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Volumn 108, Issue 1, 2014, Pages 122-128

Adiponectin is associated with dynamic hyperinflation and a favourable response to inhaled glucocorticoids in patients with COPD

Author keywords

Adipokines; Adiponectin; Chronic obstructive pulmonary disease (COPD); Glucocorticoid; Leptin; Pulmonary emphysema

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; BIOLOGICAL MARKER; FIXOTIDE DISKUS; FLUTICASONE PROPIONATE; GELATINASE B; GLUCOCORTICOID; INTERLEUKIN 6; LEPTIN; MYELOPEROXIDASE; UNCLASSIFIED DRUG;

EID: 84893655972     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2013.08.016     Document Type: Article
Times cited : (12)

References (59)
  • 1
    • 34548660457 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    • K.F. Rabe, S. Hurd, A. Anzueto, P.J. Barnes, S.A. Buist, and P. Calverley et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary Am J Respir Crit Care Med 176 2007 532 555
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 532-555
    • Rabe, K.F.1    Hurd, S.2    Anzueto, A.3    Barnes, P.J.4    Buist, S.A.5    Calverley, P.6
  • 2
    • 0141928029 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Molecular and cellular mechanisms
    • P.J. Barnes, S.D. Shapiro, and R.A. Pauwels Chronic obstructive pulmonary disease: molecular and cellular mechanisms Eur Respir J 22 2003 672 688
    • (2003) Eur Respir J , vol.22 , pp. 672-688
    • Barnes, P.J.1    Shapiro, S.D.2    Pauwels, R.A.3
  • 3
    • 74849118542 scopus 로고    scopus 로고
    • Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: Is there a connection?
    • E.F. Wouters, N.L. Reynaert, M.A. Dentener, and J.H. Vernooy Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection? Proc Am Thoracic Soc 6 2009 638 647
    • (2009) Proc Am Thoracic Soc , vol.6 , pp. 638-647
    • Wouters, E.F.1    Reynaert, N.L.2    Dentener, M.A.3    Vernooy, J.H.4
  • 5
    • 34548277025 scopus 로고    scopus 로고
    • From COPD to chronic systemic inflammatory syndrome?
    • L.M. Fabbri, and K.F. Rabe From COPD to chronic systemic inflammatory syndrome? Lancet 370 2007 797 799
    • (2007) Lancet , vol.370 , pp. 797-799
    • Fabbri, L.M.1    Rabe, K.F.2
  • 6
    • 66749141807 scopus 로고    scopus 로고
    • Systemic manifestations and comorbidities of COPD
    • P.J. Barnes, and B.R. Celli Systemic manifestations and comorbidities of COPD Eur Respir J 33 2009 1165 1185
    • (2009) Eur Respir J , vol.33 , pp. 1165-1185
    • Barnes, P.J.1    Celli, B.R.2
  • 7
    • 4644230621 scopus 로고    scopus 로고
    • Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease
    • D.D. Sin, P. Lacy, E. York, and S.F. Man Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease Am J Respir Crit Care Med 170 2004 760 765
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 760-765
    • Sin, D.D.1    Lacy, P.2    York, E.3    Man, S.F.4
  • 8
    • 18144408371 scopus 로고    scopus 로고
    • Adipose tissue, adipokines, and inflammation
    • G. Fantuzzi Adipose tissue, adipokines, and inflammation J Allergy Clin Immunol 115 2005 911 919
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 911-919
    • Fantuzzi, G.1
  • 10
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • T. Yamauchi, J. Kamon, Y. Ito, A. Tsuchida, T. Yokomizo, and S. Kita et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Nature 423 2003 762 769
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3    Tsuchida, A.4    Yokomizo, T.5    Kita, S.6
  • 11
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines: Mediators linking adipose tissue, inflammation and immunity
    • H. Tilg, and A.R. Moschen Adipocytokines: mediators linking adipose tissue, inflammation and immunity Nat Rev Immunol 6 2006 772 783
    • (2006) Nat Rev Immunol , vol.6 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 12
    • 59849096643 scopus 로고    scopus 로고
    • Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease
    • M. Miller, J.Y. Cho, A. Pham, J. Ramsdell, and D.H. Broide Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease J Immunol 182 2009 684 691
    • (2009) J Immunol , vol.182 , pp. 684-691
    • Miller, M.1    Cho, J.Y.2    Pham, A.3    Ramsdell, J.4    Broide, D.H.5
  • 13
    • 49149103250 scopus 로고    scopus 로고
    • A new player in cartilage homeostasis: Adiponectin induces nitric oxide synthase type II and pro-inflammatory cytokines in chondrocytes
    • R. Lago, R. Gomez, M. Otero, F. Lago, R. Gallego, and C. Dieguez et al. A new player in cartilage homeostasis: adiponectin induces nitric oxide synthase type II and pro-inflammatory cytokines in chondrocytes Osteoarthr Cartil 16 2008 1101 1109
    • (2008) Osteoarthr Cartil , vol.16 , pp. 1101-1109
    • Lago, R.1    Gomez, R.2    Otero, M.3    Lago, F.4    Gallego, R.5    Dieguez, C.6
  • 15
    • 81055126964 scopus 로고    scopus 로고
    • Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways
    • A. Koskinen, S. Juslin, R. Nieminen, T. Moilanen, K. Vuolteenaho, and E. Moilanen Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways Arthritis Res Ther 13 2011 R184
    • (2011) Arthritis Res Ther , vol.13 , pp. 184
    • Koskinen, A.1    Juslin, S.2    Nieminen, R.3    Moilanen, T.4    Vuolteenaho, K.5    Moilanen, E.6
  • 18
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
    • G.M. Lord, G. Matarese, J.K. Howard, R.J. Baker, S.R. Bloom, and R.I. Lechler Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression Nature 394 1998 897 901
    • (1998) Nature , vol.394 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3    Baker, R.J.4    Bloom, S.R.5    Lechler, R.I.6
  • 19
    • 0033602850 scopus 로고    scopus 로고
    • Human leptin stimulates proliferation and activation of human circulating monocytes
    • J. Santos-Alvarez, R. Goberna, and V. Sanchez-Margalet Human leptin stimulates proliferation and activation of human circulating monocytes Cell Immunol 194 1999 6 11
    • (1999) Cell Immunol , vol.194 , pp. 6-11
    • Santos-Alvarez, J.1    Goberna, R.2    Sanchez-Margalet, V.3
  • 20
    • 79955654715 scopus 로고    scopus 로고
    • Leptin enhances MMP-1, MMP-3 and MMP-13 production in human osteoarthritic cartilage and correlates with MMP-1 and MMP-3 in synovial fluid from OA patients
    • A. Koskinen, K. Vuolteenaho, R. Nieminen, T. Moilanen, and E. Moilanen Leptin enhances MMP-1, MMP-3 and MMP-13 production in human osteoarthritic cartilage and correlates with MMP-1 and MMP-3 in synovial fluid from OA patients Clin Exp Rheumatol 29 2011 57 64
    • (2011) Clin Exp Rheumatol , vol.29 , pp. 57-64
    • Koskinen, A.1    Vuolteenaho, K.2    Nieminen, R.3    Moilanen, T.4    Moilanen, E.5
  • 21
    • 0029118124 scopus 로고
    • Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus
    • M. Maffei, H. Fei, G.H. Lee, C. Dani, P. Leroy, and Y. Zhang et al. Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus Proc Natl Acad Sci U S A 92 1995 6957 6960
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 6957-6960
    • Maffei, M.1    Fei, H.2    Lee, G.H.3    Dani, C.4    Leroy, P.5    Zhang, Y.6
  • 22
    • 84864953111 scopus 로고    scopus 로고
    • Role of adipokines in atherosclerosis: Interferences with cardiovascular complications in rheumatic diseases
    • M. Scotece, J. Conde, R. Gomez, V. Lopez, J. Pino, and A. Gonzalez et al. Role of adipokines in atherosclerosis: interferences with cardiovascular complications in rheumatic diseases Mediators Inflamm 2012 2012 125458
    • (2012) Mediators Inflamm , vol.2012 , pp. 125458
    • Scotece, M.1    Conde, J.2    Gomez, R.3    Lopez, V.4    Pino, J.5    Gonzalez, A.6
  • 24
    • 58349112948 scopus 로고    scopus 로고
    • Enhanced pulmonary leptin expression in patients with severe COPD and asymptomatic smokers
    • J.H. Vernooy, N.E. Drummen, R.J. van Suylen, R.H. Cloots, G.M. Moller, and K.R. Bracke et al. Enhanced pulmonary leptin expression in patients with severe COPD and asymptomatic smokers Thorax 64 2009 26 32
    • (2009) Thorax , vol.64 , pp. 26-32
    • Vernooy, J.H.1    Drummen, N.E.2    Van Suylen, R.J.3    Cloots, R.H.4    Moller, G.M.5    Bracke, K.R.6
  • 25
    • 84866065449 scopus 로고    scopus 로고
    • Leptin, adiponectin and pulmonary diseases
    • N. Ali Assad, and A. Sood Leptin, adiponectin and pulmonary diseases Biochimie 94 2012 2180 2189
    • (2012) Biochimie , vol.94 , pp. 2180-2189
    • Ali Assad, N.1    Sood, A.2
  • 26
    • 58149462249 scopus 로고    scopus 로고
    • The expression of adiponectin receptors and the effects of adiponectin and leptin on airway smooth muscle cells
    • J.H. Shin, J.H. Kim, W.Y. Lee, and J.Y. Shim The expression of adiponectin receptors and the effects of adiponectin and leptin on airway smooth muscle cells Yonsei Med J 49 2008 804 810
    • (2008) Yonsei Med J , vol.49 , pp. 804-810
    • Shin, J.H.1    Kim, J.H.2    Lee, W.Y.3    Shim, J.Y.4
  • 27
    • 84865220197 scopus 로고    scopus 로고
    • Adipokine adipsin is associated with the degree of lung fibrosis in asbestos-exposed workers
    • S. Leivo-Korpela, L. Lehtimaki, R. Nieminen, P. Oksa, T. Vierikko, and R. Jarvenpaa et al. Adipokine adipsin is associated with the degree of lung fibrosis in asbestos-exposed workers Respir Med 106 2012 1435 1440
    • (2012) Respir Med , vol.106 , pp. 1435-1440
    • Leivo-Korpela, S.1    Lehtimaki, L.2    Nieminen, R.3    Oksa, P.4    Vierikko, T.5    Jarvenpaa, R.6
  • 28
    • 84858018869 scopus 로고    scopus 로고
    • Increased alveolar nitric oxide and systemic inflammation markers in silica-exposed workers
    • R. Sauni, P. Oksa, L. Lehtimaki, P. Toivio, P. Palmroos, and R. Nieminen et al. Increased alveolar nitric oxide and systemic inflammation markers in silica-exposed workers Occup Environ Med 69 2012 256 260
    • (2012) Occup Environ Med , vol.69 , pp. 256-260
    • Sauni, R.1    Oksa, P.2    Lehtimaki, L.3    Toivio, P.4    Palmroos, P.5    Nieminen, R.6
  • 29
    • 34248643424 scopus 로고    scopus 로고
    • Quantification of emphysema: A composite physiologic index derived from CT estimation of disease extent
    • S.R. Desai, D.M. Hansell, A. Walker, S.L. MacDonald, F. Chabat, and A.U. Wells Quantification of emphysema: a composite physiologic index derived from CT estimation of disease extent Eur Radiol 17 2007 911 918
    • (2007) Eur Radiol , vol.17 , pp. 911-918
    • Desai, S.R.1    Hansell, D.M.2    Walker, A.3    Macdonald, S.L.4    Chabat, F.5    Wells, A.U.6
  • 30
    • 12344263724 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Thin-section CT measurement of airway wall thickness and lung attenuation
    • I. Orlandi, C. Moroni, G. Camiciottoli, M. Bartolucci, M. Pistolesi, and N. Villari et al. Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuation Radiology 234 2005 604 610
    • (2005) Radiology , vol.234 , pp. 604-610
    • Orlandi, I.1    Moroni, C.2    Camiciottoli, G.3    Bartolucci, M.4    Pistolesi, M.5    Villari, N.6
  • 31
    • 84155163931 scopus 로고    scopus 로고
    • Adipokines: Biofactors from white adipose tissue. A complex hub among inflammation, metabolism, and immunity
    • J. Conde, M. Scotece, R. Gomez, V. Lopez, J.J. Gomez-Reino, and F. Lago et al. Adipokines: biofactors from white adipose tissue. A complex hub among inflammation, metabolism, and immunity Biofactors 37 2011 413 420
    • (2011) Biofactors , vol.37 , pp. 413-420
    • Conde, J.1    Scotece, M.2    Gomez, R.3    Lopez, V.4    Gomez-Reino, J.J.5    Lago, F.6
  • 32
    • 77949717546 scopus 로고    scopus 로고
    • Obesity, adipokines, and lung disease
    • A. Sood Obesity, adipokines, and lung disease J Appl Physiol 108 2010 744 753
    • (2010) J Appl Physiol , vol.108 , pp. 744-753
    • Sood, A.1
  • 34
    • 84865172175 scopus 로고    scopus 로고
    • ECLIPSE investigators (evaluation of COPD longitudinally to identify predictive surrogate endpoints). Dysregulated adipokine metabolism in chronic obstructive pulmonary disease
    • M.K. Breyer, E.P. Rutten, N.W. Locantore, M.L. Watkins, B.E. Miller, and E.F. Wouters ECLIPSE investigators (evaluation of COPD longitudinally to identify predictive surrogate endpoints). Dysregulated adipokine metabolism in chronic obstructive pulmonary disease Eur J Clin Investig 42 2012 983 991
    • (2012) Eur J Clin Investig , vol.42 , pp. 983-991
    • Breyer, M.K.1    Rutten, E.P.2    Locantore, N.W.3    Watkins, M.L.4    Miller, B.E.5    Wouters, E.F.6
  • 35
    • 34447543108 scopus 로고    scopus 로고
    • Elevated circulating plasma adiponectin in underweight patients with COPD
    • K. Tomoda, M. Yoshikawa, T. Itoh, S. Tamaki, A. Fukuoka, and K. Komeda et al. Elevated circulating plasma adiponectin in underweight patients with COPD Chest 132 2007 135 140
    • (2007) Chest , vol.132 , pp. 135-140
    • Tomoda, K.1    Yoshikawa, M.2    Itoh, T.3    Tamaki, S.4    Fukuoka, A.5    Komeda, K.6
  • 36
    • 65649114433 scopus 로고    scopus 로고
    • Adiponectin as a biomarker of systemic inflammatory response in smoker patients with stable and exacerbation phases of chronic obstructive pulmonary disease
    • S. Kirdar, M. Serter, E. Ceylan, A.G. Sener, T. Kavak, and F. Karadag Adiponectin as a biomarker of systemic inflammatory response in smoker patients with stable and exacerbation phases of chronic obstructive pulmonary disease Scand J Clin Lab Investig 69 2009 219 224
    • (2009) Scand J Clin Lab Investig , vol.69 , pp. 219-224
    • Kirdar, S.1    Serter, M.2    Ceylan, E.3    Sener, A.G.4    Kavak, T.5    Karadag, F.6
  • 37
    • 77956594638 scopus 로고    scopus 로고
    • Elevated plasma adiponectin levels in patients with chronic obstructive pulmonary disease
    • K.H. Chan, S.C. Yeung, T.J. Yao, M.S. Ip, A.H. Cheung, and M.M. Chan-Yeung et al. Elevated plasma adiponectin levels in patients with chronic obstructive pulmonary disease Int J Tuberc Lung Dis 14 2010 1193 1200
    • (2010) Int J Tuberc Lung Dis , vol.14 , pp. 1193-1200
    • Chan, K.H.1    Yeung, S.C.2    Yao, T.J.3    Ip, M.S.4    Cheung, A.H.5    Chan-Yeung, M.M.6
  • 40
    • 84855996178 scopus 로고    scopus 로고
    • Vascular smooth muscle cell-derived adiponectin: A paracrine regulator of contractile phenotype
    • M. Ding, A.C. Carrao, R.J. Wagner, Y. Xie, Y. Jin, and E.M. Rzucidlo et al. Vascular smooth muscle cell-derived adiponectin: a paracrine regulator of contractile phenotype J Mol Cell Cardiol 52 2012 474 484
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 474-484
    • Ding, M.1    Carrao, A.C.2    Wagner, R.J.3    Xie, Y.4    Jin, Y.5    Rzucidlo, E.M.6
  • 42
    • 54049105793 scopus 로고    scopus 로고
    • Adiponectin, skeletal muscle adiponectin receptor expression and insulin resistance following dexamethasone
    • C. Jang, W.J. Inder, V.R. Obeyesekere, and F.P. Alford Adiponectin, skeletal muscle adiponectin receptor expression and insulin resistance following dexamethasone Clin Endocrinol (Oxf) 69 2008 745 750
    • (2008) Clin Endocrinol (Oxf) , vol.69 , pp. 745-750
    • Jang, C.1    Inder, W.J.2    Obeyesekere, V.R.3    Alford, F.P.4
  • 43
    • 33748770065 scopus 로고    scopus 로고
    • Short-term dexamethasone administration does not alter serum adiponectin or resistin concentrations in overweight and obese subjects despite an increase in insulin resistance
    • K.C. Lewandowski, K. Szosland, and A. Lewinski Short-term dexamethasone administration does not alter serum adiponectin or resistin concentrations in overweight and obese subjects despite an increase in insulin resistance Clin Endocrinol (Oxf) 65 2006 551 552
    • (2006) Clin Endocrinol (Oxf) , vol.65 , pp. 551-552
    • Lewandowski, K.C.1    Szosland, K.2    Lewinski, A.3
  • 44
    • 33749135475 scopus 로고    scopus 로고
    • Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatment
    • J.V. Patel, D.E. Cummings, J.P. Girod, A.V. Mascarenhas, E.A. Hughes, and M. Gupta et al. Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatment J Negat Results Biomed 5 2006 14
    • (2006) J Negat Results Biomed , vol.5 , pp. 14
    • Patel, J.V.1    Cummings, D.E.2    Girod, J.P.3    Mascarenhas, A.V.4    Hughes, E.A.5    Gupta, M.6
  • 45
    • 67449141057 scopus 로고    scopus 로고
    • The effects of inhaled and oral corticosteroids on serum inflammatory biomarkers in COPD: An exploratory study
    • S.F. Man, Z. Xuekui, R. Vessey, T. Walker, K. Lee, and D. Park et al. The effects of inhaled and oral corticosteroids on serum inflammatory biomarkers in COPD: an exploratory study Therap Adv Respir Dis 3 2009 73 80
    • (2009) Therap Adv Respir Dis , vol.3 , pp. 73-80
    • Man, S.F.1    Xuekui, Z.2    Vessey, R.3    Walker, T.4    Lee, K.5    Park, D.6
  • 47
    • 79955519064 scopus 로고    scopus 로고
    • Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: Implications for therapy
    • K. Nakanishi, Y. Takeda, S. Tetsumoto, T. Iwasaki, K. Tsujino, and H. Kuhara et al. Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: implications for therapy Am J Respir Crit Care Med 183 2011 1164 1175
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1164-1175
    • Nakanishi, K.1    Takeda, Y.2    Tetsumoto, S.3    Iwasaki, T.4    Tsujino, K.5    Kuhara, H.6
  • 48
    • 78649901692 scopus 로고    scopus 로고
    • Adiponectin-deficient mice are protected against tobacco-induced inflammation and increased emphysema
    • M. Miller, A. Pham, J.Y. Cho, P. Rosenthal, and D.H. Broide Adiponectin-deficient mice are protected against tobacco-induced inflammation and increased emphysema Am J Physiol Lung Cell Mol Physiol 299 2010 834 842
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.299 , pp. 834-842
    • Miller, M.1    Pham, A.2    Cho, J.Y.3    Rosenthal, P.4    Broide, D.H.5
  • 49
    • 80155137352 scopus 로고    scopus 로고
    • Evaluation of COPD longitudinally to identify surrogate endpoints (ECLIPSE) study investigators. COPD association and repeatability of blood biomarkers in the ECLIPSE cohort
    • J.A. Dickens, B.E. Miller, L.D. Edwards, E.K. Silverman, D.A. Lomas, and R. Tal-Singer Evaluation of COPD longitudinally to identify surrogate endpoints (ECLIPSE) study investigators. COPD association and repeatability of blood biomarkers in the ECLIPSE cohort Respir Res 12 2011 146
    • (2011) Respir Res , vol.12 , pp. 146
    • Dickens, J.A.1    Miller, B.E.2    Edwards, L.D.3    Silverman, E.K.4    Lomas, D.A.5    Tal-Singer, R.6
  • 50
    • 79957477813 scopus 로고    scopus 로고
    • Gender differences in the adipose secretome system in chronic obstructive pulmonary disease (COPD): A pivotal role of leptin
    • M.K. Breyer, E.P. Rutten, J.H. Vernooy, M.A. Spruit, M.A. Dentener, and C. van der Kallen et al. Gender differences in the adipose secretome system in chronic obstructive pulmonary disease (COPD): a pivotal role of leptin Respir Med 105 2011 1046 1053
    • (2011) Respir Med , vol.105 , pp. 1046-1053
    • Breyer, M.K.1    Rutten, E.P.2    Vernooy, J.H.3    Spruit, M.A.4    Dentener, M.A.5    Van Der Kallen, C.6
  • 52
    • 76749168978 scopus 로고    scopus 로고
    • Leptin, visfatin, insulin resistance, and body composition change in chronic obstructive pulmonary disease
    • S. Eker, L. Ayaz, L. Tamer, and B. Ulubas Leptin, visfatin, insulin resistance, and body composition change in chronic obstructive pulmonary disease Scand J Clin Lab Investig 70 2010 40 44
    • (2010) Scand J Clin Lab Investig , vol.70 , pp. 40-44
    • Eker, S.1    Ayaz, L.2    Tamer, L.3    Ulubas, B.4
  • 53
    • 0036658468 scopus 로고    scopus 로고
    • Direct in vitro effects of androgens and estrogens on ob gene expression and leptin secretion in human adipose tissue
    • F. Machinal-Quelin, M.N. Dieudonne, R. Pecquery, M.C. Leneveu, and Y. Giudicelli Direct in vitro effects of androgens and estrogens on ob gene expression and leptin secretion in human adipose tissue Endocrine 18 2002 179 184
    • (2002) Endocrine , vol.18 , pp. 179-184
    • Machinal-Quelin, F.1    Dieudonne, M.N.2    Pecquery, R.3    Leneveu, M.C.4    Giudicelli, Y.5
  • 54
    • 0033773913 scopus 로고    scopus 로고
    • Disturbances in leptin metabolism are related to energy imbalance during acute exacerbations of chronic obstructive pulmonary disease
    • E.C. Creutzberg, E.F. Wouters, I.M. Vanderhoven-Augustin, M.A. Dentener, and A.M. Schols Disturbances in leptin metabolism are related to energy imbalance during acute exacerbations of chronic obstructive pulmonary disease Am J Respir Crit Care Med 162 2000 1239 1245
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1239-1245
    • Creutzberg, E.C.1    Wouters, E.F.2    Vanderhoven-Augustin, I.M.3    Dentener, M.A.4    Schols, A.M.5
  • 57
    • 79956226689 scopus 로고    scopus 로고
    • Mechanistic modeling of the effects of glucocorticoids and circadian rhythms on adipokine expression
    • S. Sukumaran, W.J. Jusko, D.C. DuBois, and R.R. Almon Mechanistic modeling of the effects of glucocorticoids and circadian rhythms on adipokine expression J Pharmacol Exp Ther 337 2011 734 746
    • (2011) J Pharmacol Exp Ther , vol.337 , pp. 734-746
    • Sukumaran, S.1    Jusko, W.J.2    Dubois, D.C.3    Almon, R.R.4
  • 58
    • 77951244791 scopus 로고    scopus 로고
    • Changes in adiponectin and leptin concentrations during glucocorticoid treatment: A pilot study in patients with polymyalgia rheumatica
    • M.A. Cimmino, G. Andraghetti, L. Briatore, B. Salani, M. Parodi, and M. Cutolo et al. Changes in adiponectin and leptin concentrations during glucocorticoid treatment: a pilot study in patients with polymyalgia rheumatica Ann N Y Acad Sci 1193 2010 160 163
    • (2010) Ann N y Acad Sci , vol.1193 , pp. 160-163
    • Cimmino, M.A.1    Andraghetti, G.2    Briatore, L.3    Salani, B.4    Parodi, M.5    Cutolo, M.6
  • 59
    • 0030032754 scopus 로고    scopus 로고
    • Genomic structure and promoter analysis of the human obese gene
    • D.W. Gong, S. Bi, R.E. Pratley, and B.D. Weintraub Genomic structure and promoter analysis of the human obese gene J Biol Chem 271 1996 3971 3974
    • (1996) J Biol Chem , vol.271 , pp. 3971-3974
    • Gong, D.W.1    Bi, S.2    Pratley, R.E.3    Weintraub, B.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.