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Volumn 53, Issue SUPPL.2, 2013, Pages 43-53

Orally inhaled dihydroergotamine: A review

Author keywords

Acute treatment; Allodynia; Central sensitization; DHE; Dihydroergotamine; Inhaler; Migraine

Indexed keywords

ACUTE TREATMENT; ALLODYNIA; CENTRAL SENSITIZATION; DHE; DIHYDROERGOTAMINE; INHALER; MIGRAINE;

EID: 84893944228     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/head.12184     Document Type: Article
Times cited : (25)

References (43)
  • 2
    • 84944661463 scopus 로고
    • Mechanism of migraine headache and action of ergotamine tartrate
    • Graham JR, Wolff HG. Mechanism of migraine headache and action of ergotamine tartrate. Arch Neurol Psychiatry. 1938;39: 737-763.
    • (1938) Arch Neurol Psychiatry , vol.39 , pp. 737-763
    • Graham, J.R.1    Wolff, H.G.2
  • 3
    • 0010620198 scopus 로고
    • Rectal use of ergotamine tartrate and caffeine alkaloid for the relief of migraine
    • Graham Jr. Rectal use of ergotamine tartrate and caffeine alkaloid for the relief of migraine. N Engl J Med. 1954;250: 936-938.
    • (1954) N Engl J Med , vol.250 , pp. 936-938
    • Graham, J.R.1
  • 4
    • 77049265697 scopus 로고
    • Ostfeld am,wolff hg.studies on headache; central versus peripheral action of ergotamine tartrate and its relevance to the therapy of migraine headache
    • AMA
    • Goodell H, Ostfeld AM,Wolff HG.Studies on headache; central versus peripheral action of ergotamine tartrate and its relevance to the therapy of migraine headache. AMA Arch Neurol Psychiatry. 1956;76: 571-577.
    • (1956) Arch Neurol Psychiatry , vol.76 , pp. 571-577
    • Goodell, H.1
  • 5
    • 8944221904 scopus 로고
    • Dihydroergotamine in the treatment of migraine; preliminary clinical observations
    • Friedman MD, Friedman DA. Dihydroergotamine in the treatment of migraine; preliminary clinical observations. Ohio Med. 1945;41: 1099.
    • (1945) Ohio Med , vol.41 , pp. 1099
    • Friedman, M.D.1    Friedman, D.A.2
  • 6
    • 0344266975 scopus 로고
    • Parenteral use of dihydroergotamine in migraine
    • Hartman MM. Parenteral use of dihydroergotamine in migraine. Ann Allergy. 1945;3: 440-442.
    • (1945) Ann Allergy , vol.3 , pp. 440-442
    • Hartman, M.M.1
  • 7
    • 0022655199 scopus 로고
    • Repetitive intravenous dihydroergotamine as therapy for intractable migraine
    • Raskin NH. Repetitive intravenous dihydroergotamine as therapy for intractable migraine. Neurology. 1986;36: 995-997.
    • (1986) Neurology , vol.36 , pp. 995-997
    • Raskin, N.H.1
  • 8
    • 0031025119 scopus 로고    scopus 로고
    • The pharmacology of ergotamine and dihydroergotamine
    • Silberstein SD. The pharmacology of ergotamine and dihydroergotamine. Headache. 1997;37(Suppl.): 15-25.
    • (1997) Headache , vol.37 , Issue.SUPPL. , pp. 15-25
    • Silberstein, S.D.1
  • 10
    • 0021276120 scopus 로고
    • Pharmacologic actions of the main metabolites of dihydroergotamine
    • Müller-Schweinitzer E. Pharmacologic actions of the main metabolites of dihydroergotamine. Eur J Clin Pharmacol. 1984;26: 699-705.
    • (1984) Eur J Clin Pharmacol , vol.26 , pp. 699-705
    • Müller-Schweinitzer, E.1
  • 11
    • 0037318133 scopus 로고    scopus 로고
    • Ergotamine and dihydroergotamine: A review [sandoz data cited]
    • and Curr Headache Rep 2003;2: 11-18
    • Bigal ME, Tepper SJ. Ergotamine and dihydroergotamine: A review [Sandoz data cited]. Curr Pain Headache Rep. 2003;7: 55-62, and Curr Headache Rep 2003;2: 11-18.
    • (2003) Curr Pain Headache Rep , vol.7 , pp. 55-62
    • Bigal, M.E.1    Tepper, S.J.2
  • 12
    • 0028226660 scopus 로고
    • Dihydroergotamine nasal spray for the acute treatment of migraine
    • Ziegler D, Ford R, Kriegler J, et al. Dihydroergotamine nasal spray for the acute treatment of migraine. Neurology. 1994;44: 447-453.
    • (1994) Neurology , vol.44 , pp. 447-453
    • Ziegler, D.1    Ford, R.2    Kriegler, J.3
  • 13
    • 42649131701 scopus 로고    scopus 로고
    • Breath-synchronized plume-control inhaler for pulmonary delivery of fluticasone propionate
    • Shrewsbury SB, Armer TA, Newman SP, Pitcairn G. Breath-synchronized plume-control inhaler for pulmonary delivery of fluticasone propionate. Int J Pharm. 2008;356: 137-143.
    • (2008) Int J Pharm , vol.356 , pp. 137-143
    • Shrewsbury, S.B.1    Armer, T.A.2    Newman, S.P.3    Pitcairn, G.4
  • 14
    • 42049084630 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of dihydroergotamine mesylate administered via a novel (tempo) inhaler
    • Shrewsbury SB, Cook RO, Taylor G, Edwards C, Ramadan NM. Safety and pharmacokinetics of dihydroergotamine mesylate administered via a novel (TEMPO) inhaler. Headache. 2008;48: 355-367.
    • (2008) Headache , vol.48 , pp. 355-367
    • Shrewsbury, S.B.1    Cook, R.O.2    Taylor, G.3    Edwards, C.4    Ramadan, N.M.5
  • 15
    • 84856176696 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo controlled, three-period crossover study comparing the acute effects of levadex (map0004, orally inhaled dhe) and intravenous dhe on pulmonary arterial systolic pressure
    • Berenberg E, Clemons D, Kellerman D, Kori S, Noveck RJ. A randomized, double-blind, placebo controlled, three-period crossover study comparing the acute effects of LEVADEX (MAP0004, orally inhaled DHE) and intravenous DHE on pulmonary arterial systolic pressure. Headache. 2011;51: 1-66.
    • (2011) Headache , vol.51 , pp. 1-66
    • Berenberg, E.1    Clemons, D.2    Kellerman, D.3    Kori, S.4    Noveck, R.J.5
  • 16
    • 84856193424 scopus 로고    scopus 로고
    • Lack of drug interaction between the migraine drug map0004 (orally inhaled dihydroergotamine) and a cyp3a4 inhibitor in humans
    • Kellerman D, Kori S, Forst A, et al. Lack of drug interaction between the migraine drug MAP0004 (orally inhaled dihydroergotamine) and a CYP3A4 inhibitor in humans. Cephalalgia. 2011;32: 150-158.
    • (2011) Cephalalgia , vol.32 , pp. 150-158
    • Kellerman, D.1    Kori, S.2    Forst, A.3
  • 17
    • 71049141266 scopus 로고    scopus 로고
    • Reduced adverse event profile of orally inhaled dhe (map0004) vs iv dhe: Potential mechanism
    • Cook RO, Shrewsbury SB, Ramadan NM. Reduced adverse event profile of orally inhaled DHE (MAP0004) vs IV DHE: Potential mechanism. Headache. 2009;49: 1423-1434.
    • (2009) Headache , vol.49 , pp. 1423-1434
    • Cook, R.O.1    Shrewsbury, S.B.2    Ramadan, N.M.3
  • 18
    • 84893949834 scopus 로고    scopus 로고
    • Assessment of the consistency of absorption of dihydroergotamine following oral inhalation: Pooled results from four clinical studies
    • (forthcoming
    • Kellerman DJ, Forst A, Combs DL, Borland S, Kori S. Assessment of the consistency of absorption of dihydroergotamine following oral inhalation: Pooled results from four clinical studies. J Aerosol Med Pulm Drug Deliv. 2012. (forthcoming).
    • (2012) J Aerosol Med Pulm Drug Deliv
    • Kellerman, D.J.1    Forst, A.2    Combs, D.L.3    Borland, S.4    Kori, S.5
  • 19
    • 79955655728 scopus 로고    scopus 로고
    • Orally inhaled dihydroergotamine: Reviving and improving a classic
    • Baron EP, Tepper SJ. Orally inhaled dihydroergotamine: Reviving and improving a classic. Future Neurol. 2011;6: 327-333.
    • (2011) Future Neurol , vol.6 , pp. 327-333
    • Baron, E.P.1    Tepper, S.J.2
  • 21
    • 0037316036 scopus 로고    scopus 로고
    • Ergotamine and dihydroergotamine: History, pharmacology, and efficacy
    • Silberstein SD, McCrory DC. Ergotamine and dihydroergotamine: History, pharmacology, and efficacy. Headache. 2003;43: 144-166.
    • (2003) Headache , vol.43 , pp. 144-166
    • Silberstein, S.D.1    McCrory, D.C.2
  • 22
    • 0029812218 scopus 로고    scopus 로고
    • Human pharmacokinetics of dihydroergotamine administered by nasal spray
    • Humbert H, Cabiac MD, Dubray C, Lavene D. Human pharmacokinetics of dihydroergotamine administered by nasal spray. Clin Pharmacol Ther. 1996;60: 265-275.
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 265-275
    • Humbert, H.1    Cabiac, M.D.2    Dubray, C.3    Lavene, D.4
  • 23
    • 33748325882 scopus 로고    scopus 로고
    • Drugtarget residence time and its implications for lead optimization
    • Copeland RA, Pompliano DL, Meek TD. Drugtarget residence time and its implications for lead optimization. Nat Rev Drug Discov. 2006;5: 730-739.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 730-739
    • Copeland, R.A.1    Pompliano, D.L.2    Meek, T.D.3
  • 24
    • 84893968414 scopus 로고    scopus 로고
    • Sustained pain relief with dihydroergotamine in migraine is potentially due to persistent binding to 5-hr1b and 5-ht1d receptors [poster p7]
    • also presented at 3rd Joint Biennial Congress of European Headache and Migraine Trust International Congress London, United Kingdom Sept. 20-23 2012 (Abstract
    • Kori S, Zhang J, Kellerman D, Armer T, Goadsby PJ. Sustained pain relief with dihydroergotamine in migraine is potentially due to persistent binding to 5-HR1B and 5-HT1D receptors [poster P7]. Headache. 2012;52: 874-875, also presented at 3rd Joint Biennial Congress of European Headache and Migraine Trust International Congress London, United Kingdom Sept. 20-23, 2012 (Abstract).
    • (2012) Headache , vol.52 , pp. 874-875
    • Kori, S.1    Zhang, J.2    Kellerman, D.3    Armer, T.4    Goadsby, P.J.5
  • 25
    • 0025924897 scopus 로고
    • Localization c: 3h-dihydroergota-mine-binding sties in the cat central nervous system: Relevance to migraine
    • Goadsby PJ, Gundlach AL. Localization c: 3H-dihydroergota-mine-binding sties in the cat central nervous system: Relevance to migraine. Ann Neurol. 1991;29: 91-94.
    • (1991) Ann Neurol , vol.29 , pp. 91-94
    • Goadsby, P.J.1    Gundlach, A.L.2
  • 26
    • 79953688704 scopus 로고    scopus 로고
    • Map0004, orally inhaled dhe: A randomized, controlled study in the acute treatment of migraine
    • Aurora SK, Silberstein SD, Kori SH, et al. MAP0004, orally inhaled DHE: A randomized, controlled study in the acute treatment of migraine. Headache. 2011;51: 507-517.
    • (2011) Headache , vol.51 , pp. 507-517
    • Aurora, S.K.1    Silberstein, S.D.2    Kori, S.H.3
  • 27
    • 80053473197 scopus 로고    scopus 로고
    • Map0004, orally inhaled dhe for the acute treatment of migraine: Efficacy of early and late treatments
    • Tepper SJ, Kori SH, Goadsby PJ, et al. MAP0004, orally inhaled DHE for the acute treatment of migraine: Efficacy of early and late treatments. Mayo Clin Proc. 2011;86: 948-955.
    • (2011) Mayo Clin Proc , vol.86 , pp. 948-955
    • Tepper, S.J.1    Kori, S.H.2    Goadsby, P.J.3
  • 28
    • 0347319254 scopus 로고    scopus 로고
    • Defeating migraine pain with triptans: A race against the development of cutaneous allodynia
    • Burstein R, Collins B, Jakubowski M. Defeating migraine pain with triptans: A race against the development of cutaneous allodynia. Ann Neurol. 2004;55: 19-26.
    • (2004) Ann Neurol , vol.55 , pp. 19-26
    • Burstein, R.1    Collins, B.2    Jakubowski, M.3
  • 29
    • 21644437561 scopus 로고    scopus 로고
    • Effects of sensitization of trigeminovascular neurons to triptan therapy during migraine
    • Burstein R, Levy D, Jakubowski M. Effects of sensitization of trigeminovascular neurons to triptan therapy during migraine. Rev Neurol (Paris). 2005; 161: 658-660.
    • (2005) Rev Neurol (Paris , vol.161 , pp. 658-660
    • Burstein, R.1    Levy, D.2    Jakubowski, M.3
  • 30
    • 84856290046 scopus 로고    scopus 로고
    • Efficacy and safety of map0004, orally inhaled dhe in treating migraines with and without allodynia
    • Tepper SJ, Kori SH, Borland SW, et al. Efficacy and safety of MAP0004, orally inhaled DHE in treating migraines with and without allodynia. Headache. 2012;52: 37-47.
    • (2012) Headache , vol.52 , pp. 37-47
    • Tepper, S.J.1    Kori, S.H.2    Borland, S.W.3
  • 31
    • 84891783779 scopus 로고    scopus 로고
    • Headache Classification Committee of the International Headache Society (IHS). 3rd Edition, Beta Version. Cephalalgia
    • Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorder, 3rd Edition, Beta Version. Cephalalgia. 2013;33: 629-808.
    • (2013) The International Classification of Headache Disorder , vol.33 , pp. 629-808
  • 32
    • 65849479472 scopus 로고    scopus 로고
    • Perimenstrual migraines: Are they different than migraines in general?
    • Tepper SJ. Perimenstrual migraines: Are they different than migraines in general? Curr Pain Headache Rep. 2008;12: 463-467.
    • (2008) Curr Pain Headache Rep , vol.12 , pp. 463-467
    • Tepper, S.J.1
  • 33
    • 84893940745 scopus 로고    scopus 로고
    • Analysis of patients with menstrually related migraine vs. Non-menstrually related migraine treated with map0004
    • (Abstract
    • Aurora SK, Lu B, Connors E, Li X, Kellerman D, Kori S. Analysis of patients with menstrually related migraine vs. non-menstrually related migraine treated with MAP0004. J Headache Pain. 2013; 14(Suppl. 1): P143 (Abstract).
    • (2013) J Headache Pain , vol.14 , Issue.SUPPL. 1
    • Aurora, S.K.1    Lu, B.2    Connors, E.3    Li, X.4    Kellerman, D.5    Kori, S.6
  • 34
    • 84893983326 scopus 로고    scopus 로고
    • Map0004 provided consistent migraine pain relief even after repeated administration
    • (Abstract); also presented at PAINWeek meeting, Las Vegas, NV, September 2012 (Abstract
    • Kori S, Lu B, Connors E, Li X, Kellerman D. MAP0004 provided consistent migraine pain relief even after repeated administration. J Headache Pain. 2013;14(Suppl. 1): P190 (Abstract); also presented at PAINWeek meeting, Las Vegas, NV, September 2012 (Abstract).
    • (2013) J Headache Pain , vol.14 , Issue.SUPPL. 1
    • Kori, S.1    Lu, B.2    Connors, E.3    Li, X.4    Kellerman, D.5
  • 35
    • 84893971628 scopus 로고    scopus 로고
    • Consistency of migraine pain relief after repeated administration of map0004
    • (Meeting Abstracts 1) (Abstract
    • Kori S, Lu B, Connors E, Li X, Kellerman D. Consistency of migraine pain relief after repeated administration of MAP0004. Neurology. 2013;80 (Meeting Abstracts 1): P01.086 (Abstract).
    • (2013) Neurology , vol.80
    • Kori, S.1    Lu, B.2    Connors, E.3    Li, X.4    Kellerman, D.5
  • 36
    • 84893952896 scopus 로고    scopus 로고
    • A long-term open-label study assessing the safety and tolerability of map0004 orally inhaled dihydroergotamine in adult migraineurs
    • Palm Springs, CA, February 23-26, (Abstract
    • Kori S, Kellerman D, Chang J, Reppine A. A Long-term Open-label Study assessing the safety and tolerability of MAP0004 orally inhaled dihydroergotamine in adult migraineurs. 28th Annual Meeting of the American Academy of Pain Medicine (AAPM), Palm Springs, CA, February 23-26, 2012 (Abstract).
    • (2012) 28th Annual Meeting of the American Academy of Pain Medicine (AAPM
    • Kori, S.1    Kellerman, D.2    Chang, J.3    Reppine, A.4
  • 37
    • 47949104036 scopus 로고    scopus 로고
    • Randomized double-blind controlled study of the safety tolerability and pharmacokinetics of map0004 (orally-inhaled dhe) in adult asthmatics
    • Shrewsbury SB, Kori SH, Miller SD, Pedinoff A, Weinstein S. Randomized double-blind controlled study of the safety, tolerability, and pharmacokinetics of MAP0004 (orally-inhaled DHE) in adult asthmatics. Curr Med Res Opin. 2008;24: 1977-1985.
    • (2008) Curr Med Res Opin , vol.24 , pp. 1977-1985
    • Shrewsbury, S.B.1    Kori, S.H.2    Miller, S.D.3    Pedinoff, A.4    Weinstein, S.5
  • 38
    • 84893945537 scopus 로고    scopus 로고
    • Acute inhalation safety of map0004: Studies in healthy volunteers, smokers, and patients with asthma [poster p6]
    • (Abstract
    • Chang J, Kellerman D, Kori S, Meyer J, Zhou J, Armer T. Acute inhalation safety of MAP0004: Studies in healthy volunteers, smokers, and patients with asthma [poster P6]. Headache. 2012;52: 874 (Abstract).
    • (2012) Headache , vol.52 , pp. 874
    • Chang, J.1    Kellerman, D.2    Kori, S.3    Meyer, J.4    Zhou, J.5    Armer, T.6
  • 39
    • 84893967358 scopus 로고    scopus 로고
    • A thorough qt study comparing supratherapeutic dose of orally inhaled dhe, moxifloxacin, and placebo on the qt interval in healthy volunteers
    • (Abstract
    • Jividen H, Haugen G,Kellerman D,Kori S, Heyman E, Elhard M. A thorough QT study comparing supratherapeutic dose of orally inhaled DHE, moxifloxacin, and placebo on the QT interval in healthy volunteers. Headache. 2011;51(S1): 21-22 (Abstract).
    • (2011) Headache , vol.51 , Issue.S1 , pp. 21-22
    • Jividen, H.1    Haugen, G.2    Kellerman, D.3    Kori, S.4    Heyman, E.5    Elhard, M.6
  • 43
    • 84893959175 scopus 로고    scopus 로고
    • Cited in abstracts and citations
    • Humphrey P. Cited in abstracts and citations. Headache. 2007;47: 940.
    • (2007) Headache , vol.47 , pp. 940
    • Humphrey, P.1


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