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Volumn 34, Issue 3, 2014, Pages 353-361

Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure

Author keywords

Acute liver failure; Azoxymethane; Blood brain barrier; Endotoxemia; Immunoglobulin G extravasation; Lipopolysaccharide; Matrix metalloproteinase 9; Pro inflammatory cytokines; Systemic inflammatory response

Indexed keywords

25 KDA PROTEIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; AZOXYMETHANE; ENDOTOXIN; GELATINASE B; IMMUNOGLOBULIN G; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AMINOTRANSFERASE; AMMONIA; CYTOKINE; MMP9 PROTEIN, MOUSE;

EID: 84893716063     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12252     Document Type: Article
Times cited : (53)

References (42)
  • 1
    • 0033807687 scopus 로고    scopus 로고
    • The systemic inflammatory response syndrome in acute liver failure
    • Rolando N, Wade J, Davalos M, et al. The systemic inflammatory response syndrome in acute liver failure. Hepatology 2000; 32: 734-9.
    • (2000) Hepatology , vol.32 , pp. 734-739
    • Rolando, N.1    Wade, J.2    Davalos, M.3
  • 2
    • 0042471690 scopus 로고    scopus 로고
    • Infection and the progression of hepatic encephalopathy in acute liver failure
    • Vaquero J, Polson J, Chung C, et al. Infection and the progression of hepatic encephalopathy in acute liver failure. Gastroenterology 2003; 125: 755-64.
    • (2003) Gastroenterology , vol.125 , pp. 755-764
    • Vaquero, J.1    Polson, J.2    Chung, C.3
  • 3
    • 0031895023 scopus 로고    scopus 로고
    • Removal of endotoxin and cytokines by plasma exchange in patients with acute hepatic failure
    • Iwai H, Nagaki M, Naito T, et al. Removal of endotoxin and cytokines by plasma exchange in patients with acute hepatic failure. Crit Care Med 1998; 26: 873-6.
    • (1998) Crit Care Med , vol.26 , pp. 873-876
    • Iwai, H.1    Nagaki, M.2    Naito, T.3
  • 4
    • 0000352873 scopus 로고
    • Galactosamine-induced sensitization to the lethal effects of endotoxin
    • Galanos C, Freudenberg MA, Reutter W. Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc Natl Acad Sci USA 1979; 76: 5939-43.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 5939-5943
    • Galanos, C.1    Freudenberg, M.A.2    Reutter, W.3
  • 5
    • 0034948382 scopus 로고    scopus 로고
    • Increased intracranial pressure in a porcine model of fulminant hepatic failure using amatoxin and endotoxin
    • Takada Y, Ishiguro S, Fukunaga K, et al. Increased intracranial pressure in a porcine model of fulminant hepatic failure using amatoxin and endotoxin. J Hepatol 2001; 34: 825-31.
    • (2001) J Hepatol , vol.34 , pp. 825-831
    • Takada, Y.1    Ishiguro, S.2    Fukunaga, K.3
  • 6
    • 33645857685 scopus 로고    scopus 로고
    • Neurobiological characterization of an azoxymethane mouse model of acute liver failure
    • Belanger M, Cote J, Butterworth RF. Neurobiological characterization of an azoxymethane mouse model of acute liver failure. Neurochem Int 2006; 48: 434-40.
    • (2006) Neurochem Int , vol.48 , pp. 434-440
    • Belanger, M.1    Cote, J.2    Butterworth, R.F.3
  • 7
    • 46649105540 scopus 로고    scopus 로고
    • Altered expression of zonula occludens-2 precedes increased blood-brain barrier permeability in a murine model of fulminant hepatic failure
    • Shimojima N, Eckman CB, McKinney M, et al. Altered expression of zonula occludens-2 precedes increased blood-brain barrier permeability in a murine model of fulminant hepatic failure. J Invest Surg 2008; 21: 101-8.
    • (2008) J Invest Surg , vol.21 , pp. 101-108
    • Shimojima, N.1    Eckman, C.B.2    McKinney, M.3
  • 8
    • 0023699970 scopus 로고
    • Haemophilus influenzae lipopolysaccharide-induced blood brain barrier permeability during experimental meningitis in the rat
    • Wispelwey B, Lesse AJ, Hansen EJ, Scheld WM. Haemophilus influenzae lipopolysaccharide-induced blood brain barrier permeability during experimental meningitis in the rat. J Clin Invest 1988; 82: 1339-46.
    • (1988) J Clin Invest , vol.82 , pp. 1339-1346
    • Wispelwey, B.1    Lesse, A.J.2    Hansen, E.J.3    Scheld, W.M.4
  • 10
    • 0030034301 scopus 로고    scopus 로고
    • The influence of cytokines on the integrity of the blood-brain barrier in vitro
    • de Vries HE, Blom-Roosemalen MC, van Oosten M, et al. The influence of cytokines on the integrity of the blood-brain barrier in vitro. J Neuroimmunol 1996; 64: 37-43.
    • (1996) J Neuroimmunol , vol.64 , pp. 37-43
    • de Vries, H.E.1    Blom-Roosemalen, M.C.2    van Oosten, M.3
  • 11
    • 33746924079 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 contributes to brain extravasation and edema in fulminant hepatic failure mice
    • Nguyen JH, Yamamoto S, Steers J, et al. Matrix metalloproteinase-9 contributes to brain extravasation and edema in fulminant hepatic failure mice. J Hepatol 2006; 44: 1105-14.
    • (2006) J Hepatol , vol.44 , pp. 1105-1114
    • Nguyen, J.H.1    Yamamoto, S.2    Steers, J.3
  • 12
    • 69449107598 scopus 로고    scopus 로고
    • Editorial: mouse models to study sepsis syndrome in humans
    • Warren HS. Editorial: mouse models to study sepsis syndrome in humans. J Leukoc Biol 2009; 86: 199-201.
    • (2009) J Leukoc Biol , vol.86 , pp. 199-201
    • Warren, H.S.1
  • 13
    • 77958100217 scopus 로고    scopus 로고
    • Up-regulation of caveolin-1 and blood-brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency
    • Beauchesne E, Desjardins P, Butterworth RF, Hazell AS. Up-regulation of caveolin-1 and blood-brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency. Neurochem Int 2010; 57: 830-7.
    • (2010) Neurochem Int , vol.57 , pp. 830-837
    • Beauchesne, E.1    Desjardins, P.2    Butterworth, R.F.3    Hazell, A.S.4
  • 14
    • 77149125563 scopus 로고    scopus 로고
    • IL-1 or TNF receptor gene deletion delays onset of encephalopathy and attenuates brain edema in experimental acute liver failure
    • Bemeur C, Qu H, Desjardins P, Butterworth RF. IL-1 or TNF receptor gene deletion delays onset of encephalopathy and attenuates brain edema in experimental acute liver failure. Neurochem Int 2010; 56: 213-5.
    • (2010) Neurochem Int , vol.56 , pp. 213-215
    • Bemeur, C.1    Qu, H.2    Desjardins, P.3    Butterworth, R.F.4
  • 15
    • 77954084245 scopus 로고    scopus 로고
    • N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms
    • Bemeur C, Vaquero J, Desjardins P, Butterworth RF. N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms. Metab Brain Dis 2010; 25: 241-9.
    • (2010) Metab Brain Dis , vol.25 , pp. 241-249
    • Bemeur, C.1    Vaquero, J.2    Desjardins, P.3    Butterworth, R.F.4
  • 16
    • 84864778906 scopus 로고    scopus 로고
    • Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathy
    • Rangroo TV, Thrane AS, Chanag J, et al. Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathy. Neuroscience 2012; 220: 247-55.
    • (2012) Neuroscience , vol.220 , pp. 247-255
    • Rangroo, T.V.1    Thrane, A.S.2    Chanag, J.3
  • 17
    • 0032850665 scopus 로고    scopus 로고
    • Azoxymethane-induced fulminant hepatic failure in C57BL/6J mice: characterization of a new animal model
    • Matkowskyj KA, Marrero JA, Carroll RE, et al. Azoxymethane-induced fulminant hepatic failure in C57BL/6J mice: characterization of a new animal model. Am J Physiol 1999; 277: G455-62.
    • (1999) Am J Physiol , vol.277
    • Matkowskyj, K.A.1    Marrero, J.A.2    Carroll, R.E.3
  • 18
    • 0032125487 scopus 로고    scopus 로고
    • Tumor necrosis factor genomic polymorphism and outcome of acetaminophen (paracetamol)-induced acute liver failure
    • Bernal W, Donaldson P, Underhill J, Wendon J, Williams R. Tumor necrosis factor genomic polymorphism and outcome of acetaminophen (paracetamol)-induced acute liver failure. J Hepatol 1998; 29: 53-9.
    • (1998) J Hepatol , vol.29 , pp. 53-59
    • Bernal, W.1    Donaldson, P.2    Underhill, J.3    Wendon, J.4    Williams, R.5
  • 19
    • 0033855570 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha in the pathogenesis of human and murine fulminant hepatic failure
    • Streetz K, Leifeld L, Grundmann D, et al. Tumor necrosis factor alpha in the pathogenesis of human and murine fulminant hepatic failure. Gastroenterology 2000; 119: 446-60.
    • (2000) Gastroenterology , vol.119 , pp. 446-460
    • Streetz, K.1    Leifeld, L.2    Grundmann, D.3
  • 20
    • 84878015639 scopus 로고    scopus 로고
    • Liver-brain proinflammatory signalling in acute liver failure: Role in the pathogenesis of hepatic encephalopathy and brain edema
    • Bemeur C, Butterworth R F. Liver-brain proinflammatory signalling in acute liver failure: Role in the pathogenesis of hepatic encephalopathy and brain edema. Metab Brain Dis 2013; 28: 145-50.
    • (2013) Metab Brain Dis , vol.28 , pp. 145-150
    • Bemeur, C.1    Butterworth, R.F.2
  • 21
    • 0036784144 scopus 로고    scopus 로고
    • Liver derived pro-inflammatory cytokines may be important in producing intracranial hypertension in acute liver failure
    • Jalan R, Pollok A, Shah SH, Madhavan K, Simpson KJ. Liver derived pro-inflammatory cytokines may be important in producing intracranial hypertension in acute liver failure. J Hepatol 2002; 37: 536-8.
    • (2002) J Hepatol , vol.37 , pp. 536-538
    • Jalan, R.1    Pollok, A.2    Shah, S.H.3    Madhavan, K.4    Simpson, K.J.5
  • 22
    • 6944225278 scopus 로고    scopus 로고
    • Influence of TNF gene polymorphism in patients with acute and fulminant hepatitis
    • Tsuchiya N, Tokushige K, Yamaguchi N, et al. Influence of TNF gene polymorphism in patients with acute and fulminant hepatitis. J Gastroenterol 2004; 39: 859-66.
    • (2004) J Gastroenterol , vol.39 , pp. 859-866
    • Tsuchiya, N.1    Tokushige, K.2    Yamaguchi, N.3
  • 23
    • 84869216699 scopus 로고    scopus 로고
    • Inflammatory cascades driven by tumor necrosis factor-alpha play a major role in the progression of acute liver failure and its neurological complications
    • Chastre A, Belanger M, Beauchesne E, et al. Inflammatory cascades driven by tumor necrosis factor-alpha play a major role in the progression of acute liver failure and its neurological complications. PLoS ONE 2012; 7: e49670.
    • (2012) PLoS ONE , vol.7
    • Chastre, A.1    Belanger, M.2    Beauchesne, E.3
  • 24
    • 0032828311 scopus 로고    scopus 로고
    • Pathophysiology of cerebral edema in fulminant hepatic failure
    • Blei AT, Larsen FS. Pathophysiology of cerebral edema in fulminant hepatic failure. J Hepatol 1999; 31: 771-6.
    • (1999) J Hepatol , vol.31 , pp. 771-776
    • Blei, A.T.1    Larsen, F.S.2
  • 25
    • 0026628303 scopus 로고
    • Electron microscopic study of brain capillaries in cerebral edema from fulminant hepatic failure
    • Kato M, Hughes RD, Keays RT, Williams R. Electron microscopic study of brain capillaries in cerebral edema from fulminant hepatic failure. Hepatology 1992; 15: 1060-6.
    • (1992) Hepatology , vol.15 , pp. 1060-1066
    • Kato, M.1    Hughes, R.D.2    Keays, R.T.3    Williams, R.4
  • 26
    • 0031014486 scopus 로고    scopus 로고
    • Regional cerebral edema and chloride space in galactosamine-induced liver failure in rats
    • Gove CD, Hughes RD, Ede RJ, Williams R. Regional cerebral edema and chloride space in galactosamine-induced liver failure in rats. Hepatology 1997; 25: 295-301.
    • (1997) Hepatology , vol.25 , pp. 295-301
    • Gove, C.D.1    Hughes, R.D.2    Ede, R.J.3    Williams, R.4
  • 27
    • 0023607036 scopus 로고
    • Electron microscopic evaluation of brain edema in rabbits with galactosamine-induced fulminant hepatic failure: ultrastructure and integrity of the blood-brain barrier
    • Traber PG, Dal Canto M, Ganger DR, Blei AT. Electron microscopic evaluation of brain edema in rabbits with galactosamine-induced fulminant hepatic failure: ultrastructure and integrity of the blood-brain barrier. Hepatology 1987; 7: 1272-7.
    • (1987) Hepatology , vol.7 , pp. 1272-1277
    • Traber, P.G.1    Dal Canto, M.2    Ganger, D.R.3    Blei, A.T.4
  • 28
    • 77149172049 scopus 로고    scopus 로고
    • No changes in expression of tight junction proteins or blood-brain barrier permeability in azoxymethane-induced experimental acute liver failure
    • Bemeur C, Chastre A, Desjardins P, Butterworth RF. No changes in expression of tight junction proteins or blood-brain barrier permeability in azoxymethane-induced experimental acute liver failure. Neurochem Int 2010; 56: 3.
    • (2010) Neurochem Int , vol.56 , pp. 3
    • Bemeur, C.1    Chastre, A.2    Desjardins, P.3    Butterworth, R.F.4
  • 29
    • 0033055873 scopus 로고    scopus 로고
    • Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration
    • Clemmesen JO, Larsen FS, Kondrup J, Hansen BA, Ott P. Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration. Hepatology 1999; 29: 648-53.
    • (1999) Hepatology , vol.29 , pp. 648-653
    • Clemmesen, J.O.1    Larsen, F.S.2    Kondrup, J.3    Hansen, B.A.4    Ott, P.5
  • 30
    • 29144519910 scopus 로고    scopus 로고
    • Persistent arterial hyperammonemia increases the concentration of glutamine and alanine in the brain and correlates with intracranial pressure in patients with fulminant hepatic failure
    • Tofteng F, Hauerberg J, Hansen BA, et al. Persistent arterial hyperammonemia increases the concentration of glutamine and alanine in the brain and correlates with intracranial pressure in patients with fulminant hepatic failure. J Cereb Blood Flow Metab 2006; 26: 21-7.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 21-27
    • Tofteng, F.1    Hauerberg, J.2    Hansen, B.A.3
  • 31
    • 0030253214 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor-alpha and interleukin-6 on fluid-phase permeability and ammonia diffusion in CNS-derived endothelial cells
    • Duchini A, Govindarajan S, Santucci M, Zampi G, Hofman FM. Effects of tumor necrosis factor-alpha and interleukin-6 on fluid-phase permeability and ammonia diffusion in CNS-derived endothelial cells. J Investig Med 1996; 44: 474-82.
    • (1996) J Investig Med , vol.44 , pp. 474-482
    • Duchini, A.1    Govindarajan, S.2    Santucci, M.3    Zampi, G.4    Hofman, F.M.5
  • 32
    • 0022972426 scopus 로고
    • Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors
    • Lai JC, Cooper AJ. Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors. J Neurochem 1986; 47: 1376-86.
    • (1986) J Neurochem , vol.47 , pp. 1376-1386
    • Lai, J.C.1    Cooper, A.J.2
  • 33
    • 0037311146 scopus 로고    scopus 로고
    • Selective increase of brain lactate synthesis in experimental acute liver failure: results of a [H-C] nuclear magnetic resonance study
    • Zwingmann C, Chatauret N, Leibfritz D, Butterworth RF. Selective increase of brain lactate synthesis in experimental acute liver failure: results of a [H-C] nuclear magnetic resonance study. Hepatology 2003; 37: 420-8.
    • (2003) Hepatology , vol.37 , pp. 420-428
    • Zwingmann, C.1    Chatauret, N.2    Leibfritz, D.3    Butterworth, R.F.4
  • 34
    • 20144367962 scopus 로고    scopus 로고
    • Lactate induces tumour necrosis factor-alpha, interleukin-6 and interleukin-1beta release in microglial- and astroglial-enriched primary cultures
    • Andersson AK, Ronnback L, Hansson E. Lactate induces tumour necrosis factor-alpha, interleukin-6 and interleukin-1beta release in microglial- and astroglial-enriched primary cultures. J Neurochem 2005; 93: 1327-33.
    • (2005) J Neurochem , vol.93 , pp. 1327-1333
    • Andersson, A.K.1    Ronnback, L.2    Hansson, E.3
  • 35
    • 0033992249 scopus 로고    scopus 로고
    • Human immunodeficiency virus type-1 Nef protein induces blood-brain barrier disruption in the rat: role of matrix metalloproteinase-9
    • Sporer B, Koedel U, Paul R, et al. Human immunodeficiency virus type-1 Nef protein induces blood-brain barrier disruption in the rat: role of matrix metalloproteinase-9. J Neuroimmunol 2000; 102: 125-30.
    • (2000) J Neuroimmunol , vol.102 , pp. 125-130
    • Sporer, B.1    Koedel, U.2    Paul, R.3
  • 36
    • 0033581392 scopus 로고    scopus 로고
    • Early appearance of activated matrix metalloproteinase-9 and blood-brain barrier disruption in mice after focal cerebral ischemia and reperfusion
    • Fujimura M, Gasche Y, Morita-Fujimura Y, et al. Early appearance of activated matrix metalloproteinase-9 and blood-brain barrier disruption in mice after focal cerebral ischemia and reperfusion. Brain Res 1999; 842: 92-100.
    • (1999) Brain Res , vol.842 , pp. 92-100
    • Fujimura, M.1    Gasche, Y.2    Morita-Fujimura, Y.3
  • 37
    • 0028825270 scopus 로고
    • Matrix metalloproteinases in brain injury
    • Rosenberg GA. Matrix metalloproteinases in brain injury. J Neurotrauma 1995; 12: 833-42.
    • (1995) J Neurotrauma , vol.12 , pp. 833-842
    • Rosenberg, G.A.1
  • 38
    • 77950615545 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 in fulminant hepatic failure
    • author reply 76.
    • Palenzuela L, Mas A, Montaner J, Cordoba J. Matrix metalloproteinase-9 in fulminant hepatic failure. Hepatology 2010; 51: 1475-6; author reply 76.
    • (2010) Hepatology , vol.51 , pp. 1475-1476
    • Palenzuela, L.1    Mas, A.2    Montaner, J.3    Cordoba, J.4
  • 39
    • 0027122363 scopus 로고
    • Bacterial meningitis: pathogenesis, pathophysiology, and progress
    • Quagliarello V, Scheld WM. Bacterial meningitis: pathogenesis, pathophysiology, and progress. N Engl J Med 1992; 327: 864-72.
    • (1992) N Engl J Med , vol.327 , pp. 864-872
    • Quagliarello, V.1    Scheld, W.M.2
  • 40
    • 0026596353 scopus 로고
    • In vivo relationship of tumor necrosis factor-alpha to blood-brain barrier damage in patients with active multiple sclerosis
    • Sharief MK, Thompson EJ. In vivo relationship of tumor necrosis factor-alpha to blood-brain barrier damage in patients with active multiple sclerosis. J Neuroimmunol 1992; 38: 27-33.
    • (1992) J Neuroimmunol , vol.38 , pp. 27-33
    • Sharief, M.K.1    Thompson, E.J.2
  • 41
    • 35448939296 scopus 로고    scopus 로고
    • Brain cytokine flux in acute liver failure and its relationship with intracranial hypertension
    • Wright G, Shawcross D, Olde Damink SW, Jalan R. Brain cytokine flux in acute liver failure and its relationship with intracranial hypertension. Metab Brain Dis 2007; 22: 375-88.
    • (2007) Metab Brain Dis , vol.22 , pp. 375-388
    • Wright, G.1    Shawcross, D.2    Olde Damink, S.W.3    Jalan, R.4
  • 42
    • 62649140616 scopus 로고    scopus 로고
    • Cerebral inflammation contributes to encephalopathy and brain edema in acute liver failure: protective effect of minocycline
    • Jiang W, Desjardins P, Butterworth RF. Cerebral inflammation contributes to encephalopathy and brain edema in acute liver failure: protective effect of minocycline. J Neurochem 2009; 109: 485-93.
    • (2009) J Neurochem , vol.109 , pp. 485-493
    • Jiang, W.1    Desjardins, P.2    Butterworth, R.F.3


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