First-trimester exposure to methylphenidate: A population-based cohort study

Journal of Clinical Psychiatry

Volumn 75, Issue 1, 2014, Pages

  Pottegard, Anton ^a,b   Hallas, Jesper ^a,b   Andersen, Jon T ^c   Løkkegaard, Ellen C L ^d   Dideriksen, Dorthe ^a   Aagaard, Lise ^a   Damkier, Per ^a,b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

^c BISPEBJERG HOSPITAL   (Denmark)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; ATOMOXETINE; DEXAMPHETAMINE; METHYLPHENIDATE; MODAFINIL; NEUROLEPTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT;

ARTICLE; ATTENTION DEFICIT DISORDER; BODY MASS; COHORT ANALYSIS; CONGENITAL HEART MALFORMATION; CONGENITAL MALFORMATION; DATA EXTRACTION; DENMARK; DRUG USE; EDUCATION; FIRST TRIMESTER PREGNANCY; MATERNAL AGE; PRENATAL DRUG EXPOSURE; PRESCRIPTION; PRIORITY JOURNAL; PROPENSITY SCORE; REGISTER; RISK ASSESSMENT; SENSITIVITY ANALYSIS; SMOKING;

ABNORMALITIES, DRUG-INDUCED; ADULT; CENTRAL NERVOUS SYSTEM STIMULANTS; COHORT STUDIES; DENMARK; FEMALE; HUMANS; METHYLPHENIDATE; PREGNANCY; PREGNANCY TRIMESTER, FIRST; REGISTRIES; RISK; YOUNG ADULT;

EID: 84893072507     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.13m08708     Document Type: Article

References (30)

1. Dideriksen D, Pottegard A, Hallas J, et al. First trimester in utero exposure to methylphenidate. Basic Clin Pharmacol Toxicol. 2013;112(2):73-76. doi:10.1/bcpt.12034 PubMed
2. Bolea-Alamanac BM, Green A, Verma G, et al. Methylphenidate use in pregnancy and lactation, a systematic review of evidence [published online ahead of print April 18, 2013]. Br J Clin Pharmacol. doi:10.1/bcp.12138 PubMed
3. Cantwell DP. Hyperactive children have grown up: what have we learned about what happens to them? Arch Gen Psychiatry. 1985;42(10):1026-1028. doi:10.101/archpsyc.1985.01790301013 PubMed
4. de Zwaan M, Gruss B, Müller A, et al. The estimated prevalence and correlates of adult ADHD in a German community sample. Eur Arch Psychiatry Clin Neurosci. 2012;262(1):79-86. doi:10.107/s0406-01-021-9 PubMed
5. Fayyad J, De Graaf R, Kessler RC, et al. Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder. Br J Psychiatry. 2007;190(5):402-409. doi:10.192/bjp.bp.106.034389 PubMed
6. Concerta XL drug labeling. US Food and Drug Administration Drugs @ FDA Web site. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm? fuseaction=Search.Set-Current-Drug&ApplNo=021121&DrugName= CONCERTA&ActiveIngred=METHYLPHENIDATE%20HYDROCHLORIDE&SponsorApplicant= JANSSEN%20PHARMS&ProductMktStatus=1&goto=Search.DrugDetails Accessed June 30, 2013.
7. Concerta XL Summary of Product Characteristics. Medicines and Healthcare Products Regulatory Agency Web site. http://www.mhra.gov.uk. Accessed June 30, 2013.
8. Greenhill LL, Pliszka S, Dulcan MK, et al; American Academy of Child and Adolescent Psychiatry. Practice parameter for the use of stimulant medications in the treatment of children, adolescents, and adults. J Am Acad Child Adolesc Psychiatry. 2002;41(2, suppl):26S-49S. doi:10.1097/04583-20210-03 PubMed
9. Attention deficit hyperactivity disorder. Clinical guidelines CG72. September 2008. National Institute for Health and Clinical Excellence Web site. http://guidance.nice.org.uk/CG72. Accessed June 21, 2013.
10. Pottegard A, Bjerregaard BK, Glintborg D, et al. The use of medication against attention deficit hyperactivity disorder in Denmark: a drug use study from a national perspective. Eur J Clin Pharmacol. 2012;68(10):1443-1450. doi:10.107/s028-012-1265-y PubMed
11. Lynge E, Sandegaard JL, Rebolj M. The Danish National Patient Register. Scand J Public Health. 2011;39(suppl):30-33. doi:10.17/140349481401482 PubMed
12. Knudsen LB, Olsen J. The Danish Medical Birth Registry. Dan Med Bull. 1998;45(3):320-323. PubMed
13. Kildemoes HW, Sørensen HT, Hallas J. The Danish National Prescription Registry. Scand J Public Health. 2011;39(suppl):38-41. doi:10.17/1403494810394717 PubMed
14. WHO Collaborating Centre for Drug Statistics Methodology. Guidelines for ATC Classification and DDD Assignment 2013. Oslo, Norway: World Health Organization; 2012.
15. Pedersen CB. The Danish Civil Registration System. Scand J Public Health. 2011;39(suppl):22-25. doi:10.17/1403494810387965 PubMed
16. Baadsgaard M, Quitzau J. Danish registers on personal income and transfer payments. Scand J Public Health. 2011;39(suppl):103-105. doi:10.17/ 140349481405098 PubMed
17. Jensen VM, Rasmussen AW. Danish Education Registers. Scand J Public Health. 2011;39(suppl):91-94. doi:10.17/1403494810394715 PubMed
18. Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 9th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2011.
19. Schardein JL. Chemically Induced Birth Defects. 3rd ed. New York, NY: Marcel Dekker Inc; 2000. doi:10.3109/978020390904
20. Glynn RJ, Schneeweiss S, Stürmer T. Indications for propensity scores and review of their use in pharmacoepidemiology. Basic Clin Pharmacol Toxicol. 2006;98(3):253-259. doi:10.1/j.1742-7843.206.pto293.x PubMed
21. Rassen JA, Shelat AA, Myers J, et al. One-to-many propensity score matching in cohort studies. Pharmacoepidemiol Drug Saf. 2012;21 (suppl 2):69-80. doi:10.102/pds.3263 PubMed
22. EUROCAT Guide 1.3 and reference documents. 2005. European Surveillance of Congenital Anomalies Web site. http://www.eurocatnetwork. eu. Accessed November 4, 2013.
23. Methylphenidate. Drugs and pregnancy [in Swedish]. Janusinfo Web site. http://www.janusinfo.se. Accessed October 15, 2013.
24. Wajnberg R, Diav-Citrin O, Shechtman S, et al. Pregnancy outcome after in-utero exposure to methylphenidate: a prospective comparative cohort study. Reprod Toxicol. 2011;13:255-268.
25. Heinonen OP, Slone D, Shapiro S. Birth Defects and Drugs in Pregnancy. Littleton, MA: Publishing Sciences Group. 1977:346-347.
26. Concerta. Pro.medicin.dk Web site. http://www.pro.medicin.dk. Accessed June 30, 2013.
27. Guideline on risk assessment of medical products on human reproduction and lactation: from data to labeling. EMEA/CHMP/203927/2005. European Medicines Agency Web site. http://www.ema.europa.eu. Accessed June 30, 2013.
28. Kristensen J, Langhoff-Roos J, Skovgaard LT, et al. Validation of the Danish Birth Registration. J Clin Epidemiol. 1996;49:893-897. PubMed
29. Larsen H, Nielsen GL, Bendsen J, et al. Predictive value and completeness of the registration of congenital abnormalities in three Danish populationbased registries. Scand J Public Health. 2003;31(1):12-16. doi:10.1080/ 14034940210134194 PubMed
30. Koren G. The effect of ascertainment bias in evaluating gestational antidepressant exposure. J Popul Ther Clin Pharmacol. 2011;18:e174-e175. PubMed