997) Effects of mecamylamine on spontaneous EEG and performance in smokers and non-smokers. Pharmacol Biochem Behav 56:181-187
    • (1997) Pharmacol Biochem Behav , vol.56 , pp. 181-187
    • Pickworth, W.B.1    Fant, R.V.2    Butschky, M.F.3    Henningfield, J.E.4
  • 38
    • 0032953838 scopus 로고    scopus 로고
    • Acute effects of the selective cholinergic channel activator (nicotinic agonist) ABT-418 in Alzheimer's disease
    • 1:CAS:528:DyaK1MXivVCjtrw%3D 10.1007/s002130050897
    • Potter A, Corwin J, Lang J, Piasecki M, Lenox R, Newhouse PA (1999) Acute effects of the selective cholinergic channel activator (nicotinic agonist) ABT-418 in Alzheimer's disease. Psychopharmacology (Berl) 142:334-342
    • (1999) Psychopharmacology (Berl) , vol.142 , pp. 334-342
    • Potter, A.1    Corwin, J.2    Lang, J.3    Piasecki, M.4    Lenox, R.5    Newhouse, P.A.6
  • 39
    • 38149039394 scopus 로고    scopus 로고
    • Nicotine and clozapine effects on attentional performance impaired by the NMDA antagonist dizocilpine in female rats
    • 1:CAS:528:DC%2BD1cXltV2hsQ%3D%3D 17295931 10.1017/S1461145706007528
    • Rezvani AH, Kholdebarin E, Dawson E, Levin ED (2008) Nicotine and clozapine effects on attentional performance impaired by the NMDA antagonist dizocilpine in female rats. Int J Neuropsychopharmacol 11:63-70
    • (2008) Int J Neuropsychopharmacol , vol.11 , pp. 63-70
    • Rezvani, A.H.1    Kholdebarin, E.2    Dawson, E.3    Levin, E.D.4
  • 41
    • 0035077202 scopus 로고    scopus 로고
    • Acute effects of nicotine and mecamylamine on tobacco withdrawal symptoms, cigarette reward and ad lib smoking
    • 1:CAS:528:DC%2BD3MXitVOmur0%3D 11267622 10.1016/S0091-3057(00)00465-2
    • Rose JE, Behm FM, Westman EC (2001) Acute effects of nicotine and mecamylamine on tobacco withdrawal symptoms, cigarette reward and ad lib smoking. Pharmacol Biochem Behav 68:187-197
    • (2001) Pharmacol Biochem Behav , vol.68 , pp. 187-197
    • Rose, J.E.1    Behm, F.M.2    Westman, E.C.3
  • 42
    • 0142165019 scopus 로고    scopus 로고
    • Mecamylamine acutely increases human intravenous nicotine self-administration
    • 1:CAS:528:DC%2BD3sXosVylu7k%3D 14592683 10.1016/j.pbb.2003.08.011
    • Rose JE, Behm FM, Westman EC, Bates JE (2003) Mecamylamine acutely increases human intravenous nicotine self-administration. Pharmacol Biochem Behav 76:307-313
    • (2003) Pharmacol Biochem Behav , vol.76 , pp. 307-313
    • Rose, J.E.1    Behm, F.M.2    Westman, E.C.3    Bates, J.E.4
  • 44
    • 84855866544 scopus 로고    scopus 로고
    • Adjunctive varenicline treatment with antipsychotic medications for cognitive impairments in people with schizophrenia: A randomized double-blind placebo-controlled trial
    • 1:CAS:528:DC%2BC38XnslOkuw%3D%3D 22048460 10.1038/npp.2011.238
    • Shim JC, Jung DU, Jung SS, Seo YS, Cho DM, Lee JH, Lee SW, Kong BG, Kang JW, Oh MK, Kim SD, McMahon RP, Kelly DL (2012) Adjunctive varenicline treatment with antipsychotic medications for cognitive impairments in people with schizophrenia: a randomized double-blind placebo-controlled trial. Neuropsychopharmacology 37:660-668
    • (2012) Neuropsychopharmacology , vol.37 , pp. 660-668
    • Shim, J.C.1    Jung, D.U.2    Jung, S.S.3    Seo, Y.S.4    Cho, D.M.5    Lee, J.H.6    Lee, S.W.7    Kong, B.G.8    Kang, J.W.9    Oh, M.K.10    Kim, S.D.11    McMahon, R.P.12    Kelly, D.L.13
  • 46
    • 64749107050 scopus 로고    scopus 로고
    • Cognitive and antismoking effects of varenicline in patients with schizophrenia or schizoaffective disorder
    • 19251401 10.1016/j.schres.2009.02.001
    • Smith RC, Lindenmayer JP, Davis JM, Cornwell J, Noth K, Gupta S, Sershen H, Lajtha A (2009) Cognitive and antismoking effects of varenicline in patients with schizophrenia or schizoaffective disorder. Schizophr Res 110:149-155
    • (2009) Schizophr Res , vol.110 , pp. 149-155
    • Smith, R.C.1    Lindenmayer, J.P.2    Davis, J.M.3    Cornwell, J.4    Noth, K.5    Gupta, S.6    Sershen, H.7    Lajtha, A.8
  • 48
    • 33744903636 scopus 로고    scopus 로고
    • ABT-089, a neuronal nicotinic receptor partial agonist, for the treatment of attention-deficit/hyperactivity disorder in adults: Results of a pilot study
    • 1:CAS:528:DC%2BD28Xls1eju7c%3D 16499880 10.1016/j.biopsych.2005.10.029
    • Wilens TE, Verlinden MH, Adler LA, Wozniak PJ, West SA (2006) ABT-089, a neuronal nicotinic receptor partial agonist, for the treatment of attention-deficit/hyperactivity disorder in adults: results of a pilot study. Biol Psychiatry 59:1065-1070
    • (2006) Biol Psychiatry , vol.59 , pp. 1065-1070
    • Wilens, T.E.1    Verlinden, M.H.2    Adler, L.A.3    Wozniak, P.J.4    West, S.A.5
  • 49
    • 76649095277 scopus 로고    scopus 로고
    • Why do patients with schizophrenia smoke?
    • 20051860 10.1097/YCO.0b013e3283366643
    • Winterer G (2010) Why do patients with schizophrenia smoke? Curr Opin Psychiatry 23:112-119
    • (2010) Curr Opin Psychiatry , vol.23 , pp. 112-119
    • Winterer, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.