Effectiveness of the Bactiseal Universal Shunt for reducing shunt infection in a Sub-Saharan African context: A retrospective cohort study in 160 Ugandan children: Clinical article

Journal of Neurosurgery: Pediatrics

Volumn 13, Issue 2, 2014, Pages 140-144

  Lane, Jordan D ^a   Mugamba, John ^b   Ssenyonga, Peter ^b   Warf, Benjamin C ^a,b,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CURE Children's Hospital of Uganda   (Uganda)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Bactiseal; Global surgery; Hydrocephalus; Infection; Uganda; Ventriculoperitoneal shunt

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC IMPREGNATED SHUNT CATHETER; ARTICLE; BACTERIUM CULTURE; BRAIN VENTRICLE PERITONEUM SHUNT; CATHETER; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; EQUIPMENT FAILURE; FEMALE; FOLLOW UP; GRAM POSITIVE COCCI; HUMAN; HYDROCEPHALUS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SHUNT INFECTION; UGANDA;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; CEREBROSPINAL FLUID SHUNTS; CHILD; CHILD, PRESCHOOL; CONFOUNDING FACTORS (EPIDEMIOLOGY); COST-BENEFIT ANALYSIS; EQUIPMENT FAILURE; FEMALE; HUMANS; HYDROCEPHALUS; KAPLAN-MEIER ESTIMATE; MALE; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME; UGANDA;

EID: 84893506495     PISSN: 19330707     EISSN: 19330715     Source Type: Journal    
DOI: 10.3171/2013.11.PEDS13394     Document Type: Article

References (14)

1. Gathura E, Poenaru D, Bransford R, Albright AL: Outcomes of ventriculoperitoneal shunt insertion in Sub-Saharan Africa. Clinical article. J Neurosurg Pediatr 6:329-335, 2010
2. Kan P, Kestle J: Lack of efficacy of antibiotic-impregnated shunt systems in preventing shunt infections in children. Childs Nerv Syst 23:773-777, 2007
3. Li L, Padhi A, Ranjeva SL, Donaldson SC, Warf BC, Mugamba J, et al: Association of bacteria with hydrocephalus in Ugandan infants. Clinical article. J Neurosurg Pediatr 7: 73-87, 2011
4. Mwang'ombe NJ, Omulo T: Ventriculoperitoneal shunt surgery and shunt infections in children with non-tumour hydrocephalus at the Kenyatta National Hospital, Nairobi. East Afr Med J 77:386-390, 2000
5. Okoro BA, Ohaegbulam SC: Experience with ventriculo peritoneal shunts at the University of Nigeria Teaching Hospital, Enugu. East Afr Med J 72:322-324, 1995
6. Parker SL, Anderson WN, Lilienfeld S, Megerian JT, McGirt MJ: Cerebrospinal shunt infection in patients receiving anti-biotic-impregnated versus standard shunts. Clinical article. J Neurosurg Pediatr 8:259-265, 2011
7. Richards H, Seeley H, Pickard J: Do antibiotic-impregnated shunt cathters reduce shunt infection? Data from the UK Shunt Registry. Cerebrospinal Fluid Res 3 (Suppl 1):S55, 2006 (Abstract)
8. Schiff SJ, Ranjeva SL, Sauer TD, Warf BC: Rainfall drives hydrocephalus in East Africa. Clinical article. J Neurosurg Pediatr 10:161-167, 2012
9. Warf BC: Comparison of 1-year outcomes for the Chhabra and Codman-Hakim Micro Precision shunt systems in Uganda: a prospective study in 195 children. J Neurosurg (4 Suppl) 102:358-362, 2005
10. Warf BC: Comparison of endoscopic third ventriculostomy alone and combined with choroid plexus cauterization in infants younger than 1 year of age: a prospective study in 550 African children. J Neurosurg (6 Suppl) 103:475-481, 2005
11. Warf BC: Hydrocephalus in Uganda: predominance of infectious origin and primary management with endoscopic third ventriculostomy. J Neurosurg (1 Suppl) 102:1-15, 2005
12. Warf BC: Pediatric hydrocephalus in East Africa: prevalence, causes, treatments, and strategies for the future. World Neurosurg 73:296-300, 2010
13. Warf BC, Alkire BC, Bhai S, Hughes C, Schiff SJ, Vincent JR, et al: Costs and benefits of neurosurgical intervention for infant hydrocephalus in sub-Saharan Africa. Clinical article. J Neurosurg Pediatr 8:509-521, 2011
14. Warf BC, Bhai S, Kulkarni AV, Mugamba J: Shunt survival after failed endoscopic treatment of hydrocephalus. Clinical article. J Neurosurg Pediatr 10:463-470, 2012