Effect of Korean herbal medicine combined with a probiotic mixture on diarrhea-dominant irritable bowel syndrome: A double-blind, randomized, placebo-controlled trial

Evidence-based Complementary and Alternative Medicine

Volumn 2013, Issue , 2013, Pages

  Ko, Seok Jae ^a   Han, Gajin ^a   Kim, Seul Ki ^a   Seo, Jae Gu ^b   Chung, Won Seok ^b   Ryu, Bongha ^a   Kim, Jinsung ^a   Yeo, Inkwon ^c   Lee, Beom Joon ^a   Lee, Jin Moo ^a   Park, Jae Woo ^a  

^a Kyung Hee University   (South Korea)

^b Cellbiotech Co Ltd   (South Korea)

^c Sookmyung Women's University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84893753857     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/824605     Document Type: Article

References (46)

1. Longstreth G. F., Thompson W. G., Chey W. D., Houghton L. A., Mearin F., Spiller R. C., Functional bowel disorders. Gastroenterology 2006 130 5 1480 1491 2-s2.0-33646201684 10.1053/j.gastro.2005.11.061
2. Chang F. Y., The current prevalence of irritable bowel syndrome in Asia. Journal of Neurogastroenterology and Motility 2010 16 4 389 400 10.5056/jnm.2010.16.4.389
3. Duracinsky M., Chassany O., How can an effective drug to treat irritable bowel syndrome be successfully developed? Gastroenterologie Clinique et Biologique 2009 33 1 S26 S34 2-s2.0-62249100617 10.1016/S0399-8320(09)71522-2
4. Rajilić-Stojanović M., Biagi E., Heilig H. G. H. J., Kajander K., Kekkonen R. A., Tims S., de Vos W. M., Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. Gastroenterology 2011 141 5 1792 1801 2-s2.0-80054857288 10.1053/j.gastro.2011.07.043
5. Dunlop S. P., Hebden J., Campbell E., Naesdal J., Olbe L., Perkins A. C., Spiller R. C., Abnormal intestinal permeability in subgroups of diarrhea-predominant irritable bowel syndromes. American Journal of Gastroenterology 2006 101 6 1288 1294 2-s2.0-33744830627 10.1111/j.1572-0241. 2006.00672.x (Pubitemid 43829995)
6. Wu J. C. Y., Complementary and alternative medicine modalities for the treatment of irritable bowel syndrome: facts or myths? Gastroenterology and Hepatology 2010 6 11 705 711 2-s2.0-78650437832
7. Kim Y. B., Kim J. H., Chae B. Y., Effects on Koakhyangieonggisan and Gamikoahyangieonggisan on the digestive and anti-allergic function. Journal of Korean Medical Society 1993 10 11 23
8. Ryu K. W., Ryu B. H., Yun H. S., Park D. W., Experimental comparative studies on the effects of Kwakhyangjeonggisan and Souminkwakhyang-jeonggisan. Journal of Korean Medical College of KyungHee University 1998 21
9. Han J. H., Kim G. B., Han I. S., Shim Y. S., Kim E. G., A clinical report of chronic diarrhea treated with GwakHyang-JungGiSan. Journal of Korean Internal Medicine 2005 26 889 896
10. Liu J. P., Yang M., Liu Y. X., Wei M. L., Grimsgaard S., Herbal medicines for treatment of irritable bowel syndrome. Cochrane Database of Systematic Reviews 2006 1 CD004116 2-s2.0-33645518857 10.1002/14651858.CD004116.pub2
11. Cha B. K., Jung S. M., Choi C. H., Song I.-D., Lee H. W., Kim H. J., Hyuk J., Chang S. K., Kim K., Chung W.-S., Seo J.-G., The effect of a multispecies probiotic mixture on the symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. Journal of Clinical Gastroenterology 2012 46 3 220 227 2-s2.0-84857039944 10.1097/MCG.0b013e31823712b1
12. Herbal formula and lactic acid bacteria. http://www.akomnews.com/subpage/ search-detail.php?code =A001&uid=53825&page=/subpage/search. php&nowpage=1&search-word
13. Ko S.-J., Ryu B., Kim J., Hong B.-G., Yeo I., Lee B.-J., Lee J.-M., Park J.-W., Effect of herbal extract granules combined with probiotic mixture on irritable bowel syndrome with diarrhea: study protocol for a randomized controlled trial. Trials 2011 12, article 219 2-s2.0-80053532829 10.1186/1745-6215-12-219
14. Kim H. J., Camilleri M., McKinzie S., Lempke M. B., Burton D. D., Thomforde G. M., Zinsmeister A. R., A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea-predominant irritable bowel syndrome. Alimentary Pharmacology and Therapeutics 2003 17 7 895 904 2-s2.0-0037392231 10.1046/j.1365-2036.2003.01543.x (Pubitemid 36459602)
15. Vejdani R., Shalmani H. R. M., Mir-Fattahi M., Sajed-Nia F., Abdollahi M., Zali M. R., Alizadeh A. H. M., Bahari A., Amin G., The efficacy of an herbal medicine, Carmint, on the relief of abdominal pain and bloating in patients with irritable bowel syndrome: a pilot study. Digestive Diseases and Sciences 2006 51 8 1501 1507 2-s2.0-33748190277 10.1007/s10620-006-9079-3 (Pubitemid 44315821)
16. Kim H. J., Vazquez Roque M. I., Camilleri M., Stephens D., Burton D. D., Baxter K., Thomforde G., Zinsmeister A. R., A randomized controlled trial of a probiotic combination VSL# 3 and placebo in irritable bowel syndrome with bloating. Neurogastroenterology and Motility 2005 17 5 687 696 2-s2.0-25844477007 10.1111/j.1365-2982.2005.00695.x (Pubitemid 41400717)
17. Lewis S. J., Heaton K. W., Stool form scale as a useful guide to intestinal transit time. Scandinavian Journal of Gastroenterology 1997 32 9 920 924 2-s2.0-0030868530 (Pubitemid 27382038)
18. Coulie B., Szarka L. A., Camilleri M., Burton D. D., McKinzie S., Stambler N., Cedarbaum J. M., Recombinant human neurotrophic factors accelerate colonic transit and relieve constipation in humans. Gastroenterology 2000 119 1 41 50 2-s2.0-0034234832 (Pubitemid 30452577)
19. Drossman D. A., Patrick D. L., Whitehead W. E., Toner B. B., Diamant N. E., Hu Y., Jia H., Bangdiwala S. I., Further validation of the IBS-QOL: a disease-specific quality-of-life questionnaire. American Journal of Gastroenterology 2000 95 4 999 1007 2-s2.0-0034072849 10.1016/S0002-9270(00) 00733-4 (Pubitemid 30196737)
20. Park J. M., Choi M.-G., Oh J. H., Cho Y. K., Lee I. S., Kim S. W., Choi K. Y., Chung I.-S., Cross-cultural validation of irritable bowel syndrome quality of life in Korea. Digestive Diseases and Sciences 2006 51 8 1478 1484 2-s2.0-33748162276 10.1007/s10620-006-9084-6 (Pubitemid 44315818)
21. Zhou Q., Zhang B., Nicholas Verne G., Intestinal membrane permeability and hypersensitivity in the irritable bowel syndrome. Pain 2009 146 1-2 41 46 2-s2.0-70349799526 10.1016/j.pain.2009.06.017
22. Hollander D., Intestinal permeability, leaky gut, and intestinal disorders. Current Gastroenterology Reports 1999 1 5 410 416 2-s2.0-0033205262
23. Camilleri M., Gorman H., Intestinal permeability and irritable bowel syndrome. Neurogastroenterology and Motility 2007 19 7 545 552 2-s2.0-34250877518 10.1111/j.1365-2982.2007.00925.x (Pubitemid 46985594)
24. Malinen E., Krogius-Kurikka L., Lyra A., Nikkilä J., Jääskeläinen A., Rinttilä T., Vilpponen-Salmela T., von Wright A. J., Palva A., Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome. World Journal of Gastroenterology 2010 16 36 4532 4540 2-s2.0-77957591287 10.3748/wjg.v16.i36.4532
25. Wang C., Nishino N., Presence of sourdough lactic acid bacteria in commercial total mixed ration silage as revealed by denaturing gradient gel electrophoresis analysis. Letters in Applied Microbiology 2010 51 4 436 442 2-s2.0-77956635800 10.1111/j.1472-765X.2010.02915.x
26. Hoveyda N., Heneghan C., Mahtani K. R., Perera R., Roberts N., Glasziou P., A systematic review and meta-analysis: probiotics in the treatment of irritable bowel syndrome. BMC Gastroenterology 2009 9, article 15 2-s2.0-63049127784 10.1186/1471-230X-9-15
27. Rahimi R., Abdollahi M., Herbal medicines for the management of irritable bowel syndrome: a comprehensive review. World Journal of Gastroenterology 2012 18 7 589 600 2-s2.0-84857410412 10.3748/wjg.v18.i7.589
28. Leung W. K., Wu J. C. Y., Liang S. M., Chan L. S., Chan F. K. L., Xie H., Fung S. S. L., Hui A. J., Wong V. W. S., Che C.-T., Sung J. J. Y., Treatment of diarrhea-predominant irritable bowel syndrome with traditional Chinese herbal medicine: a randomized placebo-controlled trial. American Journal of Gastroenterology 2006 101 7 1574 1580 2-s2.0-33745583485 10.1111/j.1572-0241. 2006.00576.x (Pubitemid 43980632)
29. O'Mahony L., Mccarthy J., Kelly P., Hurley G., Luo F., Chen K., O'Sullivan G. C., Kiely B., Collins J. K., Shanahan F., Quigley E. M. M., Lactobacillus and Bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology 2005 128 3 541 551 2-s2.0-15744374565 10.1053/j.gastro.2004.11.050 (Pubitemid 40585355)
30. Camilleri M., Is there a role for probiotics in irritable bowel syndrome? Digestive and Liver Disease 2006 38 2 S266 S269 2-s2.0-33846452536 10.1016/S1590-8658(07)60007-3 (Pubitemid 46140766)
31. Pathmakanthan S., Li C. K. F., Cowie J., Hawkey C. J., Lactobacillus plantarum 299: beneficial in vitro immunomodulation in cells extracted from inflamed human colon. Journal of Gastroenterology and Hepatology 2004 19 2 166 173 2-s2.0-1342332301 10.1111/j.1440-1746.2004.03181.x (Pubitemid 38253356)
32. Ménard S., Candalh C., Bambou J. C., Terpend K., Cerf-Bensussan N., Heyman M., Lactic acid bacteria secrete metabolites retaining anti-inflammatory properties after intestinal transport. Gut 2004 53 6 821 828 2-s2.0-2442655096 10.1136/gut.2003.026252 (Pubitemid 38662131)
33. Chapman C. M. C., Gibson G. R., Rowland I., Health benefits of probiotics: are mixtures more effective than single strains? European Journal of Nutrition 2011 50 1 1 17 2-s2.0-78651076407 10.1007/s00394-010-0166-z
34. Enck P., Zimmermann K., Menke G., Müller-Lissner S., Martens U., Klosterhalfen S., A mixture of Escherichia coli (DSM 17252) and Enterococcus faecalis (DSM 16440) for treatment of the irritable bowel syndrome-a randomized controlled trial with primary care physicians. Neurogastroenterology and Motility 2008 20 10 1103 1109 2-s2.0-51449104087 10.1111/j.1365-2982.2008.01156. x
35. Whorwell P. J., Altringer L., Morel J., Bond Y., Charbonneau D., O'Mahony L., Kiely B., Shanahan F., Quigley E. M. M., Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. American Journal of Gastroenterology 2006 101 7 1581 1590 2-s2.0-33745569311 10.1111/j.1572-0241.2006.00734.x (Pubitemid 43980633)
36. Niv E., Naftali T., Hallak R., Vaisman N., The efficacy of Lactobacillus reuteri ATCC 55730 in the treatment of patients with irritable bowel syndrome-a double blind, placebo-controlled, randomized study. Clinical Nutrition 2005 24 6 925 931 2-s2.0-28944452948 10.1016/j.clnu.2005.06.001 (Pubitemid 41782449)
37. O'Sullivan M. A., O'Morain C. A., Bacterial supplementation in the irritable bowel syndrome. A randomised double-blind placebo-controlled crossover study. Digestive and Liver Disease 2000 32 4 294 301 2-s2.0-0033921870 (Pubitemid 30445067)
38. Madisch A., Holtmann G., Plein K., Hotz J., Treatment of irritable bowel syndrome with herbal preparations: results of a double-blind, randomized, placebo-controlled, multi-centre trial. Alimentary Pharmacology and Therapeutics 2004 19 3 271 279 2-s2.0-1342310220 10.1111/j.1365-2036.2004.01859.x (Pubitemid 38253501)
39. Wang G., Li T.-Q., Wang L., Xia Q., Chang J., Zhang Y., Wan M.-H., Guo J., Cheng Y., Huang X., Zhang R.-M., Tong-xie-ning, a Chinese herbal formula, in treatment of diarrhea-predominant irritable bowel syndrome: a prospective, randomized, double-blind, placebo-controlled trial. Zhanghua Yixue Zazhi 2006 119 24 2114 2119 2-s2.0-33845911966 (Pubitemid 46017674)
40. Pan F., Zhang T., Zhang Y.-H., Xu J.-J., Chen F.-M., Effect of Tongxie Yaofang granule in treating diarrhea-predominate irritable bowel syndrome. Chinese Journal of Integrative Medicine 2009 15 3 216 219 2-s2.0-67650472840 10.1007/s11655-009-0216-7
41. Si J.-M., Yu Y.-C., Fan Y.-J., Chen S.-J., Intestinal microecology and quality of life in irritable bowel syndrome patients. World Journal of Gastroenterology 2004 10 12 1802 1805 2-s2.0-3142767014 (Pubitemid 38931209)
42. Kassinen A., Krogius-Kurikka L., Mäkivuokko H., Rinttilä T., Paulin L., Corander J., Malinen E., Apajalahti J., Palva A., The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects. Gastroenterology 2007 133 1 24 33 2-s2.0-34447104397 10.1053/j.gastro.2007.04.005 (Pubitemid 47031125)
43. Fan Y.-J., Chen S.-J., Yu Y.-C., Si J.-M., Liu B., A probiotic treatment containing Lactobacillus, Bifidobacterium and Enterococcus improves IBS symptoms in an open label trial. Journal of Zhejiang University Science B 2006 7 12 987 991 2-s2.0-36349013902 10.1631/jzus.2006.B0987
44. Rajilić-Stojanović M., Biagi E., Heilig H. G. H. J., Kajander K., Kekkonen R. A., Tims S., de Vos W. M., Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. Gastroenterology 2011 141 5 1792 1801 2-s2.0-80054857288 10.1053/j.gastro.2011.07.043
45. di Leo V., D'Incà R., Diaz-Granado N., Fries W., Venturi C., D'Odorico A., Martines D., Sturniolo G. C., Lactulose/mannitol test has high efficacy for excluding organic causes of chronic diarrhea. American Journal of Gastroenterology 2003 98 10 2245 2252 2-s2.0-0142152616 10.1016/S0002-9270(03) 00703-2 (Pubitemid 37305366)
46. Xie Y.-C., Tang F., Experimental study on protecting intestinal barrier function of Huoxiang Zhengqi soft capsule. Zhongguo Zhong Yao Za Zhi 2004 29 5 456 458 2-s2.0-23844528967