Inflammatory myopathy with anti-SRP antibodies: case series of a South Australian cohort

Clinical Rheumatology

Volumn 34, Issue 3, 2015, Pages 603-608

  Basnayake, Sajini K ^a   Blumbergs, Peter ^b   Tan, Ju Ann ^c   Roberts Thompson, Peter J ^b,c,d   Limaye, Vidya ^a,b  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c FLINDERS MEDICAL CENTRE   (Australia)

^d Immunology Department   (Australia)

Author keywords

Histopathology; Muscle biopsy; Myositis; Necrotizing myopathy; Polymyositis; SRP antibodies

Indexed keywords

SIGNAL RECOGNITION PARTICLE;

CASE REPORT; HUMAN; IMMUNOLOGY; MALE; MIDDLE AGED; MUSCLE; MYOSITIS; PATHOLOGY; VERY ELDERLY;

AGED, 80 AND OVER; HUMANS; MALE; MIDDLE AGED; MUSCLES; MYOSITIS; SIGNAL RECOGNITION PARTICLE;

EID: 84893181148     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-014-2512-7     Document Type: Review

References (21)

1. Karin R, Frederick Miller W, Bernhard D, Stephen H (2006) Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages. Arthritis Res Ther 8:R39
2. Kao AH, Lacomis D, Lucas M, Fertig N, Oddis CV (2004) Anti-signal recognition particle autoantibody in patients with and patients without idiopathic inflammatory myopathy. Arthritis Rheum 50:209–215
3. Brouwer R, Hengstman GJ, Vree Egberts W, Ehrfeld H, Bozic B, Ghirardello A et al (2001) Autoantibody profiles in the sera of European patients with myositis. Ann Rheum Dis 60:116–123
4. Targoff IN, Johnson AE, Miller FW (1990) Antibody to signal recognition particle in polymyositis. Arthritis Rheum 33:1361–1370
5. Miller T, Al-Lozi MT, Lopate G, Pestronk A (2002) Myopathy with antibodies to the signal recognition particle: clinical and pathological features. J Neurol Neurosurg Psychiatry 73:420–428
6. Ira N, Targoff, Arthur Johnson E, Frederick Miller W (1990) Antibody to signal recognition particle in polymyositis. Arthritis Rheum 33:1361–1370
7. Hengstman GJ, Ter Laak HJ, Vree Egberts WT, Lundberg IE, Moutsopoulos HM, Vencovsky J et al (2006) Anti-SRP autoantibodies, marker of a necrotizing myopathy. Ann Rheum Dis 65:1635–1638
8. Hengstman GJ, Brouwer R, Egberts WT, Seelig HP, Jongen PJ, van Venrooij WJ (2002) Clinical and serological characteristics of 125 Dutch myositis patients: myositis specific autoantibodies aid in the differential diagnosis of the idiopathic inflammatory myopathies. J Neurol 249:69–75
9. Love LA, Leff RL, Fraser DD, Targoff IN, Dalakas M, Plotz PH, Miller FW (1991) A new approach to the classification of idiopathic inflammatory myopathy: myositis-specific autoantibodies define useful homogeneous groups. Medicine 70:360–374
10. Hausmanowa-Petrusewicz I, Kowalska-Oledzka E, Miller FW, Jarzabek CM, Targoff IN, Blaszczyk KM et al (1997) Clinical, serologic, and immunogenetic features in Polish patients with idiopathic inflammatory myopathy. Arthritis Rheum 40:1257–1266
11. Benveniste O, Drouot L, Jouen F, Charuel JL, Bloch-Queyrat C, Behin A, Amoura Z, Marie I, Guiguet M, Eymard B, Gilbert D, Tron F, Herson S, Musset L, Boyer O (2011) Anti-signal recognition particle auto-antibody levels correlate with creatine kinase activity in patients with necrotizing myopathy. Arthritis Rheum
12. Valiyil R, Casciola-Rosen L, Hong G, Mammen A, Christopher-Stine L (2010) Rituximab therapy for myopathy associated with anti-signal recognition particle antibodies: a case series. Arthritis Care Res 62(9):1328–1334
13. Sultan SM, Ng KP, Edwards JC, Isenberg DA, Cambridge G (2008) Clinical outcome following B cell depletion therapy in eight patients with refractory inflammatory myopathy. Clin Exp Rheumatol 26:887–893
14. Hohlfeld R (2002) Polymyositis and dermatomyositis. In: Karpati G (ed) Structural and molecular basis of skeletal muscle disease. ISN Neuropath Press, Switzerland, pp 221–227
15. Dalakas MC (2011) Pathophysiology of inflammatory and autoimmune myopathies. Press Med 40:e237–e247
16. Chahin N, Engel AG (2008) Correlation of muscle biopsy, clinical course, and outcome in PM and sporadic IBM. Neurology 70:418–424
17. Mastalgia FL, Philips VA (2002) Idiopathic inflammatory myopathies, epidemiology, classification and diagnostic criteria. Rheum Dis Clin North Am 28:723–741
18. Suzuki S, Satoh T, Sato S, Otomo M, Hirayama Y, Sato H, Kawai M, Ishihara T, Suzuki N, Kuwana M (2008) Clinical utility of anti-signal recognition particle antibody in the differential diagnosis of myopathies. Rheumatology (Oxford) 47(10):1539–1542
19. Benveniste O, Drouot L, Jouen F, Charuel JL, Bloch-Queyrat C, Behin A, Amoura Z, Marie I, Guiguet M, Eymard B, Gilbert D, Tron F, Herson S, Musset L, Boyer O (2011) Correlation of anti-signal recognition particle autoantibody levels with creatine kinase activity in patients with necrotizing myopathy. Arthritis Rheum 63(7):1961–1971
20. Rönnelid J, Barbasso Helmers S, Storfors H, Grip K, Rönnblom L, Franck-Larsson K, Nordmark G, Lundberg IE (2009) Use of a commercial line blot assay as a screening test for autoantibodies in inflammatory myopathies. Autoimmun Rev 9(1):58–61
21. Ghirardello A, Rampudda ME, Bassi N, Zampieri S, Grypiotis P, Bendo R, Arienti S, Tonon G, Lundberg IE, Doria A (2008) Serological testing in myositis patients: diagnostic accuracy of a commercial line blot assay. 6. International Congress on Autoimmunity, Porto