Possible role of the α7 nicotinic receptors in mediating nicotine's effect on developing lung - implications in unexplained human perinatal death

BMC Pulmonary Medicine

Volumn 14, Issue 1, 2014, Pages

  Lavezzi, Anna M ^a   Corna, Melissa F ^a   Alfonsi, Graziella ^a   Matturri, Luigi ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Brainstem; Human lung development; Maternal smoking in pregnancy; Nicotine; Nicotinic receptors; SIDS; SIUDS

Indexed keywords

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; FEMALE; FETAL DEATH; HUMANS; INFANT, NEWBORN; LUNG; MALE; MATERNAL BEHAVIOR; NICOTINE; PREGNANCY; SMOKING; SUDDEN INFANT DEATH;

EID: 84893180866     PISSN: None     EISSN: 14712466     Source Type: Journal    
DOI: 10.1186/1471-2466-14-11     Document Type: Article

References (44)

1. Mathews TJ. Smoking during pregnancy, 1990-1996. Natl Vital Stat Rep 1998, 47:1-12.
2. Wainright RL. Change in observed birth weight associated with change in maternal cigarette smoking. Am J Epidemiol 1983, 117:668-675.
3. Aliyu MH, Salihu HM, Wilson RE, Kirby RS. Prenatal smoking and risk of intrapartum stillbirth. Arch Environ Occup Health 2007, 62:87-92. 10.3200/AEOH.62.2.87-92, 18316266.
4. Kleinman JC, Pierre MBJ, Madans JH, Land GH, Schramm WF. The effects of maternal smoking on fetal and infant mortality. Am J Epidemiol 1988, 127:274-282.
5. Taylor B, Wadsworth J. Maternal smoking during pregnancy and lower respiratory tract illness in early life. Arch Dis Child 1987, 62:786-791. 10.1136/adc.62.8.786, 1778463, 3662581.
6. Julvez J, Ribas-Fito N, Torrent M, Forns M, Garcia-Esteban R, Sunyer J. Maternal smoking habits and cognitive development of children at age 4 years in a population-based birth cohort. Int J Epidemiol 2007, 36:825-832. 10.1093/ije/dym107, 17550944.
7. Luck W, Nau H, Hansen R, Steldinger R. Extent of nicotine and cotinine transfer to the human fetus, placenta and amniotic fluid of smoking mothers. Dev Pharmacol Ther 1985, 8:384-395.
8. Lindstrom J. Nicotinic acetylcholine receptors in health and disease. Mol Neurobiol 1997, 15:193-222. 10.1007/BF02740634, 9396010.
9. Boyd RT. The molecular biology of neuronal nicotinic acetylcholine receptors. Crit Rev Toxicol 1997, 27:299-318. 10.3109/10408449709089897, 9189657.
10. Albuquerque EX, Pereira EF, Alkondon M, Rogers SW. Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol Rev 2009, 89:73-120. 10.1152/physrev.00015.2008, 2713585, 19126755.
11. Fowler CD, Arends MA, Kenny PJ. Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. Behav Pharmacol 2008, 19:461-484. 10.1097/FBP.0b013e32830c360e, 2669417, 18690103.
12. Itier V, Bertrand D. Neuronal nicotinic receptors: from protein structure to function. FEBS Lett 2001, 504:118-125. 10.1016/S0014-5793(01)02702-8, 11532443.
13. Gotti C, Clementi F, Fornari A, Gaimarri A, Guiducci S, Manfredi I, Moretti M, Pedrazzi P, Pucci L, Zoli M. Structural and functional diversity of native brain neuronal nicotinic receptors. Biochem Pharmacol 2009, 78:703-711. 10.1016/j.bcp.2009.05.024, 19481063.
14. Dwyer JB, McQuown SC, Leslie FM. The dynamic effects of nicotine on the developing brain. Pharmacol Ther 2009, 122:125-139. 10.1016/j.pharmthera.2009.02.003, 2746456, 19268688.
15. Graham A, Court JA, Martin-Ruiz CM, Jaros E, Perry R, Volsen SG, Bose S, Evans N, Ince P, Kuryatov A, Lindstrom J, Gotti C, Perry EK. Immunohistochemical localisation of nicotinic acetylcholine receptor subunits in human cerebellum. Neuroscience 2002, 113:493-507. 10.1016/S0306-4522(02)00223-3, 12150770.
16. Wessler I, Kirkpatrick CJ. Acetylcholine beyond neurons: the Non-neuronal cholinergic system in humans. Brit J Pharmacol 2008, 154:1558-1571.
17. Spindel ER. Neuronal nicotinic acetylcholine receptors: not just in brain. Am J Physiol Lung Cell Mol Physiol 2003, 285:1201-1202.
18. Fu XW, Lindstrom J, Spindel ER. Nicotine activates and up-regulates nicotinic acetylcholine receptors in bronchial epithelial cells. Am J Physiol Lung Cell Mol Biol 2009, 41:93-99.
19. Sekhon HS, Jia Y, Raab R, Kuryatov A, Pankow JF, Whitsett JA, Lindstrom J, Spindel ER. Prenatal nicotine increases pulmonary alpha7 nicotinic receptor expression and alters fetal lung development in monkeys. J Clin Invest 1999, 103:637-647. 10.1172/JCI5232, 408124, 10074480.
20. Sekhon HS, Keller JA, Benowitz NL, Spindel ER. Prenatal nicotine exposure alters pulmonary function in newborn rhesus monkeys. Am J Respir Crit Care Med 2001, 164:989-994. 10.1164/ajrccm.164.6.2011097, 11587984.
21. Matturri L, Lavezzi AM, Cappellini A, Ottaviani G, Minoli I, Rubino B, Rossi L. Association between pulmonary hypoplasia and hypoplasia of arcuate nucleus in stillbirth. J Perinatol 2003, 23:328-332.
22. Ottaviani G, Mingrone R, Lavezzi AM, Matturri L. Infant and perinatal pulmonary hypoplasia frequently associated with brainstem hypodevelopment. Virchows Arch 2009, 454:451-456. 10.1007/s00428-009-0754-6, 19288128.
23. Matturri L, Ottaviani G, Lavezzi AM. Techniques and criteria in pathologic and forensic-medical diagnostics of sudden unexpected infant and perinatal death. Am J Clin Pathol 2005, 124:259-268. 10.1309/J6AREY41HKBEYVHX, 16040298.
24. Matturri L, Ottaviani G, Lavezzi AM. Guidelines for neuropathologic diagnostics of perinatal unexpected loss and sudden infant death syndrome (SIDS): a technical protocol. Virchows Arch 2008, 452:19-25. 10.1007/s00428-007-0527-z, 18034263.
25. Emery JL, Mithal A. The number of alveoli in the terminal respiratory unit of man during late intrauterine life and childhood. Arch Dis Child 1960, 35:544-547. 10.1136/adc.35.184.544, 2012643, 13726619.
26. Landis RJ, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977, 33:159-174. 10.2307/2529310, 843571.
27. Hornung JP. The human raphe nuclei and the serotonergic system. J Chem Neuroanat 2003, 26:331-343. 10.1016/j.jchemneu.2003.10.002, 14729135.
28. Lavezzi AM, Matturri L. Hypoplasia of the parafacial/facial complex: a very frequent finding in sudden unexplained fetal death. Open Neurosci J 2008, 2008(2):1-5.
29. Lavezzi AM, Ottaviani G, Rossi L, Matturri L. Hypoplasia of the Parabrachial/Kölliker-Fuse complex in perinatal death. Biol Neonate 2004, 86:92-97. 10.1159/000078310, 15118341.
30. Lavezzi AM, Matturri L. Functional neuroanatomy of the human pre-Bötzinger complex with particular reference to sudden unexplained perinatal and infant death. Neuropathology 2008, 28:10-16. 10.1111/j.1440-1789.2007.00824.x, 18031468.
31. Matturri L, Minoli I, Lavezzi AM, Cappellini A, Ramos S, Rossi L. Hypoplasia of medullary arcuate nucleus in unexpected late fetal death (stillborn infants): a pathologic study. Pediatrics 2002, 109:E43. 10.1542/peds.109.3.e43, 11875171.
32. Kajekar R. Environmental factors and developmental outcomes in the lung. Pharmacol Therap 2007, 114:129-145.
33. Burri PH. Fetal and postnatal development of the lung. Annu Rev Physiol 1984, 46:617-628. 10.1146/annurev.ph.46.030184.003153, 6370120.
34. Maritz GS, Windvogel S. Chronic maternal nicotine exposure during gestation and lactation and the development of the lung parenchyma in the offspring. Response to nicotine withdrawal. Pathophysiology 2003, 10:69-75. 10.1016/j.pathophys.2003.10.001, 14643906.
35. Frank L, Sosenko IR. Prenatal development of lung antioxidant enzymes in four species. J Pediatr 1987, 110:106-110. 10.1016/S0022-3476(87)80300-1, 3794868.
36. Stepans MB, Wilkerson N. Physiologic effects of maternal smoking on breast-feeding infants. J Am Acad Nurse Pract 1993, 5:105-113. 10.1111/j.1745-7599.1993.tb00850.x, 8347401.
37. Wongtrakool C, Wang N, Hyde DM, Roman J, Spindel ER. Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors. Am J Respir Cell Mol Biol 2012, 46:695-702. 10.1165/rcmb.2011-0028OC, 3359906, 22246862.
38. Schuller HM, Jull BA, Sheppard BJ, Plummer HK. Interaction of tobacco-specific toxicants with the neuronal α7 nicotinic acetylcholine receptor and its associated mitogenic signal transduction pathway: potential role in lung carcinogenesis and pediatric lung disorders. Eur J Pharmacol 2000, 393:265-277. 10.1016/S0014-2999(00)00094-7, 10771023.
39. Paleari L, Catassi A, Ciarlo M, Cavalieri Z, Bruzzo C, Servent D, Cesario A, Chessa L, Cilli M, Piccardi F, Granone P, Russo P. Role of alpha7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation. Cell Prolif 2008, 41:936-959. 10.1111/j.1365-2184.2008.00566.x, 19040571.
40. Shacka JJ, Robinson SE. Exposure to prenatal nicotine transiently increases neuronal nicotinic receptor subunit α7, α4 and β2 messenger RNASs in the postnatal rat brain. Neuroscience 1998, 84:1151-1161. 10.1016/S0306-4522(97)00564-2, 9578402.
41. Plummer HK, Dhar M, Schuller HM. Expression of the alpha7 nicotinic acetylcholine receptor in human lung cells. Respir Res 2005, 6:29-37. 10.1186/1465-9921-6-29, 1079948, 15807899.
42. Sekhon HS, Proskocil BJ, Clark JA, Spindel ER. Prenatal nicotine exposure increases connective tissue expression in foetal monkey pulmonary vessels. Eur Respir J 2004, 23:906-915. 10.1183/09031936.04.00069604, 15219006.
43. Bearer C, Emerson RK, O'Riordan MA, Roitman E, Shackleton C. Maternal tobacco smoke exposure and persistent pulmonary hypertension of the newborn. Environ Health Perspect 1997, 105:202-206. 10.1289/ehp.97105202, 1469798, 9105795.
44. Heath AC, Knopik VS, Madden PA, Neuman RJ, Lynskey MJ, Slutske WS, Jacob T, Martin NG. Accuracy of mothers' retrospective reports of smoking during pregnancy: comparison with twin sister informant rating. Twin Res 2003, 6:297-301. 10.1375/136905203322296656, 14511436.