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Volumn 33, Issue 2, 2014, Pages 165-173

Tofacitinib for acute rheumatoid arthritis patients who have had an inadequate response to disease-modifying antirheumatic drug (DMARD): A systematic review and meta-analysis

Author keywords

Rheumatoid treatment outcome meta analysis; Tofacitinib arthritis

Indexed keywords

ACUTE DISEASE; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; BIOLOGICAL PRODUCTS; FEMALE; HUMANS; MALE; PIPERIDINES; PROTEIN KINASE INHIBITORS; PYRIMIDINES; PYRROLES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REMISSION INDUCTION; TREATMENT OUTCOME;

EID: 84893936361     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-013-2452-7     Document Type: Review
Times cited : (10)

References (23)
  • 1
    • 84893964269 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration (FDA) Accessed 1 Aug 2013
    • U.S. Food and Drug Administration (FDA). Available at: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm327152.htm. Accessed 1 Aug 2013
  • 2
    • 84893960211 scopus 로고    scopus 로고
    • American College of Rheumatology Accessed 1 Aug 2013
    • American College of Rheumatology. Available at: http://www.rheumatology. org/Publications/Hotline/Tofacitinib-for-the-Treatment-of-Rheumatoid-Arthritis/. Accessed 1 Aug 2013
  • 4
    • 70049099036 scopus 로고    scopus 로고
    • Assessing risk of bias in included studies
    • Chapter 8 Higgins JPT, Green S (editors) Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011
    • Higgins JPT AD, Sterne JAC (eds) (2011) Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org
    • (2011) Cochrane Handbook for Systematic Reviews of Interventions
    • Higgins Jpt, A.D.1    Jac, S.2
  • 5
    • 84890659505 scopus 로고    scopus 로고
    • Chapter 12: Interpreting results and drawing conclusions
    • Higgins JPT, Green S (editors) Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011
    • Schünemann HJ OA, Vist GE, Higgins JPT, Deeks JJ, Glasziou P, Guyatt GH (2011) Chapter 12: Interpreting results and drawing conclusions. In: Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011 Available from www.cochrane-handbook.org
    • (2011) Cochrane Handbook for Systematic Reviews of Interventions
    • Schünemann Hj Oa, V.1
  • 6
    • 84873707288 scopus 로고    scopus 로고
    • Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: A randomised phase 3 trial
    • 10.1016/S0140-6736(12)61424-X 10.1016/S0140-6736(12)61424-X
    • Burmester GR, Blanco R, Charles-Schoeman C, Wollenhaupt J, Zerbini C, Benda B, Gruben D, Wallenstein G, Krishnaswami S, Zwillich SH, Koncz T, Soma K, Bradley J, Mebus C (2013) Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial. Lancet 9865:451-460. doi: 10.1016/S0140-6736(12)61424-X
    • (2013) Lancet , vol.9865 , pp. 451-460
    • Burmester, G.R.1    Blanco, R.2    Charles-Schoeman, C.3    Wollenhaupt, J.4    Zerbini, C.5    Benda, B.6    Gruben, D.7    Wallenstein, G.8    Krishnaswami, S.9    Zwillich, S.H.10    Koncz, T.11    Soma, K.12    Bradley, J.13    Mebus, C.14
  • 9
    • 84866156845 scopus 로고    scopus 로고
    • A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone
    • 10.1002/art.33419 10.1002/art.33419
    • Kremer JM, Cohen S, Wilkinson BE, Connell CA, French JL, Gomez-Reino J, Gruben D, Kanik KS, Krishnaswami S, Pascual-Ramos V, Wallenstein G, Zwillich SH (2012) A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone. Arthritis Rheum 4:970-981. doi: 10.1002/art.33419
    • (2012) Arthritis Rheum , vol.4 , pp. 970-981
    • Kremer, J.M.1    Cohen, S.2    Wilkinson, B.E.3    Connell, C.A.4    French, J.L.5    Gomez-Reino, J.6    Gruben, D.7    Kanik, K.S.8    Krishnaswami, S.9    Pascual-Ramos, V.10    Wallenstein, G.11    Zwillich, S.H.12
  • 10
    • 84893929976 scopus 로고    scopus 로고
    • ClinicalTrials.gov Accessed 1 Aug 2013
    • ClinicalTrials.gov. Available at: http://clinicaltrials.gov/ct2/show/ NCT00856544?term=NCT00856544&rank=1. Accessed 1 Aug 2013
  • 11
    • 84860388892 scopus 로고    scopus 로고
    • Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate
    • 10.1002/acr.20494 10.1002/acr.20494
    • Tanaka Y, Suzuki M, Nakamura H, Toyoizumi S, Zwillich SH (2011) Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate. Arthritis Care Res 8:1150-1158. doi: 10.1002/acr.20494
    • (2011) Arthritis Care Res , vol.8 , pp. 1150-1158
    • Tanaka, Y.1    Suzuki, M.2    Nakamura, H.3    Toyoizumi, S.4    Zwillich, S.H.5
  • 12
    • 67650093218 scopus 로고    scopus 로고
    • The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo
    • 10.1002/art.24567
    • Kremer JM, Bloom BJ, Breedveld FC, Coombs JH, Fletcher MP, Gruben D, Krishnaswami S, Burgos-Vargas R, Wilkinson B, Zerbini CA, Zwillich SH (2009) The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo. Arthritis Rheum 7:1895-1905
    • (2009) Arthritis Rheum , vol.7 , pp. 1895-1905
    • Kremer, J.M.1    Bloom, B.J.2    Breedveld, F.C.3    Coombs, J.H.4    Fletcher, M.P.5    Gruben, D.6    Krishnaswami, S.7    Burgos-Vargas, R.8    Wilkinson, B.9    Zerbini, C.A.10    Zwillich, S.H.11
  • 13
    • 84893908680 scopus 로고    scopus 로고
    • ClinicalTrials.gov Accessed 1 Aug 2013
    • ClinicalTrials.gov. Available at: http://clinicaltrials.gov/ct2/show/ NCT00687193?term=NCT00687193&rank=1. Accessed 1 Aug 2013
  • 14
    • 84857761516 scopus 로고    scopus 로고
    • Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs
    • 10.1002/art.33383 10.1002/art.33383
    • Fleischmann R, Cutolo M, Genovese MC, Lee EB, Kanik KS, Sadis S, Connell CA, Gruben D, Krishnaswami S, Wallenstein G, Wilkinson BE, Zwillich SH (2012) Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs. Arthritis Rheum 3:617-629. doi: 10.1002/art.33383
    • (2012) Arthritis Rheum , vol.3 , pp. 617-629
    • Fleischmann, R.1    Cutolo, M.2    Genovese, M.C.3    Lee, E.B.4    Kanik, K.S.5    Sadis, S.6    Connell, C.A.7    Gruben, D.8    Krishnaswami, S.9    Wallenstein, G.10    Wilkinson, B.E.11    Zwillich, S.H.12
  • 16
    • 75749127860 scopus 로고    scopus 로고
    • Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: Results from a randomised, double-blind, placebo-controlled trial
    • 10.1136/ard.2009.108159 10.1136/ard.2009.108159
    • Coombs JH, Bloom BJ, Breedveld FC, Fletcher MP, Gruben D, Kremer JM, Burgos-Vargas R, Wilkinson B, Zerbini CA, Zwillich SH (2010) Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: results from a randomised, double-blind, placebo-controlled trial. Ann Rheum Dis 2:413-416. doi: 10.1136/ard.2009.108159
    • (2010) Ann Rheum Dis , vol.2 , pp. 413-416
    • Coombs, J.H.1    Bloom, B.J.2    Breedveld, F.C.3    Fletcher, M.P.4    Gruben, D.5    Kremer, J.M.6    Burgos-Vargas, R.7    Wilkinson, B.8    Zerbini, C.A.9    Zwillich, S.H.10
  • 17
    • 84893978243 scopus 로고    scopus 로고
    • ClinicalTrials.gov Accessed 1 Aug 2013
    • ClinicalTrials.gov. Available at: http://clinicaltrials.gov/show/ NCT01164579. Accessed 1 Aug 2013
  • 18
    • 84893960506 scopus 로고    scopus 로고
    • WHO International Clinical Trial Registration Platform (ICTRP) Accessed 1 Aug 2013
    • WHO International Clinical Trial Registration Platform (ICTRP). Available at: http://apps.who.int/trialsearch/Trial.aspx?TrialID=EUCTR2009-016987-34-PL. Accessed 1 Aug 2013
  • 19
    • 84893906242 scopus 로고    scopus 로고
    • WHO International Clinical Trial Registration Platform (ICTRP) Accessed 1 Aug 2013
    • WHO International Clinical Trial Registration Platform (ICTRP). Available at: http://apps.who.int/trialsearch/Trial.aspx?TrialID=EUCTR2010-020890-18-CZ. Accessed 1 Aug 2013
  • 20
    • 84893951904 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration (FDA) Accessed 1 Aug 2013
    • U.S. Food and Drug Administration (FDA). Available at: http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/ Drugs/ArthritisAdvisoryCommittee/UCM304199.pdf. Accessed 1 Aug 2013
  • 23
    • 84878936389 scopus 로고    scopus 로고
    • Meta-analysis of malignancies, serious infections, and serious adverse events with tofacitinib or biologic treatment in rheumatoid arthritis clinical trials
    • Ahadieh S, Checchio T, Tensfeldt T, French J, Krishnaswami S, Riese R, Menon S, Boy MG, Geier JL (2012) Meta-analysis of malignancies, serious infections, and serious adverse events with tofacitinib or biologic treatment in rheumatoid arthritis clinical trials. Arthritis Rheum 64:S726
    • (2012) Arthritis Rheum , vol.64 , pp. 726
    • Ahadieh, S.1    Checchio, T.2    Tensfeldt, T.3    French, J.4    Krishnaswami, S.5    Riese, R.6    Menon, S.7    Boy, M.G.8    Geier, J.L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.