Proton concentrations can be a major contributor to the modification of osteoclast and osteoblast differentiation, working independently of extracellular bicarbonate ions

Journal of Bone and Mineral Metabolism

Volumn 32, Issue 1, 2014, Pages 17-28

  Kato, Kohtaro ^a   Matsushita, Misao ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b TOKAI UNIVERSITY   (Japan)

Author keywords

Bicarbonate ion; Osteoblast; Osteoclast; Proton; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ALKALINE PHOSPHATASE; BICARBONATE; MESSENGER RNA; PROTON; REACTIVE OXYGEN METABOLITE; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 4;

ACIDOSIS; ANIMAL CELL; ARTICLE; BONE METABOLISM; BONE MINERAL; BONE MINERALIZATION; CELL DIFFERENTIATION; CONTROLLED STUDY; DETERIORATION; ENZYME ACTIVITY; HOMEOSTASIS; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; PH; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANIMALS; BICARBONATES; BONE AND BONES; BUCLADESINE; BUFFERS; CALCIFICATION, PHYSIOLOGIC; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; CULTURE MEDIA; EXTRACELLULAR SPACE; HYDROGEN-ION CONCENTRATION; IONS; MICE; OSTEOBLASTS; OSTEOCLASTS; PROTONS; RNA, MESSENGER; TIME FACTORS; TRPV CATION CHANNELS;

EID: 84893814471     PISSN: 09148779     EISSN: 14355604     Source Type: Journal    
DOI: 10.1007/s00774-013-0462-9     Document Type: Article

References (33)

1. Kingsley LA, Fournier PG, Chirgwin JM, Guise TA (2007) Molecular biology of bone metastasis. Mol Cancer Ther 6:2609-2617
2. Kraut JA, Kurtz I (2005) Metabolic acidosis of CKD: diagnosis, clinical characteristics and treatment. Am J Kidney Dis 45:978-993
3. Lewis JS, Lee JA, Underwood JC, Harris AL, Lewis CE (1999) Macrophage responses to hypoxia: relevance to disease mechanisms. J Leukoc Biol 66:889-900
4. Everaerts W, Vriens J, Owsianik G, Appendino G, Voets T, De Ridder D, Nilius B (2010) Functional characterization of transient receptor potential channels in mouse urothelial cells. Am J Physiol Renal Physiol 298:F692-F701
5. Idris AI, Landao-Bassonga E, Ralston SH (2010) The TRPV1 ion channel antagonist capsazepine inhibits osteoclast and osteoblast differentiation in vitro and ovariectomy induced bone loss in vivo. Bone (NY) 46:1089-1099
6. Pedersen SF, Owsianik G, Nilius B (2005) TRP channels: an overview. Cell Calcium 38:233-252
7. Frick KK, Krieger NS, Nehrke K, Bushinsky DA (2009) Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. J Bone Miner Res 24:305-313
8. Tomura H, Mogi C, Sato K, Okajima F (2005) Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: a novel type of multi-functional receptors. Cell Signal 17:1466-1476
9. Deval E, Gasull X, Noël J, Salinas M, Baron A, Diochot S, Lingueglia E (2010) Acid-sensing ion channels (ASICs): pharmacology and implication in pain. Pharmacol Ther 128:549-558
10. Dawson-Hughes B, Harris SS, Palermo NJ, Castaneda-Sceppa C, Rasmussen HM, Dallal GE (2009) Treatment with potassium bicarbonate lowers calcium excretion and bone resorption in older men and women. J Clin Endocrinol Metab 94:96-102
11. Graf H, Arieff AI (1986) The use of sodium bicarbonate in the therapy of organic acidosis. Intensive Care Med 12:285-288
12. Buclin T, Cosma M, Appenzeller M, Jacquet AF, Décosterd LA, Biollaz J, Burckhardt P (2001) Diet acids and alkalis influence calcium retention in bone. Osteoporos Int 12:493-499
13. Ching SV, Norrdin RW, Fettman MJ, LeCouteur RA (1990) Trabecular bone remodeling and bone mineral density in the adult cat during chronic dietary acidification with ammonium chloride. J Bone Miner Res 5:547-556
14. Geng W, Hill K, Zerwekh JE, Kohler T, Müller R, Moe OW (2009) Inhibition of osteoclast formation and function by bicarbonate: role of soluble adenylyl cyclase. J Cell Physiol 220:332-340
15. Frick KK, Bushinsky DA (1998) Chronic metabolic acidosis reversibly inhibits extracellular matrix gene expression in mouse osteoblasts. Am J Physiol 275:F840-F847
16. Meghji S, Morrison MS, Handerson B, Arnet TR (2001) pH dependence of bone resorption: mouse calvarial osteoclasts are activated by acidosis. Am J Physiol Endocrinol Metab 280:E112-E119
17. Krieger NS, Bushinsky DA (2011) Pharmacological inhibition of intracellular calcium release blocks acid-induced bone resorption. Am J Physiol Renal Physiol 300:F91-F97
18. Kato K, Morita I (2011) Acidosis environment promotes osteoclast formation by acting on the last phase of preosteoclast differentiation: a study to elucidate the action points of acidosis and search for putative target molecules. Eur J Pharmacol 663:27-39
19. Gregory CA, Gunn WG, Peister A, Prockop DJ (2004) An alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction. Anal Biochem 329:77-84
20. Lee NK, Choi YG, Baik JY, Han SY, Jeong DW, Bae YS, Kim N, Lee SY (2005) A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation. Blood 106:852-859
21. 2+ oscillations essential for osteoclastogenesis. J Biol Chem 285:6913-6921
22. Cioffi DL (2011) Redox regulation of endothelial canonical transient receptor potential channels. Antioxid Redox Signal 15:1567-1582
23. Marone CC, Wong NL, Sutton RA, Dirks JH (1981) Acidosis and renal calcium excretion in experimental chronic renal failure. Nephron 28:294-296
24. Petito SL, Evans JL (1984) Calcium status of the growing rat as affected by diet acidity from ammonium chloride, phosphate and protein. J Nutr 114:1049-1059
25. Downey GP, Elson EL, Schwab B, Erzurum SC, Young SK, Worthen GS (1991) Biophysical properties and microfilament assembly in neutrophils: modulation by cyclic AMP. J Cell Biol 114:1179-1190
26. Granholm S, Lundberg P, Lerner UH (2007) Calcitonin inhibits osteoclast formation in mouse haematopoetic cells independently of transcriptional regulation by receptor activator of NF-kappa-B and c-Fms. J Endocrinol 195:415-427
27. Kajiya H, Okamoto F, Fukushima H, Okabe K (2003) Calcitonin inhibits proton extrusion in resorbing rat osteoclasts via protein kinase A. Pflugers Arch 445:651-658
28. Disthabanchong S, Radinahamed P, Stitchantrakul W, Hongeng S, Rajatanavin R (2007) Chronic metabolic acidosis alters osteoblast differentiation from human mesenchymal stem cells. Kidney Int 71:201-209
29. Arnett TR (2010) Acidosis, hypoxia and bone. Arch Biochem Biophys 503:103-109
30. Frick KK, Bushinsky DA (1998) Chronic metabolic acidosis reversibly inhibits extracellular matrix gene expression in mouse osteoblasts. Am J Physiol Renal Physiol 275:F840-F847
31. Almeida M, Han L, Ambrogini E, Weinstein RS, Manolagas SC (2011) Glucocorticoids and tumor necrosis factor α increase oxidative stress and suppress Wnt protein signaling in osteoblasts. J Biol Chem 286:44326-44335
32. Riemann A, Schneider B, Ihling A, Nowak M, Sauvant C, Thews O, Gekle M (2011) Acidic environment leads to ROS-induced MAPK signaling in cancer cells. PLoS ONE 6:e22445
33. Hool LC, Corry B (2007) Redox control of calcium channels: from mechanisms to therapeutic opportunities. Antioxid Redox Signal 9:409-435