Pharmacokinetics and safety of Migalastat HCl and effects on agalsidase activity in healthy volunteers

Clinical Pharmacology in Drug Development

Volumn 2, Issue 2, 2013, Pages 120-132

  Johnson, Franklin K ^a   Mudd, Paul N ^b   Bragat, Alexander ^c   Adera, Mathews ^c   Boudes, Pol ^c  

^a Amicus Therapeutics   (United States)

^b GLAXOSMITHKLINE   (United States)

^c Clinical Development   (United States)

Author keywords

Enzyme replacement therapy; Fabry disease; Lysosomal storage disorders; Pharmacokinetics; Pharmacological chaperone

Indexed keywords

ALPHA GALACTOSIDASE; MIGALASTAT; PLACEBO;

ADULT; AREA UNDER THE CURVE; ARTICLE; CARDIOTOXICITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG EXCRETION; DRUG SAFETY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; QT PROLONGATION; SINGLE DRUG DOSE; STEADY STATE; URINARY EXCRETION; VOLUNTEER;

EID: 84893045608     PISSN: 2160763X     EISSN: 21607648     Source Type: Journal    
DOI: 10.1002/cpdd.1     Document Type: Article

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