Wound dehiscence after abdominoperineal resection for low rectal cancer is associated with decreased survival

Diseases of the Colon and Rectum

Volumn 57, Issue 2, 2014, Pages 143-150

  Hawkins, Alexander T ^a   Berger, David L ^a   Shellito, Paul C ^a   Sylla, Patrica ^a   Bordeianou, Liliana ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Abdominoperineal resection; Complication; Dehiscence; Rectal adenocarcinoma; Survival

Indexed keywords

ADULT; AGED; ARTICLE; BODY MASS; CANCER RECURRENCE; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; INCIDENCE; INFLAMMATORY BOWEL DISEASE; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MEDICAL HISTORY; MEDICAL RECORD REVIEW; MIDDLE AGED; OBSERVATIONAL STUDY; PERINEAL WOUND DEHISCENCE; PERINEUM INJURY; PNEUMONIA; POSTOPERATIVE COMPLICATION; RECTUM ABDOMINOPERINEAL RESECTION; RECTUM CARCINOMA; RETROSPECTIVE STUDY; SURGICAL INFECTION; SURGICAL MORTALITY; SURVIVAL RATE; SURVIVAL TIME; TERTIARY CARE CENTER; UNIVERSITY HOSPITAL; URINARY TRACT INFECTION; URINE RETENTION; VERY ELDERLY; WOUND DEHISCENCE; WOUND INFECTION; YOUNG ADULT;

ABDOMEN; ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BODY MASS INDEX; FEMALE; HUMANS; MALE; MIDDLE AGED; PERINEUM; RECTAL NEOPLASMS; RETROSPECTIVE STUDIES; RISK FACTORS; SURGICAL FLAPS; SURGICAL WOUND DEHISCENCE; YOUNG ADULT;

EID: 84893774972     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1097/DCR.0000000000000027     Document Type: Article

References (38)

1. García-Aguilar J, Hernandez de Anda E, Sirivongs P, Lee SH, Madoff RD, Rothenberger DA. A pathologic complete response to preoperative chemoradiation is associated with lower local recurrence and improved survival in rectal cancer patients treated by mesorectal excision. Dis Colon Rectum. 2003;46:298-304.
2. Chen ET, Mohiuddin M, Brodovsky H, Fishbein G, Marks G. Downstaging of advanced rectal cancer following combined preoperative chemotherapy and high dose radiation. Int J Radiat Oncol Biol Phys. 1994;30:169-175.
3. M insky BD, Cohen AM, Enker WE, Paty P. Sphincter preservation with preoperative radiation therapy and coloanal anastomosis. Int J Radiat Oncol Biol Phys. 1995;31:553-559.
4. T heodoropoulos G, Wise WE, Padmanabhan A, et al. T-level downstaging and complete pathologic response after preoperative chemoradiation for advanced rectal cancer result in decreased recurrence and improved disease-free survival. Dis Colon Rectum. 2002;45:895-903.
5. M oore HG, Gittleman AE, Minsky BD, et al. Rate of pathologic complete response with increased interval between preoperative combined modality therapy and rectal cancer resection. Dis Colon Rectum. 2004;47:279-286.
6. T ilney HS, Heriot AG, Purkayastha S, et al. A national perspective on the decline of abdominoperineal resection for rectal cancer. Ann Surg. 2008;247:77-84.
7. N agtegaal ID, van de Velde CJ, Marijnen CA, van Krieken JH, Quirke P; Dutch Colorectal Cancer Group; Pathology Review Committee. Low rectal cancer: A call for a change of approach in abdominoperineal resection. J Clin Oncol. 2005;23:9257-9264.
8. West NP, Finan PJ, Anderin C, Lindholm J, Holm T, Quirke P. Evidence of the oncologic superiority of cylindrical abdominoperineal excision for low rectal cancer. J Clin Oncol. 2008;26:3517-3522.
9. Weiser MR, Quah HM, Shia J, et al. Sphincter preservation in low rectal cancer is facilitated by preoperative chemoradiation and intersphincteric dissection. Ann Surg. 2009;249:236-242.
10. S ilberfein EJ, Kattepogu KM, Hu CY, et al. Long-term survival and recurrence outcomes following surgery for distal rectal cancer. Ann Surg Oncol. 2010;17:2863-2869.
11. T ekkis PP, Heriot AG, Smith J, Thompson MR, Finan P, Stamatakis JD; Association of Coloproctology of Great Britain and Ireland. Comparison of circumferential margin involvement between restorative and nonrestorative resections for rectal cancer. Colorectal Dis. 2005;7:369-374.
12. A nderin C, Martling A, Hellborg H, Holm T. A populationbased study on outcome in relation to the type of resection in low rectal cancer. Dis Colon Rectum. 2010;53:753-760.
13. S telzner S, Koehler C, Stelzer J, Sims A, Witzigmann H. Extended abdominoperineal excision vs. standard abdominoperineal excision in rectal cancer-a systematic overview. Int J Colorectal Dis. 2011;26:1227-1240.
14. S telzner S, Hellmich G, Schubert C, Puffer E, Haroske G, Witzigmann H. Short-term outcome of extra-levator abdominoperineal excision for rectal cancer. Int J Colorectal Dis. 2011;26:919-925.
15. H olm T, Ljung A, Häggmark T, Jurell G, Lagergren J. Extended abdominoperineal resection with gluteus maximus flap reconstruction of the pelvic floor for rectal cancer. Br J Surg. 2007;94:232-238.
16. L efevre JH, Parc Y, Kernéis S, et al. Abdomino-perineal resection for anal cancer: Impact of a vertical rectus abdominis myocutaneus flap on survival, recurrence, morbidity, and wound healing. Ann Surg. 2009;250:707-711.
17. S unesen KG, Buntzen S, Tei T, Lindegaard JC, Nørgaard M, Laurberg S. Perineal healing and survival after anal cancer salvage surgery: 10-year experience with primary perineal reconstruction using the vertical rectus abdominis myocutaneous (VRAM) flap. Ann Surg Oncol. 2009;16:68-77.
18. NIH Consensus Conference. Adjuvant therapy for patients with colon and rectal cancer. JAMA. 1990;264:1444-1450.
19. A rtioukh DY, Smith RA, Gokul K. Risk factors for impaired healing of the perineal wound after abdominoperineal resection of rectum for carcinoma. Colorectal Dis. 2007;9:362-367.
20. Chessin DB, Hartley J, Cohen AM, et al. Rectus flap reconstruction decreases perineal wound complications after pelvic chemoradiation and surgery: A cohort study. Ann Surg Oncol. 2005;12:104-110.
21. Butler CE, Gündeslioglu AO, Rodriguez-Bigas MA. Outcomes of immediate vertical rectus abdominis myocutaneous flap reconstruction for irradiated abdominoperineal resection defects. J Am Coll Surg. 2008;206:694-703.
22. Nelson RA, Butler CE. Surgical outcomes of VRAM versus thigh flaps for immediate reconstruction of pelvic and perineal cancer resection defects. Plast Reconstr Surg. 2009;123:175-183.
23. F arid H, O'Connell TX. Methods to decrease the morbidity of abdominoperineal resection. Am Surg. 1995;61:1061-1064.
24. L una-Pérez P, Rodríguez-Ramírez S, Vega J, Sandoval E, Labastida S. Morbidity and mortality following abdominoperineal resection for low rectal adenocarcinoma. Rev Invest Clin. 2001;53:388-395.
25. Christian CK, Kwaan MR, Betensky RA, Breen EM, Zinner MJ, Bleday R. Risk factors for perineal wound complications following abdominoperineal resection. Dis Colon Rectum. 2005;48:43-48.
26. H arris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)-a metadatadriven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42:377-381.
27. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis. 1987;40:373-383.
28. Bullard KM, Trudel JL, Baxter NN, Rothenberger DA. Primary perineal wound closure after preoperative radiotherapy and abdominoperineal resection has a high incidence of wound failure. Dis Colon Rectum. 2005;48:438-443.
29. N issan A, Guillem JG, Paty PB, et al. Abdominoperineal resection for rectal cancer at a specialty center. Dis Colon Rectum. 2001;44:27-35.
30. Wiatrek RL, Thomas JS, Papaconstantinou HT. Perineal wound complications after abdominoperineal resection. Clin Colon Rectal Surg. 2008;21:76-85.
31. Miles W. A method of of perfoming abdominoperineal resection for adenocarcinoma of the low rectum. Lancet. 1908;2:1812.
32. H ay JM, Fingerhut A, Paquet JC, Flamant Y. Management of the pelvic space with or without omentoplasty after abdominoperineal resection for carcinoma of the rectum: A prospective multicenter study-The French Association for Surgical Research. Eur J Surg. 1997;163:199-206.
33. Page CP, Carlton PK Jr, Becker DW. Closure of the pelvic and perineal wounds after removal of the rectum and anus. Dis Colon Rectum. 1980;23:2-9.
34. M oreaux J, Horiot A, Barrat F, Mabille J. Obliteration of the pelvic space with pedicled omentum after excision of the rectum for cancer. Am J Surg. 1984;148:640-644.
35. O'Leary DP. Use of the greater omentum in colorectal surgery. Dis Colon Rectum. 1999;42:533-539.
36. van der Wal BC, Cleffken BI, Gulec B, Kaufman HS, Choti MA. Results of salvage abdominoperineal resection for recurrent anal carcinoma following combined chemoradiation therapy. J Gastrointest Surg. 2001;5:383-387.
37. Biagi JJ, Raphael MJ, Mackillop WJ, Kong W, King WD, Booth CM. Association between time to initiation of adjuvant chemotherapy and survival in colorectal cancer: A systematic review and meta-analysis. JAMA. 2011;305:2335-2342.
38. Foster JD, Pathak S, Smart NJ, et al. Reconstruction of the perineum following extralevator abdominoperineal excision for carcinoma of the lower rectum: A systematic review. Colorectal Dis. 2012;14:1052-1059.