The expression and clinical significance of β-catenin and colorectal cancer stem cells marker EpCAMhigh/CD44+ in colorectal cancer

Chinese-German Journal of Clinical Oncology

Volumn 12, Issue 12, 2013, Pages

  Liu, Dan ^a   Sun, Jinghua ^a   Zhu, Jinming ^b   Zhou, Huan ^a   Zhang, Yang ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b DALIAN UNIVERSITY   (China)

Author keywords

catenin; Cancer stem cells; Double immunohistochemical staining; EpCAMhigh CD44+

Indexed keywords

BETA CATENIN; EPITHELIAL CELL ADHESION MOLECULE; HERMES ANTIGEN; WNT PROTEIN;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER RECURRENCE; CANCER STAGING; CANCER STEM CELL; CELL INVASION; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR INVASION;

EID: 84893142121     PISSN: 16101979     EISSN: 16139089     Source Type: Journal    
DOI: 10.1007/s10330-013-1258-z     Document Type: Article

References (15)

1. Shi H, Li SJ, Zhang B, et al. Expression of MSP58 in human colorectal cancer and its correlation with prognosis. Med Oncol, 2012, 29: 3136-42.
2. Wu XZ. Origin of cancer stem cells: the role of self-renewal and differentiation. Ann Surg Oncol, 2008, 15: 407-414.
3. Li Z, Liu CP, He YL, et al. The expression and significance of multidrug resistance genes in breast cancer stem cells. Chinese-German J Clin Oncol, 2008, 7: 538-541.
4. Yang YM, Chang JW. Current status and issues in cancer stem cell study. Cancer Invest, 2008, 26: 741-755.
5. Kanwar SS, Yu Y, Nautiyal J, et al. The Wnt/β-catenin pathway regulates growth and maintenance of colono spheres. Mol Cancer, 2010, 9: 212.
6. Nodin B, Johannesson H, Wangefjord S, et al. Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer. Diagn Pathol, 2012, 7: 115.
7. Al-Hajj M, Wicha M S, Benito-Hernandez A, et al. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A, 2003, 100: 3983-3988.
8. Khramtsov AI, Khramtsova GF, Tretiakova M, et al. Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome. Am J Pathol, 2010, 176: 2911-2920.
9. Wang L, Cheng H, Liu Y, et al. Prognostic value of nuclear β-catenin overexpression at invasive front in colorectal cancer for synchronous liver metastasis. Ann Surg Oncol, 2011, 18: 1553-1559.
10. Dylla SJ, Beviglia L, Park IK, et al. Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. PLoS One, 2008, 3: e2428.
11. Langan RC, Mullinax JE, Ray S, et al. A pilot study assessing the potential role of non-CD133 colorectal cancer stem cells as biomarkers. J Cancer, 2012, 3: 231-240.
12. Marhaba R, Klingbell P, Nuebel T, et al. CD44 and EpCAM: cancerinitiating cell markers. Curr Mol Med, 2008, 8: 784-804.
13. Mikryukov A, Moss T. Agonistic and antagonistic roles for TNIK and MINK in non-Canonical and canonical Wnt signalling. PLoS One, 2012, 7: e43330.
14. Leushacke M, Spörle R, Bernemann C, et al. An RNA interference phenotypic screen identifies a role for FGF signals in colon cancer progression. PLoS One, 2011, 6: e23381.
15. Guo Q, Xia B, Zhang F, et al. Tetraspanin CO-029 inhibits colorectal cancer cell movement by deregulating cell-matrix and cell-cell adhesions. PLoS One, 2012, 7: e38464.