Protection from cyclophosphamide-induced ovarian damage with bone marrow-derived mesenchymal stem cells during puberty

Gynecological Endocrinology

Volumn 30, Issue 2, 2014, Pages 135-140

  Kilic, Sevtap ^a   Pinarli, Ferda ^a   Ozogul, Candan ^b   Tasdemir, Nicel ^c   Naz Sarac, Gulce ^b   Delibasi, Tuncay ^a  

^a Laboratory Animal and Stem Cell Research Center   (Turkey)

^b GAZI UNIVERSITY   (Turkey)

^c NAMIK KEMAL UNIVERSITY   (Turkey)

Author keywords

Apoptosis; Chemotherapy; Childhood cancer; Mesenchymal stem cell; Puberty

Indexed keywords

CASPASE 9; CYCLOPHOSPHAMIDE; DNA; GONADORELIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; FEMALE; GERM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STEM CELL; NICK END LABELING; NONHUMAN; OVARY DISEASE; OVARY FOLLICLE CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTECTION; PUBERTY; RAT; SRY GENE; THERAPY EFFECT; Y CHROMOSOME;

ANIMALS; APOPTOSIS; CYCLOPHOSPHAMIDE; DNA FRAGMENTATION; FEMALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; OVARIAN FOLLICLE; OVARY; PRIMARY OVARIAN INSUFFICIENCY; RATS; RATS, WISTAR;

EID: 84893044553     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.3109/09513590.2013.860127     Document Type: Article

References (40)

1. Schilsky RL, Lewis BJ, Sherins RJ, & Young RC. Gonadal dysfunction in patients receiving chemotherapy for cancer. Ann Intern Med 1980;93:109-14
2. Chapman RM, Sutcliffe SB, Malpas JS. Cytotoxic-induced ovarian failure in women with hodgkin's disease. I. Hormone function. JAMA 1979;242:1877-81
3. Ries Lag MD, Krapcho M, Stinchcomb DG, et al. Seer cancer statistics review. National Cancer Institute 2008
4. Hudson M. Reproductive outcomes for survivors of childhood cancer. Obstet Gynecol 2010;116:1171-83
5. Mackie EJ, Radford M, Shalet SM. Gonadal function following chemotherapy for childhood Hodgkin's disease. Med Pediatr Oncol 1996;27:74-8
6. Clark ST, Radford JA, Crowther D, et al. Gonadal function following chemotherapy for Hodgkin's disease: A comparative study of mvpp and a seven-drug hybrid regimen. J Clin Oncol 1995;13:134-9
7. Byrne J. Infertility and premature menopause in childhood cancer survivors. Med Pediatr Oncol 1999;33:24-8
8. Sklar C. Reproductive physiology and treatment-related loss of sex hormone production. Med Pediatr Oncol 1999;33:2-8
9. Eliopoulos N, Zhao J, Forner K, et al. Erythropoietin gene-enhanced marrow mesenchymal stromal cells decrease cisplatin-induced kidney injury and improve survival of allogeneic mice. Mol Ther 2011;19:2072-83
10. Diez Villanueva P, Sanz-Ruiz R, Nunez Garcia A, et al. Functional multipotency of stem cells: What do we need from them in the heart? Stem Cells Int 2012;2012:817364
11. Seiden MV, Spitzer TR, Mcafee S, Fuller AF. Successful pregnancy after high-dose cyclophosphamide, carboplatinum, and taxol with peripheral blood stem cell transplant in a young woman with ovarian carcinoma. Gynecol Oncol 2001;83:412-14
12. Sanchez PL, Villa A, Sanz R, et al. Present and future of stem cells for cardiovascular therapy. Ann Med 2007;39:412-27
13. Glode LM, Robinson J, Gould SF. Protection from cyclophosphamide-induced testicular damage with an analogue of gonadotropinreleasing hormone. Lancet 1981;1:1132-4
14. Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418:41-9
15. Bryja JK. A fast sex identification in wild mammals using pcramplification of the sry gene. Folia Zool 2003;52:269-74
16. Ise H, Nikaido T, Negishi N, et al. Effective hepatocyte transplantation using rat hepatocytes with low asialoglycoprotein receptor expression. Am J Pathol 2004;165:501-10
17. Chemaitilly W, Mertens AC, Mitby P, et al. Acute ovarian failure in the childhood cancer survivor study. J Clin Endocrinol Metab 2006; 91:1723-8
18. Wallace WH, Anderson RA, Irvine DS. Fertility preservation for young patients with cancer: Who is at risk and what can be offered? Lancet Oncol 2005;6:209-18
19. Sklar C. Maintenance of ovarian function and risk of premature menopause related to cancer treatment. J Natl Cancer Inst Monogr 2005;(34):25-7
20. Oktay K, Turkcuoglu I, Rodriguez-Wallberg KA. Four spontaneous pregnancies and three live births following subcutaneous transplantation of frozen banked ovarian tissue: What is the explanatioñ Fertil Steril 2011;95:804.e7-10
21. Sonmezer M, Oktay K. Orthotopic and heterotopic ovarian tissue transplantation. Best Pract Res Clin Obstet Gynaecol 2010;24: 113-26
22. Johnson J, Canning J, Kaneko T, et al. Germline stem cells and follicular renewal in the postnatal mammalian ovary. Nature 2004; 428:145-50
23. Flaws JA, Abbud R, Mann RJ, et al. Chronically elevated luteinizing hormone depletes primordial follicles in the mouse ovary. Biol Reprod 1997;57:1233-7
24. Blumenfeld Z, Dann E, Avivi I, et al. M. Fertility after treatment for hodgkin's disease. Ann Oncol 2002;13:138-47
25. Ataya K, Rao LV, Lawrence E, Kimmel R. Luteinizing hormonereleasing hormone agonist inhibits cyclophosphamide-induced ovarian follicular depletion in rhesus monkeys. Biol Reprod 1995;52: 365-72
26. Badawy A, Elnashar A, El-ashry M, Shahat M. Gonadotropinreleasing hormone agonists for prevention of chemotherapy-induced ovarian damage: Prospective randomized study. Fertil Steril 2009; 91:694-7
27. Pereyra Pacheco B, Mendez Ribas JM, Milone G, et al. Use of gnrh analogs for functional protection of the ovary and preservation of fertility during cancer treatment in adolescents: A preliminary report. Gynecol Oncol 2001;81:391-7
28. Sverrisdottir A, Nystedt M, Johansson H, Fornander T. Adjuvant goserelin and ovarian preservation in chemotherapy treated patients with early breast cancer: Results from a randomized trial. Breast Cancer Res Treat 2009;117:561-7
29. Ben-Aharon I, Gafter-Gvili A, Leibovici L, Stemmer SM. Pharmacological interventions for fertility preservation during chemotherapy: A systematic review and meta-analysis. Breast Cancer Res Treat 2010;122:803-11
30. Del Mastro L, Catzeddu T, Boni L, et al. Prevention of chemotherapy-induced menopause by temporary ovarian suppression with goserelin in young, early breast cancer patients. Ann Oncol 2006;17: 74-8
31. Demeestere I, Brice P, Peccatori FA, et al. Gonadotropin-releasing hormone agonist for the prevention of chemotherapy-induced ovarian failure in patients with lymphoma: 1-year follow-up of a prospective randomized trial. J Clin Oncol 2013;31:903-9
32. Toft E., Becedas L, Soderstrom M, et al. Glutathione transferase isoenzyme patterns in the rat ovary. Chem Biol Interact 1997;108: 79-93
33. Rahilly M, Carder PJ, Al Nafussi A, Harrison DJ. Distribution of glutathione s-transferase isoenzymes in human ovary. J Reprod Fertil 1991;93:303-11
34. Gamcsik MP, Dolan ME, Andersson BS, Murray D. Mechanisms of resistance to the toxicity of cyclophosphamide. Curr Pharm Des 1999;5:587-605
35. Oktay K, Sonmezer M, Oktem O, et al. Absence of conclusive evidence for the safety and efficacy of gonadotropin-releasing hormone analogue treatment in protecting against chemotherapyinduced gonadal injury. Oncologist 2007;12:1055-66
36. Guth PH, Paulsen G. Aspirin-induced gastric injury in the rat: Histologic changes and sucralfate cytoprotection. Proc Soc Exp Biol Med 1987;184:423-8
37. Li HC, Stoicov C, Rogers AB, Houghton J. Stem cells and cancer: Evidence for bone marrow stem cells in epithelial cancers. World J Gastroenterol 2006;12:363-71
38. Lee HJ, Selesniemi K, Niikura Y, et al. Bone marrow transplantation generates immature oocytes and rescues long-term fertility in a preclinical mouse model of chemotherapy-induced premature ovarian failure. J Clin Oncol 2007;25:3198-204
39. Takehara Y, Yabuuchi A, Ezoe K, et al. The restorative effects of adipose-derived mesenchymal stem cells on damaged ovarian function. Lab Invest 2013;93:181-93
40. Fu X, He Y, Xie C, Liu W. Bone marrow mesenchymal stem cell transplantation improves ovarian function and structure in rats with chemotherapy-induced ovarian damage. Cytotherapy 2008;10: 353-63