CMR-verified interstitial myocardial fibrosis as a marker of subclinical cardiac involvement in LMNA mutation carriers

JACC: Cardiovascular Imaging

Volumn 6, Issue 1, 2013, Pages

  Fontana, Marianna ^a   Barison, Andrea ^a   Botto, Nicoletta ^a   Panchetti, Luca ^a   Ricci, Giulia ^a   Milanesi, Matteo ^a   Poletti, Roberta ^a   Positano, Vincenzo ^a   Siciliano, Gabriele ^a   Passino, Claudio ^a   Lombardi, Massimo ^a   Emdin, Michele ^a   Masci, Pier Giorgio ^a  

^a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE[_DLNK ENDOGENOUS COMPOUND]; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CATECHOLAMINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GADODIAMIDE; GADOLINIUM; LAMIN A; UNCLASSIFIED DRUG;

ALDOSTERONE BLOOD LEVEL; ATRIOVENTRICULAR BLOCK; ATRIOVENTRICULAR CONDUCTION; BLOOD SAMPLING; CARDIOPULMONARY EXERCISE TEST; CARDIOVASCULAR MAGNETIC RESONANCE; CATECHOLAMINE BLOOD LEVEL; ELECTROCARDIOGRAPHY MONITORING; FIRST DEGREE ATRIOVENTRICULAR BLOCK; GENE EXPRESSION; GENE MUTATION; GENOTYPE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE FIBROSIS; HEART VENTRICLE SIZE; HEMATOCRIT; HOLTER MONITORING; HUMAN; INCIDENCE; LETTER; PATIENT REFERRAL; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 84893042853     PISSN: 1936878X     EISSN: 18767591     Source Type: Journal    
DOI: 10.1016/j.jcmg.2012.06.013     Document Type: Letter

References (4)

1. J.H. Van Berlo, W.G. Voogt, A.J. Kooi Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations J Mol Med 83 2005 79 83
2. J.P. Van Tintelen, R.A. Tio, W.S. Kerstjens-Frederikse Severe myocardial fibrosis caused by a deletion of the 5′ end of lamin A/C gene J Am Coll Cardiol 49 2007 2430 2439
3. M. Jerosch-Herold, D.C. Sheridan, J.D. Kushner Cardiac magnetic resonance imaging of myocardial contrast uptake and blood flow in patients affected with idiopathic or familial dilated cardiomyopathy Am J Physiol Heart Circ Physiol 295 2008 H1234 H1242
4. S.V. Raman, E.A. Sparks, P.M. Baker Mid-myocardial fibrosis by cardiac magnetic resonance in patients with lamin A/C cardiomyopathy J Cardiovasc Magn Reson 9 2007 907 913