Inhibition of Notch signaling leads to increased intracellular ROS by up-regulating Nox4 expression in primary HUVECs

Cellular Immunology

Volumn 287, Issue 2, 2014, Pages 129-135

  Cai, Wei Xia ^a   Liang, Liang ^b   Wang, Li ^b   Han, Jun Tao ^a   Zhu, Xiong Xiang ^a   Han, Hua ^b   Hu, Da Hai ^a   Zhang, Ping ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

HUVECs; Notch signaling; Nox4; ROS; VEGFR2

Indexed keywords

GAMMA SECRETASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; NOTCH RECEPTOR; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4;

ANGIOGENESIS; ARTICLE; CELL ADHESION; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SPACE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPERFUSION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WESTERN BLOTTING;

HUVECS; NOTCH SIGNALING; NOX4; ROS; VEGFR2;

AMYLOID PRECURSOR PROTEIN SECRETASES; CELL ADHESION; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NADPH OXIDASE; NEOVASCULARIZATION, PHYSIOLOGIC; OLIGOPEPTIDES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84893365489     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2013.12.009     Document Type: Article

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