Genomic test validation for incidental findings

Clinical Chemistry

Volumn 60, Issue 2, 2014, Pages 292-293

  Park, Jason Y ^a   Fortina, Paolo ^b   Kricka, Larry J ^c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL LABORATORY; EXOME; GENE MUTATION; GENETIC ASSOCIATION; GENETIC SCREENING; GENOME; HUMAN; INCIDENTAL FINDING; REVIEW; SEIZURE; DECISION MAKING; DNA SEQUENCE; ETHICS; GENETIC VARIABILITY; GENOMICS; INTERPERSONAL COMMUNICATION; PRACTICE GUIDELINE; REPRODUCIBILITY; STANDARDS; TRENDS;

DECISION MAKING; DISCLOSURE; GENETIC TESTING; GENETIC VARIATION; GENOMICS; GUIDELINES AS TOPIC; HUMANS; INCIDENTAL FINDINGS; REPRODUCIBILITY OF RESULTS; SEQUENCE ANALYSIS, DNA;

EID: 84893470680     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2013.210609     Document Type: Review

References (5)

1. Green RC, Berg JS, Grody WW, Kalia SS, Korf BR, Martin CL, et al. ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. Genet Med 2013;15:565-74.
2. American College of Medical Genetics and Genomics. ACMG clarifies statements on return of incidental findings. http://www.acmg.net/docs/IF- Release.pdf (Accessed May 2013).
3. Allyse M, Michie M. Not-so-incidental findings: the ACMG recommendations on the reporting of incidental findings in clinical whole genome and whole exome sequencing. Trends Biotechnol 2013;31:439-41.
4. McGuire AL, Joffe S, Koenig BA, Biesecker BB, McCullough LB, Blumenthal-Barby JS, et al. Pointcounterpoint. Ethics and genomic incidental findings. Science 2013;340:1047-8.
5. Wolf SM, Annas GJ, Elias S. Point-counterpoint. Patient autonomy and incidental findings in clinical genomics. Science 2013;340:1049-50.