Ordering of polypeptides in liquid crystals, gels and micelles

Advances in Polymer Science

Volumn 259, Issue , 2013, Pages 159-200

  Cai, Chunhua ^a   Lin, Jiaping ^a   Zhuang, Zeliang ^a   Zhu, Wenjie ^a  

^a East China University of Science and Technology   (China)

Author keywords

Gels; Liquid crystals; Micelles; Ordered structure; Polypeptide; Self assembly

Indexed keywords

EID: 84893090605     PISSN: 00653195     EISSN: None     Source Type: Book Series    
DOI: 10.1007/12_2013_221     Document Type: Article

References (142)

1. Deming TJ (1997) Polypeptide materials: new synthetic methods and applications. Adv Mater 9:299-311
2. Mart RJ, Osborne RD, Stevens URV (2006) Peptide-based stimuli-responsive biomaterials. Soft Matter 2:822-835
3. Osada K, Kataoka K (2006) Drug and gene delivery based on supramolecular assembly of PEG-polypeptide hybrid block copolymers. Adv Polym Sci 202:113-153
4. Schlaad H (2006) Solution properties of polypeptide-based copolymers. Adv Polym Sci 202:53-73
5. Carlsen A, Lecommandoux S (2009) Self-assembly of polypeptide-based block copolymer amphiphiles. Curr Opin Colloid Interface Sci 14:329-339
6. Deming TJ (2007) Synthetic polypeptides for biomedical applications. Prog Polym Sci 32:858-875
7. Banwell EF, Abelardo ES, Adams DJ, Birchall MA, Corrigan A (2009) Rational design and application of responsive α-helical peptide hydrogels. Nat Mater 8:596-600
8. He C, Zhuang X, Tang Z, Tian H, Chen X (2012) Stimuli-sensitive synthetic polypeptidebased materials for drug and gene delivery. Adv Healthc Mater 1:48-78
9. Lowik DWPM, Leunissen EHP, van den Heuvel M, Hansen MB, van Hest JCM (2010) Stimulus responsive peptide based materials. Chem Soc Rev 39:3394-3412
10. Choe U-J, Sun VZ, Tan JKY, Kamei DT (2012) Self-assembly polypeptide and polypeptide hybrid vesicles: from synthesis to application. Top Curr Chem 310:117-134
11. Chow D, Nunalee ML, Lim DW, Simnick AJ, Chilkoti A (2008) Peptide-based biopolymers in biomedicine and biotechnology. Mater Sci Eng R Rep 62:125-155
12. Lim Y-b, Lee E, Lee M (2007) Cell-penetrating-peptide-coated nanoribbons for intracellular nanocarriers. Angew Chem Int Ed 46:3475-3478
13. Kopecek J, Yang J (2012) Smart self-assembled hybrid hydrogel biomaterials. Angew Chem Int Ed 51:7396-7417
14. Higashihara T, Ueda M (2011) Block copolymers containing rod segments. In: Hadjichristidis N, Hirao A, Tezuka Y, Du Prez F (eds) Complex macromolecular architectures: synthesis, characterization, and self-assembly. Wiley, Hoboken, pp 395-429
15. Klok H-A (2002) Protein-inspired materials: synthetic concepts and potential applications. Angew Chem Int Ed 41:1509-1513
16. Zhang G, Fournier MJ, Mason TL, Tirrell DA (1992) Biological synthesis of monodisperse derivatives of poly(α, L-glutamic acid): model rodlike polymers. Macromolecules 25:3601-3603
17. Rabotyagova OS, Cebe P, Kaplan DL (2011) Protein-based block copolymers. Biomacromolecules 12:269-289
18. Kiick KL (2002) Genetic methods of polymer synthesis. In: Mark HF (ed) Encyclopedia of polymer science and technology. Wiley, Hoboken, pp 515-522
19. Merrifield RB (1963) Solid phase peptide synthesis. I. The synthesis of a tetrapeptide. J Am Chem Soc 85:2149-2154
20. Aliferis T, Iatrou H, Hadjichristidis N (2004) Living polypeptides. Biomacromolecules 5:1653-1656
21. Hadjichristidis N, Iatrou H, Pitsikalis M, Sakellariou G (2009) Synthesis of well-defined polypeptide-based materials via the ring-opening polymerization of alpha-amino acid N-carboxyanhydrides. Chem Rev 109:5528-5578
22. Kricheldorf HR (2006) Polypeptides and 100 years of chemistry of α-amino acid N-carboxyanhydrides. Angew Chem Int Ed 45:5752-5784
23. Kricheldorf HR (1987) α-aminoacid-N-carboxy-anhydrides and related heterocycles: syntheses, properties, peptide synthesis, polymerization. Springer, Berlin
24. Penczek S, Kricheldorf HR (1990) Models of biopolymers by ring opening polymerization. CRC, Boca Raton
25. Duran H, Ogura K, Nakao K, Vianna SDB, Usui H (2009) High-vacuum vapor deposition and in situ monitoring of N-carboxy anhydride benzyl glutamate polymerization. Langmuir 25:10711-10718
26. Leuchs H, Geiger W (1908) The anhydrides of alpha-amino-N-carboxylic and alpha-amino acids. Ber Dtsch Chem Ges 41:1721-1726
27. Voet D, Voet JG (eds) (1995) Biochemistry, Solutions Manual. Wiley, Hoboken
28. Zimm BH, Bragg JK (1959) Theory of the phase transition between helix and random coil in polypeptide chains. J Chem Phys 31:526-535
29. Teramoto A, Fujita H (1975) Conformation-dependent properties of synthetic polypeptides in the helix-coil transition region. Adv Polym Sci 18:65-149
30. Parras P, Castelletto V, Hamley IW, Klok H-A (2005) Nanostructure formation in poly (γ-benzyl-L-glutamate)-poly(ethylene glycol)-poly(γ-benzyl-L-glutamate) triblock copolymers in the solid state. Soft Matter 1:284-291
31. Hadjichristidis N, Iatrou H, Pitsikalis M, Pispas S, Avgeropoulos A (2005) Linear and non-linear triblock terpolymers: synthesis, self-assembly in selective solvents and in bulk. Prog Polym Sci 30:725-782
32. Klok H-A, Lecommandoux S (2006) Solid-state structure, organization and properties of peptide-synthetic hybrid block copolymers. Adv Polym Sci 202:75-111
33. Sanchez-Ferrer A, Mezzenga R (2010) Secondary structure-induced micro-and macrophase separation in rod-coil polypeptide diblock, triblock, and star-block copolymers. Macromolecules 43:1093-1100
34. Babin J, Taton D, Brinkmann M, Lecommandoux S (2008) Synthesis and self-assembly in bulk of linear and mikto-arm star block copolymers based on polystyrene and poly(glutamic acid). Macromolecules 41:1384-1392
35. Kopecek J, Yang J (2009) Peptide-directed self-assembly of hydrogels. Acta Biomater 5:805-816
36. Hermes F, Otte K, Brandt J, Grawert M, Borner HG, Schlaad H (2011) Polypeptide-based organogelators: effects of secondary structure. Macromolecules 44:7489-7492
37. Huang C-J, Chang F-C (2008) Polypeptide diblock copolymers: syntheses and properties of poly(N-isopropylacrylamide)-b-polylysine. Macromolecules 41:7041-7052
38. Gebhardt KE, Ahn S, Venkatachalam G, Savin DA (2008) Role of secondary structure changes on the morphology of polypeptide-based block copolymer vesicles. J Colloid Interface Sci 317:70-76
39. Robinson C (1956) Liquid-crystalline structures in solutions of a polypeptide. Trans Faraday Soc 52:571-592
40. Uematsu I, Uematsu Y (1984) Polypeptide liquid crystals. Adv Polym Sci 59:37-73
41. Flory PJ, Leonard WJ (1965) Thermodynamic properties of solutions of helical polypeptides. J Am Chem Soc 87:2102-2108
42. Tohyama K, Miller WG (1981) Network structure in gels of rod-like polypeptides. Nature 289:813-814
43. Cohen Y (1996) The microfibrillar network in gels of poly(γ-benzyl- L-glutamate) in benzyl alcohol. J Polym Sci, Part B: Polym Phys 34:57-64
44. Kim KT, Park C, Vandermeulen GWM, Rider DA, Kim C, Winnik MA, Manners I (2005) Gelation of helical polypeptide-random coil diblock copolymers by a nanoribbon mechanism. Angew Chem Int Ed 44:7964-7968
45. Rodriguez-Hernandez J, Lecommandoux S (2005) Reversible inside-out micellization of pH-responsive and water-soluble vesicles based on polypeptide diblock copolymers. J Am Chem Soc 127:2026-2027
46. Holowka EP, Pochan DJ, Deming TJ (2005) Charged polypeptide vesicles with controllable diameter. J Am Chem Soc 127:12423-12428
47. Bellomo EG, Wyrsta MD, Pakstis L, Pochan DJ, Deming TJ (2004) Stimuli-responsive polypeptide vesicles by conformation-specific assembly. Nat Mater 3:244-248
48. Kim KT, Park C, Kim C, Winnik MA, Manners I (2006) Self-assembly of dendron-helical polypeptide copolymers: organogels and lyotropic liquid crystals. Chem Commun 1372-1374
49. Yu SM, Conticello VP, Zhang G, Kayser C, Fournier MJ, Mason TL, Tirrell DA (1997) Smectic ordering in solutions and films of a rod-like polymer owing to monodispersity of chain length. Nature 389:167-170
50. Schmidtke S, Russo P, Nakamatsu J, Buyuktanir E, Turfan B, Temyanko E, Negulescu I (2000) Thermoreversible gelation of isotropic and liquid crystalline solutions of a "sticky" rodlike polymer. Macromolecules 33:4427-4432
51. Ginzburg B, Siromyatnikova T, Frenkel S (1985) Gelation in the poly(γ-benzyl-L-glutamate)-dimethylformamide system. Polym Bull (Berl) 13:139-144
52. Russo PS, Magestro P, Miller WG (1987) Gelation of poly(γ-benzyl- α,L-glutamate). In: Russo PS (ed) Reversible polymeric gels and related systems. ACS symposium series, vol 350. American Chemical Society, Washington, DC, pp 152-180
53. Kuo S-W, Lee H-F, Huang W-J, Jeong K-U, Chang F-C (2009) Solid state and solution selfassembly of helical polypeptides tethered to polyhedral oligomeric silsesquioxanes. Macromolecules 42:1619-1626
54. Kim EH, Joo MK, Bahk KH, Park MH, Chi B, Lee YM, Jeong B (2009) Reverse thermal gelation of PAF-PLX-PAF block copolymer aqueous solution. Biomacromolecules 10:2476-2481
55. Li T, Lin J, Chen T, Zhang S (2006) Polymeric micelles formed by polypeptide graft copolymer and its mixtures with polypeptide block copolymer. Polymer 47:4485-4489
56. Cai C, Zhang L, Lin J, Wang L (2008) Self-assembly behavior of pH-and thermosensitive amphiphilic triblock copolymers in solution: experimental studies and self-consistent field theory simulations. J Phys Chem B 112:12666-12673
57. Ueda M, Makino A, Imai T, Sugiyama J, Kimura S (2011) Transformation of peptide nanotubes into a vesicle via fusion driven by stereo-complex formation. Chem Commun 47:3204-3206
58. Cai C, Wang L, Lin J (2011) Self-assembly of polypeptide-based copolymers into diverse aggregates. Chem Commun 47:11189-11203
59. Kim MS, Dayananda K, Choi EY, Park HJ, Kim JS, Lee DS (2009) Synthesis and characterization of poly(L-glutamic acid)-block-poly(L-phenylalanine). Polymer 50:2252-2257
60. Schenck HL, Gellman SH (1998) Use of a designed triple-stranded antiparallel β-sheet to probe β-sheet cooperativity in aqueous solution. J Am Chem Soc 120:4869-4870
61. Ding W, Lin S, Lin J, Zhang L (2008) Effect of chain conformational change on micelle structures: experimental studies and molecular dynamics simulations. J Phys Chem B 112:776-783
62. Lin J, Zhu G, Zhu X, Lin S, Nose T, Ding W (2008) Aggregate structure change induced by intramolecular helix-coil transition. Polymer 49:1132-1136
63. Kotharangannagari VK, Sanchez-Ferrer A, Ruokolainen J, Mezzenga R (2012) Thermoreversible gel-sol behavior of rod-coil-rod peptide-based triblock copolymers. Macromolecules 45:1982-1990
64. Yu SM, Soto CM, Tirrell DA (2000) Nanometer-scale smectic ordering of genetically engineered rodlike polymers: synthesis and characterization of monodisperse derivatives of poly(γ-benzyl α, L-glutamate). J Am Chem Soc 122:6552-6559
65. Sasaki S, Tokuma K, Uematsu I (1983) Phase behavior of poly(γ-benzyl L-glutamate) solutions in benzyl alcohol. Polym Bull (Berl) 10:539-546
66. Watanabe J, Takashina Y (1991) Columnar liquid crystals in polypeptides. 1. A columnar hexagonal liquid crystal observed in poly(γ-octadecyl L-glutamate). Macromolecules 24:3423-3426
67. Robinson C, Ward JC (1957) Liquid-crystalline structures in polypeptides. Nature 180:1183-1184
68. Robinson C (1961) Liquid-crystalline structures in polypeptide solutions. Tetrahedron 13:219-234
69. Robinson C, Ward JC, Beevers RB (1958) Liquid crystalline structure in polypeptide solutions. Part 2. Discuss Faraday Soc 25:29-42
70. Samulski ET, Tobolsky AV (1967) Solid "liquid crystal" films of poly-γ-benzyl-L-glutamate. Nature 216:997
71. Elliott A, Ambrose EJ (1950) Evidence of chain folding in polypeptides and proteins. Discuss Faraday Soc 9:246-251
72. Marx A, Thiele C (2009) Orientational properties of poly-γ-benzyl- L-glutamate: influence of molecular weight and solvent on order parameters of the solute. Chem Eur J 15:254-260
73. Watanabe J, Nagase T (1988) Thermotropic polypeptides. 5. Temperature dependence of cholesteric pitches exhibiting a cholesteric sense inversion. Macromolecules 21:171-175
74. Toriumi H, Kusumi Y, Uematsu I, Uematsu Y (1979) Thermally induced inversion of the cholesteric sense in lyotropic polypeptide liquid crystals. Polym J 11:863-869
75. Toriumi H, Minakuchi S, Uematsu Y, Uematsu I (1980) Helical twisting power of poly (γ-benzyl-L-glutamate) liquid crystals in mixed solvents. Polym J 12:431-437
76. Abe A, Hiraga K, Imada Y, Hiejima T, Furuya H (2005) Screw-sense inversion characteristic of α-helical poly(β-p-chlorobenzyl L-aspartate) and comparison with other related polyaspartates. Peptide Sci 80:249-257
77. Abe A, Furuya H, Okamoto S (1997) Spatial configurations, transformation, and reorganization of mesophase structures of polyaspartates-a highly intelligent molecular system. Peptide Sci 43:405-412
78. Abe A, Imada Y, Furuya H (2010) Mechanism of the screw-sense reversal of tightly hydrogen-bonded α-helical network triggered by the side-chain conformation. Polymer 51:6234-6239
79. Junnila S, Houbenov N, Hanski S, Iatrou H, Hirao A, Hadjichristidis N, Ikkala O (2010) Hierarchical smectic self-assembly of an ABC miktoarm star terpolymer with a helical polypeptide arm. Macromolecules 43:9071-9076
80. Lin J (1997) Re-entrant isotropic transition of polypeptide liquid crystal. Polymer 38:4837-4841
81. Lin J (1998) Reentrant isotropic transition of polypeptide liquid crystal: effect of steric and orientation-dependent interactions. Polymer 39:5495-5500
82. Lin J, Abe A, Furuya H, Okamoto S (1996) Liquid crystal formation coupled with the coilhelix transition in the ternary system poly(γ-benzyl L-glutamate)/dichloroacetic acid/dichloroethane. Macromolecules 29:2584-2589
83. Lin J, Lin S, Liu P, Hiejima T, Furuya H, Abe A (2003) Phase behavior of ternary systems involving a conformationally variable chain and a randomly coiled polymer. Macromolecules 36:6267-6272
84. Flory PJ (1984) Molecular theory of liquid crystals. Adv Polym Sci 59:1-36
85. Abe A, Ballauff M (1991) The Flory lattice model. In: Ciferri A (ed) Liquid crystallinity in polymers: principles and fundamental properties. Wiley-VCH, Weinheim, Chap. 4
86. Lin J, Lin S, Zhang L, Nose T (2009) Microphase separation of rod-coil diblock copolymer in solution. J Chem Phys 130:094907
87. Watanabe J, Imai K, Uematsu I (1978) Light scattering studies of poly(γ-benzyl L-glutamate) solutions and films. Polym Bull 1:67-72
88. Tadmor R, Khalfin RL, Cohen Y (2002) Reversible gelation in isotropic solutions of the helical polypeptide poly(γ-benzyl-L-glutamate): kinetics and formation mechanism of the fibrillar network. Langmuir 18:7146-7150
89. Tipton DL, Russo PS (1996) Thermoreversible gelation of a rodlike polymer. Macromolecules 29:7402-7411
90. Oikawa H, Nakanishi H (2001) Dynamics of probe particles during sol-gel transition of PBLG-DMF solution and the resulting gel structure. J Chem Phys 115:3785-3791
91. Niehoff A, Mantion A, McAloney R, Huber A (2013) Elucidation of the structure of poly (γ-benzyl-L-glutamate) nanofibers and gel networks in a helicogenic solvent. Colloid Polym Sci 291:1353-1363
92. Kishi R, Sisido M, Tazuke S (1990) Liquid-crystalline polymer gels. 1. Cross-linking of poly (γ-benzyl L-glutamate) in the cholesteric liquid-crystalline state. Macromolecules 23:3779-3784
93. Kishi R, Sisido M, Tazuke S (1990) Liquid-crystalline polymer gels. 2. Anisotropic swelling of poly(γ-benzyl L-glutamate) gel crosslinked under a magnetic field. Macromolecules 23:3868-3870
94. Inomata K, Iguchi Y, Mizutani K, Sugimoto H, Nakanishi E (2012) Anisotropic swelling behavior induced by helix-coil transition in liquid crystalline polypeptide gels. ACS Macro Lett 1:807-810
95. Gibson MI, Cameron NR (2008) Organogelation of sheet-helix diblock copolypeptides. Angew Chem Int Ed 47:5160-5162
96. Choi YY, Jeong Y, Joo MK, Jeong B (2009) Reverse thermal organogelation of poly(ethylene glycol)-polypeptide diblock copolymers in chloroform. Macromol Biosci 9:869-874
97. Naik SS, Savin DA (2009) Poly(Z-lysine)-based organogels: effect of interfacial frustration on gel strength. Macromolecules 42:7114-7121
98. Sun J, Chen X, Guo J, Shi Q, Xie Z, Jing X (2009) Synthesis and self-assembly of a novel Y-shaped copolymer with a helical polypeptide arm. Polymer 50:455-461
99. You Y, Chen Y, Hua C, Dong C (2010) Synthesis and thermoreversible gelation of dendronlike polypeptide/linear poly(ε-caprolactone)/dendron- like polypeptide triblock copolymers. J Polym Sci A Polym Chem 48:709-718
100. Borner HG, Smarsly BM, Hentschel J, Rank A, Schubert R, Geng Y, Discher DE, Hellweg T, Brandt A (2008) Organization of self-assembled peptide-polymer nanofibers in solution. Macromolecules 41:1430-1437
101. van Bommel KJC, Friggeri A, Shinkai S (2003) Organic templates for the generation of inorganic materials. Angew Chem Int Ed 42:980-999
102. Sone ED, Zubarev ER, Stupp SI (2002) Semiconductor nanohelices templated by supramolecular ribbons. Angew Chem Int Ed 41:1705-1709
103. Estroff LA, Addadi L, Weiner S, Hamilton AD (2004) An organic hydrogel as a matrix for the growth of calcite crystals. Org Biomol Chem 2:137-141
104. Shumburo A, Biewer MC (2002) Stabilization of an organic photochromic material by incorporation in an organogel. Chem Mater 14:3745-3750
105. Deming TJ (2005) Polypeptide hydrogels via a unique assembly mechanism. Soft Matter 1:28-35
106. Breedveld V, Nowak AP, Sato J, Deming TJ, Pine DJ (2004) Rheology of block copolypeptide solutions: hydrogels with tunable properties. Macromolecules 37:3943-3953
107. Nowak AP, Breedveld V, Pakstis L, Ozbas B, Pine DJ, Pochan D, Deming TJ (2002) Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles. Nature 417:424-428
108. Nowak AP, Breedveld V, Pine DJ, Deming TJ (2003) Unusual salt stability in highly charged diblock co-polypeptide hydrogels. J Am Chem Soc 125:15666-15670
109. Pakstis LM, Ozbas B, Hales KD, Nowak AP, Deming TJ, Pochan D (2003) Effect of chemistry and morphology on the biofunctionality of self-assembling diblock copolypeptide hydrogels. Biomacromolecules 5:312-318
110. Oliveira ED, Hirsch SG, Spontak RJ, Gehrke SH (2003) Influence of polymer conformation on the shear modulus and morphology of polyallylamine and poly(α-L-lysine) hydrogels. Macromolecules 36:6189-6201
111. Choi BG, Park MH, Cho S-H, Joo MK, Oh HJ, Kim EH, Park K, Han DK, Jeong B (2011) Thermal gelling polyalanine-poloxamine-polyalanine aqueous solution for chondrocytes 3D culture: initial concentration effect. Soft Matter 7:456-462
112. Chen Y, Pang X, Dong C (2010) Dual stimuli-responsive supramolecular polypeptide-based hydrogel and reverse micellar hydrogel mediated by host-guest chemistry. Adv Funct Mater 20:579-586
113. Cheng Y, He C, Xiao C, Ding J, Zhuang X, Huang Y, Chen X (2012) Decisive role of hydrophobic side groups of polypeptides in thermosensitive gelation. Biomacromolecules 13:2053-2059
114. Altunbas A, Pochan D (2012) Peptide-based and polypeptide-based hydrogels for drug delivery and tissue engineering. Adv Polym Sci 310:135-167
115. Aggeli A, Nyrkova IA, Bell M, Harding R, Carrick L, McLeish TCB, Semenov AN, Boden N (2001) Hierarchical self-assembly of chiral rod-like molecules as a model for peptide β-sheet tapes, ribbons, fibrils, and fibers. Proc Natl Acad Sci USA 98:11857-11862
116. Smeenk JM, Otten MBJ, Thies J, Tirrell DA, Stunnenberg HG, van Hest JCM (2005) Controlled assembly of macromolecular β-Sheet fibrils. Angew Chem Int Ed 44:1968-1971
117. Choi YY, Joo MK, Sohn YS, Jeong B (2008) Significance of secondary structure in nanostructure formation and thermosensitivity of polypeptide block copolymers. Soft Matter 4:2383-2387
118. Choi YY, Jang JH, Park MH, Choi BG, Chi B, Jeong B (2010) Block length affects secondary structure, nanoassembly and thermosensitivity of poly(ethylene glycol)-poly(L-alanine) block copolymers. J Mater Chem 20:3416-3421
119. Petka WA, Harden JL, McGrath KP, Wirtz D, Tirrell DA (1998) Reversible hydrogels from self-assembling artificial proteins. Science 281:389-392
120. Eloi J-C, Rider DA, Cambridge G, Whittell GR, Winnik MA, Manners I (2011) Stimulusresponsive self-assembly: reversible, redox-controlled micellization of polyferrocenylsilane diblock copolymers. J Am Chem Soc 133:8903-8913
121. Ho R-M, Chiang Y-W, Lin S-C, Chen C-K (2011) Helical architectures from self-assembly of chiral polymers and block copolymers. Prog Polym Sci 36:376-453
122. Lin J, Zhu J, Chen T, Lin S, Cai C, Zhang L, Zhuang Y, Wang X-S (2009) Drug releasing behavior of hybrid micelles containing polypeptide triblock copolymer. Biomaterials 30:108-117
123. Fuks G, Mayap Talom R, Gauffre F (2011) Biohybrid block copolymers: towards functional micelles and vesicles. Chem Soc Rev 40:2475-2493
124. Qian J, Zhang M, Manners I, Winnik MA (2010) Nanofiber micelles from the self-assembly of block copolymers. Trends Biotechnol 28:84-92
125. Cauet SI, Lee NS, Lin LY, Wooley KL (2012) Individual nano-objects obtained via hierarchical assembly of polymer building blocks. In: Matyjaszewski K, Moller M (eds) Polymer science: a comprehensive reference. Elsevier, Amsterdam, pp 775-820
126. Feng C, Li Y, Yang D, Hu J, Zhang X, Huang X (2011) Well-defined graft copolymers: from controlled synthesis to multipurpose applications. Chem Soc Rev 40:1282-1295
127. Bian Q, Xiao Y, Lang M (2012) Thermoresponsive biotinylated star amphiphilic block copolymer: synthesis, self-assembly, and specific target recognition. Polymer 53:1684-1693
128. Cai C, Wang L, Lin J, Zhang X (2012) Morphology transformation of hybrid micelles selfassembled from rod-coil block copolymer and nanoparticles. Langmuir 28:4515-4524
129. Cai C, Zhu W, Chen T, Lin J, Tian X (2009) Synthesis and self-assembly behavior of amphiphilic polypeptide-based brush-coil block copolymers. J Polym Sci A Polym Chem 47:5967-5978
130. Koga T, Taguchi K, Kobuke Y, Kinoshita T, Higuchi M (2003) Structural regulation of a peptide-conjugated graft copolymer: a simple model for amyloid formation. Chem Eur J 9:1146-1156
131. Tang D, Lin J, Lin S, Zhang S, Chen T, Tian X (2004) Self-assembly of poly(γ-benzyl L-glutamate)-graft-poly(ethylene glycol) and its mixtures with poly(γ-benzyl L-glutamate) homopolymer. Macromol Rapid Commun 25:1241-1246
132. Marsden HR, Handgraaf J-W, Nudelman F, Sommerdijk NAJM, Kros A (2010) Uniting polypeptides with sequence-designed peptides: synthesis and assembly of poly (γ-benzyl L-glutamate)-b-coiled-coil peptide copolymers. J Am Chem Soc 132:2370-2377
133. Huang J, Bonduelle C, Thevenot J, Lecommandoux S, Heise A (2012) Biologically active polymersomes from amphiphilic glycopeptides. J Am Chem Soc 134:119-122
134. Checot F, Lecommandoux S, Gnanou Y, Klok HA (2002) Water-soluble stimuli-responsive vesicles from peptide-based diblock copolymers. Angew Chem Int Ed 41:1339-1343
135. Sun J, Chen X, Deng C, Yu H, Xie Z, Jing X (2007) Direct formation of giant vesicles from synthetic polypeptides. Langmuir 23:8308-8315
136. Schatz C, Louguet S, Le Meins J-F, Lecommandoux S (2009) Polysaccharide-block-polypeptide copolymer vesicles: towards synthetic viral capsids. Angew Chem Int Ed 48:2572-2575
137. Holowka EP, Sun VZ, Kamei DT, Deming TJ (2007) Polyarginine segments in block copolypeptides drive both vesicular assembly and intracellular delivery. Nat Mater 6:52-57
138. Cai C, Lin J, Chen T, Tian X (2010) Aggregation behavior of graft copolymer with rigid backbone. Langmuir 26:2791-2797
139. Zhuang Z, Zhu X, Cai C, Lin J, Wang L (2012) Self-assembly of a mixture system containing polypeptide graft and block copolymers: experimental studies and self-consistent field theory simulations. J Phys Chem B 116:10125-10134
140. Cornelissen JJLM, Fischer M, Sommerdijk NAJM, Nolte RJM (1998) Helical superstructures from charged poly(styrene)-poly(isocyanodipeptide) block copolymers. Science 280:1427-1430
141. Cai C, Lin J, Chen T, Wang X, Lin S (2009) Super-helices self-assembled from a binary system of amphiphilic polypeptide block copolymers and polypeptide homopolymers. Chem Commun 2709-2711
142. Bull SR, Palmer LC, Fry NJ, Greenfield M, Messmore B, Meade T, Stupp SI (2008) A templating approach for monodisperse self-assembled organic nanostructures. J Am Chem Soc 130:2742-2743