Efficacy of intra-arterial therapy in the elderly requires further study

Journal of NeuroInterventional Surgery

Volumn 8, Issue E1, 2016, Pages e6-e7

  Hirsch, Joshua A ^a   Mehta, Brijesh P ^a   Chandra, Ronil V ^a   Leslie Mazwi, Thabele M ^a   Rost, Natalia S ^a   Yoo, Albert J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLASMINOGEN ACTIVATOR;

AGED; ALL CAUSE MORTALITY; BLOOD VESSEL RUPTURE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; DISEASE MANAGEMENT; DRUG SAFETY; HIGH RISK PATIENT; HUMAN; INTERMETHOD COMPARISON; INTRAARTERIAL DRUG ADMINISTRATION; LETTER; NATIONAL INSTITUTES OF HEALTH STROKE SCALE SCORE; PRIORITY JOURNAL; RANKIN SCALE; RECANALIZATION; REVASCULARIZATION; SCORING SYSTEM;

EID: 84893874328     PISSN: 17598478     EISSN: 17598486     Source Type: Journal    
DOI: 10.1136/neurintsurg-2012-010524     Document Type: Letter

References (10)

1. Ghobrial GM, Chalouhi N, Rivers L, et al. Multimodal endovascular management of acute ischemic stroke in patients over 75 years old is safe and effective. J Neurointerv Surg 2013;5:i33-7.
2. Hirsch JA, Yoo AJ, Nogueira RG, et al. Case volumes of intra-arterial and intravenous treatment of ischemic stroke in the USA. J Neurointerv Surg 2009;1:27-31.
3. Chandra RV, Leslie-Mazwi TM, Oh DC, et al. Elderly patients are at higher risk for poor outcomes after intra-arterial therapy. Stroke 2012;43:2356-61.
4. Mono M-L, Romagna L, Jung S, et al. Intra-arterial thrombolysis for acute ischemic stroke in octogenarians. Cerebrovasc Dis 2012;33:116-22.
5. Qureshi AI, Suri MFK, Georgiadis AL, et al. Intra-arterial recanalization techniques for patients 80 years or older with acute ischemic stroke: pooled analysis from 4 prospective studies. AJNR Am J Neuroradiol 2009;30:1184-9.
6. Loh Y, Kim D, Shi ZS, et al. Higher rates of mortality but not morbidity follow intracranial mechanical thrombectomy in the elderly. AJNR Am J Neuroradiol 2010;31:1181-5.
7. Kim D, Ford GA, Kidwell CS, et al. Intra-arterial thrombolysis for acute stroke in patients 80 and older: a comparison of results in patients younger than 80 years. AJNR Am J Neuroradiol 2007;28:159-63.
8. Flint AC, Duckwiler GR, Budzik RF, et al., for the MERCI and Multi MERCI Writing Committee. Mechanical thrombectomy of intracranial internal carotid occlusion: pooled results of the MERCI and multi MERCI Part I trials. Stroke 2007;38:1274-80.
9. Busl KM, Nogueira RG, Yoo AJ, et al. Prestroke dementia is associated with poor outcomes after reperfusion therapy among elderly stroke patients. J Stroke Cerebrovasc Dis Published Online First: 17 December 2011. doi:10.1016/j. jstrokecerebrovasdis.2011.11.005.
10. Rost NS, Smith EE, Nogueira RG, et al. Implementation of a patient selection protocol for intra-arterial therapy increases treatment rates in patients with acute ischemic stroke. J Neurointerv Surg 2013;5:i44-7.