Vaccination: Intramuscular therapeutic vaccination targeting HPV16 induces T cell responses that localize in mucosal lesions

Science Translational Medicine

Volumn 6, Issue 221, 2014, Pages

  Maldonado, Leonel ^a   Teague, Jessica E ^b   Morrow, Matthew P ^c   Jotova, Iveta ^d   Wu, T C ^a   Wang, Chenguang ^a   Desmarais, Cindy ^e   Boyer, Jean D ^f   Tycko, Benjamin ^d   Robins, Harlan S ^g   Clark, Rachael A ^b   Trimble, Cornelia L ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c Inovio Pharmaceuticals Inc   (United States)

^d New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^e ADAPTIVE BIOTECHNOLOGIES   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; E6 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 16; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOGENE PROTEIN E7, HUMAN PAPILLOMAVIRUS TYPE 16; ONCOPROTEIN; PROTEIN E7; REPRESSOR PROTEIN; VIRUS ANTIGEN; VIRUS VACCINE;

AMINO ACID SEQUENCE; ARTICLE; BLOOD; CD8+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CHEMISTRY; COHORT ANALYSIS; FEMALE; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; IMMUNIZATION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; INTRAMUSCULAR DRUG ADMINISTRATION; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; METABOLISM; MOLECULAR GENETICS; MUCOSAL IMMUNITY; PATHOLOGY; PHASE 1 CLINICAL TRIAL; STROMA CELL; UTERINE CERVIX; UTERINE CERVIX CARCINOMA IN SITU; VACCINATION; VIROLOGY;

AMINO ACID SEQUENCE; ANTIGENS, VIRAL; CANCER VACCINES; CD8-POSITIVE T-LYMPHOCYTES; CELL COMPARTMENTATION; CERVICAL INTRAEPITHELIAL NEOPLASIA; CERVIX UTERI; COHORT STUDIES; FEMALE; HUMAN PAPILLOMAVIRUS 16; HUMANS; IMMUNITY, MUCOSAL; IMMUNIZATION, SECONDARY; IMMUNOLOGIC MEMORY; INJECTIONS, INTRAMUSCULAR; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; MOLECULAR SEQUENCE DATA; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS E7 PROTEINS; RECEPTORS, ANTIGEN, T-CELL; REPRESSOR PROTEINS; STROMAL CELLS; VACCINATION; VIRAL VACCINES;

EID: 84893856633     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3007323     Document Type: Article

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