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Volumn 8, Issue 11, 2013, Pages

KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons

Author keywords

[No Author keywords available]

Indexed keywords

KHSRP PROTEIN, HUMAN; MESSENGER RNA; NEUROMODULIN; PROTEIN BINDING; RNA BINDING PROTEIN; TRANSACTIVATOR PROTEIN;

EID: 84893654613     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079255     Document Type: Article
Times cited : (43)

References (50)
  • 2
    • 0034927379 scopus 로고    scopus 로고
    • Protein synthesis at synaptic sites on dendrites
    • DOI 10.1146/annurev.neuro.24.1.299
    • Steward O, Schuman EM (2001) Protein synthesis at synaptic sites on dendrites. Annu Rev Neurosci 24: 299-325. (Pubitemid 32695231)
    • (2001) Annual Review of Neuroscience , vol.24 , pp. 299-325
    • Steward, O.1    Schuman, E.M.2
  • 3
    • 33746206334 scopus 로고    scopus 로고
    • RNA trafficking and local protein synthesis in dendrites: An overview
    • Martin KC, Zukin RS (2006) RNA trafficking and local protein synthesis in dendrites: an overview. J Neurosci 26: 7131-7134.
    • (2006) J Neurosci , vol.26 , pp. 7131-7134
    • Martin, K.C.1    Zukin, R.S.2
  • 4
    • 77950864433 scopus 로고    scopus 로고
    • Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration
    • Yoo S, van Niekerk EA, Merianda TT, Twiss JL (2010) Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration. Exp Neurol 223: 19-27.
    • (2010) Exp Neurol , vol.223 , pp. 19-27
    • Yoo, S.1    Van Niekerk, E.A.2    Merianda, T.T.3    Twiss, J.L.4
  • 5
    • 38849117246 scopus 로고    scopus 로고
    • RNA-protein interactions and control of mRNA stability in neurons
    • DOI 10.1002/jnr.21473
    • Bolognani F, Perrone-Bizzozero NI (2008) RNA-protein interactions and control of mRNA stability in neurons. J Neurosci Res 86: 481-489. (Pubitemid 351204460)
    • (2008) Journal of Neuroscience Research , vol.86 , Issue.3 , pp. 481-489
    • Bolognani, F.1    Perrone-Bizzozero, N.I.2
  • 6
    • 0023058975 scopus 로고
    • A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
    • Shaw G, Kamen R (1986) A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46: 659-667.
    • (1986) Cell , vol.46 , pp. 659-667
    • Shaw, G.1    Kamen, R.2
  • 7
    • 0022539191 scopus 로고
    • A protein induced during nerve growth (GAP-43) is a major component of growth-cone membranes
    • Skene JH, Jacobson RD, Snipes GJ, McGuire CB, Norden JJ, et al. (1986) A protein induced during nerve growth (GAP-43) is a major component of growthcone membranes. Science 233: 783-786. (Pubitemid 16016233)
    • (1986) Science , vol.233 , Issue.4765 , pp. 783-786
    • Pate, S.J.H.1    Jacobson, R.D.2    Jackson, S.G.3
  • 8
    • 0026322490 scopus 로고
    • The expression of GAP-43 in relation to neuronal growth and plasticity: When, where, how, and why?
    • Benowitz LI, Perrone-Bizzozero NI (1991) The expression of GAP-43 in relation to neuronal growth and plasticity: when, where, how, and why? Prog Brain Res 89: 69-87.
    • (1991) Prog Brain Res , vol.89 , pp. 69-87
    • Benowitz, L.I.1    Perrone-Bizzozero, N.I.2
  • 10
    • 0028853240 scopus 로고
    • Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43
    • Strittmatter SM, Fankhauser C, Huang PL, Mashimo H, Fishman MC (1995) Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell 80: 445-452.
    • (1995) Cell , vol.80 , pp. 445-452
    • Strittmatter, S.M.1    Fankhauser, C.2    Huang, P.L.3    Mashimo, H.4    Fishman, M.C.5
  • 11
    • 14844316655 scopus 로고    scopus 로고
    • Hippocampal-dependent memory is impaired in heterozygous GAP-43 knockout mice
    • DOI 10.1002/hipo.20045
    • Rekart JL, Meiri K, Routtenberg A (2005) Hippocampal-dependent memory is impaired in heterozygous GAP-43 knockout mice. Hippocampus 15: 1-7. (Pubitemid 40340236)
    • (2005) Hippocampus , vol.15 , Issue.1 , pp. 1-7
    • Rekart, J.L.1    Meiri, K.2    Routtenberg, A.3
  • 12
    • 0028866034 scopus 로고
    • Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice
    • Aigner L, Arber S, Kapfhammer JP, Laux T, Schneider C, et al. (1995) Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell 83: 269-278.
    • (1995) Cell , vol.83 , pp. 269-278
    • Aigner, L.1    Arber, S.2    Kapfhammer, J.P.3    Laux, T.4    Schneider, C.5
  • 13
    • 0037008694 scopus 로고    scopus 로고
    • Poly(A) tail length-dependent stabilization of GAP-43 mRNA by the RNA-binding protein HuD
    • DOI 10.1074/jbc.M201982200
    • Beckel-Mitchener AC, Miera A, Keller R, Perrone-Bizzozero NI (2002) Poly(A) tail length-dependent stabilization of GAP-43 mRNA by the RNA-binding protein HuD. J Biol Chem 277: 27996-28002. (Pubitemid 34966749)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.31 , pp. 27996-28002
    • Beckel-Mitchener, A.C.1    Miera, A.2    Keller, R.3    Perrone-Bizzozero, N.I.4
  • 15
    • 33645104974 scopus 로고    scopus 로고
    • In vivo post-transcriptional regulation of GAP-43 mRNA by overexpression of the RNA-binding protein HuD
    • Bolognani F, Tanner DC, Merhege M, Deschenes-Furry J, Jasmin B, et al. (2006) In vivo post-transcriptional regulation of GAP-43 mRNA by overexpression of the RNA-binding protein HuD. J Neurochem 96: 790-801.
    • (2006) J Neurochem , vol.96 , pp. 790-801
    • Bolognani, F.1    Tanner, D.C.2    Merhege, M.3    Deschenes-Furry, J.4    Jasmin, B.5
  • 17
    • 0035068577 scopus 로고    scopus 로고
    • Overexpression of HuD accelerates neurite outgrowth and increases GAP-43 mRNA expression in cortical neurons and retinoic acid-induced embryonic stem cells in vitro
    • DOI 10.1006/exnr.2000.7599
    • Anderson KD, Sengupta J, Morin M, Neve RL, Valenzuela CF, et al. (2001) Overexpression of HuD accelerates neurite outgrowth and increases GAP-43 mRNA expression in cortical neurons and retinoic acid-induced embryonic stem cells in vitro. Exp Neurol 168: 250-258. (Pubitemid 32289761)
    • (2001) Experimental Neurology , vol.168 , Issue.2 , pp. 250-258
    • Anderson, K.D.1    Sengupta, J.2    Morin, M.3    Neve, R.L.4    Valenzuela, C.F.5    Perrone-Bizzozero, N.I.6
  • 18
    • 84857017739 scopus 로고    scopus 로고
    • Increased expression of axogenesis-related genes and mossy fibre length in dentate granule cells from adult HuD overexpressor mice
    • Perrone-Bizzozero NI, Tanner DC, Mounce J, Bolognani F (2011) Increased expression of axogenesis-related genes and mossy fibre length in dentate granule cells from adult HuD overexpressor mice. ASN Neuro 3: 259-270.
    • (2011) ASN Neuro , vol.3 , pp. 259-270
    • Perrone-Bizzozero, N.I.1    Tanner, D.C.2    Mounce, J.3    Bolognani, F.4
  • 19
    • 0029956656 scopus 로고    scopus 로고
    • The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators
    • DOI 10.1074/jbc.271.49.31679
    • Davis-Smyth T, Duncan RC, Zheng T, Michelotti G, Levens D (1996) The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators. J Biol Chem 271: 31679-31687. (Pubitemid 26408632)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.49 , pp. 31679-31687
    • Davis-Smyth, T.1    Duncan, R.C.2    Zheng, T.3    Michelotti, G.4    Levens, D.5
  • 20
    • 0030969572 scopus 로고    scopus 로고
    • A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer
    • Min H, Turck CW, Nikolic JM, Black DL (1997) A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev 11: 1023-1036. (Pubitemid 27199881)
    • (1997) Genes and Development , vol.11 , Issue.8 , pp. 1023-1036
    • Min, H.1    Turck, C.W.2    Nikolic, J.M.3    Black, D.L.4
  • 21
    • 0036724607 scopus 로고    scopus 로고
    • Molecular characterization of MARTA1, a protein interacting with the dendritic targeting element of MAP2 mRNAs
    • DOI 10.1046/j.1471-4159.2002.01058.x
    • Rehbein M, Wege K, Buck F, Schweizer M, Richter D, et al. (2002) Molecular characterization of MARTA1, a protein interacting with the dendritic targeting element of MAP2 mRNAs. J Neurochem 82: 1039-1046. (Pubitemid 34966616)
    • (2002) Journal of Neurochemistry , vol.82 , Issue.5 , pp. 1039-1046
    • Rehbein, M.1    Wege, K.2    Buck, F.3    Schweizer, M.4    Richter, D.5    Kindler, S.6
  • 22
    • 0037033786 scopus 로고    scopus 로고
    • A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons
    • DOI 10.1083/jcb.200105133
    • Gu W, Pan F, Zhang H, Bassell GJ, Singer RH (2002) A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons. J Cell Biol 156: 41-51. (Pubitemid 34846934)
    • (2002) Journal of Cell Biology , vol.156 , Issue.1 , pp. 41-51
    • Gu, W.1    Pan, F.2    Zhang, H.3    Bassell, G.J.4    Singer, R.H.5
  • 23
    • 67649277689 scopus 로고    scopus 로고
    • The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs
    • Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, et al. (2009) The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 459: 1010-1014.
    • (2009) Nature , vol.459 , pp. 1010-1014
    • Trabucchi, M.1    Briata, P.2    Garcia-Mayoral, M.3    Haase, A.D.4    Filipowicz, W.5
  • 24
    • 2942612333 scopus 로고    scopus 로고
    • A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery
    • DOI 10.1016/j.molcel.2004.05.002, PII S1097276504002709
    • Gherzi R, Lee KY, Briata P, Wegmuller D, Moroni C, et al. (2004) A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol Cell 14: 571-583. (Pubitemid 38739081)
    • (2004) Molecular Cell , vol.14 , Issue.5 , pp. 571-583
    • Gherzi, R.1    Lee, K.-Y.2    Briata, P.3    Wegmuller, D.4    Moroni, C.5    Karin, M.6    Chen, C.-Y.7
  • 26
    • 24144499990 scopus 로고    scopus 로고
    • Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR
    • DOI 10.1093/nar/gki797
    • Linker K, Pautz A, Fechir M, Hubrich T, Greeve J, et al. (2005) Involvement of KSRP in the post-transcriptional regulation of human iNOS expressioncomplex interplay of KSRP with TTP and HuR. Nucleic Acids Res 33: 4813-4827. (Pubitemid 41418881)
    • (2005) Nucleic Acids Research , vol.33 , Issue.15 , pp. 4813-4827
    • Linker, K.1    Pautz, A.2    Fechir, M.3    Hubrich, T.4    Greeve, J.5    Kleinert, H.6
  • 27
    • 84865862707 scopus 로고    scopus 로고
    • KSRP: A checkpoint for inflammatory cytokine production in astrocytes
    • Li X, Lin WJ, Chen CY, Si Y, Zhang X, et al. (2012) KSRP: a checkpoint for inflammatory cytokine production in astrocytes. Glia 60: 1773-1784.
    • (2012) Glia , vol.60 , pp. 1773-1784
    • Li, X.1    Lin, W.J.2    Chen, C.Y.3    Si, Y.4    Zhang, X.5
  • 28
    • 1842529308 scopus 로고    scopus 로고
    • Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay
    • Lu JY, Schneider RJ (2004) Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay. J Biol Chem 279: 12974-12979.
    • (2004) J Biol Chem , vol.279 , pp. 12974-12979
    • Lu, J.Y.1    Schneider, R.J.2
  • 29
    • 84874203616 scopus 로고    scopus 로고
    • Axonally synthesized beta-actin and GAP-43 proteins support distinct modes of axonal growth
    • Donnelly CJ, Park M, Spillane M, Yoo S, Pacheco A, et al. (2013) Axonally synthesized beta-actin and GAP-43 proteins support distinct modes of axonal growth. J Neurosci 33: 3311-3322.
    • (2013) J Neurosci , vol.33 , pp. 3311-3322
    • Donnelly, C.J.1    Park, M.2    Spillane, M.3    Yoo, S.4    Pacheco, A.5
  • 30
    • 0029868063 scopus 로고    scopus 로고
    • Role of highly conserved pyrimidine-rich sequences in the 39 untranslated region of the GAP-43 mRNA in mRNA stability and RNA-protein interactions
    • Kohn DT, Tsai KC, Cansino VV, Neve RL, Perrone-Bizzozero NI (1996) Role of highly conserved pyrimidine-rich sequences in the 39 untranslated region of the GAP-43 mRNA in mRNA stability and RNA-protein interactions. Brain Res Mol Brain Res 36: 240-250.
    • (1996) Brain Res Mol Brain Res , vol.36 , pp. 240-250
    • Kohn, D.T.1    Tsai, K.C.2    Cansino, V.V.3    Neve, R.L.4    Perrone-Bizzozero, N.I.5
  • 31
    • 0031037486 scopus 로고    scopus 로고
    • Post-transcriptional regulation of the GAP-43 gene by specific sequences in the 3' untranslated region of the mRNA
    • Tsai KC, Cansino VV, Kohn DT, Neve RL, Perrone-Bizzozero NI (1997) Post-transcriptional regulation of the GAP-43 gene by specific sequences in the 3′ untranslated region of the mRNA. J Neurosci 17: 1950-1958. (Pubitemid 27106754)
    • (1997) Journal of Neuroscience , vol.17 , Issue.6 , pp. 1950-1958
    • Tsai, K.C.1    Cansino, V.V.2    Kohn, D.T.3    Neve, R.L.4    Perrone-Bizzozero, N.I.5
  • 32
    • 3242658929 scopus 로고    scopus 로고
    • A modified quantitative EMSA and its application in the study of RNA-protein interactions
    • DOI 10.1016/j.jbbm.2004.03.008, PII S0165022X04001253
    • Li Y, Jiang Z, Chen H, Ma WJ (2004) A modified quantitative EMSA and its application in the study of RNA-protein interactions. J Biochem Biophys Methods 60: 85-96. (Pubitemid 38953054)
    • (2004) Journal of Biochemical and Biophysical Methods , vol.60 , Issue.2 , pp. 85-96
    • Li, Y.1    Jiang, Z.2    Chen, H.3    Ma, W.-J.4
  • 33
    • 27944508215 scopus 로고    scopus 로고
    • CLIP: A method for identifying protein-RNA interaction sites in living cells
    • DOI 10.1016/j.ymeth.2005.07.018, PII S1046202305001787, Post-transcriptional Regulation of Gene Expression
    • Ule J, Jensen K, Mele A, Darnell RB (2005) CLIP: a method for identifying protein-RNA interaction sites in living cells. Methods 37: 376-386. (Pubitemid 41682508)
    • (2005) Methods , vol.37 , Issue.4 , pp. 376-386
    • Ule, J.1    Jensen, K.2    Mele, A.3    Darnell, R.B.4
  • 34
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi SW, Zang JB, Mele A, Darnell RB (2009) Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460: 479-486.
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 35
    • 79961159449 scopus 로고    scopus 로고
    • Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection
    • Lin WJ, Zheng X, Lin CC, Tsao J, Zhu X, et al. (2011) Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection. Mol Cell Biol 31: 3196-3207.
    • (2011) Mol Cell Biol , vol.31 , pp. 3196-3207
    • Lin, W.J.1    Zheng, X.2    Lin, C.C.3    Tsao, J.4    Zhu, X.5
  • 36
    • 0033555659 scopus 로고    scopus 로고
    • ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system
    • Ford LP, Watson J, Keene JD, Wilusz J (1999) ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system. Genes Dev 13: 188-201. (Pubitemid 29061949)
    • (1999) Genes and Development , vol.13 , Issue.2 , pp. 188-201
    • Ford, L.P.1    Watson, J.2    Keene, J.D.3    Wilusz, J.4
  • 37
    • 0035710746 scopus 로고    scopus 로고
    • -Delta Delta CT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 38
    • 77956114374 scopus 로고    scopus 로고
    • MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1
    • Smrt RD, Szulwach KE, Pfeiffer RL, Li X, Guo W, et al. (2010) MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1. Stem Cells 28: 1060-1070.
    • (2010) Stem Cells , vol.28 , pp. 1060-1070
    • Smrt, R.D.1    Szulwach, K.E.2    Pfeiffer, R.L.3    Li, X.4    Guo, W.5
  • 39
    • 35848966583 scopus 로고    scopus 로고
    • Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity
    • DOI 10.1007/s11064-007-9388-8
    • Bolognani F, Tanner DC, Nixon S, Okano HJ, Okano H, et al. (2007) Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity. Neurochem Res 32: 2142-2151. (Pubitemid 350059858)
    • (2007) Neurochemical Research , vol.32 , Issue.12 , pp. 2142-2151
    • Bolognani, F.1    Tanner, D.C.2    Nixon, S.3    Okano, H.J.4    Okano, H.5    Perrone-Bizzozero, N.I.6
  • 41
    • 0742305338 scopus 로고    scopus 로고
    • Differentiation-induced Colocalization of the KH-type Splicing Regulatory Protein with Polypyrimidine Tract Binding Protein and the c-src Pre-mRNA
    • DOI 10.1091/mbc.E03-09-0692
    • Hall MP, Huang S, Black DL (2004) Differentiation-induced colocalization of the KH-type splicing regulatory protein with polypyrimidine tract binding protein and the c-src pre-mRNA. Mol Biol Cell 15: 774-786. (Pubitemid 38146492)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.2 , pp. 774-786
    • Hall, M.P.1    Huang, S.2    Black, D.L.3
  • 42
    • 84883740694 scopus 로고    scopus 로고
    • A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 39 untranslated region AU-rich regulatory element
    • Apr doi:10.1111/jnc.12266. [Epub ahead of print]
    • Yoo S, Kim HH, Kim P, Donnelly CJ, Kalinski AL, et al. (2013) A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 39 untranslated region AU-rich regulatory element. J Neurochem Apr 15. doi:10.1111/jnc.12266. [Epub ahead of print]
    • (2013) J Neurochem , pp. 15
    • Yoo, S.1    Kim, H.H.2    Kim, P.3    Donnelly, C.J.4    Kalinski, A.L.5
  • 43
    • 36849088518 scopus 로고    scopus 로고
    • ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription
    • DOI 10.1128/MCB.00972-07
    • Pan F, Huttelmaier S, Singer RH, Gu W (2007) ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription. Mol Cell Biol 27: 8340-8351. (Pubitemid 350234245)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.23 , pp. 8340-8351
    • Pan, F.1    Huttelmaier, S.2    Singer, R.H.3    Gu, W.4
  • 44
    • 81255134129 scopus 로고    scopus 로고
    • Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity
    • Donnelly CJ, Willis DE, Xu M, Tep C, Jiang C, et al. (2011) Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity. EMBO J 30: 4665-4677.
    • (2011) EMBO J , vol.30 , pp. 4665-4677
    • Donnelly, C.J.1    Willis, D.E.2    Xu, M.3    Tep, C.4    Jiang, C.5
  • 46
  • 47
    • 38849088603 scopus 로고    scopus 로고
    • KH-type splicing regulatory protein interacts with survival motor neuron protein and is misregulated in spinal muscular atrophy
    • DOI 10.1093/hmg/ddm327
    • Tadesse H, Deschenes-Furry J, Boisvenue S, Cote J (2008) KH-type splicing regulatory protein interacts with survival motor neuron protein and is misregulated in spinal muscular atrophy. Hum Mol Gen 17: 506-524. (Pubitemid 351201766)
    • (2008) Human Molecular Genetics , vol.17 , Issue.4 , pp. 506-524
    • Tadesse, H.1    Deschenes-Furry, J.2    Boisvenue, S.3    Cote, J.4
  • 49
    • 79952390939 scopus 로고    scopus 로고
    • The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons
    • Fallini C, Zhang H, Su Y, Silani V, Singer RH, et al. (2011) The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons. J Neurosci 31: 3914-3925.
    • (2011) J Neurosci , vol.31 , pp. 3914-3925
    • Fallini, C.1    Zhang, H.2    Su, Y.3    Silani, V.4    Singer, R.H.5
  • 50
    • 78651094423 scopus 로고    scopus 로고
    • HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects
    • Hubers L, Valderrama-Carvajal H, Laframboise J, Timbers J, Sanchez G, et al. (2011) HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects. Hum Mol Gen 20: 553-579.
    • (2011) Hum Mol Gen , vol.20 , pp. 553-579
    • Hubers, L.1    Valderrama-Carvajal, H.2    Laframboise, J.3    Timbers, J.4    Sanchez, G.5


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