메뉴 건너뛰기




Volumn 74, Issue 3, 2014, Pages 686-694

Monitoring chemotherapeutic response by hyperpolarized 13C-fumarate MRS and diffusion MRI

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ANTINEOPLASTIC AGENTS; CARBON ISOTOPES; CELL LINE, TUMOR; DIFFUSION MAGNETIC RESONANCE IMAGING; DISEASE MODELS, ANIMAL; FEMALE; FUMARATES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; NEOPLASMS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84893837433     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1914     Document Type: Article
Times cited : (44)

References (50)
  • 1
    • 77954235111 scopus 로고    scopus 로고
    • Targeting the mitogen-activated protein kinase pathway: Physiological feedback and drug response
    • Pratilas CA, Solit DB. Targeting the mitogen-activated protein kinase pathway: physiological feedback and drug response. Clin Cancer Res 2010;16:3329-34.
    • (2010) Clin Cancer Res , vol.16 , pp. 3329-3334
    • Pratilas, C.A.1    Solit, D.B.2
  • 2
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    • Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004; 64:7099-7109.
    • (2004) Cancer Res , vol.64 , pp. 7099-7109
    • Wilhelm, S.M.1    Carter, C.2    Tang, L.3    Wilkie, D.4    McNabola, A.5    Rong, H.6
  • 7
    • 80051479922 scopus 로고    scopus 로고
    • Rationale and design of decision: A double-blind, randomized, placebo-controlled phase III trial evaluating the efficacy and safety of sorafenib in patients with locally advanced or metastatic radioactive iodine (RAI)-refractory, differentiated thyroid cancer
    • Brose MS, Nutting CM, Sherman SI, Shong YK, Smit JWA, Reike G, et al. Rationale and design of decision: a double-blind, randomized, placebo-controlled phase III trial evaluating the efficacy and safety of sorafenib in patients with locally advanced or metastatic radioactive iodine (RAI)-refractory, differentiated thyroid cancer. BMC Cancer 2011;11:349.
    • (2011) BMC Cancer , vol.11 , pp. 349
    • Brose, M.S.1    Nutting, C.M.2    Sherman, S.I.3    Shong, Y.K.4    Smit, J.W.A.5    Reike, G.6
  • 9
    • 84857073184 scopus 로고    scopus 로고
    • Randomized phase II trial of sorafenib with temsirolimus or Tipifarnib in untreated metastatic melanoma (S0438)
    • Margolin KA, Moon J, Flaherty LE, Lao CD, Akerley WL III, Othus M, et al. Randomized phase II trial of sorafenib with temsirolimus or Tipifarnib in untreated metastatic melanoma (S0438). Clin Cancer Res 2012;18:1129-37.
    • (2012) Clin Cancer Res , vol.18 , pp. 1129-1137
    • Margolin, K.A.1    Moon, J.2    Flaherty, L.E.3    Lao, C.D.4    Akerley III, W.L.5    Othus, M.6
  • 10
    • 84857427678 scopus 로고    scopus 로고
    • Sorafenib for patients with advanced angiosarcoma: A phase II trial from the French Sarcoma Group (GSF/GETO)
    • Ray-Coquard I, Italiano A, Bompas E, Le Cesne A, Robin Y-M, Chevreau C, et al. Sorafenib for patients with advanced angiosarcoma: a phase II trial from the French Sarcoma Group (GSF/GETO). Oncologist 2012;17:260-6.
    • (2012) Oncologist , vol.17 , pp. 260-266
    • Ray-Coquard, I.1    Italiano, A.2    Bompas, E.3    Le Cesne, A.4    Robin, Y.-M.5    Chevreau, C.6
  • 11
    • 77954754601 scopus 로고    scopus 로고
    • Phase II evaluation of sorafenib in advanced and metastatic squamous cell carcinoma of the head and neck: Southwest Oncology Group Study S0420
    • Williamson SK, Moon J, Huang CH, Guaglianone PP, LeBlanc M, Wolf GT, et al. Phase II evaluation of sorafenib in advanced and metastatic squamous cell carcinoma of the head and neck: Southwest Oncology Group Study S0420. J Clin Oncol 2010;28:3330-35.
    • (2010) J Clin Oncol , vol.28 , pp. 3330-3335
    • Williamson, S.K.1    Moon, J.2    Huang, C.H.3    Guaglianone, P.P.4    Leblanc, M.5    Wolf, G.T.6
  • 13
    • 84856233838 scopus 로고    scopus 로고
    • Phase IISWOG-directed intergroup trial (S0505) of sorafenib in advanced soft tissue sarcomas
    • von Mehren M, Rankin C, GoldblumJR, Demetri GD, Bramwell V, Ryan CW, et al. Phase IISWOG-directed intergroup trial (S0505) of sorafenib in advanced soft tissue sarcomas. Cancer 2012;118:770-6.
    • (2012) Cancer , vol.118 , pp. 770-776
    • Von Mehren, M.1    Rankin, C.2    Goldblum, J.R.3    Demetri, G.D.4    Bramwell, V.5    Ryan, C.W.6
  • 14
    • 34249874331 scopus 로고    scopus 로고
    • Diffusion-weighted MRI in the body: Applications and challenges in oncology
    • Koh D-M, Collins DJ. Diffusion-weighted MRI in the body: applications and challenges in oncology. AJRAmJ Roentgenol 2007;188:1622-35.
    • (2007) AJRAmJ Roentgenol , vol.188 , pp. 1622-1635
    • Koh, D.-M.1    Collins, D.J.2
  • 15
    • 34848889581 scopus 로고    scopus 로고
    • MRI-measured water mobility increases in response to chemotherapy via multiple cell-death mechanisms
    • Morse DL, Galons J-P, Payne CM, Jennings DL, Day S, Xia G, et al. MRI-measured water mobility increases in response to chemotherapy via multiple cell-death mechanisms. NMR Biomed 2007;20:602-14.
    • (2007) NMR Biomed , vol.20 , pp. 602-614
    • Morse, D.L.1    Galons, J.-P.2    Payne, C.M.3    Jennings, D.L.4    Day, S.5    Xia, G.6
  • 16
    • 34748865456 scopus 로고    scopus 로고
    • Diffusion magnetic resonance imaging: A biomarker for treatment response in oncology
    • Hamstra DA, Rehemtulla A, Ross BD. Diffusion magnetic resonance imaging: a biomarker for treatment response in oncology. J Clin Oncol 2007;25:4104-109.
    • (2007) J Clin Oncol , vol.25 , pp. 4104-4109
    • Hamstra, D.A.1    Rehemtulla, A.2    Ross, B.D.3
  • 17
    • 0034119889 scopus 로고    scopus 로고
    • Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging
    • Lyng H, Haraldseth O, Rofstad EK. Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging. Magnetic Resonance in Medicine 2000; 43:828-36.
    • (2000) Magnetic Resonance in Medicine , vol.43 , pp. 828-836
    • Lyng, H.1    Haraldseth, O.2    Rofstad, E.K.3
  • 18
    • 84873993074 scopus 로고    scopus 로고
    • Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells
    • Lodi A, Woods SM, Ronen SM. Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells. NMR Biomed. 2013;26: 299-306
    • (2013) NMR Biomed. , vol.26 , pp. 299-306
    • Lodi, A.1    Woods, S.M.2    Ronen, S.M.3
  • 19
  • 21
    • 79960886776 scopus 로고    scopus 로고
    • Hyperpolarized [1-13C]-ascorbic and dehydroascorbic acid: Vitamin C as a probe for imaging redox status in vivo
    • Bohndiek SE, Kettunen MI, Hu D, Kennedy BWC, Boren J, Gallagher FA, et al. Hyperpolarized [1-13C]-ascorbic and dehydroascorbic acid: vitamin C as a probe for imaging redox status in vivo. J Am Chem Soc 2011;133:11795-801.
    • (2011) J Am Chem Soc , vol.133 , pp. 11795-11801
    • Bohndiek, S.E.1    Kettunen, M.I.2    Hu, D.3    Kennedy, B.W.C.4    Boren, J.5    Gallagher, F.A.6
  • 22
  • 23
    • 79951507755 scopus 로고    scopus 로고
    • Analysis of cancer metabolism by imaging hyperpolarized nuclei: Prospects for translation to clinical research
    • Kurhanewicz J, Vigneron DB, Brindle K, Chekmenev EY, Comment A, Cunningham CH, et al. Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research. Neoplasia 2011;13:81-97.
    • (2011) Neoplasia , vol.13 , pp. 81-97
    • Kurhanewicz, J.1    Vigneron, D.B.2    Brindle, K.3    Chekmenev, E.Y.4    Comment, A.5    Cunningham, C.H.6
  • 25
    • 73949133557 scopus 로고    scopus 로고
    • Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors
    • Gallagher FA, Kettunen MI, Hu D-E, Jensen PR, Zandt RI, Karlsson M, et al. Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors. Proc Natl Acad Sci U S A 2009;106:19801-6.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 19801-19806
    • Gallagher, F.A.1    Kettunen, M.I.2    Hu, D.-E.3    Jensen, P.R.4    Zandt, R.I.5    Karlsson, M.6
  • 27
    • 78049307949 scopus 로고    scopus 로고
    • Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate
    • Witney TH, Kettunen MI, Hu D, Gallagher FA, Bohndiek SE, Napolitano R, et al. Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate. Br J Cancer 2010;103:1400-6.
    • (2010) Br J Cancer , vol.103 , pp. 1400-1406
    • Witney, T.H.1    Kettunen, M.I.2    Hu, D.3    Gallagher, F.A.4    Bohndiek, S.E.5    Napolitano, R.6
  • 28
    • 78650472851 scopus 로고    scopus 로고
    • Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy
    • Bohndiek SE, Kettunen MI, Hu D, Witney TH, Kennedy BWC, Gallagher FA, et al. Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy. Mol Cancer Ther 2010;9:3278-88.
    • (2010) Mol Cancer Ther , vol.9 , pp. 3278-3288
    • Bohndiek, S.E.1    Kettunen, M.I.2    Hu, D.3    Witney, T.H.4    Kennedy, B.W.C.5    Gallagher, F.A.6
  • 29
    • 0034042444 scopus 로고    scopus 로고
    • Pyruvate: Metabolic protector of cardiac performance
    • Mallet RT. Pyruvate: metabolic protector of cardiac performance. Proc Soc Exp Biol Med 2000;223:136-48.
    • (2000) Proc Soc Exp Biol Med , vol.223 , pp. 136-148
    • Mallet, R.T.1
  • 30
    • 75849149496 scopus 로고    scopus 로고
    • Hyperpolarized 13C magnetic resonance metabolic imaging: Application to brain tumors
    • Park I, Larson PEZ, Zierhut ML, Hu S, Bok R, Ozawa T, et al. Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors. Neuro Oncol 2010;12:133-44.
    • (2010) Neuro Oncol , vol.12 , pp. 133-144
    • Park, I.1    Larson, P.E.Z.2    Zierhut, M.L.3    Hu, S.4    Bok, R.5    Ozawa, T.6
  • 31
    • 33845292936 scopus 로고    scopus 로고
    • Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis
    • Golman K, Zandt RI, Lerche M, Pehrson R, Ardenkjaer-Larsen JH. Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis. Cancer Res 2006;66:10855-60.
    • (2006) Cancer Res , vol.66 , pp. 10855-10860
    • Golman, K.1    Zandt, R.I.2    Lerche, M.3    Pehrson, R.4    Ardenkjaer-Larsen, J.H.5
  • 32
    • 35948970970 scopus 로고    scopus 로고
    • Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy
    • Day SE, Kettunen MI, Gallagher FA, Hu D-E, Lerche M, Wolber J, et al. Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy. Nat Med 2007;13: 1382-7.
    • (2007) Nat Med , vol.13 , pp. 1382-1387
    • Day, S.E.1    Kettunen, M.I.2    Gallagher, F.A.3    Hu, D.-E.4    Lerche, M.5    Wolber, J.6
  • 33
    • 77957343186 scopus 로고    scopus 로고
    • Hyperpolarized 13C spectroscopic imaging informs on hypoxia-inducible factor-1 and myc activity downstream of platelet-derived growth factor receptor
    • Dafni H, Larson PEZ, Hu S, Yoshihara HAI, Ward CS, Venkatesh HS, et al. Hyperpolarized 13C spectroscopic imaging informs on hypoxia-inducible factor-1 and myc activity downstream of platelet-derived growth factor receptor. Cancer Res 2010;70:7400-10.
    • (2010) Cancer Res , vol.70 , pp. 7400-7410
    • Dafni, H.1    Larson, P.E.Z.2    Hu, S.3    Yoshihara, H.A.I.4    Ward, C.S.5    Venkatesh, H.S.6
  • 34
    • 76749161366 scopus 로고    scopus 로고
    • Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy
    • Ward CS, Venkatesh HS, Chaumeil MM, Brandes AH, Vancriekinge M, Dafni H, et al. Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy. Cancer Res 2010;70:1296-1305.
    • (2010) Cancer Res , vol.70 , pp. 1296-1305
    • Ward, C.S.1    Venkatesh, H.S.2    Chaumeil, M.M.3    Brandes, A.H.4    Vancriekinge, M.5    Dafni, H.6
  • 35
    • 79251566788 scopus 로고    scopus 로고
    • Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1-13C]pyruvate and 13C magnetic resonance spectroscopic imaging
    • Day SE, Kettunen MI, Cherukuri MK, Mitchell JB, Lizak MJ, Morris HD, et al. Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1-13C]pyruvate and 13C magnetic resonance spectroscopic imaging. Magn Reson Med 2011;65:557-63.
    • (2011) Magn Reson Med , vol.65 , pp. 557-563
    • Day, S.E.1    Kettunen, M.I.2    Cherukuri, M.K.3    Mitchell, J.B.4    Lizak, M.J.5    Morris, H.D.6
  • 36
    • 84880855809 scopus 로고    scopus 로고
    • Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors
    • Dutta P, Le A, Vander Jagt DL, Tsukamoto T, Martinez GV, Dang CV, et al. Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors. Cancer Res 2013;73:4190-5.
    • (2013) Cancer Res , vol.73 , pp. 4190-4195
    • Dutta, P.1    Le, A.2    Vander Jagt, D.L.3    Tsukamoto, T.4    Martinez, G.V.5    Dang, C.V.6
  • 38
    • 38549166422 scopus 로고    scopus 로고
    • New approaches for imaging tumour responses to treatment
    • Brindle K. New approaches for imaging tumour responses to treatment. Nat. Rev. Cancer 2008;8:94-107.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 94-107
    • Brindle, K.1
  • 39
    • 80051763253 scopus 로고    scopus 로고
    • Targeted-therapy and imaging response: A new paradigm for clinical evaluation?
    • Milano A, Perri F, Ciarmiello A, Caponigro F. Targeted-therapy and imaging response: a new paradigm for clinical evaluation? Rev Recent Clin Trials 2011;6:259-65.
    • (2011) Rev Recent Clin Trials , vol.6 , pp. 259-265
    • Milano, A.1    Perri, F.2    Ciarmiello, A.3    Caponigro, F.4
  • 41
    • 4644259265 scopus 로고    scopus 로고
    • Kinase inhibition with BAY 43-9006 in renal cell carcinoma
    • Ahmad T, Eisen T. Kinase inhibition with BAY 43-9006 in renal cell carcinoma. Clin Cancer Res 2004;10:6388S-92S.
    • (2004) Clin Cancer Res , vol.10
    • Ahmad, T.1    Eisen, T.2
  • 42
    • 16844376769 scopus 로고    scopus 로고
    • Phase I/II trial of BAY 43-9006, carboplatin, and paclitaxel demonstrates preliminary antitumor activity in the expansion cohort of patients with metastatic melanoma
    • abstr 7507
    • Flaherty KT, Brose M, Schuchter LM, Tuveson D, Lee R, Schwartz B, et al. Phase I/II trial of BAY 43-9006, carboplatin, and paclitaxel demonstrates preliminary antitumor activity in the expansion cohort of patients with metastatic melanoma. J Clin Oncol 2004;22:14S (abstr 7507).
    • (2004) J Clin Oncol , vol.22
    • Flaherty, K.T.1    Brose, M.2    Schuchter, L.M.3    Tuveson, D.4    Lee, R.5    Schwartz, B.6
  • 43
    • 4644276593 scopus 로고    scopus 로고
    • Preliminary antitumor activity of BAY 43-9006 in metastatic renal cell carcinoma and other advanced refractory solid tumors in a phase II randomized discontinuation trial (RDT)
    • abstr 4501
    • Ratain MJ, Flaherty KT, Stadler WM, O'Dwyer P, Kaye S, Xiong H, et al. Preliminary antitumor activity of BAY 43-9006 in metastatic renal cell carcinoma and other advanced refractory solid tumors in a phase II randomized discontinuation trial (RDT). J Clin Oncol 2004;22:14S (abstr 4501).
    • (2004) J Clin Oncol , vol.22
    • Ratain, M.J.1    Flaherty, K.T.2    Stadler, W.M.3    O'Dwyer, P.4    Kaye, S.5    Xiong, H.6
  • 44
    • 0033738008 scopus 로고    scopus 로고
    • Quantitative assessment of tumor metabolism using FDG-PET imaging
    • Weber WA, Schwaiger M, Avril N. Quantitative assessment of tumor metabolism using FDG-PET imaging. Nucl Med Biol 2000;27:683-7.
    • (2000) Nucl Med Biol , vol.27 , pp. 683-687
    • Weber, W.A.1    Schwaiger, M.2    Avril, N.3
  • 45
    • 0036794518 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced MRI in clinical oncology: Current status and future directions
    • Padhani AR. Dynamic contrast-enhanced MRI in clinical oncology: current status and future directions. J Magn Reson Imaging 2002;16: 407-22.
    • (2002) J Magn Reson Imaging , vol.16 , pp. 407-422
    • Padhani, A.R.1
  • 46
    • 0034544590 scopus 로고    scopus 로고
    • Apoptosis and proliferation as predictors of chemotherapy response in patients with breast carcinoma
    • Chang J, Ormerod M, Powles TJ, Allred DC, Ashley SE, Dowsett M. Apoptosis and proliferation as predictors of chemotherapy response in patients with breast carcinoma. Cancer 2000;89:2145-52.
    • (2000) Cancer , vol.89 , pp. 2145-2152
    • Chang, J.1    Ormerod, M.2    Powles, T.J.3    Allred, D.C.4    Ashley, S.E.5    Dowsett, M.6
  • 47
    • 84857227950 scopus 로고    scopus 로고
    • Hyperpolarized 13C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization
    • Bohndiek SE, Kettunen MI, Hu DE, Brindle KM. Hyperpolarized 13C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization. Cancer Res 2012;72:854-64.
    • (2012) Cancer Res , vol.72 , pp. 854-864
    • Bohndiek, S.E.1    Kettunen, M.I.2    Hu, D.E.3    Brindle, K.M.4
  • 48
    • 0036198715 scopus 로고    scopus 로고
    • Reproducibility of dynamic contrast-enhanced MRI in human muscle and tumours: Comparison of quantitative and semiquantitative analysis
    • Galbraith SM, Lodge MA, Taylor NJ, Rustin GJS, Bentzen S, Stirling JJ, et al. Reproducibility of dynamic contrast-enhanced MRI in human muscle and tumours: comparison of quantitative and semiquantitative analysis. NMR Biomed 2002;15:132-42.
    • (2002) NMR Biomed , vol.15 , pp. 132-142
    • Galbraith, S.M.1    Lodge, M.A.2    Taylor, N.J.3    Rustin, G.J.S.4    Bentzen, S.5    Stirling, J.J.6
  • 49
    • 70849085768 scopus 로고    scopus 로고
    • Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells
    • Harris T, Eliyahu G, Frydman L, Degani H. Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells. Proc Natl Acad Sci U S A 2009;106:18131-6.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 18131-18136
    • Harris, T.1    Eliyahu, G.2    Frydman, L.3    Degani, H.4
  • 50
    • 34547218143 scopus 로고    scopus 로고
    • The role of monocarboxylate transporter 2 and 4 in the transport of gamma-hydroxybutyric acid in mammalian cells
    • Wang Q, Morris ME. The role of monocarboxylate transporter 2 and 4 in the transport of gamma-hydroxybutyric acid in mammalian cells. Drug Metab Dispos 2007;35:1393-9.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1393-1399
    • Wang, Q.1    Morris, M.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.