Statistical power of multilevel modelling in dental caries clinical trials: A simulation study

Caries Research

Volumn 48, Issue 1, 2014, Pages 13-18

  Burnside, G ^a   Pine, C M ^b   Williamson, P R ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Multilevel modelling; Randomised controlled trials; Statistical analysis

Indexed keywords

ANTICARIES AGENT; CHLORHEXIDINE; FLUORIDE VARNISH; PLACEBO; TOPICAL ANTIINFECTIVE AGENT;

ADOLESCENT; ALGORITHM; BINOMIAL DISTRIBUTION; CHILD; CLINICAL TRIAL (TOPIC); COMPARATIVE STUDY; COMPUTER SIMULATION; DENTAL CARIES; HEALTH SURVEY; HUMAN; INTERVENTION STUDY; MULTILEVEL ANALYSIS; PROCEDURES; SAMPLE SIZE; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; TREATMENT OUTCOME;

ADOLESCENT; ALGORITHMS; ANTI-INFECTIVE AGENTS, LOCAL; BINOMIAL DISTRIBUTION; CARIOSTATIC AGENTS; CHILD; CHLORHEXIDINE; CLINICAL TRIALS AS TOPIC; COMPUTER SIMULATION; DENTAL CARIES; DMF INDEX; FLUORIDES, TOPICAL; HUMANS; INTERVENTION STUDIES; LIKELIHOOD FUNCTIONS; LOGISTIC MODELS; MULTILEVEL ANALYSIS; PLACEBOS; SAMPLE SIZE; TREATMENT OUTCOME;

EID: 84893088184     PISSN: 00086568     EISSN: None     Source Type: Journal    
DOI: 10.1159/000351642     Document Type: Article

References (20)

1. Ahn C, Jung SH, Donner A: Application of an adjusted chi2 statistic to site-specific data in observational dental studies. J Clin Periodontol 2002; 29:79-82. (Pubitemid 41697738)
2. Begg MD: Analysis of correlated responses; in Lesaffre E, Feine J, Leroux BG, Declerck D (eds): Statistical and Methodological Aspects of Oral Health Research. Chichester, Wiley, 2009.
3. Browne WJ, Draper D: A comparison of Bayesian and likelihood-based methods for fitting multilevel models. Bayesian Anal 2006; 1:473-514.
4. Burnside G, Pine CM, Williamson PR: Statistical aspects of design and analysis of clinical trials for the prevention of caries. Caries Res 2006; 40:360-365. (Pubitemid 44329043)
5. Burnside G, Pine CM, Williamson PR: The application of multilevel modelling to dental caries data. Stat Med 2007; 26:4139-4149. (Pubitemid 47399344)
6. Donner A, Klar N: Design and Analysis of Cluster Randomization Trials in Health Research. London, Arnold, 2000.
7. Forgie AH, Paterson M, Pine CM, Pitts NB, Nugent ZJ: A randomised controlled trial of the caries-preventive efficacy of a chlorhexidine-containing varnish in high-caries-risk adolescents. Caries Res 2000; 34:432-439.
8. Gilthorpe MS, Maddick IH, Petrie A: Introduction to multilevel modelling in dental research. Community Dent Health 2000; 17: 222-226.
9. Goldstein H: Multilevel mixed linear model analysis using iterative generalized least squares. Biometrika 1986; 73:43-56.
10. Goldstein H: Multilevel Statistical Models, ed 3. London, Arnold, 2003.
11. Goldstein H, Rasbash J: Improved approximations for multilevel models with binary responses. J R Stat Soc Ser A 1996; 159:505-513. (Pubitemid 126333155)
12. Hannigan A, O'Mullane DM, Barry D, Schafer F, Roberts AJ: A re-analysis of a caries clinical trial by survival analysis. J Dent Res 2001; 80: 427-431. (Pubitemid 32378946)
13. Hausen H: How to improve the effectiveness of caries-preventive programs based on fluoride. Caries Res 2004; 38:263-267. (Pubitemid 38716220)
14. Ismail AI: Visual and visuo-tactile detection of dental caries. J Dent Res 2004; 83:C56-C66. (Pubitemid 44126045)
15. Macfarlane TV, Worthington HV: Some aspects of data analysis in dentistry. Community Dent Health 1999; 16:216-219.
16. Mancl LA, Hujoel PP, DeRouen TA: Efficiency issues among statistical methods for demonstrating efficacy of caries prevention. J Dent Res 2004; 83(Spec No C):C95-C98. (Pubitemid 44126048)
17. Marinho VC, Higgins JP, Logan S, Sheiham A: Topical fluoride (toothpastes, mouthrinses, gels or varnishes) for preventing dental caries in children and adolescents. Cochrane Database Syst Rev 2003; 4:CD002782.
18. Rasbash J, Steele F, Browne W, Prosser B: A User's Guide to MLwiN Version 2.0. Bristol, Centre for Multilevel Modelling, 2005.
19. Stephenson J, Chadwick BL, Playle RA, Treasure ET: Modelling childhood caries using parametric competing risks survival analysis methods for clustered data. Caries Res 2010; 44:69-80.
20. Wong MC, Lam KF, Lo EC: Analysis of multilevel grouped survival data with time-varying regression coefficients. Stat Med 2011; 30: 250-259.