Hepatic cytochrome P450s play a major role in monocrotaline-induced renal toxicity in mice

Acta Pharmacologica Sinica

Volumn 35, Issue 2, 2014, Pages 292-300

  Yao, Jun ^a   Li, Cheng Gang ^a   Gong, Li Kun ^a   Feng, Chen Chen ^a   Li, Chun Zhu ^a   Gao, Man ^a   Luan, Yang ^a   Qi, Xin Ming ^a   Ren, Jin ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CREATININE; CYTOCHROME P450; CYTOCHROME P450 3A; CYTOCHROME P450 REDUCTASE; HYALURONIC ACID; MONOCROTALINE;

ANIMAL EXPERIMENT; ARTICLE; BILE; BLOOD; CREATININE BLOOD LEVEL; DISEASE SEVERITY; KIDNEY; LIQUID CHROMATOGRAPHY; LIVER; LIVER TOXICITY; LUNG; METABOLIC ACTIVATION; MOUSE; NEPHROTOXICITY; NONHUMAN; TANDEM MASS SPECTROMETRY; UREA NITROGEN BLOOD LEVEL;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; KIDNEY; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCROTALINE; NADPH-FERRIHEMOPROTEIN REDUCTASE;

EID: 84893589590     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.145     Document Type: Article

References (0)