메뉴 건너뛰기




Volumn 60, Issue 4, 2013, Pages 641-646

CTLA-4 polymorphisms (+49 A/G and -318 C/T) are important genetic determinants of AITD susceptibility and predisposition to high levels of thyroid autoantibodies in Polish children - Preliminary study

Author keywords

Autoimmune thyroid disease; CTLA 4; Graves' disease; Hashimoto's thyroiditis; Single nucleotide polymorphism; TAb production

Indexed keywords

AUTOANTIBODY; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4;

EID: 84893355545     PISSN: 0001527X     EISSN: 1734154X     Source Type: Journal    
DOI: 10.18388/abp.2013_2034     Document Type: Article
Times cited : (17)

References (30)
  • 1
    • 2242465734 scopus 로고    scopus 로고
    • A common autoimmunity predisposing signal peptide variant of the cytotoxic T-lymphocyte antigen 4 results in inefficient glycosylation of the susceptibility allele
    • Anjos S, Nguyen A, Ounissi-Benkalha H, Tessier MC, Polychronakos C (2002) A common autoimmunity predisposing signal peptide variant of the cytotoxic T-lymphocyte antigen 4 results in inefficient glycosylation of the susceptibility allele. J Biol Chem 277: 46478-46486.
    • (2002) J Biol Chem , vol.277 , pp. 46478-46486
    • Anjos, S.1    Nguyen, A.2    Ounissi-Benkalha, H.3    Tessier, M.C.4    Polychronakos, C.5
  • 2
    • 10344224011 scopus 로고    scopus 로고
    • Association of the cytotoxic T lymphocyte-associated antigen 4 gene with type 1 diabetes: evidence for independent effects of two polymorphisms on the same haplotype block
    • Anjos SM, Tessier MC, Polychronakos C (2004) Association of the cytotoxic T lymphocyte-associated antigen 4 gene with type 1 diabetes: evidence for independent effects of two polymorphisms on the same haplotype block. J Clin Endocrinol Metab 89: 6257-6265.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 6257-6265
    • Anjos, S.M.1    Tessier, M.C.2    Polychronakos, C.3
  • 4
    • 70349335691 scopus 로고    scopus 로고
    • 49A/G and CT60 polymorphisms of the cytotoxic Tlymphocyte-associated antigen 4 gene associated with autoimmune thyroid disease
    • Bicek A, Zaletel K, Gaberscek S, Pirnat E, Krhin B, Stopar TG, Hojker S (2009) 49A/G and CT60 polymorphisms of the cytotoxic Tlymphocyte-associated antigen 4 gene associated with autoimmune thyroid disease. Hum Immunol 70: 820-824.
    • (2009) Hum Immunol , vol.70 , pp. 820-824
    • Bicek, A.1    Zaletel, K.2    Gaberscek, S.3    Pirnat, E.4    Krhin, B.5    Stopar, T.G.6    Hojker, S.7
  • 6
    • 32144456238 scopus 로고    scopus 로고
    • Genetic analysis and functional evaluation of the C/T (-318) and A/G(-1661) polymorphisms of the CTLA-4 gene in patients affected with Graves' disease
    • Chistiakov DA, Savost'anov KV, Turakulov RI, Efremov IA, Demurov LM (2006) Genetic analysis and functional evaluation of the C/T (-318) and A/G(-1661) polymorphisms of the CTLA-4 gene in patients affected with Graves' disease. Clin Immunol 118: 233-242.
    • (2006) Clin Immunol , vol.118 , pp. 233-242
    • Chistiakov, D.A.1    Savost'anov, K.V.2    Turakulov, R.I.3    Efremov, I.A.4    Demurov, L.M.5
  • 8
    • 34547803346 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis
    • Kavvoura FK, Akamizu T, Awata T, Ban Y, Chistiakov DA, Frydecka I et al. (2007) Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis. J Clin Endocrinol Metab 92: 3162-3170.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3162-3170
    • Kavvoura, F.K.1    Akamizu, T.2    Awata, T.3    Ban, Y.4    Chistiakov, D.A.5    Frydecka, I.6
  • 9
    • 0034548720 scopus 로고    scopus 로고
    • CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease
    • Kouki T, Sawai Y, Gardine CA, Fisfalen ME, Alegre ML, DeGroot LJ (2000) CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease. J Imunol 165: 6606-6611.
    • (2000) J Imunol , vol.165 , pp. 6606-6611
    • Kouki, T.1    Sawai, Y.2    Gardine, C.A.3    Fisfalen, M.E.4    Alegre, M.L.5    DeGroot, L.J.6
  • 10
    • 0036215404 scopus 로고    scopus 로고
    • Relation of three polymorphisms of the CTLA-4 gene in patients with Graves' disease
    • Kouki T, Gardine CA, Yanagawa T, Degroot LJ (2002) Relation of three polymorphisms of the CTLA-4 gene in patients with Graves' disease. J Endocrinol Invest 25: 208-213.
    • (2002) J Endocrinol Invest , vol.25 , pp. 208-213
    • Kouki, T.1    Gardine, C.A.2    Yanagawa, T.3    Degroot, L.J.4
  • 11
    • 0034139830 scopus 로고    scopus 로고
    • CTLA4 in autoimmune diseases-a general susceptibility gene to autoimmunity?
    • Kristiansen OP, Larsen ZM, Pociot F (2000) CTLA4 in autoimmune diseases-a general susceptibility gene to autoimmunity? Genes Immun 1: 170-184.
    • (2000) Genes Immun , vol.1 , pp. 170-184
    • Kristiansen, O.P.1    Larsen, Z.M.2    Pociot, F.3
  • 12
    • 77956697931 scopus 로고    scopus 로고
    • Expression of CD152 (CTLA-4) in children with autoimmune thyroid itis and +49 A/G polymorphism of exon 1 of the CTLA-4 gene
    • Kucharska AM, Gorska E, Wasik M, Pyrzak B, Demkow U (2009) Expression of CD152 (CTLA-4) in children with autoimmune thyroid itis and +49 A/G polymorphism of exon 1 of the CTLA-4 gene. J Physiol Pharmacol 60: 77-80.
    • (2009) J Physiol Pharmacol , vol.60 , pp. 77-80
    • Kucharska, A.M.1    Gorska, E.2    Wasik, M.3    Pyrzak, B.4    Demkow, U.5
  • 13
    • 0035346140 scopus 로고    scopus 로고
    • CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms
    • Ligers A, Teleshova N, Masterman T, Huang WX, Hillert J (2001) CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms. Genes Immun 2: 145-152.
    • (2001) Genes Immun , vol.2 , pp. 145-152
    • Ligers, A.1    Teleshova, N.2    Masterman, T.3    Huang, W.X.4    Hillert, J.5
  • 14
    • 0036773319 scopus 로고    scopus 로고
    • Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells
    • Manzotti CN, Tipping H, Perry LC, Mead KI, Blair PJ, Zheng Y, Sansom DM (2002) Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells. Eur J Immunol 32: 2888-2896.
    • (2002) Eur J Immunol , vol.32 , pp. 2888-2896
    • Manzotti, C.N.1    Tipping, H.2    Perry, L.C.3    Mead, K.I.4    Blair, P.J.5    Zheng, Y.6    Sansom, D.M.7
  • 16
    • 0010690218 scopus 로고    scopus 로고
    • Polymorphism in the promoter and exon 1 of the cytotoxic T lymphocyte antigen-4 gene associated with autoimmune thyroid disease in Koreans
    • Park YJ, Chung HK, Park DJ, Kim WB, Kim SW, Koh JJ, Cho BY (2000) Polymorphism in the promoter and exon 1 of the cytotoxic T lymphocyte antigen-4 gene associated with autoimmune thyroid disease in Koreans. Thyroid 10: 453-459.
    • (2000) Thyroid , vol.10 , pp. 453-459
    • Park, Y.J.1    Chung, H.K.2    Park, D.J.3    Kim, W.B.4    Kim, S.W.5    Koh, J.J.6    Cho, B.Y.7
  • 17
    • 84863965327 scopus 로고    scopus 로고
    • CTLA-4 gene polymorphisms and their influence on the predisposition to the autoimmune thyroid diseases (Graves' disease and Hashimoto's thyroiditis)
    • Pastuszak-Lewandoska D, Sewerynek E, Domanska D, Gladys A, Skrzypczak R, Brzezianska E (2012) CTLA-4 gene polymorphisms and their influence on the predisposition to the autoimmune thyroid diseases (Graves' disease and Hashimoto's thyroiditis). Arch Med Sci 8: 415-421.
    • (2012) Arch Med Sci , vol.8 , pp. 415-421
    • Pastuszak-Lewandoska, D.1    Sewerynek, E.2    Domanska, D.3    Gladys, A.4    Skrzypczak, R.5    Brzezianska, E.6
  • 18
    • 0034745481 scopus 로고    scopus 로고
    • Association of DRB1*04-DQB1*0301 haplotype and lack of association of two polymorphic sites at CTLA-4 gene with Hashimoto's thyroiditis in an Italian population
    • Petrone A, Giorgi G, Mesturino CA, Capizzi M, Cascino I, Nistico L, Osborn J, Di Mario U, Buzzetti R (2001) Association of DRB1*04-DQB1*0301 haplotype and lack of association of two polymorphic sites at CTLA-4 gene with Hashimoto's thyroiditis in an Italian population. Thyroid 11: 171-175.
    • (2001) Thyroid , vol.11 , pp. 171-175
    • Petrone, A.1    Giorgi, G.2    Mesturino, C.A.3    Capizzi, M.4    Cascino, I.5    Nistico, L.6    Osborn, J.7    Di Mario, U.8    Buzzetti, R.9
  • 19
    • 20144363340 scopus 로고    scopus 로고
    • CT60 single nucleotide polymorphisms of the cytotoxic T-lymphocyte associated antigen-4 gene region is associated with Graves' disease in an Italian population
    • Petrone A, Giorgi G, Galgani A, Alemanno I, Corsello SM, Signore A, Di Mario U, Nisticò L, Cascino I, Buzzetti R (2005) CT60 single nucleotide polymorphisms of the cytotoxic T-lymphocyte associated antigen-4 gene region is associated with Graves' disease in an Italian population. Thyroid 15: 232-238.
    • (2005) Thyroid , vol.15 , pp. 232-238
    • Petrone, A.1    Giorgi, G.2    Galgani, A.3    Alemanno, I.4    Corsello, S.M.5    Signore, A.6    Di Mario, U.7    Nisticò, L.8    Cascino, I.9    Buzzetti, R.10
  • 21
    • 0037648405 scopus 로고    scopus 로고
    • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
    • Ueda H, Howson JM, Esposito L, Heward J, Snook H, Chamberlain G, et al. (2003) Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423: 506-511.
    • (2003) Nature , vol.423 , pp. 506-511
    • Ueda, H.1    Howson, J.M.2    Esposito, L.3    Heward, J.4    Snook, H.5    Chamberlain, G.6
  • 22
    • 0038807883 scopus 로고    scopus 로고
    • CTLA4 gene and Graves' disease: association of Graves' disease with the CTLA4 exon 1 and intron 1 polymorphisms, but not with the promoter polymorphism
    • Vaidya B, Oakes EJ, Imrie H, Dickinson AJ, Perros P, Kendall-Taylor P, Pearce SH (2003) CTLA4 gene and Graves' disease: association of Graves' disease with the CTLA4 exon 1 and intron 1 polymorphisms, but not with the promoter polymorphism. Clin Endocrinol (Oxf) 58: 732-735.
    • (2003) Clin Endocrinol (Oxf) , vol.58 , pp. 732-735
    • Vaidya, B.1    Oakes, E.J.2    Imrie, H.3    Dickinson, A.J.4    Perros, P.5    Kendall-Taylor, P.6    Pearce, S.H.7
  • 23
    • 44449155771 scopus 로고    scopus 로고
    • A multilocus model of the genetic architecture of autoimmune thyroid disorder, with clinical implications
    • Vieland VJ, Huang Y, Bartlett C, Davies TF, Tomer Y (2008) A multilocus model of the genetic architecture of autoimmune thyroid disorder, with clinical implications. Am J Hum Genet 82: 1349-1356.
    • (2008) Am J Hum Genet , vol.82 , pp. 1349-1356
    • Vieland, V.J.1    Huang, Y.2    Bartlett, C.3    Davies, T.F.4    Tomer, Y.5
  • 24
    • 0036615259 scopus 로고    scopus 로고
    • A CTLA-4 gene polymorphism at position-318 in the promoter region affects the expression of protein
    • Wang XB, Zhao X, Giscombe R, Lefvert AK (2002) A CTLA-4 gene polymorphism at position-318 in the promoter region affects the expression of protein. Genes Immun 3: 233-234.
    • (2002) Genes Immun , vol.3 , pp. 233-234
    • Wang, X.B.1    Zhao, X.2    Giscombe, R.3    Lefvert, A.K.4
  • 25
    • 84862701409 scopus 로고    scopus 로고
    • CD40 C/T(-1) and CTLA-4 A/G(49) SNPs are associated with autoimmune thyroid diseases in the Chinese population
    • Yang J, Qin Q, Yan N, Zhu YF, Li C, Yang XJ, Wang X, Pandey M, Hou P, Zhang JA (2012) CD40 C/T(-1) and CTLA-4 A/G(49) SNPs are associated with autoimmune thyroid diseases in the Chinese population. Endocrine 41: 111-115.
    • (2012) Endocrine , vol.41 , pp. 111-115
    • Yang, J.1    Qin, Q.2    Yan, N.3    Zhu, Y.F.4    Li, C.5    Yang, X.J.6    Wang, X.7    Pandey, M.8    Hou, P.9    Zhang, J.A.10
  • 27
    • 0036268414 scopus 로고    scopus 로고
    • CTLA-4 gene A-G polymorphism and childhood Graves' disease
    • Yung E, Cheng PS, Fok TF, Wong GW (2002) CTLA-4 gene A-G polymorphism and childhood Graves' disease. Clin Endocrinol (Oxf) 56: 649-653.
    • (2002) Clin Endocrinol (Oxf) , vol.56 , pp. 649-653
    • Yung, E.1    Cheng, P.S.2    Fok, T.F.3    Wong, G.W.4
  • 28
    • 0035986941 scopus 로고    scopus 로고
    • The influence of the exon 1 polymorphism of the cytotoxic T lymphocyte antigen 4 gene on thyroid antibody production in patients with newly diagnosed Graves' disease
    • Zaletel K, Krhin B, Gaberscek S, Pirnat E, Hojker S (2002) The influence of the exon 1 polymorphism of the cytotoxic T lymphocyte antigen 4 gene on thyroid antibody production in patients with newly diagnosed Graves' disease. Thyroid 12: 373-376.
    • (2002) Thyroid , vol.12 , pp. 373-376
    • Zaletel, K.1    Krhin, B.2    Gaberscek, S.3    Pirnat, E.4    Hojker, S.5
  • 29
    • 33645114938 scopus 로고    scopus 로고
    • Thyroid autoantibody production is influenced by exon 1 and promoter CTLA-4 polymorphisms in patients with Hashimoto's thyroiditis
    • Zaletel K, Krhin B, Gaberscek S, Hojker S (2006) Thyroid autoantibody production is influenced by exon 1 and promoter CTLA-4 polymorphisms in patients with Hashimoto's thyroiditis. Int J Immunogenet 33: 87-91.
    • (2006) Int J Immunogenet , vol.33 , pp. 87-91
    • Zaletel, K.1    Krhin, B.2    Gaberscek, S.3    Hojker, S.4
  • 30
    • 34247586828 scopus 로고    scopus 로고
    • Association of Graves' disease and Graves' ophthalmopathy with the polymorphisms in promoter and exon 1 of cytotoxic T lymphocyte associated antigen-4 gene
    • Zhang Q, Yang YM, Lv XY (2006) Association of Graves' disease and Graves' ophthalmopathy with the polymorphisms in promoter and exon 1 of cytotoxic T lymphocyte associated antigen-4 gene. J Zhejiang Univ Sci B 7: 887-891.
    • (2006) J Zhejiang Univ Sci B , vol.7 , pp. 887-891
    • Zhang, Q.1    Yang, Y.M.2    Lv, X.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.