Puberty in 2013: Unravelling the mystery of puberty

Nature Reviews Endocrinology

Volumn 10, Issue 2, 2014, Pages 67-69

  Ojeda, Sergio R ^a   Lomniczi, Alejandro ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 21; GONADORELIN; GONADOTROPIN; HISTONE H3; KISSPEPTIN; VASOPRESSIN;

ARCUATE NUCLEUS; DNA METHYLATION; ENDOCRINE FUNCTION; EPIGENETIC REPRESSION; EPIGENETICS; GENE; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; HISTONE MODIFICATION; HORMONE RELEASE; HUMAN; HYPOGONADISM; NERVE CELL; NERVE CELL NETWORK; NEUROENDOCRINOLOGY; NONHUMAN; PRECOCIOUS PUBERTY; PREPUBERTY; PRIORITY JOURNAL; PROMOTER REGION; PUBERTY; REPRODUCTION; REVIEW; RING FINGER MOTIF; SUPRACHIASMATIC NUCLEUS; SYNAPTIC INHIBITION;

ADOLESCENT; ANIMALS; EPIGENOMICS; FEMALE; HUMANS; MALE; MALNUTRITION; MODELS, ANIMAL; NEUROSECRETORY SYSTEMS; PUBERTY; TRANSCRIPTION, GENETIC;

EID: 84893018837     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2013.233     Document Type: Review

References (10)

1. Seminara, S. B. et al. The GPR54 gene as a regulator of puberty. N. Engl. J. Med. 349, 1614-1627 (2003).
2. de Roux, N. et al. Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc. Natl Acad. Sci. USA 100, 10972-10976 (2003).
3. Lomniczi, A., Wright, H., Castellano, J. M., Sonmez, K. & Ojeda, S. R. A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primates. Horm. Behav. 64, 175-186 (2013).
4. Sykiotis, G. P., Pitteloud, N., Seminara, S. B., Kaiser, U. B. & Crowley, W. F. Jr. Deciphering genetic disease in the genomic era: The model of GnRH deficiency. Sci. Transl. Med. 2, 32rv2 (2010).
5. Ojeda, S. R. & Terasawa, E. in Hormones, Brain and Behavior Vol. 4 (eds Pfaff, D. et al.) 589-659 (Elsevier, New York, 2002).
6. Pinilla, L., Aguilar, E., Dieguez, C., Millar, R. P. & Tena-Sempere, M. Kisspeptins and reproduction: Physiological roles and regulatory mechanisms. Physiol. Rev. 92, 1235-1316 (2012).
7. Lomniczi, A. et al. Epigenetic control of female puberty. Nat. Neurosci. 16, 281-289 (2013).
8. Abreu, A. P. et al. Central precocious puberty caused by mutations in the imprinted gene MKRN3. N. Engl. J. Med. 368, 2467-2475 (2013).
9. Jong, M. T. et al. A novel imprinted gene, encoding a RING zinc-finger protein, and overlapping antisense transcript in the Prader-Willi syndrome critical region. Hum. Mol. Genet. 8, 783-793 (1999).
10. Owen, B. M. et al. FGF21 contributes to neuroendocrine control of female reproduction. Nat. Med. 19, 1153-1156 (2013).