Eplerenone mimics features of the alternative activation in macrophages obtained from patients with heart failure and healthy volunteers

European Journal of Pharmacology

Volumn 726, Issue 1, 2014, Pages 96-108

  Łabuzek, Krzysztof ^a   Liber, Sebastian ^a   Bułdak, Łukasz ^a   Krupej Kȩdzierska, Joanna ^a   Machnik, Grzegorz ^a   Bobrzyk, Magdalena ^a   Okopień, Bogusław ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Aldosterone; Eplerenone; Heart failure; IL 4; Macrophage

Indexed keywords

ALDOSTERONE; ARGINASE; ARGINASE I, HUMAN; CELL SURFACE RECEPTOR; EPLERENONE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 4; LECTIN; MANNOSE BINDING LECTIN; MANNOSE RECEPTOR; MINERALOCORTICOID ANTAGONIST; MINERALOCORTICOID RECEPTOR; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SPIRONOLACTONE; SUPEROXIDE DISMUTASE;

AGED; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; DRUG INTERACTION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEART FAILURE; HUMAN; IMMUNOLOGY; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; METABOLISM; MIDDLE AGED; NORMAL HUMAN; PHENOTYPE;

AGED; ALDOSTERONE; ARGINASE; CELL SURVIVAL; DRUG INTERACTIONS; FEMALE; GENE EXPRESSION REGULATION; HEALTHY VOLUNTEERS; HEART FAILURE; HUMANS; INTERLEUKIN-4; LECTINS, C-TYPE; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MANNOSE-BINDING LECTINS; MIDDLE AGED; MINERALOCORTICOID RECEPTOR ANTAGONISTS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHENOTYPE; REACTIVE OXYGEN SPECIES; RECEPTORS, CELL SURFACE; RECEPTORS, MINERALOCORTICOID; SPIRONOLACTONE; SUPEROXIDE DISMUTASE;

EID: 84893665971     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.01.043     Document Type: Article

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