Spinal IFN-γ-induced protein-10 (CXCL10) mediates metastatic breast cancer-induced bone pain by activation of microglia in rat models

Breast Cancer Research and Treatment

Volumn 143, Issue 2, 2014, Pages 255-263

  Bu, Huilian ^a   Shu, Bin ^a   Gao, Feng ^a   Liu, Cheng ^a   Guan, Xuehai ^a   Ke, Changbin ^a   Cao, Fei ^a,b   Hinton, Antentor Othrell ^b   Xiang, Hongbing ^a   Yang, Hui ^a   Tian, Xuebi ^a   Tian, Yuke ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Algogenic molecule; Cancer induced bone pain; Chemokine; CXCL10; Metastatic breast cancer; Microglial activation

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MINOCYCLINE; RECOMBINANT CYTOKINE; ANTIINFECTIVE AGENT; CXCL10 PROTEIN, RAT; CXCR3 PROTEIN, RAT; GAMMA INTERFERON;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BONE METASTASIS; BONE PAIN; BREAST CANCER; CANCER CELL CULTURE; CANCER PAIN; CELL ACTIVATION; FEMALE; INOCULATION; MICROGLIA; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SPINAL CORD; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE TUMOR; CARCINOMA 256, WALKER; CEREBROSPINAL FLUID; CYTOLOGY; DISEASE MODEL; EXPERIMENTAL MAMMARY NEOPLASM; GENE EXPRESSION REGULATION; HYPERALGESIA; METABOLISM; MUSCULOSKELETAL PAIN; PAIN THRESHOLD; PATHOLOGY; SECONDARY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTI-BACTERIAL AGENTS; BONE NEOPLASMS; CARCINOMA 256, WALKER; CHEMOKINE CXCL10; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HYPERALGESIA; INTERFERON-GAMMA; MAMMARY NEOPLASMS, EXPERIMENTAL; MICROGLIA; MINOCYCLINE; MUSCULOSKELETAL PAIN; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CXCR3; SPINAL CORD;

EID: 84893693125     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-013-2807-4     Document Type: Article

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