Efficacy of clarithromycin and ethambutol for mycobacterium avium complex pulmonary disease: A preliminary study

Annals of the American Thoracic Society

Volumn 11, Issue 1, 2014, Pages 23-29

  Miwa, Seiichi ^a   Shirai, Masahiro ^b   Toyoshima, Mikio ^b   Shirai, Toshihiro ^b   Yasuda, Kazumasa ^b   Yokomura, Koshi ^b   Yamada, Takashi ^b   Masuda, Masafumi ^b   Inui, Naoki ^b   Chida, Kingo ^b   Suda, Takafumi ^b   Hayakawa, Hiroshi ^a,b  

^a National Hospital Organization   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Clarithromycin; Ethambutol; Mycobacterium avium complex; Pulmonary disease; Rifampicin

Indexed keywords

14 HYDROXYCLARITHROMYCIN; CLARITHROMYCIN; ETHAMBUTOL; RIFAMPICIN;

AGED; ANTIBIOTIC THERAPY; ARTICLE; ATYPICAL MYCOBACTERIOSIS; BACTERIUM CULTURE; CONTROLLED STUDY; DIARRHEA; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG ERUPTION; DRUG FEVER; DRUG INDUCED HEADACHE; DRUG WITHDRAWAL; FEMALE; HEPATITIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTENTION TO TREAT ANALYSIS; LOSS OF APPETITE; LUNG INFECTION; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM INTRACELLULARE AVIUM; NAUSEA; OPEN STUDY; OUTCOME ASSESSMENT; PANCYTOPENIA; RANDOMIZED CONTROLLED TRIAL; SPUTUM CULTURE; STOMATITIS; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; VISUAL IMPAIRMENT;

AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTITUBERCULAR; ANTITUBERCULAR AGENTS; CLARITHROMYCIN; DRUG THERAPY, COMBINATION; ETHAMBUTOL; FEMALE; HUMANS; MALE; MIDDLE AGED; MYCOBACTERIUM AVIUM COMPLEX; MYCOBACTERIUM AVIUM-INTRACELLULARE INFECTION; RIFAMPIN; SPUTUM; TREATMENT OUTCOME; TUBERCULOSIS, PULMONARY;

EID: 84893519301     PISSN: 23256621     EISSN: None     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201308-266OC     Document Type: Article

References (19)

1. Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, Holland SM, Horsburgh R, Huitt G, Iademarco MF, et al.; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med 2007;175:367-416. [Published erratum appears in Am J Respir Crit Care Med 175:744-745.] (Pubitemid 46271561)
2. Dautzenberg B, Piperno D, Diot P, Truffot-Pernot C, Chauvin JP; Clarithromycin Study Group of France. Clarithromycin in the treatment of Mycobacterium avium lung infections in patients without AIDS. Chest 1995;107:1035-1040.
3. Wallace RJ Jr, Brown BA, Griffith DE, Girard WM, Murphy DT, Onyi GO, Steingrube VA, Mazurek GH. Initial clarithromycin monotherapy for Mycobacterium avium-intracellulare complex lung disease. Am J Respir Crit Care Med 1994;149:1335-1341. (Pubitemid 24147078)
4. Griffith DE, Brown BA, Girard WM, Murphy DT, Wallace RJ Jr. Azithromycin activity against Mycobacterium avium complex lung disease in patients who were not infected with human immunodeficiency virus. Clin Infect Dis 1996;23:983-989. (Pubitemid 26367481)
5. Wallace RJ Jr, Brown BA, Griffith DE, Girard WM, Murphy DT. Clarithromycin regimens for pulmonary Mycobacterium avium complex. The first 50 patients. Am J Respir Crit Care Med 1996;153:1766-1772. (Pubitemid 26187897)
6. Griffith DE, Brown BA, Girard WM, Griffith BE, Couch LA, Wallace RJ Jr. Azithromycin-containing regimens for treatment of Mycobacterium avium complex lung disease. Clin Infect Dis 2001; 32:1547-1553. (Pubitemid 32458721)
7. Tanaka E, Kimoto T, Tsuyuguchi K, Watanabe I, Matsumoto H, Niimi A, Suzuki K, Murayama T, Amitani R, Kuze F. Effect of clarithromycin regimen for Mycobacterium avium complex pulmonary disease. Am J Respir Crit Care Med 1999;160:866-872. (Pubitemid 29442022)
8. Wallace RJ Jr, Brown BA, Griffith DE, Girard W, Tanaka K. Reduced serum levels of clarithromycin in patients treated with multidrug regimens including rifampin or rifabutin for Mycobacterium avium-M. intracellulare infection. J Infect Dis 1995;171:747-750.
9. van Ingen J, Egelund EF, Levin A, Totten SE, Boeree MJ, Mouton JW, Aarnoutse RE, Heifets LB, Peloquin CA, Daley CL. The pharmacokinetics and pharmacodynamics of pulmonary Mycobacterium avium complex disease treatment. Am J Respir Crit Care Med 2012;186:559-565.
10. Koh WJ, Jeong BH, Jeon K, Lee SY, Shin SJ. Therapeutic drug monitoring in the treatment of Mycobacterium avium complex lung disease. Am J Respir Crit Care Med 2012;186:797-802.
11. Kuroishi S, Nakamura Y, Hayakawa H, Shirai M, Nakano Y, Yasuda K, Suda T, Nakamura H, Chida K. Mycobacterium avium complex disease: prognostic implication of high-resolution computed tomography findings. Eur Respir J 2008;32:147-152.
12. Clinical and Laboratory Standards Institute. Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes: approved standards. Wayne, PA: Clinical and Laboratory Standards Institute. NCCLS document M24-A. 2003.
13. Li W, Rettig J, Jiang X, Francisco DT, Naidong W. Liquid chromatographic-electrospray tandem mass spectrometric determination of clarithromycin in human plasma. Biomed Chromatogr 2006;20:1242-1251. (Pubitemid 44768512)
14. Jiang Y, Wang J, Li H, Wang Y, Gu J. Determination of clarithromycin in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal 2007;43:1460-1464. (Pubitemid 46282397)
15. Griffith DE, Brown-Elliott BA, Langsjoen B, Zhang Y, Pan X, Girard W, Nelson K, Caccitolo J, Alvarez J, Shepherd S, et al. Clinical and molecular analysis of macrolide resistance in Mycobacterium avium complex lung disease. Am J Respir Crit Care Med 2006;174:928-934. (Pubitemid 44564794)
16. Gordin FM, Sullam PM, Shafran SD, Cohn DL, Wynne B, Paxton L, Perry K, Horsburgh CR Jr. A randomized, placebo-controlled study of rifabutin added to a regimen of clarithromycin and ethambutol for treatment of disseminated infection with Mycobacterium avium complex. Clin Infect Dis 1999;28:1080-1085. (Pubitemid 29203542)
17. Hasegawa N, Nishimura T, Ohtani S, Takeshita K, Fukunaga K, Tasaka S, Urano T, Ishii K, Miyairi M, Ishizaka A. Therapeutic effects of various initial combinations of chemotherapy including clarithromycin against Mycobacterium avium complex pulmonary disease. Chest 2009;136:1569-1575.
18. Kobashi Y, Abe M, Mouri K, Obase Y, Kato S, Oka M. Relationship between clinical efficacy for pulmonary MAC and drug-sensitivity test for isolated MAC in a recent 6-year period. J Infect Chemother 2012;18:436-443.
19. Wallace RJ Jr, Brown BA, Griffith DE. Drug intolerance to high-dose clarithromycin among elderly patients. Diagn Microbiol Infect Dis 1993;16:215-221. (Pubitemid 23107304)