Hypoxia alters phosphorylation status of insulin-like growth factor (IGF)-binding protein-1 and attenuates biological activities of IGF-I in HepG2 cell cultures

Journal of Obstetrics and Gynaecology Research

Volumn 39, Issue 9, 2013, Pages 1367-1373

  Tsunawaki, Tomonori ^a   Sakai, Keiji ^a   Momomura, Mai ^a   Wachi, Yuichi ^a   Matsuzawa, Yukiko ^a   Iwashita, Mitsutoshi ^a  

^a KYORIN UNIVERSITY   (Japan)

Author keywords

fetal growth; hypoxia; insulin like growth factor binding protein 1

Indexed keywords

DODECYL SULFATE SODIUM; OXYGEN; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; IGF1 PROTEIN, HUMAN; IGFBP1 PROTEIN, HUMAN; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN;

ARTICLE; CELL CULTURE; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOBLOTTING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; CELL HYPOXIA; CELL STRAIN HEPG2; DRUG ANTAGONISM; FETUS GROWTH; INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-1; LIVER CELL; METABOLISM; PHOSPHORYLATION; PROTEIN PROCESSING; SECRETION (PROCESS); SIGNAL TRANSDUCTION; UPREGULATION; ANTAGONISTS AND INHIBITORS; HEPG2 CELL LINE;

FETAL GROWTH; HYPOXIA; INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-1;

CELL HYPOXIA; HEP G2 CELLS; HEPATOCYTES; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR I; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84893385401     PISSN: 13418076     EISSN: 14470756     Source Type: Journal    
DOI: 10.1111/jog.12078     Document Type: Article

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