메뉴 건너뛰기




Volumn 14, Issue 2, 2014, Pages 151-161

Review of management issues in relapsed osteosarcoma

Author keywords

osteosarcoma; relapse; treatment

Indexed keywords

ADOLESCENT; BONE NEOPLASMS; CHILD; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; HUMANS; NEOPLASM RECURRENCE, LOCAL; OSTEOSARCOMA; PROGNOSIS; SURVIVAL RATE;

EID: 84893300625     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/14737140.2014.863453     Document Type: Review
Times cited : (30)

References (102)
  • 1
    • 0344171979 scopus 로고    scopus 로고
    • Common musculoskeletal tumors of childhood and adolescence
    • Arndt CAS, Crist WM. Common musculoskeletal tumors of childhood and adolescence. N. Engl. J. Med. 341(5), 342-352 (1999).
    • (1999) N. Engl. J. Med. , vol.341 , Issue.5 , pp. 342-352
    • Arndt, C.A.S.1    Crist, W.M.2
  • 2
    • 0022656434 scopus 로고
    • The effect of adjuvant chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity
    • Link MP, Goorin AM, Miser AW, et al. The effect of adjuvant chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity. N. Engl. J. Med. 314(25), 1600-1606 (1986).
    • (1986) N. Engl. J. Med. , vol.314 , Issue.25 , pp. 1600-1606
    • Link, M.P.1    Goorin, A.M.2    Miser, A.W.3
  • 4
    • 0034841885 scopus 로고    scopus 로고
    • Presurgical window of carboplatin and surgery and multidrug chemotherapy for the treatment of newly diagnosed metastatic or unresectable osteosarcoma: Pediatric Oncology Group Trial
    • Ferguson WS, Harris MB, Goorin AM, et al. Presurgical window of carboplatin and surgery and multidrug chemotherapy for the treatment of newly diagnosed metastatic or unresectable osteosarcoma: Pediatric Oncology Group Trial. J. Pediatr. Hematol. Oncol. 23(6), 340-348 (2001).
    • (2001) J. Pediatr. Hematol. Oncol. , vol.23 , Issue.6 , pp. 340-348
    • Ferguson, W.S.1    Harris, M.B.2    Goorin, A.M.3
  • 5
    • 0037080289 scopus 로고    scopus 로고
    • Phase II/III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma: A pediatric oncology group trial
    • Goorin AM, Harris MB, Bernstein M, et al. Phase II/III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma: a pediatric oncology group trial. J. Clin. Oncol. 20(2), 426-433 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.2 , pp. 426-433
    • Goorin, A.M.1    Harris, M.B.2    Bernstein, M.3
  • 7
    • 0020510719 scopus 로고
    • Survival following aggressive resection of pulmonary metastases from osteogenic sarcoma: Analysis of prognostic factors
    • Putnam JB Jr, Roth JA, Wesley MN, Johnston MR, Rosenberg SA. Survival following aggressive resection of pulmonary metastases from osteogenic sarcoma: analysis of prognostic factors. Ann. Thorac. Surg. 36(5), 516-23 (1983).
    • (1983) Ann. Thorac. Surg. , vol.36 , Issue.5 , pp. 516-523
    • Putnam Jr., J.B.1    Roth, J.A.2    Wesley, M.N.3    Johnston, M.R.4    Rosenberg, S.A.5
  • 8
    • 77955122716 scopus 로고    scopus 로고
    • Inhaled gm-csf for first pulmonary recurrence of osteosarcoma; Effects on disease free survival animmunomodulation: A report from the childrens oncology group
    • Arndt CAS, Koshkina NV, Inwards CY, et al. inhaled gm-csf for first pulmonary recurrence of osteosarcoma; effects on disease free survival animmunomodulation: a report from the childrens oncology group. Clin. Cancer Res. 16(15), 4024-4030 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , Issue.15 , pp. 4024-4030
    • Arndt, C.A.S.1    Koshkina, N.V.2    Inwards, C.Y.3
  • 9
    • 84856343533 scopus 로고    scopus 로고
    • A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: An Italian Sarcoma Group study
    • Grignani G, Palmerini E, Dileo P, et al. A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study. Ann. Oncol. 23(2), 508-516 (2012).
    • (2012) Ann. Oncol. , vol.23 , Issue.2 , pp. 508-516
    • Grignani, G.1    Palmerini, E.2    Dileo, P.3
  • 10
    • 18044379986 scopus 로고    scopus 로고
    • P53 gene therapy of human osteosarcoma using a transferrin-modified cationic liposome
    • Nakase M, Inui M, Okumura K, Kamei T, Nakamura S, Tagawa T. p53 gene therapy of human osteosarcoma using a transferrin-modified cationic liposome. Mol. Cancer Ther. 4(4), 625-631 (2005).
    • (2005) Mol. Cancer Ther. , vol.4 , Issue.4 , pp. 625-631
    • Nakase, M.1    Inui, M.2    Okumura, K.3    Kamei, T.4    Nakamura, S.5    Tagawa, T.6
  • 11
    • 0028965019 scopus 로고
    • Systemic relapse of patients with osteogenic sarcoma. Prognostic factors for long term survival
    • Saeter G, Høie J, Stenwig AE, Johansson AK, Hannisdal E, Solheim OP. Systemic relapse of patients with osteogenic sarcoma. Prognostic factors for long term survival. Cancer 75(5), 1084-1093 (1995).
    • (1995) Cancer , vol.75 , Issue.5 , pp. 1084-1093
    • Saeter, G.1    Høie, J.2    Stenwig, A.E.3    Johansson, A.K.4    Hannisdal, E.5    Solheim, O.P.6
  • 12
    • 0021676828 scopus 로고
    • Changing metastatic patterns of osteosarcoma
    • Giuliano AE, Feig S, Eilber FR. Changing metastatic patterns of osteosarcoma. Cancer 54(10), 2160-2164 (1984).
    • (1984) Cancer , vol.54 , Issue.10 , pp. 2160-2164
    • Giuliano, A.E.1    Feig, S.2    Eilber, F.R.3
  • 13
    • 0021048353 scopus 로고
    • Osteogenic sarcoma: Alterations in the pattern of pulmonary metastases with adjuvant chemotherapy
    • Jaffe N, Smith E, Abelson HT, Frei E. Osteogenic sarcoma: alterations in the pattern of pulmonary metastases with adjuvant chemotherapy. J. Clin. Oncol. 1(4), 251-254 (1983).
    • (1983) J. Clin. Oncol. , vol.1 , Issue.4 , pp. 251-254
    • Jaffe, N.1    Smith, E.2    Abelson, H.T.3    Frei, E.4
  • 14
    • 0026032155 scopus 로고
    • Changing pattern of pulmonary metastases with adjuvant chemotherapy in patients with osteosarcoma: Results from the multiinstitutional osteosarcoma study
    • Goorin AM, Shuster JJ, Baker A, Horowitz ME, Meyer WH, Link MP. Changing pattern of pulmonary metastases with adjuvant chemotherapy in patients with osteosarcoma: results from the multiinstitutional osteosarcoma study. J. Clin. Oncol. 9(4), 600-605 (1991).
    • (1991) J. Clin. Oncol. , vol.9 , Issue.4 , pp. 600-605
    • Goorin, A.M.1    Shuster, J.J.2    Baker, A.3    Horowitz, M.E.4    Meyer, W.H.5    Link, M.P.6
  • 15
    • 7344229308 scopus 로고    scopus 로고
    • Long-term results of the co-operative German-Austrian-Swiss osteosarcoma study groups protocol COSS-86 of intensive multidrug chemotherapy and surgery for osteosarcoma of the limbs
    • Fuchs N, Bielack SS, Epler D, et al. Long-term results of the co-operative German-Austrian-Swiss osteosarcoma study groups protocol COSS-86 of intensive multidrug chemotherapy and surgery for osteosarcoma of the limbs. Ann. Oncol. 9(8), 893-899 (1998).
    • (1998) Ann. Oncol. , vol.9 , Issue.8 , pp. 893-899
    • Fuchs, N.1    Bielack, S.S.2    Epler, D.3
  • 16
  • 17
    • 0026479086 scopus 로고
    • Improved prognosis of children with osteosarcoma metastatic to the lung[s] at the time of diagnosis
    • Marina NM, Pratt CB, Rao BN, Shema SJ, Meyer WH. Improved prognosis of children with osteosarcoma metastatic to the lung[s] at the time of diagnosis. Cancer 70(11), 2722-2727 (1992).
    • (1992) Cancer , vol.70 , Issue.11 , pp. 2722-2727
    • Marina, N.M.1    Pratt, C.B.2    Rao, B.N.3    Shema, S.J.4    Meyer, W.H.5
  • 18
    • 0027946691 scopus 로고
    • Pulmonary metastases of stage IIB extremity osteosarcoma and subsequent pulmonary metastases
    • Ward WG, Mikaelian K, Dorey F, et al. Pulmonary metastases of stage IIB extremity osteosarcoma and subsequent pulmonary metastases. J. Clin. Oncol. 12(9), 1849-1858 (1994).
    • (1994) J. Clin. Oncol. , vol.12 , Issue.9 , pp. 1849-1858
    • Ward, W.G.1    Mikaelian, K.2    Dorey, F.3
  • 19
    • 0021638255 scopus 로고
    • Prognostic significance of complete surgical resection of pulmonary metastases in patients with osteogenic sarcoma: Analysis of patients
    • Goorin AM, Delorey MJ, Lack EE, et al. Prognostic significance of complete surgical resection of pulmonary metastases in patients with osteogenic sarcoma: analysis of patients. J. Clin. Oncol. 2(5), 425-431 (1984).
    • (1984) J. Clin. Oncol. , vol.2 , Issue.5 , pp. 425-431
    • Goorin, A.M.1    Delorey, M.J.2    Lack, E.E.3
  • 20
    • 0024575917 scopus 로고
    • Patterns of recurrence after resection of osteosarcoma of the extremity. Strategies for treatment of metastases
    • Huth JF, Eilber FR. Patterns of recurrence after resection of osteosarcoma of the extremity. Strategies for treatment of metastases. Arch. Surg. 124(1), 122-126 (1989).
    • (1989) Arch. Surg. , vol.124 , Issue.1 , pp. 122-126
    • Huth, J.F.1    Eilber, F.R.2
  • 21
    • 0037441937 scopus 로고    scopus 로고
    • Postrelapse survival in osteosarcoma of the extremities: Prognostic factors for long-term survival
    • Ferrari S, Briccoli A, Mercuri M, et al. Postrelapse survival in osteosarcoma of the extremities: prognostic factors for long-term survival. J. Clin. Oncol. 21, 710-715 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 710-715
    • Ferrari, S.1    Briccoli, A.2    Mercuri, M.3
  • 22
    • 0035144560 scopus 로고    scopus 로고
    • Pattern of relapse in patients with osteosarcoma of the extremities treated with neoadjuvant chemotherapy
    • Bacci G, Ferrari S, Longhi A, et al. Pattern of relapse in patients with osteosarcoma of the extremities treated with neoadjuvant chemotherapy. Eur. J. Cancer 37(1), 32-38 (2001).
    • (2001) Eur. J. Cancer , vol.37 , Issue.1 , pp. 32-38
    • Bacci, G.1    Ferrari, S.2    Longhi, A.3
  • 24
    • 0842269770 scopus 로고    scopus 로고
    • The patterns of relapse in osteosarcoma: The Memorial Sloan-Kettering experience
    • Chi SN, Conklin LS, Qin J, et al. The patterns of relapse in osteosarcoma: the Memorial Sloan-Kettering experience. Pediatr. Blood Cancer 42(1), 46-51 (2004).
    • (2004) Pediatr. Blood Cancer , vol.42 , Issue.1 , pp. 46-51
    • Chi, S.N.1    Conklin, L.S.2    Qin, J.3
  • 25
    • 20044389664 scopus 로고    scopus 로고
    • Osteosarcoma relapse after combined modality therapy: An analysis of unselected patients in the Cooperative Osteosarcoma Study Group [COSS]
    • Kempf-Bielack B, Bielack SS, Jürgens H, et al. Osteosarcoma relapse after combined modality therapy: an analysis of unselected patients in the Cooperative Osteosarcoma Study Group [COSS]. J. Clin. Oncol. 23(3), 559-568 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , Issue.3 , pp. 559-568
    • Kempf-Bielack, B.1    Bielack, S.S.2    Jürgens, H.3
  • 26
    • 0014044987 scopus 로고
    • Osteogenic sarcoma. A study of six hundred cases
    • Dahlin DC, Coventry MB. Osteogenic sarcoma. A study of six hundred cases. J. Bone Joint Surg. Am. 49(1), 101-110 (1967).
    • (1967) J. Bone Joint Surg. Am. , vol.49 , Issue.1 , pp. 101-110
    • Dahlin, D.C.1    Coventry, M.B.2
  • 27
  • 28
    • 0016839783 scopus 로고
    • The surgical management of primary osteosarcoma
    • Sweetnam R. The surgical management of primary osteosarcoma. Clin. Orthop. Relat. Res. (111), 57-64 (1975).
    • (1975) Clin. Orthop. Relat. Res. , vol.111 , pp. 57-64
    • Sweetnam, R.1
  • 29
    • 0029070436 scopus 로고
    • Changing pattern of relapse in osteosarcoma of the extremities treated with adjuvant andneoadjuvant chemotherapy
    • Bacci G, Ruggieri P, Picci P, et al. Changing pattern of relapse in osteosarcoma of the extremities treated with adjuvant andneoadjuvant chemotherapy. J. Chemother. 7, 230-239 (1995).
    • (1995) J. Chemother. , vol.7 , pp. 230-239
    • Bacci, G.1    Ruggieri, P.2    Picci, P.3
  • 30
    • 0018890893 scopus 로고
    • Changing indications for bone scintigraphy in patients with osteosarcoma
    • Goldstein H, McNeil BJ, Zufall E, Jaffe N, Treves S. Changing indications for bone scintigraphy in patients with osteosarcoma. Radiology 135(1), 177-180 (1980).
    • (1980) Radiology , vol.135 , Issue.1 , pp. 177-180
    • Goldstein, H.1    McNeil, B.J.2    Zufall, E.3    Jaffe, N.4    Treves, S.5
  • 31
    • 0032953566 scopus 로고    scopus 로고
    • Limb salvage and outcome of osteosarcoma. The University of Muenster experience
    • Lindner NJ, Ramm O, Hillmann A, et al. Limb salvage and outcome of osteosarcoma. The University of Muenster experience. Clin. Orthop. Relat. Res. (358), 83-89 (1999).
    • (1999) Clin. Orthop. Relat. Res. , vol.358 , pp. 83-89
    • Lindner, N.J.1    Ramm, O.2    Hillmann, A.3
  • 32
    • 0032924725 scopus 로고    scopus 로고
    • Local and systemic control after ablative and limb sparing surgery in patients with osteosarcoma
    • Sluga M, Windhager R, Lang S, Heinzl H, Bielack S, Kotz R. Local and systemic control after ablative and limb sparing surgery in patients with osteosarcoma. Clin. Orthop. Relat. Res. (358), 120-127(1999).
    • (1999) Clin. Orthop. Relat. Res. , vol.358 , pp. 120-127
    • Sluga, M.1    Windhager, R.2    Lang, S.3    Heinzl, H.4    Bielack, S.5    Kotz, R.6
  • 33
    • 59149095843 scopus 로고    scopus 로고
    • Second and subsequent recurrences of osteosarcoma: Presentation, treatment, and outcomes of 249 consecutive cooperative osteosarcoma study group patients
    • Bielack SS, Kempf-Bielack B, Branscheid D, et al. Second and subsequent recurrences of osteosarcoma: presentation, treatment, and outcomes of 249 consecutive cooperative osteosarcoma study group patients. J. Clin. Oncol. 27(4), 557-565 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.4 , pp. 557-565
    • Bielack, S.S.1    Kempf-Bielack, B.2    Branscheid, D.3
  • 34
    • 0345707586 scopus 로고    scopus 로고
    • Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy
    • Hawkins DS, Arndt CAS. Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy. Cancer 98(11), 2447-2456 (2003).
    • (2003) Cancer , vol.98 , Issue.11 , pp. 2447-2456
    • Hawkins, D.S.1    Arndt, C.A.S.2
  • 35
    • 0142121407 scopus 로고    scopus 로고
    • Recurrences following primary osteosarcoma in adolescents and adults previously treated with chemotherapy
    • Duffaud F, Digue L, Mercier C, et al. Recurrences following primary osteosarcoma in adolescents and adults previously treated with chemotherapy. Eur. J. Cancer 39(14), 2050-2057 (2003).
    • (2003) Eur. J. Cancer , vol.39 , Issue.14 , pp. 2050-2057
    • Duffaud, F.1    Digue, L.2    Mercier, C.3
  • 37
    • 0026050586 scopus 로고
    • Results of thoracotomy in osteogenic sarcoma with pulmonary metastases
    • Carter SR, Grimer RJ, Sneath RS, Matthews HR. Results of thoracotomy in osteogenic sarcoma with pulmonary metastases. Thorax 46(10), 727-731 (1991).
    • (1991) Thorax , vol.46 , Issue.10 , pp. 727-731
    • Carter, S.R.1    Grimer, R.J.2    Sneath, R.S.3    Matthews, H.R.4
  • 38
    • 0025913250 scopus 로고
    • The contribution of salvage surgery to the management of childhood osteosarcoma
    • Pastorino U, Gasparini M, Tavecchio L, et al. The contribution of salvage surgery to the management of childhood osteosarcoma. J. Clin. Oncol. 9(8), 1357-1362 (1991).
    • (1991) J. Clin. Oncol. , vol.9 , Issue.8 , pp. 1357-1362
    • Pastorino, U.1    Gasparini, M.2    Tavecchio, L.3
  • 39
    • 0030865719 scopus 로고    scopus 로고
    • Osteosarcoma and pulmonary metastases: 15-year experience from a single institution
    • Ellis PM, Tattersall MH, McCaughan B, Stalley P. Osteosarcoma and pulmonary metastases: 15-year experience from a single institution. Aust. NZ J. Surg. 67(9), 625-629 (1997).
    • (1997) Aust. NZ J. Surg. , vol.67 , Issue.9 , pp. 625-629
    • Ellis, P.M.1    Tattersall, M.H.2    McCaughan, B.3    Stalley, P.4
  • 40
    • 77957824053 scopus 로고    scopus 로고
    • High grade osteosarcoma of the extremities metastatic to the lung: Long-term results in patients treated combining surgery and chemotherapy 1985-2005
    • Briccoli A, Rocca M, Salone M, Guzzardella GA, Balladelli A, Bacci G. High grade osteosarcoma of the extremities metastatic to the lung: long-term results in patients treated combining surgery and chemotherapy 1985-2005. Surg. Oncol. 19(4), 193-199 (2010).
    • (2010) Surg. Oncol. , vol.19 , Issue.4 , pp. 193-199
    • Briccoli, A.1    Rocca, M.2    Salone, M.3    Guzzardella, G.A.4    Balladelli, A.5    Bacci, G.6
  • 41
    • 0028245825 scopus 로고
    • Prognostic factors in surgery for pulmonary metastases in children
    • Heij HA, Vos A, de Kraker J, Voute PA. Prognostic factors in surgery for pulmonary metastases in children. Surgery 115(6), 687-693 (1994).
    • (1994) Surgery , vol.115 , Issue.6 , pp. 687-693
    • Heij, H.A.1    Vos, A.2    De Kraker, J.3    Voute, P.A.4
  • 42
    • 0023142606 scopus 로고
    • Thoracotomy for pulmonary metastatic osteosarcoma. An analysis of prognostic indicators of survival
    • Meyer WH, Schell MJ, Kumar AP, et al. Thoracotomy for pulmonary metastatic osteosarcoma. An analysis of prognostic indicators of survival. Cancer 59(2), 374-379 (1987).
    • (1987) Cancer , vol.59 , Issue.2 , pp. 374-379
    • Meyer, W.H.1    Schell, M.J.2    Kumar, A.P.3
  • 43
    • 0019825223 scopus 로고
    • Aggressive thoracotomy for pulmonary metastatic osteogenic sarcoma in children and young adolescents
    • Han MT, Telander RL, Pairolero PC, et al. Aggressive thoracotomy for pulmonary metastatic osteogenic sarcoma in children and young adolescents. J. Pediatr. Surg. 16(6), 928-933 (1981).
    • (1981) J. Pediatr. Surg. , vol.16 , Issue.6 , pp. 928-933
    • Han, M.T.1    Telander, R.L.2    Pairolero, P.C.3
  • 44
    • 0037102214 scopus 로고    scopus 로고
    • Effect of timing of pulmonary metastases identification on prognosis of patients with osteosarcoma: The Japanese Musculoskeletal Oncology Group study
    • Tsuchiya H, Kanazawa Y, Abdel-Wanis ME, et al. Effect of timing of pulmonary metastases identification on prognosis of patients with osteosarcoma: the Japanese Musculoskeletal Oncology Group study. J. Clin. Oncol. 20(16), 3470-3477 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.16 , pp. 3470-3477
    • Tsuchiya, H.1    Kanazawa, Y.2    Abdel-Wanis, M.E.3
  • 45
    • 0030883047 scopus 로고    scopus 로고
    • Long-term follow-up and post-relapse survival in patients with non-metastatic osteosarcoma of the extremity treated with neoadjuvant chemotherapy
    • Ferrari S, Bacci G, Picci P, et al. Long-term follow-up and post-relapse survival in patients with non-metastatic osteosarcoma of the extremity treated with neoadjuvant chemotherapy. Ann. Oncol. 8(8), 765-771 (1997).
    • (1997) Ann. Oncol. , vol.8 , Issue.8 , pp. 765-771
    • Ferrari, S.1    Bacci, G.2    Picci, P.3
  • 47
    • 0015951422 scopus 로고
    • High-dose methotrexate with citrovorum rescue factor and adriamycin in childhood osteogenic sarcoma
    • Rosen G, Suwansirikul S, Kwon C, et al. High-dose methotrexate with citrovorum rescue factor and adriamycin in childhood osteogenic sarcoma. Cancer 33, 1151-1163 (1974).
    • (1974) Cancer , vol.33 , pp. 1151-1163
    • Rosen, G.1    Suwansirikul, S.2    Kwon, C.3
  • 48
    • 0016683624 scopus 로고
    • The management of pulmonary metastases in children with osteogenic sarcoma with surgical resection combined with chemotherapy
    • Beattie E, Martini N, Rosen G. The management of pulmonary metastases in children with osteogenic sarcoma with surgical resection combined with chemotherapy. Cancer 35, 618-621 (1975).
    • (1975) Cancer , vol.35 , pp. 618-621
    • Beattie, E.1    Martini, N.2    Rosen, G.3
  • 49
    • 27644497180 scopus 로고    scopus 로고
    • Treatment of osteosarcoma at first recurrence after contemporary therapy: The Memorial Sloan-Kettering Cancer Center experience
    • Chou AJ, Merola PR, Wexler LH, et al. Treatment of osteosarcoma at first recurrence after contemporary therapy: the Memorial Sloan-Kettering Cancer Center experience. Cancer 104(10), 2214-2149 (2005).
    • (2005) Cancer , vol.104 , Issue.10 , pp. 2214-2149
    • Chou, A.J.1    Merola, P.R.2    Wexler, L.H.3
  • 50
    • 27544499184 scopus 로고    scopus 로고
    • Treatment and outcome of recurrent osteosarcoma: Experience at Rizzoli in patients initially treated with neoadjuvant chemotherapy
    • Bacci G, Briccoli A, longhi A, et al. Treatment and outcome of recurrent osteosarcoma: experience at Rizzoli in patients initially treated with neoadjuvant chemotherapy. Acta Oncol. 44, 748-755 (2005).
    • (2005) Acta Oncol. , vol.44 , pp. 748-755
    • Bacci, G.1    Briccoli, A.2    Longhi, A.3
  • 52
    • 13444253743 scopus 로고    scopus 로고
    • High-dose ifosfamide in relapsed pediatric osteosarcoma: Therapeutic effects and renal toxicity
    • Berrak SG, Pearson M, Berberoglu S, Ilhan IE, Jaffe N. High-dose ifosfamide in relapsed pediatric osteosarcoma: therapeutic effects and renal toxicity. Pediatr Blood Cancer 44(3), 215-219 (2005).
    • (2005) Pediatr Blood Cancer , vol.44 , Issue.3 , pp. 215-219
    • Berrak, S.G.1    Pearson, M.2    Berberoglu, S.3    Ilhan, I.E.4    Jaffe, N.5
  • 53
    • 67649591810 scopus 로고    scopus 로고
    • Phase 2 trial of two courses of cyclophosphamide and etoposide for relapsed high-risk osteosarcoma patients
    • Berger M, Massimo B, Grignani G, et al. Phase 2 trial of two courses of cyclophosphamide and etoposide for relapsed high-risk osteosarcoma patients. Cancer 115(13), 2980-2987 (2009).
    • (2009) Cancer , vol.115 , Issue.13 , pp. 2980-2987
    • Berger, M.1    Massimo, B.2    Grignani, G.3
  • 54
    • 48249154929 scopus 로고    scopus 로고
    • Combination of gemcitabine and docetaxel in the treatment of children and young adults with refractory bone sarcoma
    • Navid F, Willert JR, McCarville MB, Furman W, Watkins A, Roberts W, Daw NC. Combination of gemcitabine and docetaxel in the treatment of children and young adults with refractory bone sarcoma. Cancer 113(2), 419-425 (2008).
    • (2008) Cancer , vol.113 , Issue.2 , pp. 419-425
    • Navid, F.1    Willert, J.R.2    McCarville, M.B.3    Furman, W.4    Watkins, A.5    Roberts, W.6    Daw, N.C.7
  • 55
    • 0036467661 scopus 로고    scopus 로고
    • Prognostic factors in high-grade osteosarcoma of the extremities or trunk: An analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols
    • Bielack SS, Kempf-Bielack B, Delling G, et al. Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols. J. Clin. Oncol. 20(3), 776-790 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.3 , pp. 776-790
    • Bielack, S.S.1    Kempf-Bielack, B.2    Delling, G.3
  • 56
    • 30344488462 scopus 로고    scopus 로고
    • Long-term survival after aggressive resection of pulmonary metastases among children and adolescents with osteosarcoma
    • Harting MT, Blakely ML, Jaffe N, et al. Long-term survival after aggressive resection of pulmonary metastases among children and adolescents with osteosarcoma. J. Pediatr. Surg. 41(1), 194-199 (2006).
    • (2006) J. Pediatr. Surg. , vol.41 , Issue.1 , pp. 194-199
    • Harting, M.T.1    Blakely, M.L.2    Jaffe, N.3
  • 58
    • 33749637891 scopus 로고    scopus 로고
    • Treatment algorithm for locally recurrent osteosarcoma based on local disease-free interval and the presence of lung metastases
    • Nathan SS, Gorlick R, Bukata S, et al. Treatment algorithm for locally recurrent osteosarcoma based on local disease-free interval and the presence of lung metastases. Cancer 107(7), 1607-1616 (2006).
    • (2006) Cancer , vol.107 , Issue.7 , pp. 1607-1616
    • Nathan, S.S.1    Gorlick, R.2    Bukata, S.3
  • 59
    • 0028020606 scopus 로고
    • Relationship of chemotherapy-induced necrosis and surgical margins to local recurrence in osteosarcoma
    • Picci P, Sangiorgi L, Rougraff BT, Neff JR, Casadei R, Campanacci M. Relationship of chemotherapy-induced necrosis and surgical margins to local recurrence in osteosarcoma. J. Clin. Oncol. 12(12), 2699-2705 (1994).
    • (1994) J. Clin. Oncol. , vol.12 , Issue.12 , pp. 2699-2705
    • Picci, P.1    Sangiorgi, L.2    Rougraff, B.T.3    Neff, J.R.4    Casadei, R.5    Campanacci, M.6
  • 60
    • 0030774617 scopus 로고    scopus 로고
    • Risk factors for local recurrences after limb-salvage surgery for high-grade osteosarcoma of the extremities
    • Picci P, Sangiorgi L, Bahamonde L, et al. Risk factors for local recurrences after limb-salvage surgery for high-grade osteosarcoma of the extremities. Ann. Oncol. 8(9), 899-903 (1997).
    • (1997) Ann. Oncol. , vol.8 , Issue.9 , pp. 899-903
    • Picci, P.1    Sangiorgi, L.2    Bahamonde, L.3
  • 62
  • 63
    • 0026349815 scopus 로고
    • Local control and survivalfrom the Cooperative Osteosarcoma Study Group studies of the German Society of Pediatric Oncology and the Vienna Bone Tumor Registry
    • Winkler K, Bieling P, Bielack S, et al. Local control and survivalfrom the Cooperative Osteosarcoma Study Group studies of the German Society of Pediatric Oncology and the Vienna Bone Tumor Registry. Clin. Orthop. Relat. Res. 270, 79-86 (1991).
    • (1991) Clin. Orthop. Relat. Res. , vol.270 , pp. 79-86
    • Winkler, K.1    Bieling, P.2    Bielack, S.3
  • 64
    • 0032813931 scopus 로고    scopus 로고
    • Surgical procedure and local recurrence in 223 patients treated 1982- 1997 according to two osteosarcoma chemotherapy protocols. The Scandinavian Sarcoma Group experience
    • Brosjo O. Surgical procedure and local recurrence in 223 patients treated 1982- 1997 according to two osteosarcoma chemotherapy protocols. The Scandinavian Sarcoma Group experience. Acta. Orthop. Scand. Suppl. 285, 58-61 (1999).
    • (1999) Acta. Orthop. Scand. Suppl. , vol.285 , pp. 58-61
    • Brosjo, O.1
  • 65
    • 34547945108 scopus 로고    scopus 로고
    • Local recurrence and local control of non-metastatic osteosarcoma of the extremities: A 27-year experience in a single institution
    • Bacci G, Forni C, Longhi A, et al. Local recurrence and local control of non-metastatic osteosarcoma of the extremities: a 27-year experience in a single institution. J. Surg. Oncol. 96(2), 118-123 (2007).
    • (2007) J. Surg. Oncol. , vol.96 , Issue.2 , pp. 118-123
    • Bacci, G.1    Forni, C.2    Longhi, A.3
  • 66
    • 2142756852 scopus 로고    scopus 로고
    • Outcome after local recurrence of osteosarcoma:The St. Jude Childrens Research Hospital experience [1970-2000]
    • Rodriguez-Galindo C, Shah N, McCarville MB, et al. Outcome after local recurrence of osteosarcoma:the St. Jude Childrens Research Hospital experience [1970-2000]. Cancer 100(9), 1928-1935 (2004).
    • (2004) Cancer , vol.100 , Issue.9 , pp. 1928-1935
    • Rodriguez-Galindo, C.1    Shah, N.2    McCarville, M.B.3
  • 67
    • 33745194182 scopus 로고    scopus 로고
    • Influence of local recurrence on survival in patients with extremity osteosarcoma treated with neoadjuvant chemotherapy: The experience of a single institution with 44 patients
    • Bacci G, Longhi A, Cesari M, Versari M, Bertoni F. Influence of local recurrence on survival in patients with extremity osteosarcoma treated with neoadjuvant chemotherapy: the experience of a single institution with 44 patients. Cancer 106(12), 2701-2706 (2006).
    • (2006) Cancer , vol.106 , Issue.12 , pp. 2701-2706
    • Bacci, G.1    Longhi, A.2    Cesari, M.3    Versari, M.4    Bertoni, F.5
  • 68
    • 79955505062 scopus 로고    scopus 로고
    • The influence of tumor-and treatment-related factors on the development of local recurrence in osteosarcoma after adequate surgery. An analysis of 1355 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols
    • Andreou D, Bielack SS, Carrle D, et al. The influence of tumor-and treatment-related factors on the development of local recurrence in osteosarcoma after adequate surgery. An analysis of 1355 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols. Ann. Oncol. 22(5), 1228-1235 (2011).
    • (2011) Ann. Oncol. , vol.22 , Issue.5 , pp. 1228-1235
    • Andreou, D.1    Bielack, S.S.2    Carrle, D.3
  • 69
    • 0036163532 scopus 로고    scopus 로고
    • Metachronous multifocal osteosarcoma: A case report and literature review
    • Lee HJ, Kim IO, Kim WS, Cheon JE, Kim KW, Yeon KM. Metachronous multifocal osteosarcoma: a case report and literature review. Clin. Imaging 26(1), 63-68 (2002).
    • (2002) Clin. Imaging , vol.26 , Issue.1 , pp. 63-68
    • Lee, H.J.1    Kim, I.O.2    Kim, W.S.3    Cheon, J.E.4    Kim, K.W.5    Yeon, K.M.6
  • 70
    • 0019514590 scopus 로고
    • Multiple metachronous osteosarcoma with eleven-year survival. A case report
    • Simodynes EE, Jardon OM, Connolly JF. Multiple metachronous osteosarcoma with eleven-year survival. A case report. J. Bone Joint Surg. Am. 63(2), 317-322 (1981).
    • (1981) J. Bone Joint Surg. Am. , vol.63 , Issue.2 , pp. 317-322
    • Simodynes, E.E.1    Jardon, O.M.2    Connolly, J.F.3
  • 72
    • 0037440140 scopus 로고    scopus 로고
    • Metachronous skeletal osteosarcoma in patients treated with adjuvant and neoadjuvant chemotherapy for nonmetastatic osteosarcoma
    • Aung L, Gorlick R, Healey JH, et al. Metachronous skeletal osteosarcoma in patients treated with adjuvant and neoadjuvant chemotherapy for nonmetastatic osteosarcoma. J. Clin. Oncol. 21(2), 342-348 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , Issue.2 , pp. 342-348
    • Aung, L.1    Gorlick, R.2    Healey, J.H.3
  • 73
    • 0345707587 scopus 로고    scopus 로고
    • Single and multiple metachronous osteosarcoma tumors after therapy
    • Jaffe N, Pearson P, Yasko AW, Lin P, Herzog C, Raymond K. Single and multiple metachronous osteosarcoma tumors after therapy. Cancer 98(11), 2457-2466 (2003).
    • (2003) Cancer , vol.98 , Issue.11 , pp. 2457-2466
    • Jaffe, N.1    Pearson, P.2    Yasko, A.W.3    Lin, P.4    Herzog, C.5    Raymond, K.6
  • 74
    • 33748125999 scopus 로고    scopus 로고
    • Bone metastases in osteosarcoma patients treated with neoadjuvant or adjuvant chemotherapy: The Rizzoli experience in 52 patients
    • Bacci G, Longhi A, Bertoni F, et al. Bone metastases in osteosarcoma patients treated with neoadjuvant or adjuvant chemotherapy: the Rizzoli experience in 52 patients. Acta Orthop. 77(6), 938-943 (2006).
    • (2006) Acta Orthop. , vol.77 , Issue.6 , pp. 938-943
    • Bacci, G.1    Longhi, A.2    Bertoni, F.3
  • 76
    • 0036137678 scopus 로고    scopus 로고
    • High-dose samarium-153 ethylene diamine tetramethylene phosphonate: Low toxicity of skeletal irradiation in patients with osteosarcoma and bone metastases
    • Anderson PM, Wiseman GA, Dispenzieri A, et al. High-dose samarium-153 ethylene diamine tetramethylene phosphonate: low toxicity of skeletal irradiation in patients with osteosarcoma and bone metastases. J. Clin. Oncol. 20(1), 189-196 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.1 , pp. 189-196
    • Anderson, P.M.1    Wiseman, G.A.2    Dispenzieri, A.3
  • 77
    • 20244363030 scopus 로고    scopus 로고
    • Osteosarcoma of the pelvis: Experience of the Cooperative Osteosarcoma Study Group
    • Ozaki T, Flege S, Kevric M, et al. Osteosarcoma of the pelvis: experience of the Cooperative Osteosarcoma Study Group. J. Clin. Oncol. 21(2), 334-341 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , Issue.2 , pp. 334-341
    • Ozaki, T.1    Flege, S.2    Kevric, M.3
  • 78
    • 26444443542 scopus 로고    scopus 로고
    • Gemcitabine radiosensitization after high-dose samarium for osteoblastic osteosarcoma
    • Anderson PM, Wiseman GA, Erlandson L, et al. Gemcitabine radiosensitization after high-dose samarium for osteoblastic osteosarcoma. Clin. Cancer Res. 11(19 Pt 1), 6895-6900 (2005).
    • (2005) Clin. Cancer Res. , vol.11 , Issue.19 PART 1 , pp. 6895-6900
    • Anderson, P.M.1    Wiseman, G.A.2    Erlandson, L.3
  • 79
    • 26444584891 scopus 로고    scopus 로고
    • Resection of recurrent pulmonary metastases in patients with osteosarcoma
    • Briccoli A, Rocca M, Salone M, et al. Resection of recurrent pulmonary metastases in patients with osteosarcoma. Cancer 104(8), 1721-1725 (2005).
    • (2005) Cancer , vol.104 , Issue.8 , pp. 1721-1725
    • Briccoli, A.1    Rocca, M.2    Salone, M.3
  • 80
    • 0034993835 scopus 로고    scopus 로고
    • High-dose chemotherapy [HDC] and autologous hematopoietic stem cell transplantation [ASCT] as salvage therapy for relapsed osteosarcoma
    • Sauerbrey A, Bielack S, Kempf-Bielack B, Zoubek A, Paulussen M, Zintl F. High-dose chemotherapy [HDC] and autologous hematopoietic stem cell transplantation [ASCT] as salvage therapy for relapsed osteosarcoma. Bone Marrow Transplant. 27, 933-937 (2001).
    • (2001) Bone Marrow Transplant. , vol.27 , pp. 933-937
    • Sauerbrey, A.1    Bielack, S.2    Kempf-Bielack, B.3    Zoubek, A.4    Paulussen, M.5    Zintl, F.6
  • 81
    • 0037089598 scopus 로고    scopus 로고
    • High-dose chemotherapy in the treatment of relapsed osteosarcoma: An Italian sarcoma group study
    • Fagioli F, Aglietta M, Tienghi A, et al. High-dose chemotherapy in the treatment of relapsed osteosarcoma: an Italian sarcoma group study. J. Clin. Oncol. 20(8), 2150-2156 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.8 , pp. 2150-2156
    • Fagioli, F.1    Aglietta, M.2    Tienghi, A.3
  • 82
    • 0035668596 scopus 로고    scopus 로고
    • High-activity samarium-153-EDTMP therapy followed by autologous peripheral blood stem cell support in unresectable osteosarcoma
    • Franzius C, Bielack S, Flege S, et al. High-activity samarium-153-EDTMP therapy followed by autologous peripheral blood stem cell support in unresectable osteosarcoma. Nuklearmedizin 40(6), 215-220 (2001).
    • (2001) Nuklearmedizin , vol.40 , Issue.6 , pp. 215-220
    • Franzius, C.1    Bielack, S.2    Flege, S.3
  • 83
    • 0028928375 scopus 로고
    • Efficacy of liposomal muramyl tripeptide [CGP 19835A] in the treatment of relapsed osteosarcoma
    • Kleinerman ES, Gano JB, Johnston DA, Benjamin RS, Jaffe N. Efficacy of liposomal muramyl tripeptide [CGP 19835A] in the treatment of relapsed osteosarcoma. Am. J. Clin. Oncol. 18(2), 93-99 (1995).
    • (1995) Am. J. Clin. Oncol. , vol.18 , Issue.2 , pp. 93-99
    • Kleinerman, E.S.1    Gano, J.B.2    Johnston, D.A.3    Benjamin, R.S.4    Jaffe, N.5
  • 84
    • 77955122716 scopus 로고    scopus 로고
    • Inhaled granulocyte-macrophage colony stimulating factor for first pulmonary recurrence of osteosarcoma: Effects on disease-free survival and immunomodulation. A report from the Childrens Oncology Group
    • Arndt CAS, Koshkina NV, Inwards CY, et al. Inhaled granulocyte-macrophage colony stimulating factor for first pulmonary recurrence of osteosarcoma: effects on disease-free survival and immunomodulation. a report from the Childrens Oncology Group. Clin. Cancer Res. 16(15), 4024-4030 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , Issue.15 , pp. 4024-4030
    • Arndt, C.A.S.1    Koshkina, N.V.2    Inwards, C.Y.3
  • 85
    • 13344285355 scopus 로고    scopus 로고
    • ErbB-2 expression is correlated with poor prognosis for patients with osteosarcoma
    • Onda M, Matsuda S, Higaki S, et al. ErbB-2 expression is correlated with poor prognosis for patients with osteosarcoma. Cancer 77(1), 71-78 (1996).
    • (1996) Cancer , vol.77 , Issue.1 , pp. 71-78
    • Onda, M.1    Matsuda, S.2    Higaki, S.3
  • 86
    • 84873702613 scopus 로고    scopus 로고
    • Inhaled lipid cisplatin [ILC] in the treatment of patients with relapsed/progressive osteosarcoma metastatic to the lung
    • Chou AJ, Gupta R, Bell MD, Riewe KO, Meyers PA, Gorlick R. Inhaled lipid cisplatin [ILC] in the treatment of patients with relapsed/progressive osteosarcoma metastatic to the lung. Pediatr. Blood Cancer 60(4), 580-586 (2013).
    • (2013) Pediatr. Blood Cancer , vol.60 , Issue.4 , pp. 580-586
    • Chou, A.J.1    Gupta, R.2    Bell, M.D.3    Riewe, K.O.4    Meyers, P.A.5    Gorlick, R.6
  • 87
    • 2342477964 scopus 로고    scopus 로고
    • Ezrin, a key component in tumor metastasis
    • Hunter KW. Ezrin, a key component in tumor metastasis. Trends Mol. Med. 10(5), 201-204 (2004).
    • (2004) Trends Mol. Med. , vol.10 , Issue.5 , pp. 201-204
    • Hunter, K.W.1
  • 88
    • 11144357298 scopus 로고    scopus 로고
    • The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
    • Khanna C, Wan X, Bose S, et al. The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis. Nat. Med. 10(2), 182-186 (2004).
    • (2004) Nat. Med. , vol.10 , Issue.2 , pp. 182-186
    • Khanna, C.1    Wan, X.2    Bose, S.3
  • 89
    • 9744235167 scopus 로고    scopus 로고
    • Increased Fas expression reduces the metastatic potential of human osteosarcoma cells
    • Lafleur EA, Koshkina NV, Stewart J, et al. Increased Fas expression reduces the metastatic potential of human osteosarcoma cells. Clin. Cancer Res. 10(23), 8114-8119 (2004).
    • (2004) Clin. Cancer Res. , vol.10 , Issue.23 , pp. 8114-8119
    • Lafleur, E.A.1    Koshkina, N.V.2    Stewart, J.3
  • 90
    • 28144441402 scopus 로고    scopus 로고
    • Fas expression in lung metastasis from osteosarcoma patients
    • Gordon N, Arndt CAS, Hawkins DS, et al. Fas expression in lung metastasis from osteosarcoma patients. J. Pediatr. Hematol. Oncol. 27(11), 611-615 (2005).
    • (2005) J. Pediatr. Hematol. Oncol. , vol.27 , Issue.11 , pp. 611-615
    • Gordon, N.1    Arndt, C.A.S.2    Hawkins, D.S.3
  • 91
    • 26444583306 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor [PEDF]-induced apoptosis and inhibition of vascular endothelial growth factor [VEGF] expression in MG63 human osteosarcoma cells
    • Takenaka K, Yamagishi S-I, Jinnouchi Y, Nakamura K, Matsui T, Imaizumi T. Pigment epithelium-derived factor [PEDF]-induced apoptosis and inhibition of vascular endothelial growth factor [VEGF] expression in MG63 human osteosarcoma cells. Life Sci. 77(25), 3231-3241 (2005).
    • (2005) Life Sci. , vol.77 , Issue.25 , pp. 3231-3241
    • Takenaka, K.1    Yamagishi, S.-I.2    Jinnouchi, Y.3    Nakamura, K.4    Matsui, T.5    Imaizumi, T.6
  • 92
    • 80755128482 scopus 로고    scopus 로고
    • Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model
    • Broadhead ML, Dass CR, Choong PFM. Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model. Br. J. Cancer 105(10), 1503-1511 (2011).
    • (2011) Br. J. Cancer , vol.105 , Issue.10 , pp. 1503-1511
    • Broadhead, M.L.1    Dass, C.R.2    Choong, P.F.M.3
  • 93
    • 0034896298 scopus 로고    scopus 로고
    • The expression of the urokinase plasminogen activator system in metastatic murine osteosarcoma: An in vivo mouse model
    • Fisher JL, Mackie PS, Howard ML, Zhou H, Choong PF. The expression of the urokinase plasminogen activator system in metastatic murine osteosarcoma: an in vivo mouse model. Clin. Cancer Res. 7(6), 1654-1660 (2001).
    • (2001) Clin. Cancer Res. , vol.7 , Issue.6 , pp. 1654-1660
    • Fisher, J.L.1    Mackie, P.S.2    Howard, M.L.3    Zhou, H.4    Choong, P.F.5
  • 94
    • 33747473703 scopus 로고    scopus 로고
    • Downregulation of uPAR confirms link in growth and metastasis of osteosarcoma
    • Dass CR, Nadesapillai APW, Robin D, et al. Downregulation of uPAR confirms link in growth and metastasis of osteosarcoma. Clin. Exp. Metastasis. 22(8), 643-652 (2005).
    • (2005) Clin. Exp. Metastasis. , vol.22 , Issue.8 , pp. 643-652
    • Dass, C.R.1    Nadesapillai, A.P.W.2    Robin, D.3
  • 95
    • 0025346003 scopus 로고
    • Primary chemotherapy and delayed surgery [neoadjuvant chemotherapy] for osteosarcoma of the extremities. The Istituto Rizzoli Experience in 127 patients treated preoperatively with intravenous methotrexate [high versus moderate doses] and intraarterial cisplatin
    • Bacci G, Picci P, Ruggieri P, et al. Primary chemotherapy and delayed surgery [neoadjuvant chemotherapy] for osteosarcoma of the extremities. The Istituto Rizzoli Experience in 127 patients treated preoperatively with intravenous methotrexate [high versus moderate doses] and intraarterial cisplatin. Cancer 65(11), 2539-2553 (1990).
    • (1990) Cancer , vol.65 , Issue.11 , pp. 2539-2553
    • Bacci, G.1    Picci, P.2    Ruggieri, P.3
  • 96
    • 22244439824 scopus 로고    scopus 로고
    • Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases
    • Koshkina NV, Kleinerman ES. Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases. Int. J. Cancer 116(3), 458-463 (2005).
    • (2005) Int. J. Cancer , vol.116 , Issue.3 , pp. 458-463
    • Koshkina, N.V.1    Kleinerman, E.S.2
  • 97
    • 84867320849 scopus 로고    scopus 로고
    • Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor
    • 126906
    • Federman N, Chan J, Nagy JO, et al. Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor. Sarcoma 2012, 126906 (2012).
    • (2012) Sarcoma , vol.2012
    • Federman, N.1    Chan, J.2    Nagy, J.O.3
  • 99
    • 67651160326 scopus 로고    scopus 로고
    • A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy
    • Ta HT, Dass CR, Larson I, Choong PF, Dunstan DE. A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy. Biomaterials 30(27), 4815-4823 (2009).
    • (2009) Biomaterials , vol.30 , Issue.27 , pp. 4815-4823
    • Ta, H.T.1    Dass, C.R.2    Larson, I.3    Choong, P.F.4    Dunstan, D.E.5
  • 100
    • 18344390219 scopus 로고    scopus 로고
    • Increased pre-therapeutic serum vascular endothelial growth factor in patients with early clinical relapse of osteosarcoma
    • Kaya M, Wada T, Kawaguchi S, et al. Increased pre-therapeutic serum vascular endothelial growth factor in patients with early clinical relapse of osteosarcoma. Br. J. Cancer 86(6), 864-869 (2002).
    • (2002) Br. J. Cancer , vol.86 , Issue.6 , pp. 864-869
    • Kaya, M.1    Wada, T.2    Kawaguchi, S.3
  • 101
    • 71049161801 scopus 로고    scopus 로고
    • VEGF expression as a prognostic marker in osteosarcoma
    • Bajpai J, Sharma M, Sreenivas V, Kumar R, et al. VEGF expression as a prognostic marker in osteosarcoma. Pediatr. Blood Cancer 53(6), 1035-1039 (2009).
    • (2009) Pediatr. Blood Cancer , vol.53 , Issue.6 , pp. 1035-1039
    • Bajpai, J.1    Sharma, M.2    Sreenivas, V.3    Kumar, R.4
  • 102
    • 0028946970 scopus 로고
    • Suppression of pulmonary metastasis by angiogenesis inhibitor TNP-470 in murine osteosarcoma
    • Mori S, Ueda T, Kuratsu S, Hosono N, Izawa K, Uchida A. Suppression of pulmonary metastasis by angiogenesis inhibitor TNP-470 in murine osteosarcoma. Int. J. Cancer. 61(1), 148-152 (1995).
    • (1995) Int. J. Cancer. , vol.61 , Issue.1 , pp. 148-152
    • Mori, S.1    Ueda, T.2    Kuratsu, S.3    Hosono, N.4    Izawa, K.5    Uchida, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.