Initial experience with upfront arterial and perfusion imaging among ischemic stroke patients presenting within the 4.5-hour time window

Journal of Stroke and Cerebrovascular Diseases

Volumn 23, Issue 2, 2014, Pages 220-224

  Noorian, Ali Reza ^a   Bryant, Katja ^a   Aiken, Ashley ^a   Nicholson, Andrew D ^a   Edwards, Adam B ^a   Markowski, Mason P ^a   Dehkharghani, Seena ^a   Bouloute, Jemisha C ^a   Abney, Jacquelyn ^a   Nahab, Fadi ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute stroke; computed tomographic perfusion; revascularization; tissue plasminogen activator

Indexed keywords

ALTEPLASE;

ADULT; AGED; ARTICLE; BRAIN ISCHEMIA; BRAIN PERFUSION; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; EMERGENCY HEALTH SERVICE; FEMALE; FIBRINOLYTIC THERAPY; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MEDICAL DECISION MAKING; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NEUROIMAGING; PRIORITY JOURNAL;

ACUTE STROKE; COMPUTED TOMOGRAPHIC PERFUSION; REVASCULARIZATION; TISSUE PLASMINOGEN ACTIVATOR;

AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; CEREBRAL ANGIOGRAPHY; CEREBRAL REVASCULARIZATION; CEREBROVASCULAR CIRCULATION; CLINICAL COMPETENCE; CORONARY VESSELS; DECISION SUPPORT TECHNIQUES; FEMALE; GEORGIA; HOSPITALS, UNIVERSITY; HUMANS; LEARNING CURVE; MALE; MIDDLE AGED; PATIENT SELECTION; PERFUSION IMAGING; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; STROKE; TIME FACTORS; TIME-TO-TREATMENT; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 84893355790     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2012.12.008     Document Type: Article

References (21)

1. D. Lloyd-Jones, R.J. Adams, and T.M. Brown et al. Heart disease and stroke statistics - 2010 update: A report from the American Heart Association Circulation 121 2010 e46 e215
2. Centers for Disease Control and Prevention Prevalence of disabilities and associated health conditions among adults: United States, 1999 MMWR Morb Mortal Wkly Rep 50 2001 120 125
3. R.G. Nogueira, L.H. Schwamm, and J.A. Hirsch Endovascular approaches to acute stroke, part 1: Drugs, devices and data Am J Neuroradiol 30 2009 649 661
4. National Institute of Neurological Disorders and Stroke Study Group Tissue plasminogen activator for acute ischemic stroke N Engl J Med 333 1995 1581 1587
5. W. Hacke, M. Kaste, and E. Bluhmki et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke N Engl J Med 359 2008 1317 1329
6. D. Leys, J.P. Pruvo, and O. Godefroy et al. Prevalence and significance of hyperdense middle cerebral artery in acute stroke Stroke 23 1992 317 324
7. M.B. Maas, K.L. Furie, and M.H. Lev et al. National Institutes of Health Stroke Scale Score is poorly predictive of proximal occlusion in acute cerebral ischemia Stroke 40 2009 2988 2993
8. M. Wintermark, A.E. Flanders, and B. Velthuis et al. Perfusion-CT assessment of infarct core and penumbra: Receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke Stroke 37 2006 979 985
9. B.J. Barrett, and P.S. Parfrey Clinical practice. Preventing nephropathy induced by contrast medium N Engl J Med 354 2006 379 386
10. P.D. Schellinger, R.N. Bryan, and L.R. Caplan et al. Evidence-based guideline: The role of diffusion and perfusion MRI for the diagnosis of acute ischemic stroke: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology Neurology 75 2010 177
11. C.H. Riedel, P. Zimmermann, and U. Jensen-Kondering et al. The importance of size: Successful recanalization by intravenous thrombolysis in acute anterior stroke depends on thrombus length Stroke 42 2011 1775 1777
12. P.A. Barber, J. Zhang, and A.M. Demchuk et al. Why are stroke patients excluded from tPA therapy? An analysis of patient eligibility Neurology 56 2001 1015 1020
13. J. Grotta NIHSS/EIC mismatch explains the >1/3 MCA conundrum Stroke 34 2003 e148 e149
14. J.M. Wardlaw, A.J. Farrall, and D. Perry et al. Factors influencing the detection of early CT signs of cerebral ischemia: An internet-based, international multiobserver study Stroke 38 2007 1250 1256
15. S. Agarwal, P.S. Jones, and J.A. Alawneh et al. Does perfusion computed tomography facilitate clinical decision making for thrombolysis in unselected acute patients with suspected ischaemic stroke? Cerebrovasc Dis 32 2011 227 233
16. R. Gupta, A. Horev, and D. Wisco et al. CT perfusion increases time to reperfusion and may not enhance patient selection for endovascular reperfusion therapies in acute ischemic stroke Stroke 43 2012 A207
17. A. Meretoja, D. Strbian, and S. Mustanoja et al. Reducing in-hospital delay to 20 minutes in stroke thrombolysis Neurology 79 2012 306 313
18. M. Wintermark, and M.H. Lev FDA investigates the safety of brain perfusion CT Am J Neuroradiol 31 2010 2 3
19. A.A. Konstas, G.V. Goldmakher, and T.Y. Lee et al. Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke, part 1: Theoretic basis AJNR Am J Neuroradiol 30 2009 662 668
20. A.A. Konstas, G.V. Goldmakher, and T.Y. Lee et al. Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke, part 2: Technical implementations AJNR Am J Neuroradiol 30 2009 885 892
21. A. Mnyusiwalla, R.I. Aviv, and S.P. Symons et al. Radiation dose from multidetector row CT imaging for acute stroke Neuroradiology 51 2009 635 640