Knockdown of LGR5 suppresses the proliferation of glioma cells in vitro and in vivo

Neurosurgery

Volumn 74, Issue 2, 2014, Pages

  Parry, Phillip V ^a   Engh, Johnathan A ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR 5; RECEPTOR; UNCLASSIFIED DRUG;

CELL PROLIFERATION; GENE SILENCING; GLIOMA CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ASTROCYTES; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE KNOCKDOWN TECHNIQUES; GLIOMA; HUMANS; MICE; NEOPLASM TRANSPLANTATION; RECEPTORS, G-PROTEIN-COUPLED; TRANSPLANTATION, HETEROLOGOUS;

EID: 84893614015     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.neu.0000442976.61335.f6     Document Type: Note

References (5)

1. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK. WHO Classification of Tumours of the Central Nervous System. 4th ed. Lyon, France: IARC Press; 2007.
2. Barker N, van Ed JH, Kuipers J, Kujala P, et al. Identification of stem cells in small intestine and colon by marker gene LGR5. Nature. 2007;449(7165): 1003-1007.
3. Barker N, Clevers H. Leucine-rich repeat containing G-protein-coupled receptors as markers of adult stem cells. Gastroenterology. 2010;138(5):1681- 1696.
4. 1ve stem/progenitor cells contribute to nephron formation during kidney development. Cell Rep. 2010;2(3):540-552.
5. Wang D, Zhou J, Cungang F, Jiao F, et al. Knockdown of LGR5 suppresses the proliferation of glioma cells in vitro and in vivo. Oncol Rep. 2013;31 (1):41-49.