DISC1 dynamically regulates synaptic N-Methyl-D-aspartate responses in excitatory neurons

Biological Psychiatry

Volumn 75, Issue 5, 2014, Pages 348-350

  Wang, Guangfu ^a   Zhu, J Julius ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHODIESTERASE IV; SHORT HAIRPIN RNA;

DOWN REGULATION; FRONTAL CORTEX; HIPPOCAMPUS; HUMAN; NERVE CELL PLASTICITY; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PYRAMIDAL NERVE CELL; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; UPREGULATION;

ANIMALS; HUMANS; NERVE TISSUE PROTEINS; NEURONS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84893517455     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.12.003     Document Type: Note

References (10)

1. N.J. Brandon, and A. Sawa Linking neurodevelopmental and synaptic theories of mental illness through DISC1 Nat Rev Neurosci 12 2011 707 722
2. B. Moghaddam, and D. Javitt From revolution to evolution: The glutamate hypothesis of schizophrenia and its implication for treatment Neuropsychopharmacology 37 2012 4 15
3. P.J. Harrison, and D.R. Weinberger Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence Mol Psychiatry 10 2005 40 68
4. C.G. Lau, and R.S. Zukin NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders Nat Rev Neurosci 8 2007 413 426
5. J. Wei, N.M. Graziane, H. Wang, P. Zhong, Q. Wang, and W. Liu et al. Regulation of N-methyl-D-aspartate receptors by disrupted-in-schizophrenia-1 Biol Psychiatry 75 2014 414 424
6. S.G. McCormack, R.L. Stornetta, and J.J. Zhu Synaptic AMPA receptor exchange maintains bidirectional plasticity Neuron 50 2006 75 88
7. R.L. Stornetta, and J.J. Zhu Ras and Rap signaling in synaptic plasticity and mental disorders Neuroscientist 17 2011 54 78
8. A. Hayashi-Takagi, M. Takaki, N. Graziane, S. Seshadri, H. Murdoch, and A.J. Dunlop et al. Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1 Nat Neurosci 13 2010 327 332
9. G.E. Tsai, and P.Y. Lin Strategies to enhance N-methyl-D-aspartate receptor-mediated neurotransmission in schizophrenia, a critical review and meta-analysis Curr Pharm Des 16 2010 522 537
10. P. Paoletti, C. Bellone, and Q. Zhou NMDA receptor subunit diversity: Impact on receptor properties, synaptic plasticity and disease Nat Rev Neurosci 14 2013 383 400