Sample size in orthodontic randomized controlled trials: Are numbers justified?

European Journal of Orthodontics

Volumn 36, Issue 1, 2014, Pages 67-73

  Koletsi, Despina ^a   Pandis, Nikolaos ^b   Fleming, Padhraig S ^c  

^a UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY OF BERN   (Switzerland)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; HUMAN; METHODOLOGY; ORTHODONTICS; PUBLICATION; PUBLISHING; RANDOMIZED CONTROLLED TRIAL (TOPIC); SAMPLE SIZE;

HUMANS; ORTHODONTICS; PERIODICALS AS TOPIC; PUBLISHING; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH DESIGN; SAMPLE SIZE;

EID: 84893045626     PISSN: 01415387     EISSN: 14602210     Source Type: Journal    
DOI: 10.1093/ejo/cjt005     Document Type: Article

References (18)

1. Altman D G 1980 Statistics and ethics in medical research: III How large a sample? British Medical Journal 281: 1336-1338
2. Ayeni O, Dickson L, Ignacy T A, Thoma A 2012 A systematic review of power and sample size reporting in randomized controlled trials within plastic surgery. Plastic and Reconstructive Surgery 130: e78-e86
3. Bacchetti P 2002 Peer review of statistics in medical research: the other problem. British Medical Journal 324: 1271-1273
4. Benson P 2011 Registration of clinical trials. Journal of Orthodontics 38: 75-76
5. Charles P, Giraudeau B, Dechartres A, Baron G, Ravaud P 2009 Reporting of sample size calculation in randomised controlled trials: review. British Medical Journal 338: b1732
6. Freiman J A, Chalmers T C, Smith H Jr, Kuebler R R 1978 The importance of beta, the type II error and sample size in the design and interpretation of the randomized control trial. Survey of 71 "negative" trials. The New England Journal of Medicine 299: 690-694
7. Gravel J, Opatrny L, Shapiro S 2007 The intention-to-treat approach in randomized controlled trials: are authors saying what they do and doing what they say? Clinical Trials 4: 350-356
8. Halpern S D, Karlawish J H, Berlin J A 2002 The continuing unethical conduct of underpowered clinical trials. The Journal of the American Medical Association 288: 358-362
9. Hollis S, Campbell F 1999 What is meant by intention to treat analysis? Survey of published randomised controlled trials. British Medical Journal 319: 670-674
10. Kerry S M, Bland J M 1998 Analysis of a trial randomised in clusters. British Medical Journal 316: 54
11. Kruse R L, Alper B S, Reust C, Stevermer J J, Shannon S, Williams R H 2002 Intention-to-treat analysis: who is in? Who is out? The Journal of Family Practice 51: 969-971
12. Machin D, Campbell M, Fayers P, Pinol A 1997 Sample Size Tables for Clinical Studies, 2nd edn. Blackwell Science
13. Oxford Meinert C L, Tonascia S, Higgins K 1984 Content of reports on clinical trials: a critical review. Controlled Clinical Trials 5: 328-347
14. Schulz K F, Altman D G, Moher D; CONSORT Group. 2010a CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. PLoS Medicine 7: e1000251
15. Schulz K F, Altman D G, Moher D; CONSORT Group. 2010b CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. Journal of Clinical Epidemiology 63: 834-840
16. Schulz K F, Grimes D A 2005 Sample size calculations in randomised trials: mandatory and mystical. Lancet 365: 1348-1353
17. Vickers A J 2003 Underpowering in randomized trials reporting a sample size calculation. Journal of Clinical Epidemiology 56: 717-720
18. Wooding W M 1994 Planning Pharmaceutical Clinical Trials. John Wiley and Sons, Chichester