Synthesis, characterization and in vitro anti-neoplastic activity of gypsogenin derivatives

Bioorganic Chemistry

Volumn 53, Issue , 2014, Pages 15-23

  Emirdaǧ Öztürk, Safiye ^a   Babahan, Ilknur ^b   Özmen, Ali ^b  

^a EGE UNIVERSITY   (Turkey)

^b ADNAN MENDERES UNIVERSITY   (Turkey)

Author keywords

Antiproliferative; Gypsogenin; Leukemia; Thiosemicarbazone; Transition metal complex; vic Dioxime

Indexed keywords

(3BETA) 3 HYDROXY 23 [[[[(1,2) N HYDROXY 2 (HYDROXYIMINO)ETHANIMIDOYL]AMINO]CARBONOTHIOYL]HYDRAZONO]OLEAN 12 EN 28 OIC ACID; 23 [(AMINOCARBONOTHIOYL)HYDRAZONO]HYDROXOLEAN 12 EN 28 OIC ACID; 3 HYDROXY 23 OXOOLEAN 12 EN 28 OIC ACID; ANTINEOPLASTIC AGENT; PACLITAXEL; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG; COBALT; COORDINATION COMPOUND; COPPER; SAPONIN; THIOSEMICARBAZONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG SYNTHESIS; GYPSOPHILA ARROSTII; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INFRARED SPECTROSCOPY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINAL PLANT; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; APOPTOSIS; CHEMISTRY; CONFORMATION; DRUG EFFECTS; HL 60 CELL LINE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL PROLIFERATION; COBALT; COORDINATION COMPLEXES; COPPER; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; SAPONINS; THIOSEMICARBAZONES;

EID: 84893038963     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2013.12.001     Document Type: Article

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