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Volumn 6, Issue 1, 2014, Pages 63-75

New modalities of cancer treatment for NSCLC: Focus on immunotherapy

Author keywords

Immunotherapy; Ipilimumab; Lung cancer; Nivolumab; Nursing; Vaccination

Indexed keywords


EID: 84893568071     PISSN: None     EISSN: 11791322     Source Type: Journal    
DOI: 10.2147/CMAR.S57550     Document Type: Review
Times cited : (67)

References (87)
  • 1
    • 84893627594 scopus 로고    scopus 로고
    • American Cancer Society. Available from: Updated 2013. Accessed October 8, 2013
    • American Cancer Society. Cancer facts and figures 2013. Available from: http://www.cancer.org/research/cancerfactsstatistics/cancerfacts figures2013/index. Updated 2013. Accessed October 8, 2013.
    • Cancer facts and figures 2013.
  • 2
    • 44249086425 scopus 로고    scopus 로고
    • Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship
    • Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc. 2008;83(5):584-594.
    • (2008) Mayo Clin Proc. , vol.83 , Issue.5 , pp. 584-594
    • Molina, J.R.1    Yang, P.2    Cassivi, S.D.3    Schild, S.E.4    Adjei, A.A.5
  • 3
    • 84871351824 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology (NCCN Guidelines®). Version 2.2013. Available from: Updated 2013. Accessed October 8, 2013
    • National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology (NCCN Guidelines®). Non-small cell lung cancer. Version 2.2013. Available from: http://www.nccn.com. Updated 2013. Accessed October 8, 2013.
    • Non-small cell lung cancer.
  • 4
    • 19844375720 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in non-small-cell lung cancer: Implications for treatment and tumor biology
    • Jänne PA, Engelman JA, Johnson BE. Epidermal growth factor receptor mutations in non-small-cell lung cancer: implications for treatment and tumor biology. J Clin Oncol. 2005;23(14):3227-3234.
    • (2005) J Clin Oncol. , vol.23 , Issue.14 , pp. 3227-3234
    • Jänne, P.A.1    Engelman, J.A.2    Johnson, B.E.3
  • 6
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR, etal. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med. 2010;363(18): 1693-1703.
    • (2010) N Engl J Med. , vol.363 , Issue.18 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 7
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Jänne PA, Lee JC, etal. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004;304(5676):1497-1500.
    • (2004) Science. , vol.304 , Issue.5676 , pp. 1497-1500
    • Paez, J.G.1    Jänne, P.A.2    Lee, J.C.3
  • 8
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
    • Shigematsu H, Lin L, Takahashi T, etal. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst. 2005;97(5):339-346.
    • (2005) J Natl Cancer Inst. , vol.97 , Issue.5 , pp. 339-346
    • Shigematsu, H.1    Lin, L.2    Takahashi, T.3
  • 9
    • 84867395679 scopus 로고    scopus 로고
    • EML4-ALK testing in non-small cell carcinomas of the lung: A review with recommendations
    • Thunnissen E, Bubendorf L, Dietel M, etal. EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations. Virchows Arch. 2012;461(3):245-257.
    • (2012) Virchows Arch. , vol.461 , Issue.3 , pp. 245-257
    • Thunnissen, E.1    Bubendorf, L.2    Dietel, M.3
  • 10
    • 79952613370 scopus 로고    scopus 로고
    • Systematic review of medical treatment in melanoma: Current status and future prospects
    • Garbe C, Eigentler TK, Keilholz U, Hauschild A, Kirkwood JM. Systematic review of medical treatment in melanoma: current status and future prospects. Oncologist. 2011;16(1):5-24.
    • (2011) Oncologist. , vol.16 , Issue.1 , pp. 5-24
    • Garbe, C.1    Eigentler, T.K.2    Keilholz, U.3    Hauschild, A.4    Kirkwood, J.M.5
  • 11
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012;12(4):252-264.
    • (2012) Nat Rev Cancer. , vol.12 , Issue.4 , pp. 252-264
    • Pardoll, D.M.1
  • 12
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, etal. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366(26): 2443-2454.
    • (2012) N Engl J Med. , vol.366 , Issue.26 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 13
    • 84879777241 scopus 로고    scopus 로고
    • Nivolumab plus ipilimumab in advanced melanoma
    • Wolchok JD, Kluger H, Callahan MK, etal. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med. 2013;369(2):122-133.
    • (2013) N Engl J Med. , vol.369 , Issue.2 , pp. 122-133
    • Wolchok, J.D.1    Kluger, H.2    Callahan, M.K.3
  • 14
    • 75249100054 scopus 로고    scopus 로고
    • Ipilimumab monotherapy in patients with pretreated advanced melanoma: A randomised, double-blind, multicentre, phase 2, dose-ranging study
    • Wolchok JD, Neyns B, Linette G, etal. Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol. 2010;11(2):155-164.
    • (2010) Lancet Oncol. , vol.11 , Issue.2 , pp. 155-164
    • Wolchok, J.D.1    Neyns, B.2    Linette, G.3
  • 15
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science. 2011;331(6024):1565-1570.
    • (2011) Science. , vol.331 , Issue.6024 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 16
    • 34347323902 scopus 로고    scopus 로고
    • Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: A meta-analysis
    • Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM. Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet. 2007;370(9581):59-67.
    • (2007) Lancet. , vol.370 , Issue.9581 , pp. 59-67
    • Grulich, A.E.1    van Leeuwen, M.T.2    Falster, M.O.3    Vajdic, C.M.4
  • 17
    • 49249089425 scopus 로고    scopus 로고
    • Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways
    • Fife BT, Bluestone JA. Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways. Immunol Rev. 2008;224:166-182.
    • (2008) Immunol Rev. , vol.224 , pp. 166-182
    • Fife, B.T.1    Bluestone, J.A.2
  • 18
    • 34748870776 scopus 로고    scopus 로고
    • Lack and restoration of sensitivity of lung cancer cells to cellular attack with special reference to expression of human leukocyte antigen class I and/or major histocompatibility complex class I chain related molecules A/B
    • Baba T, Hanagiri T, Ichiki Y, etal. Lack and restoration of sensitivity of lung cancer cells to cellular attack with special reference to expression of human leukocyte antigen class I and/or major histocompatibility complex class I chain related molecules A/B. Cancer Sci. 2007;98(11):1795-1802.
    • (2007) Cancer Sci. , vol.98 , Issue.11 , pp. 1795-1802
    • Baba, T.1    Hanagiri, T.2    Ichiki, Y.3
  • 19
    • 34249907598 scopus 로고    scopus 로고
    • Cytokine production of lung cancer cell lines: Correlation between their production and the inflammatory/immunological responses both in vivo and in vitro
    • Fukuyama T, Ichiki Y, Yamada S, etal. Cytokine production of lung cancer cell lines: Correlation between their production and the inflammatory/immunological responses both in vivo and in vitro. Cancer Sci. 2007;98(7):1048-1054.
    • (2007) Cancer Sci. , vol.98 , Issue.7 , pp. 1048-1054
    • Fukuyama, T.1    Ichiki, Y.2    Yamada, S.3
  • 20
    • 84864954385 scopus 로고    scopus 로고
    • Lung cancer: A classic example of tumor escape and progression while providing opportunities for immunological intervention
    • Jadus MR, Natividad J, Mai A, etal. Lung cancer: a classic example of tumor escape and progression while providing opportunities for immunological intervention. Clin Dev Immunol. 2012;2012: 160724.
    • (2012) Clin Dev Immunol. , pp. 160724
    • Jadus, M.R.1    Natividad, J.2    Mai, A.3
  • 21
    • 0030933337 scopus 로고    scopus 로고
    • Human lung carcinomas express Fas ligand
    • Niehans GA, Brunner T, Frizelle SP, etal. Human lung carcinomas express Fas ligand. Cancer Res. 1997;57(6):1007-1012.
    • (1997) Cancer Res. , vol.57 , Issue.6 , pp. 1007-1012
    • Niehans, G.A.1    Brunner, T.2    Frizelle, S.P.3
  • 22
    • 33845590308 scopus 로고    scopus 로고
    • Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients
    • Petersen RP, Campa MJ, Sperlazza J, etal. Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients. Cancer. 2006;107(12):2866-2872.
    • (2006) Cancer. , vol.107 , Issue.12 , pp. 2866-2872
    • Petersen, R.P.1    Campa, M.J.2    Sperlazza, J.3
  • 23
    • 77951877847 scopus 로고    scopus 로고
    • Tumor-infiltrating Foxp3+ regulatory T cells are correlated with cyclooxygenase-2 expression and are associated with recurrence in resected non-small cell lung cancer
    • Shimizu K, Nakata M, Hirami Y, Yukawa T, Maeda A, Tanemoto K. Tumor-infiltrating Foxp3+ regulatory T cells are correlated with cyclooxygenase-2 expression and are associated with recurrence in resected non-small cell lung cancer. J Thorac Oncol. 2010;5(5):585-590.
    • (2010) J Thorac Oncol. , vol.5 , Issue.5 , pp. 585-590
    • Shimizu, K.1    Nakata, M.2    Hirami, Y.3    Yukawa, T.4    Maeda, A.5    Tanemoto, K.6
  • 24
    • 85020908157 scopus 로고    scopus 로고
    • Princeton, NJ, USA: Bristol-Myers Squibb Company
    • Yervoy® (ipilimumab) [package insert]. Princeton, NJ, USA: Bristol-Myers Squibb Company; 2013.
    • (2013) Yervoy® (ipilimumab) [package insert].
  • 25
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O'Day SJ, McDermott DF, etal. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711-723.
    • (2010) N Engl J Med. , vol.363 , Issue.8 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 27
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • Kantoff PW, Higano CS, Shore ND, etal. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med. 2010;363(5): 411-422.
    • (2010) N Engl J Med. , vol.363 , Issue.5 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 28
    • 52649163840 scopus 로고    scopus 로고
    • Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer
    • Al-Shibli KI, Donnem T, Al-Saad S, Persson M, Bremnes RM, Busund LT. Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer. Clin Cancer Res. 2008;14(16): 5220-5227.
    • (2008) Clin Cancer Res. , vol.14 , Issue.16 , pp. 5220-5227
    • Al-Shibli, K.I.1    Donnem, T.2    Al-Saad, S.3    Persson, M.4    Bremnes, R.M.5    Busund, L.T.6
  • 29
    • 52449102477 scopus 로고    scopus 로고
    • Long-term survival for patients with non-small-cell lung cancer with intratumoral lymphoid structures
    • Dieu-Nosjean MC, Antoine M, Danel C, etal. Long-term survival for patients with non-small-cell lung cancer with intratumoral lymphoid structures. J Clin Oncol. 2008;26(27):4410-4417.
    • (2008) J Clin Oncol. , vol.26 , Issue.27 , pp. 4410-4417
    • Dieu-Nosjean, M.C.1    Antoine, M.2    Danel, C.3
  • 30
    • 31444439350 scopus 로고    scopus 로고
    • Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small-cell lung carcinoma
    • Hiraoka K, Miyamoto M, Cho Y, etal. Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small-cell lung carcinoma. Br J Cancer. 2006;94(2):275-280.
    • (2006) Br J Cancer. , vol.94 , Issue.2 , pp. 275-280
    • Hiraoka, K.1    Miyamoto, M.2    Cho, Y.3
  • 31
    • 76149124214 scopus 로고    scopus 로고
    • A high number of CD8+ T cells infiltrated in NSCLC tissues is associated with a favorable prognosis
    • Zhuang X, Xia X, Wang C, etal. A high number of CD8+ T cells infiltrated in NSCLC tissues is associated with a favorable prognosis. Appl Immunohistochem Mol Morphol. 2010;18(1):24-28.
    • (2010) Appl Immunohistochem Mol Morphol. , vol.18 , Issue.1 , pp. 24-28
    • Zhuang, X.1    Xia, X.2    Wang, C.3
  • 32
    • 0035384386 scopus 로고    scopus 로고
    • The prognostic value of natural killer cell infiltration in resected pulmonary adenocarcinoma
    • Takanami I, Takeuchi K, Giga M. The prognostic value of natural killer cell infiltration in resected pulmonary adenocarcinoma. J Thorac Cardiovasc Surg. 2001;121(6):1058-1063.
    • (2001) J Thorac Cardiovasc Surg. , vol.121 , Issue.6 , pp. 1058-1063
    • Takanami, I.1    Takeuchi, K.2    Giga, M.3
  • 33
    • 0036136050 scopus 로고    scopus 로고
    • Prognostic significance of tumor infiltrating natural killer cells subset CD57 in patients with squamous cell lung cancer
    • Villegas FR, Coca S, Villarrubia VG, etal. Prognostic significance of tumor infiltrating natural killer cells subset CD57 in patients with squamous cell lung cancer. Lung Cancer. 2002;35(1):23-28.
    • (2002) Lung Cancer. , vol.35 , Issue.1 , pp. 23-28
    • Villegas, F.R.1    Coca, S.2    Villarrubia, V.G.3
  • 34
    • 84862236855 scopus 로고    scopus 로고
    • Immune alterations and emerging immunotherapeutic approaches in lung cancer
    • Dasanu CA, Sethi N, Ahmed N. Immune alterations and emerging immunotherapeutic approaches in lung cancer. Expert Opin Biol Ther. 2012;12(7):923-937.
    • (2012) Expert Opin Biol Ther. , vol.12 , Issue.7 , pp. 923-937
    • Dasanu, C.A.1    Sethi, N.2    Ahmed, N.3
  • 35
    • 80051675837 scopus 로고    scopus 로고
    • Profound coordinated alterations of intratumoral natural killer cell phenotype and function in lung carcinoma
    • Platonova S, Cherfils-Vicini J, Damotte D, etal. Profound coordinated alterations of intratumoral natural killer cell phenotype and function in lung carcinoma. Cancer Res. 2011;71(16):5412-5422.
    • (2011) Cancer Res. , vol.71 , Issue.16 , pp. 5412-5422
    • Platonova, S.1    Cherfils-Vicini, J.2    Damotte, D.3
  • 36
    • 79959864289 scopus 로고    scopus 로고
    • Non-small cell lung cancer induces an immunosuppressive phenotype of dendritic cells in tumor microenvironment by upregulating B7-H3
    • Schneider T, Hoffmann H, Dienemann H, etal. Non-small cell lung cancer induces an immunosuppressive phenotype of dendritic cells in tumor microenvironment by upregulating B7-H3. J Thorac Oncol. 2011;6(7):1162-1168.
    • (2011) J Thorac Oncol. , vol.6 , Issue.7 , pp. 1162-1168
    • Schneider, T.1    Hoffmann, H.2    Dienemann, H.3
  • 37
    • 79951770388 scopus 로고    scopus 로고
    • Foxp3(+) regulatory T cells and natural killer cells distinctly infiltrate primary tumors and draining lymph nodes in pulmonary adenocarcinoma
    • Schneider T, Kimpfler S, Warth A, etal. Foxp3(+) regulatory T cells and natural killer cells distinctly infiltrate primary tumors and draining lymph nodes in pulmonary adenocarcinoma. J Thorac Oncol. 2011;6(3): 432-438.
    • (2011) J Thorac Oncol. , vol.6 , Issue.3 , pp. 432-438
    • Schneider, T.1    Kimpfler, S.2    Warth, A.3
  • 38
    • 79956194859 scopus 로고    scopus 로고
    • Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancer
    • Wang R, Lu M, Zhang J, etal. Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancer. J Exp Clin Cancer Res. 2011;30:62.
    • (2011) J Exp Clin Cancer Res. , vol.30 , pp. 62
    • Wang, R.1    Lu, M.2    Zhang, J.3
  • 39
    • 38449107046 scopus 로고    scopus 로고
    • Macrophage expression of interleukin-10 is a prognostic factor in nonsmall cell lung cancer
    • Zeni E, Mazzetti L, Miotto D, etal. Macrophage expression of interleukin-10 is a prognostic factor in nonsmall cell lung cancer. Eur Respir J. 2007;30(4):627-632.
    • (2007) Eur Respir J. , vol.30 , Issue.4 , pp. 627-632
    • Zeni, E.1    Mazzetti, L.2    Miotto, D.3
  • 40
    • 2442661845 scopus 로고    scopus 로고
    • Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
    • Hanna N, Shepherd FA, Fossella FV, etal. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol. 2004;22(9): 1589-1597.
    • (2004) J Clin Oncol. , vol.22 , Issue.9 , pp. 1589-1597
    • Hanna, N.1    Shepherd, F.A.2    Fossella, F.V.3
  • 41
    • 28144445570 scopus 로고    scopus 로고
    • Docetaxel: A review of its use in metastatic breast cancer
    • Lyseng-Williamson KA, Fenton C. Docetaxel: a review of its use in metastatic breast cancer. Drugs. 2005;65(17):2513-2531.
    • (2005) Drugs. , vol.65 , Issue.17 , pp. 2513-2531
    • Lyseng-Williamson, K.A.1    Fenton, C.2
  • 43
    • 79959752641 scopus 로고    scopus 로고
    • Biomarkers of clinical benefit for anti-epidermal growth factor receptor agents in patients with non-small-cell lung cancer
    • Pallis AG, Fennell DA, Szutowicz E, Leighl NB, Greillier L, Dziadziuszko R. Biomarkers of clinical benefit for anti-epidermal growth factor receptor agents in patients with non-small-cell lung cancer. Br J Cancer. 2011;105(1):1-8.
    • (2011) Br J Cancer. , vol.105 , Issue.1 , pp. 1-8
    • Pallis, A.G.1    Fennell, D.A.2    Szutowicz, E.3    Leighl, N.B.4    Greillier, L.5    Dziadziuszko, R.6
  • 44
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd FA, Rodrigues PJ, Ciuleanu T, etal. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med. 2005;353(2): 123-132.
    • (2005) N Engl J Med. , vol.353 , Issue.2 , pp. 123-132
    • Shepherd, F.A.1    Rodrigues, P.J.2    Ciuleanu, T.3
  • 45
    • 84856877692 scopus 로고    scopus 로고
    • The potential for crizotinib in non-small cell lung cancer: A perspective review
    • Bang YJ. The potential for crizotinib in non-small cell lung cancer: a perspective review. Ther Adv Med Oncol. 2011;3(6):279-291.
    • (2011) Ther Adv Med Oncol. , vol.3 , Issue.6 , pp. 279-291
    • Bang, Y.J.1
  • 46
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A, Gray R, Perry MC, etal. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med. 2006;355(24):2542-2550.
    • (2006) N Engl J Med. , vol.355 , Issue.24 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3
  • 47
    • 0347364737 scopus 로고    scopus 로고
    • Melanoma associated antigen (MAGE)-A3 expression in Stages I and II non-small cell lung cancer: Results of a multi-center study
    • Sienel W, Varwerk C, Linder A, etal. Melanoma associated antigen (MAGE)-A3 expression in Stages I and II non-small cell lung cancer: results of a multi-center study. Eur J Cardiothorac Surg. 2004;25(1): 131-134.
    • (2004) Eur J Cardiothorac Surg. , vol.25 , Issue.1 , pp. 131-134
    • Sienel, W.1    Varwerk, C.2    Linder, A.3
  • 48
    • 84880755387 scopus 로고    scopus 로고
    • Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: Phase II randomized study results
    • Vansteenkiste JF, Zielinski M, Linder A, etal. Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results. J Clin Oncol. 2013;43:Abstr 7103.
    • (2013) J Clin Oncol. , vol.43 , pp. 7103
    • Vansteenkiste, J.F.1    Zielinski, M.2    Linder, A.3
  • 50
    • 84893603358 scopus 로고    scopus 로고
    • Targeting the immune system for management of NSCLC: The revival?
    • Reck M, Vansteenkiste J, Brahmer JR. Targeting the immune system for management of NSCLC: the revival? Curr Respir Care Rep. 2013;2(1):22-39.
    • (2013) Curr Respir Care Rep. , vol.2 , Issue.1 , pp. 22-39
    • Reck, M.1    Vansteenkiste, J.2    Brahmer, J.R.3
  • 51
    • 27244449289 scopus 로고    scopus 로고
    • Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer
    • Butts C, Murray N, Maksymiuk A, etal. Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer. J Clin Oncol. 2005;23(27):6674-6681.
    • (2005) J Clin Oncol. , vol.23 , Issue.27 , pp. 6674-6681
    • Butts, C.1    Murray, N.2    Maksymiuk, A.3
  • 54
    • 81255127285 scopus 로고    scopus 로고
    • Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: A controlled phase 2B trial
    • Quoix E, Ramlau R, Westeel V, etal. Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: a controlled phase 2B trial. Lancet Oncol. 2011;12(12): 1125-1133.
    • (2011) Lancet Oncol. , vol.12 , Issue.12 , pp. 1125-1133
    • Quoix, E.1    Ramlau, R.2    Westeel, V.3
  • 56
    • 33750586798 scopus 로고    scopus 로고
    • Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer
    • Nemunaitis J, Dillman RO, Schwarzenberger PO, etal. Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer. J Clin Oncol. 2006;24(29):4721-4730.
    • (2006) J Clin Oncol. , vol.24 , Issue.29 , pp. 4721-4730
    • Nemunaitis, J.1    Dillman, R.O.2    Schwarzenberger, P.O.3
  • 58
    • 41149159650 scopus 로고    scopus 로고
    • Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small-cell lung cancer
    • Neninger Vinageras E, de la Torre A, Osorio Rodríguez M, etal. Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small-cell lung cancer. J Clin Oncol. 2008;26(9): 1452-1458.
    • (2008) J Clin Oncol. , vol.26 , Issue.9 , pp. 1452-1458
    • Neninger Vinageras, E.1    de la Torre, A.2    Osorio Rodríguez, M.3
  • 62
    • 84863911486 scopus 로고    scopus 로고
    • Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: Results from a randomized, double-blind, multicenter phase II study
    • Lynch TJ, Bondarenko I, Luft A, etal. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study. J Clin Oncol. 2012;30(17):2046-2054.
    • (2012) J Clin Oncol. , vol.30 , Issue.17 , pp. 2046-2054
    • Lynch, T.J.1    Bondarenko, I.2    Luft, A.3
  • 64
    • 84877882244 scopus 로고    scopus 로고
    • Anti-programmed death-1 and anti-programmed death-ligand 1 antibodies in cancer therapy
    • Hamid O, Carvajal RD. Anti-programmed death-1 and anti-programmed death-ligand 1 antibodies in cancer therapy. Expert Opin Biol Ther. 2013;13(6):847-861.
    • (2013) Expert Opin Biol Ther. , vol.13 , Issue.6 , pp. 847-861
    • Hamid, O.1    Carvajal, R.D.2
  • 70
    • 84911181068 scopus 로고    scopus 로고
    • Sidney Kimmel Comprehensive Cancer Center. (NA_00084192). Available from: NLM identifier: NCT01928576. Accessed December 11, 2013
    • Sidney Kimmel Comprehensive Cancer Center. Phase II Anti-PD1 Epigenetic Priming Study in NSCLC. (NA_00084192). Available from: http://clinicaltrials.gov/show/NCT01928576. NLM identifier: NCT01928576. Accessed December 11, 2013.
    • Phase II Anti-PD1 Epigenetic Priming Study in NSCLC.
  • 72
    • 84879759020 scopus 로고    scopus 로고
    • Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
    • Hamid O, Robert C, Daud A, etal. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. 2013;369(2): 134-144.
    • (2013) N Engl J Med. , vol.369 , Issue.2 , pp. 134-144
    • Hamid, O.1    Robert, C.2    Daud, A.3
  • 75
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer JR, Tykodi SS, Chow LQ, etal. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366(26):2455-2465.
    • (2012) N Engl J Med. , vol.366 , Issue.26 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 82
    • 84945459499 scopus 로고    scopus 로고
    • [homepage on the Internet]. US National Institutes of Health. Updated. Available from: Accessed October 8, 2013
    • ClinicalTrials. gov. [homepage on the Internet]. US National Institutes of Health. Updated 2013. Available from: http://clinicaltrials.gov/. Accessed October 8, 2013.
    • (2013) ClinicalTrials. gov.
  • 83
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S, etal. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res. 2009;15(23):7412-7420.
    • (2009) Clin Cancer Res. , vol.15 , Issue.23 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3
  • 84
    • 84859393995 scopus 로고    scopus 로고
    • CTLA-4 blockade with ipilimumab: Long-term follow-up of 177 patients with metastatic melanoma
    • Prieto PA, Yang JC, Sherry RM, etal. CTLA-4 blockade with ipilimumab: long-term follow-up of 177 patients with metastatic melanoma. Clin Cancer Res. 2012;18(7):2039-2047.
    • (2012) Clin Cancer Res. , vol.18 , Issue.7 , pp. 2039-2047
    • Prieto, P.A.1    Yang, J.C.2    Sherry, R.M.3
  • 85
    • 84887262315 scopus 로고    scopus 로고
    • A study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors
    • Herbst RS, Gordon MS, Fine GD, etal. A study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors. J Clin Oncol. 2013;31 Suppl:Abstr 3000.
    • (2013) J Clin Oncol. , vol.31 , Issue.SUPPL. , pp. 3000
    • Herbst, R.S.1    Gordon, M.S.2    Fine, G.D.3
  • 86
    • 84864052441 scopus 로고    scopus 로고
    • Management of immune-related adverse events and kinetics of response with ipilimumab
    • Weber JS, Kähler KC, Hauschild A. Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol. 2012;30(21):2691-2697.
    • (2012) J Clin Oncol. , vol.30 , Issue.21 , pp. 2691-2697
    • Weber, J.S.1    Kähler, K.C.2    Hauschild, A.3
  • 87
    • 34548257760 scopus 로고    scopus 로고
    • Review: Anti-CTLA-4 antibody ipilimumab: Case studies of clinical response and immune-related adverse events
    • Weber J. Review: anti-CTLA-4 antibody ipilimumab: case studies of clinical response and immune-related adverse events. Oncologist. 2007;12(7):864-872.
    • (2007) Oncologist. , vol.12 , Issue.7 , pp. 864-872
    • Weber, J.1


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