Platelet Factor 4–Positive Thrombi Adhering to the Ventricles of a Ventricular Assist Device in Patients with Heparin-Induced Thrombocytopenia Type II

Transplantation Proceedings

Volumn 45, Issue 5, 2013, Pages 2013-2016

  Beiras Fernandez, A ^a   Kanzler, I ^a   Michel, S ^b   Sadoni, S ^b   Kilger, E ^b   Beiras, A ^c   Kur, F ^b  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ARGATROBAN; HEPARIN; POLYURETHAN; THROMBOCYTE FACTOR 4; THROMBOCYTE FACTOR 4 ANTIBODY; UNCLASSIFIED DRUG; ANTICOAGULANT AGENT;

ANTICOAGULATION; ARTICLE; BIOPSY; CASE REPORT; CLINICAL EXAMINATION; HEPARIN INDUCED THROMBOCYTOPENIA; HEPARIN INDUCED THROMBOCYTOPENIA TYPE II; HISTOLOGY; HUMAN; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE COUNT; THROMBOCYTE MEMBRANE; THROMBOSIS; VENTRICULAR ASSIST DEVICE; CHEMICALLY INDUCED; COMPLICATION; HEART ASSIST DEVICE; IMMUNOLOGY; METABOLISM; THROMBOCYTOPENIA; CHEMICALLY INDUCED DISORDER;

ANTIBODIES; ANTICOAGULANTS; HEART-ASSIST DEVICES; HEPARIN; HUMANS; PLATELET FACTOR 4; THROMBOCYTOPENIA; THROMBOSIS;

EID: 84893021580     PISSN: 00411345     EISSN: 18732623     Source Type: Journal    
DOI: 10.1016/j.transproceed.2013.01.045     Document Type: Article

References (13)

1. Koster, A., Sänger, S., Hansen, R., et al. Prevalence and persistence of heparin/platelet factor 4 antibodies in patients with heparin coated and noncoated ventricular assist devices. ASAIO J 46:3 (2000), 319–322.
2. Christiansen, S., Jahn, U.R., Meyer, J., et al. Anticoagulative management of patients requiring left ventricular assist device implantation and suffering from heparin-induced thrombocytopenia type II. Ann Thorac Surg 69 (2000), 774–777.
3. Davenport, A., Antibodies to heparin-platelet factor 4 complex: pathogenesis, epidemiology, and management of heparin-induced thrombocytopenia in hemodialysis. Am J Kidney Dis 54:2 (2009), 361–374.
4. Warkentin, T.E., Greinacher, A., Koster, A., Heparin-induced thrombocytopenia in patients with ventricular assist devices: are new prevention strategies required?. Ann Thorac Surg 87 (2009), 1633–1640.
5. Koster, A., Huebler, S., Potapov, E., et al. Impact of heparin-induced thrombocytopenia on outcome in patients with ventricular assist device support: single-institution experience in 358 consecutive patients. Ann Thorac Surg 83 (2007), 72–76.
6. Schmid, C., Weyand, M., Nabavi, D.G., et al. Cerebral and systemic embolization during left ventricular support with the Novacor N100 device. Ann Thorac Surg 65 (1998), 1703–1710.
7. Beiderlinden, M., Treschan, T., Gorlinger, K., et al. Argatroban in extracorporeal membrane oxygenation. Artif Organs 31:6 (2007), 461–465.
8. Swan, S.K., Hursting, M.J., The pharmacokinetics and pharmacodynamics of argatroban: effects of age, gender, and hepatic or renal dysfunction. Pharmacotherapy 20:3 (2000), 318–329.
9. Dolch, M.E., Frey, L., Hatz, R., et al. Extracorporeal membrane oxygenation bridging to lung transplant complicated by heparin-induced thrombocytopenia. Exp Clin Transplant 8:4 (2010), 329–332.
10. Keeling, D., Davidson, S., Watson, H., The management of heparin-induced thrombocytopenia. Br J Haematol 133:3 (2006), 259–269.
11. Bauer, C., Vichova, Z., French, P., et al. Extracorporeal membrane oxygenation with danaparoid sodium after massive pulmonary embolism. Anesth Analg 106:4 (2008), 1101–1103.
12. Dager, W.E., Gosselin, R.C., Yoshikawa, R., et al. Lepirudin in heparin-induced thrombocytopenia and extracorporeal membranous oxygenation. Ann Pharmacother 38:4 (2004), 598–601.
13. Koster, A., Loebe, M., Sodian, R., et al. Heparin antibodies and thromboembolism in heparin-coated and noncoated ventricular assist devices. J Thorac Cardiovasc Surg 121:2 (2001), 331–335.