Immune-mediated myopathy related to anti 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies as an emerging cause of necrotizing myopathy induced by statins

Joint Bone Spine

Volumn 81, Issue 1, 2014, Pages 79-82

  Lahaye, Clément ^a   Beaufrére, Anne Marie ^a   Boyer, Olivier ^b,c   Drouot, Laurent ^b   Soubrier, Martin ^a   Tournadre, Anne ^a  

^a UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^b NORMANDIE UNIVERSITÉ   (France)

^c ROUEN UNIVERSITY HOSPITAL   (France)

Author keywords

Anti HMGCR; Myositis; Necrotizing myopathy; Statin

Indexed keywords

COMPLEMENT MEMBRANE ATTACK COMPLEX; CREATININE; GLIMEPIRIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE ANTIBODY; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN G; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; METHOTREXATE; MUSCLE PROTEIN; PREDNISONE; PROTEIN ANTIBODY; RAMIPRIL; ROSUVASTATIN; STEROID; UNCLASSIFIED DRUG; 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A; ACYL COENZYME A; AUTOANTIBODY; IMMUNOGLOBULIN; COMPLEMENT; CREATINE KINASE; FLUORINE 18; HLA ANTIGEN CLASS 1;

AGED; ANTIBODY SCREENING; ARTICLE; CASE REPORT; CD8+ T LYMPHOCYTE; CLINICAL FEATURE; COMPLEMENT DEPOSITION; CREATININE BLOOD LEVEL; DIFFERENTIAL DIAGNOSIS; ENDURANCE; ENZYME ACTIVE SITE; FASCICULATION; FLUORESCENCE; FLUORESCENCE ANALYSIS; HISTOPATHOLOGY; HUMAN; IMMUNE MEDIATED NECROTIZING MYOPATHY; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATORY INFILTRATE; LYMPHOCYTIC INFILTRATION; MALE; MUSCLE ATROPHY; MUSCLE BIOPSY; MUSCLE CELL; MUSCLE STRENGTH; MUSCLE WEAKNESS; MYALGIA; MYOPATHY; MYOSITIS; POLYMYOSITIS; PROTEIN EXPRESSION; QUADRICEPS FEMORIS MUSCLE; STEROID THERAPY; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; AUTOIMMUNE DISEASES; BIOPSY; ENZYMOLOGY; IMMUNOLOGY; MUSCULAR DISEASES; NECROSIS; PATHOLOGY; SKELETAL MUSCLE; ANTIBODY DETECTION; ANTIBODY TITER; ANTIHYPERTENSIVE THERAPY; ARM; AUTOIMMUNE DISEASE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CREATINE KINASE BLOOD LEVEL; DIABETES MELLITUS; DRUG EXPOSURE; DRUG INDUCED DISEASE; DRUG WITHDRAWAL; GASTROINTESTINAL ENDOSCOPY; HYPERTENSION; LEG; MUSCLE LEVEL; MUSCLE NECROSIS; NEUROLOGIC EXAMINATION; PELVIC EXAMINATION; PROTEIN ANALYSIS; SKIN EXAMINATION; THORAX EXAMINATION;

ACYL COENZYME A; AGED; AUTOANTIBODIES; AUTOIMMUNE DISEASES; BIOPSY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMUNOGLOBULINS, INTRAVENOUS; MALE; MUSCLE, SKELETAL; MUSCULAR DISEASES; NECROSIS;

EID: 84893781701     PISSN: 1297319X     EISSN: 17787254     Source Type: Journal    
DOI: 10.1016/j.jbspin.2013.06.008     Document Type: Article

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