Aphasia predicts unfavorable outcome in mild ischemic stroke patients and prompts thrombolytic treatment

Journal of Stroke and Cerebrovascular Diseases

Volumn 23, Issue 2, 2014, Pages 204-208

  Nesi, Mascia ^a   Lucente, Giuseppe ^b   Nencini, Patrizia ^a   Fancellu, Laura ^c   Inzitari, Domenico ^a  

^a CAREGGI UNIVERSITY HOSPITAL   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF SASSARI   (Italy)

Author keywords

Aphasia; ischemic stroke; mild symptoms; thrombolysis

Indexed keywords

ALTEPLASE;

AGED; APHASIA; ARTICLE; ATAXIA; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CONTROLLED STUDY; DEATH; FEMALE; FIBRINOLYTIC THERAPY; GAZE PARALYSIS; HEMIANOPIA; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; MOTOR DYSFUNCTION; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OUTCOME ASSESSMENT; PREDICTIVE VALUE; PRIORITY JOURNAL; RANKIN SCALE; REGISTER; RETROSPECTIVE STUDY; RISK FACTOR; SENSORY DYSFUNCTION; STROKE UNIT; TRANSIENT ISCHEMIC ATTACK; VISUAL DEPRIVATION; WEAKNESS;

APHASIA; ISCHEMIC STROKE; MILD SYMPTOMS; THROMBOLYSIS;

ADMINISTRATION, INTRAVENOUS; AGED; APHASIA; BRAIN ISCHEMIA; DISABILITY EVALUATION; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; ITALY; MALE; MIDDLE AGED; PATIENT SELECTION; REGISTRIES; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STROKE; TERTIARY CARE CENTERS; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME;

EID: 84893406067     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2012.11.018     Document Type: Article

References (18)

1. P.A. Barber, J. Zangh, and A.M. Demchuk et al. Why are stroke patients excluded from TPA therapy? Neurology 56 2001 1015 1020
2. D. Kleidorfer, B. Kissela, and A. Schneider et al. Eligibility for recombinant tissue plasminogen activator in acute ischemic stroke: a population-based study Stroke 35 2004 e27 e29
3. D. Cocho, R. Belvís, and J. Martí-Fabregas et al. Reason for exclusion from thrombolytic therapy following acute ischemic stroke Neurology 64 2005 719 720
4. E.E. Smith, A.R. Abdullah, and I. Petkovska et al. Poor outcome in patients who do not receive intravenous tissue plasminogen activator because of mild improving ischemic stroke Cerebrovasc Dis 36 2005 2497 2499
5. K. Nedeltchev, B. Schwegler, and T. Haefeli et al. Outcome of stroke with mild or rapidly improving symptoms Stroke 38 2007 2531 2535
6. E.E. Smith, G.C. Fonarow, and M. Reeves et al. Outcome in mild or rapidly improving stroke not treated with intravenous recombinant tissue-type plasminogen activator: findings from get to the guidelines-stroke Stroke 42 2011 3110 3115
7. D. Cocho, R. Belvis, and J. Marti-Fabregas et al. Does thrombolysis benefit patients with lacunar syndrome? Eur Neurol 55 2006 70 73
8. N. Wahlgren, N. Ahmed, and A. Davalos et al. Thrombolysis with alteplase for acute ischemic stroke in the safe implementation of thrombolysis in stroke-monitoring study (SITS-MOST): an observational study Lancet 369 2007 275 282
9. The National Institute of Neurological Disorders and Stroke rtPA Stroke Study Group Tissue plasminogen activator for acute ischemic stroke N Engl J Med 333 1995 1581 1587
10. H.P. Adams Jr., G. del Zoppo, and M.J. Alberts et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups; the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists Circulation 115 2007 478 534
11. Linee guida italiane di prevenzione e trattamento dell'Ictus Cerebrale. Stroke Prevention And Educational Awarness Diffusion (SPREAD). Casa editrice CATEL (Milano). III Edizione 2003.
12. T. Brott, H.P. Adams Jr., and C.P. Olinger et al. Measurements of acute cerebral infarction: a clinical examination scale Stroke 20 1989 864 870
13. R. Bonita, and R. Beaglehole Modification of Rankin scale: recovery of motor function after stroke Stroke 19 1988 1497 1500
14. H.P. Adams Jr., B.H. Bendixen, and L.J. Kappelle et al. Classification of subtype of acute ischemic stroke: definitions for use in a multicenter clinical trial; TOAST, Trial of Org 10172 in Acute Stroke Treatment Stroke 24 1993 35 41
15. U. Fischer, A. Baumgertner, and M. Arnold et al. What is a minor stroke? Stroke 41 2010 661 666
16. M. Köhrmann, T. Nowe, and H.B. Huttner et al. Safety and outcome after thrombolysis in stroke patients with mild symptoms Cerebrovasc Dis 27 2009 160 166
17. E.C. Leira, B.R. Ludwig, and M.E. Gurol et al. The types of neurological deficits might not justify withholding treatment in patients with low total National Institutes of Health Stroke Scale score Stroke 43 2012 1524
18. The Publications Committee for the Trial of Org 10172 in Acute Stroke Treatment (TOAST) Investigators. Low molecular weight heparinoid, ORG 10172 (danaparoid), and outcome after stroke: a randomized controlled study JAMA 279 1998 1265 1272