Systematic RH genotyping and variant identification in French donors of African origin

Blood Transfusion

Volumn 12, Issue SUPPL.1, 2014, Pages

  Kappler Gratias, Sandrine ^a   Auxerre, Carine ^a   Dubeaux, Isabelle ^a   Beolet, Marylise ^b   Ripaux, Maryline ^a   Le Pennec, Pierre Yves ^a   Pham, Bach Nga ^a  

^a INSTITUT NATIONAL DE LA TRANSFUSION SANGUINE   (France)

^b French Blood Institute   (France)

Author keywords

Blood donors; DNA testing; Molecular analysis; Rh blood group system; Rh variants

Indexed keywords

AFRICA; AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; FEMALE; FRANCE; GENE FREQUENCY; GENETIC LINKAGE; GENOTYPING TECHNIQUES; HAPLOTYPES; HUMANS; MALE; PHENOTYPE; RH-HR BLOOD-GROUP SYSTEM;

EID: 84893903012     PISSN: 17232007     EISSN: None     Source Type: Journal    
DOI: 10.2450/2013.0270-12     Document Type: Article

References (32)

1. Daniels G, Poole J, de Silva M, et al. The clinical significance of blood group antibodies. Transfus Med 2002; 12: 287-95.
2. Daniels G, Castilho L, Flegel WA, et al. International Society of Blood Transfusion Committee on terminology for red blood cell surface antigens: Macao report. Vox Sang 2009; 96: 153-6.
3. Cherif-Zahar B, Le Van Kim C, Rouillac C, et al. Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region. Genomics 1994; 19: 68-74.
4. Mouro I, Colin Y, Cherif-Zahar B, et al. Molecular genetic basis of the human Rhesus blood group system. Nat Genet 1993; 5: 62-5.
5. Cherif-Zahar B, Mattei MG, Le Van Kim C, et al. Localization of the human Rh blood group gene structure to chromosome region 1p34.3-1p36.1 by in situ hybridization. Hum Genet 1991; 86: 398-400.
6. Colin Y, Cherif-Zahar B, Le Van Kim C, et al. Recent advances in molecular and genetic analysis of Rh blood group structures. J Med Primatol 1993; 22: 36-43.
7. Colin Y, Cherif-Zahar B, Le Van Kim C, et al. Genetic basis of the RhD-positive and RhD-negative blood group polymorphism as determined by Southern analysis. Blood 1991; 78: 2747-52.
8. Flegel WA. Molecular genetics of RH and its clinical application. Transfus Clin Biol 2006; 13: 4-12.
9. Wagner FF, Flegel WA. Review: the molecular basis of the Rh blood group phenotypes. Immunohematology 2004; 20: 23-36.
10. Westhoff CM. The structure and function of the Rh antigen complex. Semin Hematol 2007; 44: 42-50.
11. Avent ND, Reid ME. The Rh blood group system: a review. Blood 2000; 95: 375-87.
12. Stratton F. A new Rh allelomorph. Nature 1946; 158: 25.
13. Silvy M, Chapel-Fernandes S, Callebaut I, et al. Characterization of novel RHD alleles: relationship between phenotype, genotype, and trimeric architecture. Transfusion 2012; 52: 2020-9.
14. Flegel WA, Wagner FF. Molecular biology of partial D and weak D: implications for blood bank practice. Clin Lab 2002; 48: 53-9.
15. Wagner FF, Moulds JM, Tounkara A, et al. RHD allele distribution in Africans of Mali. BMC Genet 2003; 4: 14.
16. Daniels G. The molecular genetics of blood group polymorphism. Hum Genet 2009; 126: 729-42.
17. Rouillac C, Gane P, Cartron J, et al. Molecular basis of the altered antigenic expression of RhD in weak D(Du) and RhC/e in RN phenotypes. Blood 1996; 87: 4853-61.
18. Faas BH, Beckers EA, Wildoer P, et al. Molecular background of VS and weak C expression in blacks. Transfusion 1997; 37: 38-44.
19. Daniels GL, Faas BH, Green CA, et al. The VS and V blood group polymorphisms in Africans: a serologic and molecular analysis. Transfusion 1998; 38: 951-8.
20. Westhoff CM, Vege S, Halter-Hipsky C, et al. DIIIa and DIII Type 5 are encoded by the same allele and are associated with altered RHCEce alleles: clinical implications. Transfusion 2010; 50: 1303-11.
21. Pham BN, Peyrard T, Juszczak G, et al. Analysis of RhCE variants among 806 individuals in France: considerations for transfusion safety, with emphasis on patients with sickle cell disease. Transfusion 2011; 51: 1249-60.
22. Hemker MB, Ligthart PC, Berger L, et al. DAR, a new RhD variant involving exons 4, 5, and 7, often in linkage with ceAR, a new Rhce variant frequently found in African blacks. Blood 1999; 94: 4337-42.
23. Peyrard T, Pham BN, Poupel S, et al. Alloanti-c/ce in a c+ceAR/Ce patient suggests that the rare RHCE ceAR allele (ceAR) encodes a partial c antigen. Transfusion 2009; 49: 2406-11.
24. Hipsky CH, Lomas-Francis C, Fuchisawa A, Reid ME.RHCE ceAR encodes a partial c (RH4) antigen. Immunohematology 2010; 26: 57-9.
25. Noizat-Pirenne F, Mouro I, Le Pennec PY, et al. Two new alleles of the RHCE gene in Black individuals: the RHce allele ceMO and the RHcE allele cEMI. Br J Haematol 2001; 113: 672-9.
26. Legler TJ, Maas JH, Kohler M, et al. RHD sequencing: a new tool for decision making on transfusion therapy and provision of Rh prophylaxis. Transfus Med 2001; 11: 383-8.
27. Noizat-Pirenne F, Lee K, Pennec PY, et al. Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety. Blood 2002; 100: 4223-31.
28. Howes RE, Patil AP, Piel FB, et al. The global distribution of the Duffy blood group. Nat Commun 2011; 2: 266.
29. Reid ME, Lomas-Francis C. The blood group antigen factsbook. 2nd ed. San Diego, CA, London: Academic; 2004.
30. Singleton BK, Green CA, Avent ND, et al. The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in Africans with the Rh D-negative blood group phenotype. Blood 2000; 95: 12-8.
31. Peyrard T, Pham BN, Le Pennec PY, Rouger P. The rare blood groups: a public health challenge. Transfus Clin Biol 2008; 15: 109-19.
32. Tregellas WM, Issitt PD. An investigation of the relationship between the V(hrv), VS, and hrH antigens. Transfusion 1978; 18: 15-20.