Case 5-2014: A 59-year-old man with fever, confusion, thrombocytopenia, rash, and renal failure

New England Journal of Medicine

Volumn 370, Issue 7, 2014, Pages 651-660

  Baggett, Meridale V ^a,b   Turbett, Sarah E ^a,b   Schwartzenberg, Shmuel S ^a,b   Stone, James R ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; GLUCOSE; IBUPROFEN; LACTIC ACID; NALOXONE;

ADULT; AORTITIS; ARTICLE; BACTERIAL ENDOCARDITIS; BLOOD PRESSURE MEASUREMENT; BODY TEMPERATURE MEASUREMENT; BREATHING RATE; CASE REPORT; CONFUSION; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; DYSPHAGIA; ELECTROCARDIOGRAM; FATIGUE; FEVER; GLASGOW COMA SCALE; HUMAN; INFECTIOUS AORTITIS; KIDNEY FAILURE; MALE; MIDDLE AGED; MUSCLE RIGIDITY; MYALGIA; OCCULT BLOOD; OXYGEN SATURATION; PRIORITY JOURNAL; PULSE RATE; RASH; SEPTIC VASCULOPATHY; SINUS TACHYCARDIA; THROMBOCYTE COUNT; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA; TICK BORNE DISEASE; VASCULAR DISEASE; VOMITING; AORTA; AORTA VALVE; CLINICAL OBSERVATION; CLINICAL STUDY; DIAGNOSIS; KIDNEY; MICROBIOLOGY; PATHOLOGY; ROCKY MOUNTAIN SPOTTED FEVER; SKIN; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; TRANSESOPHAGEAL ECHOCARDIOGRAPHY;

AORTA; AORTIC VALVE; AORTITIS; CONFUSION; DIAGNOSIS, DIFFERENTIAL; ECHOCARDIOGRAPHY, TRANSESOPHAGEAL; ENDOCARDITIS, BACTERIAL; EXANTHEMA; FEVER; HUMANS; KIDNEY; MALE; MIDDLE AGED; RENAL INSUFFICIENCY; ROCKY MOUNTAIN SPOTTED FEVER; SKIN; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; THROMBOCYTOPENIA;

EID: 84893779702     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcpc1310004     Document Type: Article

References (20)

1. Bell WR, Braine HG, Ness PM, Kickler TS. Improved survival in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: clinical experience in 108 patients. N Engl J Med 1991;325:398-403.
2. Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever, ehrlichioses, and anaplasmosis - United States: a practical guide for physicians and other health-care and public health professionals. MMWR Recomm Rep 2006;55(RR-4):1-27.
3. Rao AK, Schapira M, Clements ML, et al. A prospective study of platelets and plasma proteolytic systems during the early stages of Rocky Mountain spotted fever. N Engl J Med 1988;318:1021-8. (Pubitemid 18095006)
4. Helmick CG, Bernard KW, D'Angelo LJ. Rocky Mountain spotted fever: clinical, laboratory, and epidemiological features of 262 cases. J Infect Dis 1984;150:480-8. (Pubitemid 14013966)
5. Centers for Disease Control and Prevention. Rocky Mountain spotted fever: statistics and epidemiology (http://www.cdc.gov/rmsf/stats).
6. Asherson RA, Cervera R, Piette JC, et al. Catastrophic antiphospholipid syndrome: clues to the pathogenesis from a series of 80 patients. Medicine (Baltimore) 2001;80:355-77. (Pubitemid 33070843)
7. Delgado-Jiménez Y, Fraga J, Requena C, et al. Acute bacterial septic vasculopathy. Int J Dermatol 2013;52:1071-80.
8. Roberson JC II, Ludmer LM, Feinman MC, Barth WF. Subacute bacterial endocarditis with polyarthritis mimicking thrombotic thrombocytopenic purpura: a case report. J Clin Rheumatol 1995;1:118-21.
9. Chirinos JA, Corrales-Medina VF, Garcia S, Lichtstein DM, Bisno AL, Chakko S. Endocarditis associated with antineutrophil cytoplasmic antibodies: a case report and review of the literature. Clin Rheumatol 2007;26:590-5. (Pubitemid 46359307)
10. Murray HW, Tuazon CU, Sheagren JN. Staphylococcal septicemia and disseminated intravascular coagulation: Staphylococcus aureus endocarditis mimicking meningococcemia. Arch Intern Med 1977;137:844-7. (Pubitemid 9041085)
11. McKinsey DS, Ratts TE, Bisno AL. Underlying cardiac lesions in adults with infective endocarditis: the changing spectrum. Am J Med 1987;82:681-8.
12. Murdoch DR, Corey GR, Hoen B, et al. Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study. Arch Intern Med 2009;169:463-73.
13. Farrior JB, Silverman ME. A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis. Chest 1976;70:239-43.
14. Gunson TH, Oliver GF. Osler's nodes and Janeway lesions. Australas J Dermatol 2007;48:251-5. (Pubitemid 47621747)
15. Li JS, Sexton DJ, Mick N, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis 2000;30:633-8.
16. Stone JR, Basso C, Baandrup UT, et al. Recommendations for processing cardiovascular surgical pathology specimens: a consensus statement from the Standards and Definitions Committee of the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology. Cardiovasc Pathol 2012;21:2-16.
17. Castonguay MC, Burner KD, Edwards WD, Baddour LM, Maleszewski JJ. Surgical pathology of native valve endocarditis in 310 specimens from 287 patients (1985-2004). Cardiovasc Pathol 2013;22:19-27.
18. Thiene G, Basso C. Pathology and pathogenesis of infective endocarditis in native heart valves. Cardiovasc Pathol 2006;15:256-63. (Pubitemid 44345241)
19. Siddiquee Z, Zane NA, Smith RN, Stone JR. Dense IgG4 plasma cell infiltrates associated with chronic infectious aortitis: implications for the diagnosis of IgG4-related disease. Cardiovasc Pathol 2012;21:470-5.
20. Miller DV, Oderich GS, Aubry MC, Panneton JM, Edwards WD. Surgical pathology of infected aneurysms of the descending thoracic and abdominal aorta: clinicopathologic correlations in 29 cases (1976 to 1999). Hum Pathol 2004;35:1112-20. (Pubitemid 39165344)