Vitamin B12 deficiency: The great masquerader

Pediatric Blood and Cancer

Volumn 61, Issue 4, 2014, Pages 753-755

  Dobrozsi, Sarah ^a   Flood, Veronica H ^a   Panepinto, Julie ^a   Scott, J Paul ^a   Brandow, Amanda ^a  

^a Children's Hospital of Wisconsin   (United States)

Author keywords

Intrinsic factor; Pernicious anemia; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; HEMOGLOBIN; HOMOCYSTEINE; INTRINSIC FACTOR; METHYLMALONIC ACID;

ABDOMINAL PAIN; ADOLESCENT; ANEMIA; ANOREXIA; ARTICLE; CASE REPORT; CHILD; CLINICAL FEATURE; CONSTIPATION; CORPUS CALLOSUM; CYANOCOBALAMIN DEFICIENCY; EOSINOPHILIC GASTROENTERITIS; FAINTNESS; FATIGUE; FEMALE; FOLLOW UP; HEADACHE; HUMAN; IRON DEFICIENCY; MACROCYTIC ANEMIA; MALE; MEGALOCYTOSIS; NEUROIMAGING; NEUROLOGIC DISEASE; PANCYTOPENIA; PARESTHESIA; PERNICIOUS ANEMIA; PLASMAPHERESIS; PRESCHOOL CHILD; PRIORITY JOURNAL; UNSTEADY GAIT; VERTIGO; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; WEIGHT REDUCTION; WHITE MATTER;

INTRINSIC FACTOR; PERNICIOUS ANEMIA; VITAMIN B12;

ADOLESCENT; ADULT; ANEMIA, PERNICIOUS; CHILD, PRESCHOOL; FAILURE TO THRIVE; FEMALE; HUMANS; MALE; PROGNOSIS; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 84893471917     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.24784     Document Type: Article

References (13)

1. Solomon LR. Cobalamin-responsive disorders in the ambulatory care setting: Unreliability of cobalamin, methylmalonic acid, and homocysteine testing. Blood 2005; 105:978-985.
2. Conway SP, Gillies DR, Littlewood JM. Vitamin B12 neuropathy in a 6 year old. Arch Dis Child 1984; 59:575-576.
3. Stabler S, Allen R, Savage D, et al. Clinical spectrum and diagnosis of cobalamin deficiency [see comments]. Blood 1990; 76:871-881.
4. Rasmussen SA, Fernhoff PM, Scanlon KS. Vitamin B12 deficiency in children and adolescents. J Pediatr 2001; 138:10-17.
5. Healton EB, Savage DG, Brust JC, et al. Neurologic aspects of cobalamin deficiency. Medicine 1991; 70:229-245.
6. Fakatselli NM, Delta BG, Hudaverdi EY, et al. Pernicious anemia in childhood. Am J Med Sci 1978; 276:144-152.
7. Hoffman R, Benz E, Jr., Shattil S, et al. Hematology basic principles and practice, 4th edition. Philadelphia, PA: Elsevier; 2005.
8. Pruthi RK, Tefferi A. Pernicious anemia revisited. Mayo Clin Proc 1994; 69:144-150.
9. Aaron S, Kumar S, Vijayan J, et al. Clinical and laboratory features and response to treatment in patients presenting with vitamin B12 deficiency-related neurological syndromes. Neurol india 2005; 53:55-58.
10. Carmel R. Pernicious anemia: The expected findings of very low serum cobalamin levels, anemia, and macrocytosis are often lacking. Arch Intern Med 1988; 148:1712-1714.
11. Reisner EH, Wolff JA, McKay RJ, et al. Juvenile pernicious anemia. Pediatrics 1951; 8:88-106.
12. Savage DG, Lindenbaum J, Stabler SP, et al. Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies. Am J Med 1994; 96:239-246.
13. Watkins D, Rosenblatt DS. Inborn errors of cobalamin absorption and metabolism. Am J Med Genet 2011; 157:33-44.