Lack of a therapeutic role for interferon in patients with tuberculosis

Journal of Infectious Diseases

Volumn 209, Issue 4, 2014, Pages 627-628

  Wallis, Robert S ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

HUMANS; INTERFERON-GAMMA; MACROPHAGES; MYCOBACTERIUM TUBERCULOSIS;

EID: 84893259336     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jit555     Document Type: Letter

References (10)

1. Wong KW, Jacobs WR Jr. Mycobacterium tuberculosis exploits human interferon γ to stimulate macrophage extracellular trap formation and necrosis. J Infect Dis 2013; 208: 109-19.
2. Condos R, Rom WN, Schluger NW. Treatment of multidrug-resistant pulmonary tuberculosis with interferon-gamma via aerosol. Lancet 1997; 349:1513-5.
3. Suarez-Mendez R, Garcia-Garcia I, Fernandez-Olivera N, et al. Adjuvant interferon gamma in patients with drug-resistant pulmonary tuberculosis: a pilot study. BMC Infect Dis 2004; 4:44.
4. Koh WJ, Kwon OJ, Suh GY, et al. Six-month therapy with aerosolized interferon-gamma for refractory multidrug-resistant pulmonary tuberculosis. J Korean Med Sci 2004; 19:167-71.
5. Dawson R, Condos R, Tse D, et al. Immunomodulation with recombinant interferongamma1b in pulmonary tuberculosis. PLoS One 2009; 4:e6984.
6. InterMune enrolls first patient in phase III trial in multidrug-resistant tuberculosis. BusinessWire. 2000. http://www.thefreelibrary. com/InterMune+Enrolls+First+Patient+in +Phase+III+Trial+in...-a063778269. Accessed 22 October 2013.
7. Wallis RS, Wang C, Doherty TM, et al. Biomarkers for tuberculosis disease activity, cure, and relapse. Lancet Infect Dis 2010; 10: 68-9.
8. Horne DJ, Royce SE, Gooze L, et al. Sputum monitoring during tuberculosis treatment for predicting outcome: a systematic review and meta-analysis. Lancet Infect Dis 2010; 10:387-94.
9. Phillips PP, Fielding K, Nunn AJ. An evaluation of culture results during treatment for tuberculosis as surrogate endpoints for treatment failure and relapse. PLoS One 2013; 8: e63840.
10. Raju B, Hoshino Y, Kuwabara K, et al. Aerosolized gamma interferon (IFN-gamma) induces expression of the genes encoding the IFNgamma-inducible 10-kilodalton protein but not inducible nitricoxidesynthaseinthelungduring tuberculosis. Infect Immun 2004; 72:1275-83.