Rituximab for the treatment of refractory simultaneous anti-glomerular basement membrane (anti-GBM) and membranous nephropathy

Clinical Kidney Journal

Volumn 7, Issue 1, 2014, Pages 53-56

  Bandak, Ghassan ^a   Jones, Bruce A ^a   Li, Jian ^a   Yee, Jerry ^a   Umanath, Kausik ^a  

^a HENRY FORD HOSPITAL   (United States)

Author keywords

anti CD 20; anti GBM disease; Goodpasture syndrome; membranous nephropathy, rituximab

Indexed keywords

CHLORIDE; CREATININE; CYCLOPHOSPHAMIDE; GLOMERULUS BASEMENT MEMBRANE ANTIBODY; GLUCOSE; HEMOGLOBIN; LISINOPRIL; METHYLPREDNISOLONE; POTASSIUM; PREDNISONE; RITUXIMAB; SODIUM;

ADULT; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CASE REPORT; CAUCASIAN; CHLORIDE BLOOD LEVEL; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DETERIORATION; DRUG DOSE REDUCTION; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; ELECTRON MICROSCOPY; ERYTHROCYTE SEDIMENTATION RATE; GLOMERULONEPHRITIS; GLOMERULUS BASEMENT MEMBRANE; GLUCOSE BLOOD LEVEL; HEMATOCRIT; HEMATURIA; HEMODIALYSIS; HEMOGLOBIN BLOOD LEVEL; HEMOPTYSIS; HOSPITAL READMISSION; HOSPITALIZATION; HUMAN; HUMAN TISSUE; HUMORAL IMMUNE DEFICIENCY; KIDNEY BIOPSY; KIDNEY FUNCTION; LEUKOCYTE COUNT; MAINTENANCE THERAPY; MALE; MAXIMUM PERMISSIBLE DOSE; MEMBRANOUS GLOMERULONEPHRITIS; PHYSICAL EXAMINATION; PLASMAPHERESIS; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; REMISSION; SINGLE DRUG DOSE; SMOKING; SODIUM BLOOD LEVEL; THROMBOCYTE COUNT; TREATMENT RESPONSE; URINE SEDIMENT; YOUNG ADULT;

EID: 84893069139     PISSN: 20488505     EISSN: 20488513     Source Type: Journal    
DOI: 10.1093/ckj/sft152     Document Type: Article

References (19)

1. Stanton MC, Tange JD. Goodpasture syndrome (pulmonary haemorrhage associated with glomerulonephritis). Australas Ann Med 1958; 7: 132-144
2. Kluth DC, Rees AJ. Anti-glomerular basement membrane disease. J Am Soc Nephrol 1999; 10: 2446-2453
3. Cui Z, Zhao MH. Advances in human antiglomerular basement membrane disease. Nat Rev Nephrol 2011; 7: 697-705
4. Johnson JP, Moore J Jr, Austin HA 3rd et al. Therapy of antiglomerular basement membrane antibody disease: analysis of prognostic significance of clinical, pathologic and treatment factors. Medicine (Baltimore) 1985; 64: 219-227
5. Reff ME, Carner K, Chambers KS et al. Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood 1994; 83: 435-445
6. Chen Y, Schieppati A, Cai G et al. Immunosuppression for membranous nephropathy: a systematic review and metaanalysis of 36 clinical trials. Clin J Am Soc Nephrol 2013; 8: 787-796
7. Basford AW, Lewis J, Dwyer JP et al. Membranous nephropathy with crescents. J AmSoc Nephrol. 2011; 22: 1804-1808
8. Beck LH Jr, Bonegio RG, Lambeau G et al. M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 2009; 361: 11-21
9. Ronco P, Debiec H. Antigen identification in membranous nephropathy moves toward targeted monitoring and new therapy. J Am Soc Nephrol 2010; 21: 564-569
10. Debiec H, Ronco P. PLA2R autoantibodies and PLA2R glomerular deposits in membranous nephropathy. N Engl J Med 2011; 364: 689-690
11. Sklar J, Cleary ML, Thielemans K et al. Biclonal B-cell lymphoma. N Engl J Med 1984; 311: 20-27
12. Bomback AS, Derebail VK, McGregor JG et al. Rituximab therapy for membranous nephropathy: a systematic review. Clin J Am Soc Nephrol 2009; 4: 734-744
13. Ruggenenti P, Cravedi P, Chianca A et al. Rituximab in idiopathic membranous nephropathy. J Am Soc Nephrol 2012; 23: 1416-1425
14. Remuzzi G, Chiurchiu C, Abbate M et al. Rituximab for idiopathic membranous nephropathy. Lancet 2002; 360: 923-924
15. Wechsler E, Yang T, Jordan SC et al. Anti-glomerular basement membrane disease in an HIV-infected patient. Nat Clin Pract Nephrol 2008; 4: 167-171
16. Sauter M, Schmid H, Anders HJ et al. Loss of a renal graft due to recurrence of anti-GBM disease despite rituximab therapy. Clin Transplant 2009; 23: 132-136
17. Arzoo K, Sadeghi S, Liebman HA. Treatment of refractory antibody mediated autoimmune disorders with an anti-CD20 monoclonal antibody (rituximab). Ann Rheum Dis 2002; 61: 922-924
18. Syeda UA, Singer NG, Magrey M. Anti-glomerular basement membrane antibody disease treated with rituximab: a case based review. Semin Arthritis Rheum 2013; 42: 567-572
19. Shah Y, Mohiuddin A, Sluman C et al. Rituximab in anti-glomerular basement membrane disease. QJM 2012; 105: 195-197