New fluoranthene FLUN-550 as a fluorescent probe for selective staining and quantification of intracellular lipid droplets

Organic Letters

Volumn 16, Issue 3, 2014, Pages 756-759

  Goel, Atul ^a,b   Sharma, Ashutosh ^a   Kathuria, Manoj ^a   Bhattacharjee, Arindam ^a   Verma, Ashwni ^a   Mishra, Prabhat R ^a   Nazir, Aamir ^a   Mitra, Kalyan ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTOZOAL AGENT; FLUORANTHENE; FLUORENE DERIVATIVE; FLUORESCENT DYE; LIPID; POLYCYCLIC HYDROCARBON;

ANIMAL; ARTICLE; CAENORHABDITIS ELEGANS; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; MACROPHAGE; METABOLISM; PARASITOLOGY; STAINING; TUMOR CELL LINE;

ANIMALS; ANTIPROTOZOAL AGENTS; CAENORHABDITIS ELEGANS; CELL LINE, TUMOR; FLUORENES; FLUORESCENT DYES; HUMANS; LIPIDS; MACROPHAGES; MOLECULAR STRUCTURE; POLYCYCLIC COMPOUNDS; STAINING AND LABELING;

EID: 84893866210     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol403470d     Document Type: Article

References (26)

1. Neef, A. B.; Schultz, C. Angew. Chem., Int. Ed. 2009, 48, 1498
2. Evans, M. J.; Saghatelian, A.; Sorensen, E. J.; Cravatt, B. F. Nat. Biotechnol. 2005, 23, 1303
3. Bachovchin, D. A.; Brown, S. J.; Rosen, H.; Cravatt, B. F. Nat. Biotechnol. 2009, 27, 387
4. Damayanti, N. P.; Parker, L. L.; Irudayaraj, J. M. K. Angew. Chem., Int. Ed. 2013, 52, 3931
5. Greenspan, P.; Fowler, S. D. J. Lipid Res. 1985, 26, 781
6. P. Greenspan, P.; Mayer, E. P.; Fowler, S. D. J. Cell Biol. 1985, 100, 965
7. Listenberger, L. L.; Brown, D. A. Fluorescent Detection of Lipid Droplets and Associated Proteins. In Current Protocols in Cell Biology; Wiley: New York, 2007; Chapter 35, Unit 24.2.
8. Spandl, J.; White, D. J.; Peychl, J.; Thiele, C. Traffic 2009, 10, 1579
9. Lee, J. H.; So, J.-H.; Jeon, J. H.; Choi, E. B.; Lee, Y.-R.; Chang, Y.-T.; Kim, C.-H.; Bae, M. A.; Ahn, J. H. Chem. Commun. 2011, 47, 7500
10. Yang, H. J.; Hsu, C. L.; Yang, J. Y.; Yang, W. Y. PLoS One 2012, 7, e32693
11. Kim, E.; Lee, S.; Park, S. B. Chem. Commun. 2012, 48, 2331
12. Cosgrave, L.; Devocelle, M.; Forster, R. J.; Keyes, T. E. Chem. Commun. 2010, 46, 103
13. Su, X.; Liptak, M. D.; Aprahamian, I. Chem. Commun. 2013, 49, 4160
14. Martin, A.; Long, C.; Forsetr, R. J.; Keyes, T. E. Chem. Commun. 2012, 48, 5617
15. Goel, A.; Sharma, A.; Mitra, K.; Kathuria, M.; Bhattacharjee, A. Indian Patent Appl. No. 807DEL2013, Mar 19, 2013.
16. Goel, A.; Dixit, M.; Chaurasia, S.; Kumar, A.; Raghunandan, R.; Maulik, P. R.; Anand, R. S. Org. Lett. 2008, 10, 2553
17. Goel, A.; Chaurasia, S.; Dixit, M.; Kumar, V.; Prakash, S.; Jena, B.; Verma, J. K.; Jain, M.; Anand, R. S.; Manoharan, S. S. Org. Lett. 2009, 11, 1289
18. Goel, A.; Chaurasia, S.; Kumar, V.; Anand, R. S.; Manoharan, S. WO/2009/122445, Oct 8, 2009.
19. Goel, A.; Chaurasia, S.; Kumar, V.; Anand, R. S.; Manoharan, S. PCT/IN/2009/000215, Mar 31, 2009.
20. Goel, A.; Kumar, V.; Nag, P.; Bajpai, V.; Kumar, B.; Singh, C.; Prakash, S.; Anand, R. S. J. Org. Chem. 2011, 76, 7474
21. Goel, A.; Kumar, V.; Singh, S. P.; Sharma, A.; Prakash, S.; Singh, C.; Anand, R. S. J. Mater. Chem. 2012, 22, 14880
22. Goel, A.; Kumar, V.; Chaurasia, S.; Rawat, M.; Prasad, R.; Anand, R. S. J. Org. Chem. 2010, 75, 3656
23. Weibel, G. L.; Joshi, M. R.; Jerome, W. G.; Bates, S. R.; Yu, K. J.; Phillips, M. C.; Rothbalt, G. H. Biochim. Biophys. Acta 2012, 1821, 464
24. Wolfbauer, G.; Glick, J. M.; Minor, L. K.; Rothblat, G. H. Proc. Natl. Acad. Sci. U.S.A. 1986, 101, 7760
25. Rakotomanga, M.; Blanc, S.; Gaudin, K.; Chaminade, P.; Loiseau, P. M. Antimicrob. Agents Chemother. 2007, 51, 1425
26. Croft, S. L.; Yardley, V. Curr. Pharm. Des. 2002, 8, 319