메뉴 건너뛰기




Volumn 38, Issue 2, 2014, Pages 257-264

Use of p40 and p63 immunohistochemistry and human papillomavirus testing as ancillary tools for the recognition of head and neck sarcomatoid carcinoma and its distinction from benign and malignant mesenchymal processes

Author keywords

carcinosarcoma; head and neck squamous cell carcinoma; human papillomavirus; sarcomatoid carcinoma; spindle cell carcinoma

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; ISOPROTEIN; KERATIN; TP63 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN; VIRUS DNA;

EID: 84893024884     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0000000000000119     Document Type: Article
Times cited : (77)

References (45)
  • 1
    • 0027291679 scopus 로고
    • Sarcomatoid neoplasms of the respiratory tract
    • Nappi O, Wick MR. Sarcomatoid neoplasms of the respiratory tract. Semin Diagn Pathol. 1993;10:137-147.
    • (1993) Semin Diagn Pathol. , vol.10 , pp. 137-147
    • Nappi, O.1    Wick, M.R.2
  • 2
    • 0034268587 scopus 로고    scopus 로고
    • Sarcomatoid carcinomas of the upper aerodigestive tracts
    • Batsakis JG, Suarez P. Sarcomatoid carcinomas of the upper aerodigestive tracts. Adv Anat Pathol. 2000;7:282-293.
    • (2000) Adv Anat Pathol. , vol.7 , pp. 282-293
    • Batsakis, J.G.1    Suarez, P.2
  • 4
    • 0036324562 scopus 로고    scopus 로고
    • Immunohistochem-ical p53 expression patterns in sarcomatoid carcinomas of the upper respiratory tract
    • Ansari-Lari MA, Hoque MO, Califano J, et al. Immunohistochem-ical p53 expression patterns in sarcomatoid carcinomas of the upper respiratory tract. Am J Surg Pathol. 2002;26:1024-1031.
    • (2002) Am J Surg Pathol. , vol.26 , pp. 1024-1031
    • Ansari-Lari, M.A.1    Hoque, M.O.2    Califano, J.3
  • 5
    • 84915129869 scopus 로고
    • Pseudosarcoma (polypoid sarcoma-like masses) associated with squamous-cell carcinoma of the mouth, fauces, and larynx
    • Lane N. Pseudosarcoma (polypoid sarcoma-like masses) associated with squamous-cell carcinoma of the mouth, fauces, and larynx. Cancer. 1957;10:19-41.
    • (1957) Cancer. , vol.10 , pp. 19-41
    • Lane, N.1
  • 6
    • 0036158664 scopus 로고    scopus 로고
    • Spindle cell (sarcomatoid) carcinomas of the larynx: A clinicopathologic study of 187 cases
    • Thompson LD, Wieneke JA, Miettinen M, et al. Spindle cell (sarcomatoid) carcinomas of the larynx: a clinicopathologic study of 187 cases. Am J Surg Pathol. 2002;26:153-170.
    • (2002) Am J Surg Pathol. , vol.26 , pp. 153-170
    • Thompson, L.D.1    Wieneke, J.A.2    Miettinen, M.3
  • 7
    • 0023025307 scopus 로고
    • Spindle-cell carcinoma of the upper aerodigestive tract mucosa. An immunohistologic and ultrastructural study of 18 biphasic tumors and comparison with seven monophasic spindle-cell tumors
    • Zarbo RJ, Crissman JD, Venkat H, et al. Spindle-cell carcinoma of the upper aerodigestive tract mucosa. An immunohistologic and ultrastructural study of 18 biphasic tumors and comparison with seven monophasic spindle-cell tumors. Am J Surg Pathol. 1986;10:741-753.
    • (1986) Am J Surg Pathol. , vol.10 , pp. 741-753
    • Zarbo, R.J.1    Crissman, J.D.2    Venkat, H.3
  • 8
    • 0031007646 scopus 로고    scopus 로고
    • Spindle cell carcinoma of the larynx: Review of 26 cases including DNA content and immunohistochem-istry
    • Lewis JE, Olsen KD, Sebo TJ. Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochem-istry. Hum Pathol. 1997;28:664-673.
    • (1997) Hum Pathol. , vol.28 , pp. 664-673
    • Lewis, J.E.1    Olsen, K.D.2    Sebo, T.J.3
  • 9
    • 27144532355 scopus 로고    scopus 로고
    • Alternative epithelial markers in sarcomatoid carcinomas of the head and neck, lung, and bladder-p63, MOC-31, and TTF-1
    • Lewis JS, Ritter JH, El-Mofty S. Alternative epithelial markers in sarcomatoid carcinomas of the head and neck, lung, and bladder-p63, MOC-31, and TTF-1. Mod Pathol. 2005;18:1471-1481.
    • (2005) Mod Pathol. , vol.18 , pp. 1471-1481
    • Lewis, J.S.1    Ritter, J.H.2    El-Mofty, S.3
  • 10
    • 0023183563 scopus 로고
    • Cytokeratin expression in smooth muscle and smooth muscle tumours
    • Brown DC, Theaker JM, Banks PM, et al. Cytokeratin expression in smooth muscle and smooth muscle tumours. Histopathology. 1987;11:477-486.
    • (1987) Histopathology. , vol.11 , pp. 477-486
    • Brown, D.C.1    Theaker, J.M.2    Banks, P.M.3
  • 11
    • 0025219879 scopus 로고
    • Cytokeratin expression in epithelioid vascular neoplasms
    • Gray MH, Rosenberg AE, Dickersin GR, et al. Cytokeratin expression in epithelioid vascular neoplasms. Hum Pathol. 1990;21:212-217.
    • (1990) Hum Pathol. , vol.21 , pp. 212-217
    • Gray, M.H.1    Rosenberg, A.E.2    Dickersin, G.R.3
  • 12
    • 0025919727 scopus 로고
    • Epithelioid angiosarcoma of deep soft tissue: A distinctive tumor readily mistaken for an epithelial neoplasm
    • Fletcher CD, Beham A, Bekir S, et al. Epithelioid angiosarcoma of deep soft tissue: a distinctive tumor readily mistaken for an epithelial neoplasm. Am J Surg Pathol. 1991;15:915-924.
    • (1991) Am J Surg Pathol. , vol.15 , pp. 915-924
    • Fletcher, C.D.1    Beham, A.2    Bekir, S.3
  • 13
    • 0021672227 scopus 로고
    • Keratin proteins and carcinoembryonic antigen in synovial sarcomas: An immuno-histochemical study of 24 cases
    • Corson JM, Weiss LM, Banks-Schlegel SP, et al. Keratin proteins and carcinoembryonic antigen in synovial sarcomas: an immuno-histochemical study of 24 cases. Hum Pathol. 1984;15:615-621.
    • (1984) Hum Pathol. , vol.15 , pp. 615-621
    • Corson, J.M.1    Weiss, L.M.2    Banks-Schlegel, S.P.3
  • 14
    • 0031904932 scopus 로고    scopus 로고
    • The role of immunohistochemistry in the differential diagnosis of soft-tissue tumors
    • Muro-Cacho CA. The role of immunohistochemistry in the differential diagnosis of soft-tissue tumors. Cancer Control. 1998;5: 53-63.
    • (1998) Cancer Control. , vol.5 , pp. 53-63
    • Muro-Cacho, C.A.1
  • 15
    • 0034089175 scopus 로고    scopus 로고
    • Cytokeratin immunor-eactivity in Ewing's sarcoma: Prevalence in 50 cases confirmed by molecular diagnostic studies
    • Gu M, Antonescu CR, Guiter G, et al. Cytokeratin immunor-eactivity in Ewing's sarcoma: prevalence in 50 cases confirmed by molecular diagnostic studies. Am J Surg Pathol. 2000;24:410-416.
    • (2000) Am J Surg Pathol. , vol.24 , pp. 410-416
    • Gu, M.1    Antonescu, C.R.2    Guiter, G.3
  • 16
    • 0024496848 scopus 로고
    • Immunohistochemical spectrum of rhabdo-myosarcoma and rhabdomyosarcoma-like tumors. Expression of cytokeratin and the 68-kD neurofilament protein
    • Miettinen M, Rapola J. Immunohistochemical spectrum of rhabdo-myosarcoma and rhabdomyosarcoma-like tumors. Expression of cytokeratin and the 68-kD neurofilament protein. Am J Surg Pathol. 1989;13:120-132.
    • (1989) Am J Surg Pathol. , vol.13 , pp. 120-132
    • Miettinen, M.1    Rapola, J.2
  • 17
    • 0023896956 scopus 로고
    • Immunoreactivity for cytokeratin and epithelial membrane antigen in leiomyosarcoma
    • Miettinen M. Immunoreactivity for cytokeratin and epithelial membrane antigen in leiomyosarcoma. Arch Pathol Lab Med. 1988;112:637-640.
    • (1988) Arch Pathol Lab Med. , vol.112 , pp. 637-640
    • Miettinen, M.1
  • 18
    • 0037559652 scopus 로고    scopus 로고
    • Immunohistochemistry in the diagnosis of soft tissue tumours
    • Coindre JM. Immunohistochemistry in the diagnosis of soft tissue tumours. Histopathology. 2003;43:1-16.
    • (2003) Histopathology. , vol.43 , pp. 1-16
    • Coindre, J.M.1
  • 19
    • 0030754694 scopus 로고    scopus 로고
    • Immunohistochemical and molecular genetic approaches to soft tissue tumor diagnosis: A primer
    • Hibshoosh H, Lattes R. Immunohistochemical and molecular genetic approaches to soft tissue tumor diagnosis: a primer. Semin Oncol. 1997;24:515-525.
    • (1997) Semin Oncol. , vol.24 , pp. 515-525
    • Hibshoosh, H.1    Lattes, R.2
  • 20
    • 0028801732 scopus 로고
    • Atypical stromal cells in inflammatory nasal polyps: Immunohistochemical and ultrastruc-tural analysis in defining histogenesis
    • Nakayama M, Wenig BM, Heffner DK. Atypical stromal cells in inflammatory nasal polyps: immunohistochemical and ultrastruc-tural analysis in defining histogenesis. Laryngoscope. 1995;105: 127-134.
    • (1995) Laryngoscope. , vol.105 , pp. 127-134
    • Nakayama, M.1    Wenig, B.M.2    Heffner, D.K.3
  • 21
    • 68049122368 scopus 로고    scopus 로고
    • Diagnostic utility of P63 and CD10 in distinguishing cutaneous spindle cell/sarcomatoid squamous cell carcinomas and atypical fibroxanthomas
    • Hall JM, Saenger JS, Fadare O. Diagnostic utility of P63 and CD10 in distinguishing cutaneous spindle cell/sarcomatoid squamous cell carcinomas and atypical fibroxanthomas. Int J Clin Exp Pathol. 2008;1:524-530.
    • (2008) Int J Clin Exp Pathol. , vol.1 , pp. 524-530
    • Hall, J.M.1    Saenger, J.S.2    Fadare, O.3
  • 22
    • 33144460460 scopus 로고    scopus 로고
    • P63 is useful in the diagnosis of mammary metaplastic carcinomas
    • Tse GM, Tan PH, Chaiwun B, et al. p63 is useful in the diagnosis of mammary metaplastic carcinomas. Pathology. 2006;38:16-20.
    • (2006) Pathology. , vol.38 , pp. 16-20
    • Tse, G.M.1    Tan, P.H.2    Chaiwun, B.3
  • 23
    • 0037229491 scopus 로고    scopus 로고
    • P63 expression in sarcomatoid/meta-plastic carcinomas of the breast
    • Reis-Filho JS, Schmitt FC. P63 expression in sarcomatoid/meta-plastic carcinomas of the breast. Histopathology. 2003;42:94-95.
    • (2003) Histopathology. , vol.42 , pp. 94-95
    • Reis-Filho, J.S.1    Schmitt, F.C.2
  • 24
    • 59149084731 scopus 로고    scopus 로고
    • Utility of a comprehensive immunohistochemical panel in the differential diagnosis of spindle cell lesions of the urinary bladder
    • Westfall DE, Folpe AL, Paner GP, et al. Utility of a comprehensive immunohistochemical panel in the differential diagnosis of spindle cell lesions of the urinary bladder. Am J Surg Pathol. 2009;33: 99-105.
    • (2009) Am J Surg Pathol. , vol.33 , pp. 99-105
    • Westfall, D.E.1    Folpe, A.L.2    Paner, G.P.3
  • 25
    • 24144503376 scopus 로고    scopus 로고
    • Sarcomatoid carcinoma of the penis: A clinicopathologic study of 15 cases
    • Velazquez EF, Melamed J, Barreto JE, et al. Sarcomatoid carcinoma of the penis: a clinicopathologic study of 15 cases. Am J Surg Pathol. 2005;29:1152-1158.
    • (2005) Am J Surg Pathol. , vol.29 , pp. 1152-1158
    • Velazquez, E.F.1    Melamed, J.2    Barreto, J.E.3
  • 26
    • 80355126433 scopus 로고    scopus 로고
    • P63 immunohistochemical staining is limited in soft tissue tumors
    • Jo VY, Fletcher CD. p63 immunohistochemical staining is limited in soft tissue tumors. Am J Clin Pathol. 2011;136:762-766.
    • (2011) Am J Clin Pathol. , vol.136 , pp. 762-766
    • Jo, V.Y.1    Fletcher, C.D.2
  • 27
    • 84855286368 scopus 로고    scopus 로고
    • Occasional staining for p63 in malignant vascular tumors: A potential diagnostic pitfall
    • Kallen ME, Nunes Rosado FG, Gonzalez AL, et al. Occasional staining for p63 in malignant vascular tumors: a potential diagnostic pitfall. Pathol Oncol Res. 2011;18:97-100.
    • (2011) Pathol Oncol Res. , vol.18 , pp. 97-100
    • Kallen, M.E.1    Nunes Rosado, F.G.2    Gonzalez, A.L.3
  • 28
    • 77949894769 scopus 로고    scopus 로고
    • P63 in epithelial survival, germ cell surveillance, and neoplasia
    • Crum CP, McKeon FD. P63 in epithelial survival, germ cell surveillance, and neoplasia. Annu Rev Pathol. 2010;5:349-371.
    • (2010) Annu Rev Pathol. , vol.5 , pp. 349-371
    • Crum, C.P.1    McKeon, F.D.2
  • 29
    • 84857794792 scopus 로고    scopus 로고
    • P40 (DeltaNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma
    • Bishop JA, Teruya-Feldstein J, Westra WH, et al. p40 (DeltaNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma. Mod Pathol. 2012;25:405-415.
    • (2012) Mod Pathol. , vol.25 , pp. 405-415
    • Bishop, J.A.1    Teruya-Feldstein, J.2    Westra, W.H.3
  • 30
    • 33749477086 scopus 로고    scopus 로고
    • DeltaNp63 protein expression in uterine cervical and endometrial cancers
    • Lin Z, Liu M, Li Z, et al. DeltaNp63 protein expression in uterine cervical and endometrial cancers. J Cancer Res Clin Oncol. 2006;132:811-816.
    • (2006) J Cancer Res Clin Oncol. , vol.132 , pp. 811-816
    • Lin, Z.1    Liu, M.2    Li, Z.3
  • 31
    • 0034625043 scopus 로고    scopus 로고
    • AIS is an oncogene amplified in squamous cell carcinoma
    • Hibi K, Trink B, Patturajan M, et al. AIS is an oncogene amplified in squamous cell carcinoma. Proc Natl Acad Sci USA. 2000; 97:5462-5467.
    • (2000) Proc Natl Acad Sci USA. , vol.97 , pp. 5462-5467
    • Hibi, K.1    Trink, B.2    Patturajan, M.3
  • 32
    • 79960670179 scopus 로고    scopus 로고
    • Different prevalence of transactivating (TA) p63 and non-TAp63 isoforms in pulmonary adenocarcinomas: A useful diagnostic tool
    • Pelosi G, Sonzogni A, Papotti M, et al. Different prevalence of transactivating (TA) p63 and non-TAp63 isoforms in pulmonary adenocarcinomas: a useful diagnostic tool. Mod Pathol. 2010;23:411A-412A.
    • (2010) Mod Pathol. , vol.23
    • Pelosi, G.1    Sonzogni, A.2    Papotti, M.3
  • 33
    • 79960674310 scopus 로고    scopus 로고
    • Immunohistochemical subtyping of nonsmall cell lung cancer not otherwise specified in fine-needle aspiration cytology: A retrospective study of 103 cases with surgical correlation
    • Righi L, Graziano P, Fornari A, et al. Immunohistochemical subtyping of nonsmall cell lung cancer not otherwise specified in fine-needle aspiration cytology: a retrospective study of 103 cases with surgical correlation. Cancer. 2011;117:3416-3423.
    • (2011) Cancer. , vol.117 , pp. 3416-3423
    • Righi, L.1    Graziano, P.2    Fornari, A.3
  • 34
    • 79251579006 scopus 로고    scopus 로고
    • MiR-205 Expression levels in nonsmall cell lung cancer do not always distinguish adenocarcinomas from squamous cell carcinomas
    • Del Vescovo V, Cantaloni C, Cucino A, et al. miR-205 Expression levels in nonsmall cell lung cancer do not always distinguish adenocarcinomas from squamous cell carcinomas. Am J Surg Pathol. 2011;35:268-275.
    • (2011) Am J Surg Pathol. , vol.35 , pp. 268-275
    • Del Vescovo, V.1    Cantaloni, C.2    Cucino, A.3
  • 35
    • 77954190940 scopus 로고    scopus 로고
    • Human papillomavirus and survival of patients with oropharyngeal cancer
    • Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med. 2010;363:24-35.
    • (2010) N Engl J Med. , vol.363 , pp. 24-35
    • Ang, K.K.1    Harris, J.2    Wheeler, R.3
  • 36
    • 0034600339 scopus 로고    scopus 로고
    • Evidence for a causal association between human papillomavirus and a subset of head and neck cancers
    • Gillison ML, Koch WM, Capone RB, et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst. 2000;92:709-720.
    • (2000) J Natl Cancer Inst. , vol.92 , pp. 709-720
    • Gillison, M.L.1    Koch, W.M.2    Capone, R.B.3
  • 37
    • 77449138742 scopus 로고    scopus 로고
    • Head and neck squamous cell cancer and the human papillomavirus. Summary of a National Cancer Institute State of the Science Meeting November 9-10, 2008, Washington, D.C
    • Adelstein DJ, Ridge JA, Gillison ML, et al. Head and neck squamous cell cancer and the human papillomavirus. summary of a National Cancer Institute State of the Science Meeting, November 9-10, 2008, Washington, D.C. Head Neck. 2009;31:1393-1422.
    • (2009) Head Neck. , vol.31 , pp. 1393-1422
    • Adelstein, D.J.1    Ridge, J.A.2    Gillison, M.L.3
  • 38
    • 84864117690 scopus 로고    scopus 로고
    • P16 Immunohistochemistry as a standalone test for risk stratification in oropharyngeal squamous cell carcinoma
    • Lewis JS Jr. p16 Immunohistochemistry as a standalone test for risk stratification in oropharyngeal squamous cell carcinoma. Head Neck Pathol. 2012;6(suppl 1):S75-S82.
    • (2012) Head Neck Pathol. , vol.6 , Issue.SUPPL. 1
    • Lewis Jr., J.S.1
  • 39
    • 77951457224 scopus 로고    scopus 로고
    • Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience
    • Singhi AD, Westra WH. Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience. Cancer. 2010;116:2166-2173.
    • (2010) Cancer. , vol.116 , pp. 2166-2173
    • Singhi, A.D.1    Westra, W.H.2
  • 40
    • 84885069331 scopus 로고    scopus 로고
    • Metastatic squamous cell carcinoma to the brain: An unrecognized pattern of distant spread in patients with HPV-related head and neck cancer
    • Ruzevick J, Olivi A, Westra WH. Metastatic squamous cell carcinoma to the brain: an unrecognized pattern of distant spread in patients with HPV-related head and neck cancer. J Neurooncol. 2013;112:449-454.
    • (2013) J Neurooncol. , vol.112 , pp. 449-454
    • Ruzevick, J.1    Olivi, A.2    Westra, W.H.3
  • 41
    • 84255191435 scopus 로고    scopus 로고
    • HPV analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma
    • Bishop JA, Ogawa T, Chang X, et al. HPV analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma. Am J Surg Pathol. 2012;36:142-148.
    • (2012) Am J Surg Pathol. , vol.36 , pp. 142-148
    • Bishop, J.A.1    Ogawa, T.2    Chang, X.3
  • 42
    • 80055019747 scopus 로고    scopus 로고
    • Human papillomavirus-related small cell carcinoma of the oropharynx
    • Bishop JA, Westra WH. Human papillomavirus-related small cell carcinoma of the oropharynx. Am J Surg Pathol. 2011;35: 1679-1684.
    • (2011) Am J Surg Pathol. , vol.35 , pp. 1679-1684
    • Bishop, J.A.1    Westra, W.H.2
  • 43
    • 84857647381 scopus 로고    scopus 로고
    • HPV-associated neuroendocrine carcinoma of the oropharynx: A rare new entity with potentially aggressive clinical behavior
    • Kraft S, Faquin WC, Krane JF. HPV-associated neuroendocrine carcinoma of the oropharynx: a rare new entity with potentially aggressive clinical behavior. Am J Surg Pathol. 2012;36:321-330.
    • (2012) Am J Surg Pathol. , vol.36 , pp. 321-330
    • Kraft, S.1    Faquin, W.C.2    Krane, J.F.3
  • 44
    • 84883798952 scopus 로고    scopus 로고
    • Spindle cell carcinomas of the head and neck rarely harbor transcriptionally-active human papillomavirus
    • Watson RF, Chernock RD, Wang X, et al. Spindle cell carcinomas of the head and neck rarely harbor transcriptionally-active human papillomavirus. Head Neck Pathol. 2013;7:250-257.
    • (2013) Head Neck Pathol. , vol.7 , pp. 250-257
    • Watson, R.F.1    Chernock, R.D.2    Wang, X.3
  • 45
    • 40349093242 scopus 로고    scopus 로고
    • Rising incidence of oropharyngeal cancer and the role of oncogenic human papilloma virus
    • Ernster JA, Sciotto CG, O'Brien MM, et al. Rising incidence of oropharyngeal cancer and the role of oncogenic human papilloma virus. Laryngoscope. 2007;117:2115-2128.
    • (2007) Laryngoscope. , vol.117 , pp. 2115-2128
    • Ernster, J.A.1    Sciotto, C.G.2    O'Brien, M.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.